Important aspects of oral paracoccidioidomycosis–a literature review
Article first published online: 23 OCT 2012
© 2012 Blackwell Verlag GmbH
Volume 56, Issue 3, pages 189–199, May 2013
How to Cite
de Abreu e Silva, M. À., Salum, F. G., Figueiredo, M. A. and Cherubini, K. (2013), Important aspects of oral paracoccidioidomycosis–a literature review. Mycoses, 56: 189–199. doi: 10.1111/myc.12017
- Issue published online: 12 APR 2013
- Article first published online: 23 OCT 2012
- Submitted for publication 6 July 2012 Revised 5 September 2012 Accepted for publication 25 September 2012
- Oral paracoccidioidomycosis;
- Paracoccidioides brasiliensis ;
- South American blastomycosis.
Paracoccidioidomycosis is a deep mycosis endemic to Latin America, with considerable morbidity and mortality. It is caused by the dimorphic fungus Paracoccidioides brasiliensis, which affects, among other organs in the human body, the oral cavity. Fungus virulence and immunocompetence of the host determine the establishment of infection or active disease, whose severity and clinical behaviour depend mostly on the cellular immune response of the host. Often, oral lesions constitute the first sign and site of confirmation of diagnosis, which in most cases is delayed. The success of the treatment depends on early and correct diagnosis, as well as on the patient’s adherence to the drug therapy.