In vitro antifungal susceptibility of clinical isolates of Arthrographis kalrae, a poorly known opportunistic fungus

Authors

  • Marcelo Sandoval-Denis,

    1. Unitat de Microbiologia, Facultat de Medicina i Ciències de la Salut, Universitat Rovira i Virgili, IISPV, Reus, Spain
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  • Alejandra Giraldo,

    1. Unitat de Microbiologia, Facultat de Medicina i Ciències de la Salut, Universitat Rovira i Virgili, IISPV, Reus, Spain
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  • Deanna A. Sutton,

    1. Fungus Testing Laboratory, Department of Pathology, University of Texas Health Science Center, San Antonio, TX, USA
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  • Annette W. Fothergill,

    1. Fungus Testing Laboratory, Department of Pathology, University of Texas Health Science Center, San Antonio, TX, USA
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  • Josep Guarro

    Corresponding author
    1. Unitat de Microbiologia, Facultat de Medicina i Ciències de la Salut, Universitat Rovira i Virgili, IISPV, Reus, Spain
    • Correspondence: J. Guarro, Unitat de Microbiologia, Facultat de Medicina, Universitat Rovira i Virgili, Carrer Sant Llorenc, 21. 43201. Reus, Spain.

      Tel.: +34 977 759 359. Fax: +34 977 759 322.

      E-mail: josep.guarro@urv.cat.

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Summary

The in vitro antifungal activity of amphotericin B (AMB), itraconazole, voriconazole, posaconazole, terbinafine (TRB), caspofungin, anidulafungin and micafungin were evaluated by a broth microdilution technique against 22 isolates of Arthrographis kalrae of clinical origin. TRB showed the highest activity, followed by the azoles, particularly posaconazole. AMB exerted low activity whereas the echinocandins showed almost no antifungal activity.

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