Get access

Important aspects of oral paracoccidioidomycosis–a literature review

Authors

  • Mariana Àlvares de Abreu e Silva,

    1. Postgraduate Program of Dental College, Pontifical Catholic University of Rio Grande do Sul, Porto Alegre, Brazil
    2. Stomatology Department, Hospital São Lucas, Pontifical Catholic University of Rio Grande do Sul, Porto Alegre, Brazil
    Search for more papers by this author
  • Fernanda Gonçalves Salum,

    1. Postgraduate Program of Dental College, Pontifical Catholic University of Rio Grande do Sul, Porto Alegre, Brazil
    2. Stomatology Department, Hospital São Lucas, Pontifical Catholic University of Rio Grande do Sul, Porto Alegre, Brazil
    Search for more papers by this author
  • Maria Antonia Figueiredo,

    1. Postgraduate Program of Dental College, Pontifical Catholic University of Rio Grande do Sul, Porto Alegre, Brazil
    2. Stomatology Department, Hospital São Lucas, Pontifical Catholic University of Rio Grande do Sul, Porto Alegre, Brazil
    Search for more papers by this author
  • Karen Cherubini

    1. Postgraduate Program of Dental College, Pontifical Catholic University of Rio Grande do Sul, Porto Alegre, Brazil
    2. Stomatology Department, Hospital São Lucas, Pontifical Catholic University of Rio Grande do Sul, Porto Alegre, Brazil
    Search for more papers by this author

K. Cherubini, Serviço de Estomatologia, Hospital São Lucas – PUCRS Av. Ipiranga, 6690/231, Porto Alegre 90610-000, Brazil.
Tel./Fax: +55 51 33203254.
E-mail: karen.cherubini@pucrs.br

Summary

Paracoccidioidomycosis is a deep mycosis endemic to Latin America, with considerable morbidity and mortality. It is caused by the dimorphic fungus Paracoccidioides brasiliensis, which affects, among other organs in the human body, the oral cavity. Fungus virulence and immunocompetence of the host determine the establishment of infection or active disease, whose severity and clinical behaviour depend mostly on the cellular immune response of the host. Often, oral lesions constitute the first sign and site of confirmation of diagnosis, which in most cases is delayed. The success of the treatment depends on early and correct diagnosis, as well as on the patient’s adherence to the drug therapy.

Ancillary