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Figure S1. Representative images of frozen muscle sections obtained from s-IBM patients. (A) Rimmed vacuoles and scattered inflammatory cells stained with Gomori modified trichrome. (B) Immunostaining with SMI-31 antibody reveals granules of accumulated paired helical filaments distributed among the sarcoplasm and subsarcolemmal region of small atrophic s-IBM fibres. Scale bars: 50 μm.

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