These authors contributed equally to this work as junior.
Differential gene expression in multiple neurological, inflammatory and connective tissue pathways in a spontaneous model of human small vessel stroke
Article first published online: 17 NOV 2014
© 2014 The Authors. Neuropathology and Applied Neurobiology published by John Wiley & Sons Ltd on behalf of British Neuropathological Society.
This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
Neuropathology and Applied Neurobiology
Volume 40, Issue 7, pages 855–872, December 2014
How to Cite
Bailey, E. L., McBride, M. W., Beattie, W., McClure, J. D., Graham, D., Dominiczak, A. F., Sudlow, C. L.M., Smith, C. and Wardlaw, J. M. (2014), Differential gene expression in multiple neurological, inflammatory and connective tissue pathways in a spontaneous model of human small vessel stroke. Neuropathology and Applied Neurobiology, 40: 855–872. doi: 10.1111/nan.12116
- Issue published online: 17 NOV 2014
- Article first published online: 17 NOV 2014
- Accepted manuscript online: 13 JAN 2014 02:01AM EST
- Manuscript Accepted: 8 JAN 2014
- Manuscript Received: 12 AUG 2013
- Medical Research Council PhD studentship
- Newby Fund (University of Edinburgh)
- British Neuropathological Society
- Scottish Funding Council
- British Heart Foundation Chair and Programme grant funding. Grant Numbers: CH98001, RG/07/005
- European Community's Seventh Framework Programme (FP7/2007-2013). Grant Number: HEALTH-F4-2010-241504
Table S1. Details of differentially expressed genes in the ‘neurological disorders’ functional pathway identified in IPA.
Table S2. Details of differentially expressed genes in the ‘inflammation’ functional pathway identified in IPA.
Table S3. Genes from the microarray chosen for quantitative validation with qRT-PCR, the reasons and data obtained from qRT-PCR analysis. Numbers are the mean difference (± the standard error of the mean) in CT values between the gene of interest and the house keeper gene GAPDH for SHRSP and WKY at ages 5–21 weeks and from frontal (F) and mid-coronal (M) brain sections.
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