Neuropathology and Applied Neurobiology

© British Neuropathological Society

Cover image for Vol. 43 Issue 5

August 2017

Volume 43, Issue 5

Pages 367–462

  1. Issue Information

    1. Top of page
    2. Issue Information
    3. In This Issue
    4. Editorial
    5. Original Articles
    6. Letters to the Editor
    7. Scientific Correspondences
    1. Issue Information (page 367)

      Version of Record online: 11 JUL 2017 | DOI: 10.1111/nan.12354

  2. In This Issue

    1. Top of page
    2. Issue Information
    3. In This Issue
    4. Editorial
    5. Original Articles
    6. Letters to the Editor
    7. Scientific Correspondences
    1. In This Issue (pages 369–370)

      Version of Record online: 11 JUL 2017 | DOI: 10.1111/nan.12421

  3. Editorial

    1. Top of page
    2. Issue Information
    3. In This Issue
    4. Editorial
    5. Original Articles
    6. Letters to the Editor
    7. Scientific Correspondences
    1. You have free access to this content
      Tau aggregates: where, when, why and what consequences? (pages 371–372)

      M. P. Frosch

      Version of Record online: 11 JUL 2017 | DOI: 10.1111/nan.12400

      The significance of tau pathology in the locus coeruleus and dorsal raphe nucleus in Alzheimer's disease is considered, both in terms of our understanding of disease mechanisms, and also the implications for treatment strategies.

  4. Original Articles

    1. Top of page
    2. Issue Information
    3. In This Issue
    4. Editorial
    5. Original Articles
    6. Letters to the Editor
    7. Scientific Correspondences
    1. Locus coeruleus at asymptomatic early and middle Braak stages of neurofibrillary tangle pathology (pages 373–392)

      P. Andrés-Benito, V. Fernández-Dueñas, M. Carmona, L. A. Escobar, B. Torrejón-Escribano, E. Aso, F. Ciruela and I. Ferrer

      Version of Record online: 19 APR 2017 | DOI: 10.1111/nan.12386

      Thumbnail image of graphical abstract

      Novel alterations in metabolic pathways in the locus coeruleus accompany tau pathology in pre-symptomatic Alzheimer's disease have implications for disease mechanisms and developing treatment strategies.

    2. Quantifying the accretion of hyperphosphorylated tau in the locus coeruleus and dorsal raphe nucleus: the pathological building blocks of early Alzheimer's disease (pages 393–408)

      A. J. Ehrenberg, A. K. Nguy, P. Theofilas, S. Dunlop, C. K. Suemoto, A. T. Di Lorenzo Alho, R. P. Leite, R. Diehl Rodriguez, M. B. Mejia, U. Rüb, J. M. Farfel, R. E. de Lucena Ferretti-Rebustini, C. F. Nascimento, R. Nitrini, C. A. Pasquallucci, W. Jacob-Filho, B. Miller, W. W. Seeley, H. Heinsen and L. T. Grinberg

      Version of Record online: 31 MAR 2017 | DOI: 10.1111/nan.12387

      Thumbnail image of graphical abstract

      Stereological analysis of tau pathology in the locus coeruleus and dorsal raphe nucleus in early Alzheimer's disease demonstrate that early involvement of brain stem nuclei has important functional implications.

    3. You have full text access to this OnlineOpen article
      Microinfarcts in an older population-representative brain donor cohort (MRC CFAS): Prevalence, relation to dementia and mobility, and implications for the evaluation of cerebral Small Vessel Disease (pages 409–418)

      P. G. Ince, T. Minett, G. Forster, C. Brayne, S. B. Wharton and on behalf of the Medical Research Council Cognitive Function and Ageing Neuropathology Study

      Version of Record online: 28 OCT 2016 | DOI: 10.1111/nan.12363

      Thumbnail image of graphical abstract

      Microinfarcts are common in the brains of elderly individuals correlating with cognitive impairment, impaired mobility and falls. They should be included in the neuropathological assessment of small vessel disease.

    4. Dock1 promotes the mesenchymal transition of glioma and is modulated by MiR-31 (pages 419–432)

      Baogang Zhang, Hongli Li, Chonggao Yin, Xuemei Sun, Shuxian Zheng, Changjie Zhang, Lihong Shi, Yuqing Liu and Shijun Lu

      Version of Record online: 28 APR 2016 | DOI: 10.1111/nan.12321

      Thumbnail image of graphical abstract

      Manipulating the levels of Dock1 and MiR-31 can influence invasion by glioma cells and Dock1 expression is modulated by MiR-31. Improved understanding invasion and migration by glioma cells may provide new approaches to treatment.

    5. Meningeal SWI/SNF related, matrix-associated, actin-dependent regulator of chromatin, subfamily B member 1 (SMARCB1)-deficient tumours: an emerging group of meningeal tumours (pages 433–449)

      B. Dadone, D. Fontaine, L. Mondot, G. Cristofari, A. Jouvet, C. Godfraind, P. Varlet, D. Ranchère-Vince, J.-M. Coindre, L. Gastaud, C. Baudoin, A.-C. Peyron, A. Thyss, M. Coutts, J.-F. Michiels, F. Pedeutour, F. Burel-Vandenbos and the RENOP

      Version of Record online: 28 DEC 2016 | DOI: 10.1111/nan.12364

      Thumbnail image of graphical abstract

      This newly described group of primary meningeal SMARCB1-deficient tumours expands our understanding of difficult to classify primary meningeal tumours.

  5. Letters to the Editor

    1. Top of page
    2. Issue Information
    3. In This Issue
    4. Editorial
    5. Original Articles
    6. Letters to the Editor
    7. Scientific Correspondences
    1. Commentary on human adult neurogenesis across the ages: An immunohistochemical study (pages 450–451)

      Gianluca Marucci

      Version of Record online: 11 JUL 2017 | DOI: 10.1111/nan.12377

    2. Response to: Comment on ‘Human adult neurogenesis across the ages: An immunohistochemical study’ (pages 452–454)

      C. V. Dennis, L. S. Suh, M. L. Rodriguez, J. J. Kril and G. T. Sutherland

      Version of Record online: 11 JUL 2017 | DOI: 10.1111/nan.12394

  6. Scientific Correspondences

    1. Top of page
    2. Issue Information
    3. In This Issue
    4. Editorial
    5. Original Articles
    6. Letters to the Editor
    7. Scientific Correspondences
    1. Metastatic renal cell carcinoma metastasising into a cerebral cavernous malformation (pages 455–457)

      J. Shapey, R. Phadke and N. Kitchen

      Version of Record online: 11 JUL 2017 | DOI: 10.1111/nan.12345

    2. K27M midline gliomas display malignant progression by imaging and histology (pages 458–462)

      F. J. Vettermann, J. E. Neumann, B. Suchorska, P. Bartenstein, A. Giese, M. M. Dorostkar, N. L. Albert and U. Schüller

      Version of Record online: 11 JUL 2017 | DOI: 10.1111/nan.12371

SEARCH

SEARCH BY CITATION