Cytotoxicity and mycotoxin production of shellfish-derived Penicillium spp., a risk for shellfish consumers (pages 385–392)
M. Geiger, Y. Guitton, M. Vansteelandt, I. Kerzaon, E. Blanchet, T. Robiou du Pont, J.C. Frisvad, P. Hess, Y.F. Pouchus and O. Grovel
Version of Record online: 6 SEP 2013 | DOI: 10.1111/lam.12143
Significance and Impact of the Study: Penicillium strains isolated from bivalve molluscs produce extracts exhibiting a higher cytotoxicity than extracts from Penicillium strains isolated from the surrounding marine environment. The use of a mussel-based medium for cultures of some shellfish-derived strains enhances the cytotoxicity of extracts when compared with classical media. The production of cytotoxic compounds and of the mycotoxin patulin on such a host-derived medium highlights a potential health risk for shellfish consumers.