Neuropathology and Applied Neurobiology

© British Neuropathological Society

Cover image for Vol. 43 Issue 4

June 2017

Volume 43, Issue 4

Pages 277–365

  1. Issue Information

    1. Top of page
    2. Issue Information
    3. In This Issue
    4. Review
    5. Original Articles
    6. Scientific Correspondence
    1. Issue Information (page 277)

      Version of Record online: 22 MAY 2017 | DOI: 10.1111/nan.12352

  2. In This Issue

    1. Top of page
    2. Issue Information
    3. In This Issue
    4. Review
    5. Original Articles
    6. Scientific Correspondence
    1. In This Issue (pages 279–280)

      Version of Record online: 22 MAY 2017 | DOI: 10.1111/nan.12407

  3. Review

    1. Top of page
    2. Issue Information
    3. In This Issue
    4. Review
    5. Original Articles
    6. Scientific Correspondence
    1. Review: Astrocytes in Alzheimer's disease and other age-associated dementias: a supporting player with a central role (pages 281–298)

      C. J. Garwood, L. E. Ratcliffe, J. E. Simpson, P. R. Heath, P. G. Ince and S. B. Wharton

      Version of Record online: 22 MAY 2017 | DOI: 10.1111/nan.12338

      Thumbnail image of graphical abstract

      This review provides a broad overview of the role of astrocytic populations in the healthy brain and their role in ageing and neurodegenerative diseases with an emphasis on Alzheimer's disease. Perturbation of astrocyte function may contribute to the pathogenesis of dementia and may present an additional therapeutic target.

  4. Original Articles

    1. Top of page
    2. Issue Information
    3. In This Issue
    4. Review
    5. Original Articles
    6. Scientific Correspondence
    1. Effect of systemic transplantation of bone marrow-derived mesenchymal stem cells on neuropathology markers in APP/PS1 Alzheimer mice (pages 299–314)

      Y. Naaldijk, C. Jäger, C. Fabian, C. Leovsky, A. Blüher, L. Rudolph, A. Hinze and A. Stolzing

      Version of Record online: 19 APR 2016 | DOI: 10.1111/nan.12319

      Thumbnail image of graphical abstract

      Systemically administered mesenchymal stem cells can localise to the brain, reduce the size of Aβ deposits and modulate immune mechanisms in a mouse model of Alzheimer's disease.

    2. Progression of alpha-synuclein pathology in multiple system atrophy of the cerebellar type (pages 315–329)

      J. Brettschneider, D. J. Irwin, S. Boluda, M. D. Byrne, L. Fang, E. B. Lee, J. L. Robinson, E. Suh, V. M. Van Deerlin, J. B. Toledo, M. Grossman, H. Hurtig, R. Dengler, S. Petri, V. M.-Y. Lee and J. Q. Trojanowski

      Version of Record online: 18 OCT 2016 | DOI: 10.1111/nan.12362

      Thumbnail image of graphical abstract

      In the cerebellar sub-type of multiple system atrophy (MSA-C) glial cytoplasmic inclusions first involve subcortical cerebellar white matter and brainstem cerebellar projections with later involvement of additional brain regions and neurodegeneration. The study contributes to determining whether prion-like propagation of misfolded proteins along anatomical pathways may be important in MSA.

    3. Evidence of early defects in Cajal–Retzius cell localization during brain development in a mouse model of dystroglycanopathy (pages 330–345)

      H. S. Booler, V. Pagalday-Vergara, J. L. Williams, M. Hopkinson and S. C. Brown

      Version of Record online: 24 MAR 2017 | DOI: 10.1111/nan.12376

      Thumbnail image of graphical abstract

      Brain involvement in severe phenotypes of dystroglycanopathies includes abnormal cortical neuronal migration leading to type II, or cobblestone, lissencephaly. In embryonic Fkrp-deficient mice (FKRPKD) basement membrane abnormalities and mislocalisation of Cajal-Retzius cells are early events in the development of cortical defects.

  5. Scientific Correspondence

    1. Top of page
    2. Issue Information
    3. In This Issue
    4. Review
    5. Original Articles
    6. Scientific Correspondence
    1. You have full text access to this OnlineOpen article
      Free of acrylamide sodium dodecyl sulphate (SDS)-based tissue clearing (FASTClear): a novel protocol of tissue clearing for three-dimensional visualization of human brain tissues (pages 346–351)

      A. K. L. Liu, H. M. Lai, R. C.-C. Chang and S. M. Gentleman

      Version of Record online: 19 APR 2017 | DOI: 10.1111/nan.12361

    2. Conjoint FTLD-FUS of the neuronal intermediate filament inclusion disease type, progressive supranuclear palsy and Alzheimer's pathology presenting as parkinsonism with early falls and late hallucinations, psychosis and dementia (pages 352–357)

      Y. Compta, O. Ramos-Campoy, O. Grau-Rivera, M. Colom-Cadena, J. Clarimón, M. J. Martí and E. Gelpi

      Version of Record online: 22 MAY 2017 | DOI: 10.1111/nan.12340

    3. You have full text access to this OnlineOpen article
      Deregulated expression of EZH2 in congenital brainstem disconnection (pages 358–365)

      P. G. Barth, E. Aronica, S. Fox, K. Fluiter, M. A. J. Weterman, A. Poretti, D. C. Miller, E. Boltshauser, B. Harding, M. Santi and F. Baas

      Version of Record online: 22 MAY 2017 | DOI: 10.1111/nan.12368

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