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Review Article
Optimal management of HBV infection during pregnancy
Article first published online: 3 JAN 2013
DOI: 10.1111/liv.12060
© 2012 John Wiley & Sons A/S
Issue
Liver International
Special Issue: Proceedings of the 6th Paris Hepatitis Conference, International Conference on the Management of Patients with Viral Hepatitis
Volume 33, Issue Supplement s1, pages 188–194, February 2013
Additional Information
How to Cite
Piratvisuth, T. (2013), Optimal management of HBV infection during pregnancy. Liver International, 33: 188–194. doi: 10.1111/liv.12060
Publication History
- Issue published online: 3 JAN 2013
- Article first published online: 3 JAN 2013
- Abstract
- Article
- References
- Cited By
Keywords:
- hepatitis B virus infection;
- mother-to-child transmission;
- pregnancy
Abstract
Chronic hepatitis B virus (HBV) infection in pregnancy presents a unique and important challenge. Over 50% of chronic HBV carriers in endemic areas acquire infection vertically from their mothers. More importantly, over 90% of perinatally acquired infections progress to chronic HBV infection. Thus, management of chronic HBV during pregnancy and strategies to prevent mother-to-child transmission is an important step in eradicating or reducing the global burden of chronic hepatitis B. In addition, chronic HBV infection in pregnancy presents a unique clinical challenge because of the complex relationship between the physiological changes of pregnancy and the pathophysiological response to HBV. This review will present the current knowledge and a practical approach to management of HBV in pregnancy.