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Burden of liver disease in Brazil

Authors

  • Lysandro A. Nader,

    Corresponding author
    1. Department of Gastroenterology, School of Medicine, Universidade Federal de Pelotas (UFPEL), Pelotas, Brazil
    • Correspondence

      Dr. Lysandro Alsina Nader, Rua General Osorio,1184, 96020-000, Pelotas, RS, Brazil

      Tel: +51 55 53 91407575

      Fax: +51 55 53 30287833

      e-mail: lnader@terra.com.br

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  • Angelo A. de Mattos,

    1. Department of Gastroenterology, Graduate Program in Hepatology, Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, Brazil
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  • Gisele A. N. Bastos

    1. Public Health Department, Graduate Program in Hepatology, Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, Brazil
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Abstract

Background & Aims

The burden of liver diseases in the Brazilian population is still unknown. To assess the impact of liver diseases on hospital admissions and mortality within the framework of the Brazilian Unified Health System.

Methods

An analytical ecological observational study was carried out. Secondary data on hospital admissions and deaths because of liver disease were collected from the Unified Health System Information Technology Department (DATASUS) database, between 2001 and 2010. All liver diseases included in the International Classification of Diseases (ICD-10) were reviewed.

Results

Liver diseases were the eighth leading cause of death in Brazil. The prevalence of hospital admission because of liver disease during the period of analysis was 0.72% (853 571 hospitalizations), and the mortality rate was 3.34% (308 290 deaths). The mean age at hospital admission and death because of liver disease was 48.05 and 58.10 years respectively. Both hospitalization and death because of liver disease were more common among men, and followed an upward trend over the years. Cirrhosis was the main cause of hospital admissions and death by liver disease in Brazil. The South region of the country had the highest hospital admission rates because of liver disease in Brazil, whereas the Southeast region had the highest mortality rate.

Conclusion

This study provides evidence of the relevance of liver diseases within the framework of the Brazilian Unified Health System, and shows that the burden of these diseases is not only significant but progressive, at least in terms of hospital admissions and mortality rate.

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