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How to optimize HCV therapy in genotype 4 patients

  1. Gamal Esmat1,2,*,
  2. Mohamed El Kassas2,
  3. Mohamed Hassany2,
  4. Mohamed Esmat Gamil2,
  5. Maisa El Raziky1

Article first published online: 3 JAN 2013

DOI: 10.1111/liv.12059

Issue

Liver International

Liver International

Special Issue: Proceedings of the 6th Paris Hepatitis Conference, International Conference on the Management of Patients with Viral Hepatitis

Volume 33, Issue Supplement s1, pages 41–45, February 2013

Additional Information

How to Cite

Esmat, G., El Kassas, M., Hassany, M., Gamil, M. E. and El Raziky, M. (2013), How to optimize HCV therapy in genotype 4 patients. Liver International, 33: 41–45. doi: 10.1111/liv.12059

Author Information

  1. 1

    Endemic Medicine Department, Faculty of Medicine, Cairo University, Cairo, Egypt

  2. 2

    Tropical Medicine Department, National Hepatology & Tropical Medicine Research Institute, Cairo, Egypt

* Correspondence
Gamal Esmat, MD, Endemic Medicine Department, Faculty of Medicine, Cairo Univesrity, Cairo, Egypt
Tel: +(202) 235728360 - +(202) 235676138
Fax: +(202) 235728131 - + (202) 23682774
e-mail: gesmat@gamalesmat.com

Publication History

  1. Issue published online: 3 JAN 2013
  2. Article first published online: 3 JAN 2013

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Keywords:

  • genotype 4;
  • hepatitis C virus;
  • treatment predictors

Abstract

HCV is a worldwide disease with an estimated prevalence by WHO of 3%. Hepatitis C virus 4 is prevalent in Africa and the Middle East, especially Egypt. The treatment of HCV4 is affected by many factors, related to the virus itself (genotype, pretreatment viral load and prevalent quasispecies), to the host (genetic factors, age, ethnicity and liver histology), to the presence of comorbidities (obesity, insulin resistance and co-infections) and to the therapeutic drugs (type, dose and duration). Optimizing treatment is the goal of daily practice to obtain the best results for the patient.

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