Nephrology

Cover image for Vol. 15 Issue 1

February 2010

Volume 15, Issue 1

Pages 1–136

  1. REVIEW ARTICLE

    1. Top of page
    2. REVIEW ARTICLE
    3. CLINICAL RESEARCH FOR NEPHROLOGISTS
    4. EDITORIAL
    5. DIALYSIS
    6. EVIDENCE-BASED NEPHROLOGY
    7. INTEGRATIVE BIOLOGY
    8. NEPHROLOGY IN HIGH RISK POPULATIONS
    9. PATHOLOGY, IMMUNOLOGY AND INFLAMMATION
    10. PROGRESSIVE CHRONIC RENAL DISEASE
    11. TRANSPLANTATION
    12. INSTRUCTIVE CASES/IMAGES
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      Spontaneous animal model, ddY mouse, for studying the pathogenesis and treatment in patients with immunoglobulin A nephropathy (pages 1–6)

      YASUHIKO TOMINO

      Version of Record online: 18 NOV 2009 | DOI: 10.1111/j.1440-1797.2009.01251.x

      A major limitation in the study of immunoglobulin (Ig)A nephropathy is the lack of suitable animal models. This review describes ddY mice which spontaneously develop mild to moderate IgA nephropathy. This model provides opportunities for genetic analysis of the disease and for testing established and novel therapies for IgA nephropathy.

  2. CLINICAL RESEARCH FOR NEPHROLOGISTS

    1. Top of page
    2. REVIEW ARTICLE
    3. CLINICAL RESEARCH FOR NEPHROLOGISTS
    4. EDITORIAL
    5. DIALYSIS
    6. EVIDENCE-BASED NEPHROLOGY
    7. INTEGRATIVE BIOLOGY
    8. NEPHROLOGY IN HIGH RISK POPULATIONS
    9. PATHOLOGY, IMMUNOLOGY AND INFLAMMATION
    10. PROGRESSIVE CHRONIC RENAL DISEASE
    11. TRANSPLANTATION
    12. INSTRUCTIVE CASES/IMAGES
    1. Clinical research for nephrologists: a practical series (page 7)

      JONATHAN C CRAIG and CARMEL HAWLEY

      Version of Record online: 11 FEB 2010 | DOI: 10.1111/j.1440-1797.2009.01265.x

    2. Asking the right question and finding the right answers (pages 8–11)

      NICHOLAS B CROSS, JONATHAN C CRAIG and ANGELA C WEBSTER

      Version of Record online: 17 DEC 2009 | DOI: 10.1111/j.1440-1797.2009.01264.x

      The basis for evidence based practice requires the generation and ‘framing’ of questions to provide the best answer. This review seeks to identify the information that you will need to answer your question.

    3. How to get the most from the medical literature: Searching the medical literature effectively (pages 12–19)

      ANGELA C WEBSTER, NICHOLAS B CROSS, RUTH MITCHELL and JONATHAN C CRAIG

      Version of Record online: 17 DEC 2009 | DOI: 10.1111/j.1440-1797.2009.01263.x

      This review outlines the most time-efficient and effective strategies to search the literature to answer targeted clinical questions. You are taken through a step-by-step approach to enable you to best utilise current contemporary search tools and databases.

  3. EDITORIAL

    1. Top of page
    2. REVIEW ARTICLE
    3. CLINICAL RESEARCH FOR NEPHROLOGISTS
    4. EDITORIAL
    5. DIALYSIS
    6. EVIDENCE-BASED NEPHROLOGY
    7. INTEGRATIVE BIOLOGY
    8. NEPHROLOGY IN HIGH RISK POPULATIONS
    9. PATHOLOGY, IMMUNOLOGY AND INFLAMMATION
    10. PROGRESSIVE CHRONIC RENAL DISEASE
    11. TRANSPLANTATION
    12. INSTRUCTIVE CASES/IMAGES
  4. DIALYSIS

    1. Top of page
    2. REVIEW ARTICLE
    3. CLINICAL RESEARCH FOR NEPHROLOGISTS
    4. EDITORIAL
    5. DIALYSIS
    6. EVIDENCE-BASED NEPHROLOGY
    7. INTEGRATIVE BIOLOGY
    8. NEPHROLOGY IN HIGH RISK POPULATIONS
    9. PATHOLOGY, IMMUNOLOGY AND INFLAMMATION
    10. PROGRESSIVE CHRONIC RENAL DISEASE
    11. TRANSPLANTATION
    12. INSTRUCTIVE CASES/IMAGES
    1. Neutrophil gelatinase-associated lipocalin levels in chronic haemodialysis patients (pages 23–26)

      DAVIDE BOLIGNANO, GIUSEPPE COPPOLINO, ADOLFO ROMEO, ANTONIO LACQUANITI and MICHELE BUEMI

      Version of Record online: 11 FEB 2010 | DOI: 10.1111/j.1440-1797.2009.01163.x

      Hemodialysis patients were found to have increased levels of circulating NGAL; levels fell with dialysis and this correlated with Kt/V.

    2. Effect of renin–angiotensin system inhibitors on prevention of peritoneal fibrosis in peritoneal dialysis patients (pages 27–32)

      SUN JING, YU KEZHOU, ZHANG HONG, WANG QUN and WANG RONG

      Version of Record online: 26 MAY 2009 | DOI: 10.1111/j.1440-1797.2009.01162.x

      Angiotensin-converting enzyme inhibitor (ACEI) or angiotensin receptor blocker (ARB) use was shown to delay the rate of decline of RRF and the loss of peritoneal ultrafiltration, effectively protecting against the development of peritoneal fibrosis in long-term peritoneal dialysis.

    3. Regulatory T cells/T-helper cell 17 functional imbalance in uraemic patients on maintenance haemodialysis: A pivotal link between microinflammation and adverse cardiovascular events (pages 33–41)

      JIANBIN ZHANG, GAN HUA, XIAOGANG ZHANG, RUYAN TONG, XIAOGANG DU and ZHENGRONG LI

      Version of Record online: 30 JUN 2009 | DOI: 10.1111/j.1440-1797.2009.01172.x

      A Thelper/Treg imbalance was identified in uremic patients and was associated with the development of acute cardiovascular events, myocardial injury, and micro-inflammation.

    4. Comparison of parenteral iron sucrose and ferric chloride during erythropoietin therapy of haemodialysis patients (pages 42–47)

      CHIH-JEN WU, HSIN-CHANG LIN, KUN-FENG LEE, CHIH-KUANG CHUANG, YI-CHOU CHEN and HAN-HSIANG CHEN

      Version of Record online: 26 MAY 2009 | DOI: 10.1111/j.1440-1797.2009.01160.x

      Iron sucrose and Fe chloride were shown to be equally safe and effective in the treatment of hemodialysis patients with anemia.

  5. EVIDENCE-BASED NEPHROLOGY

    1. Top of page
    2. REVIEW ARTICLE
    3. CLINICAL RESEARCH FOR NEPHROLOGISTS
    4. EDITORIAL
    5. DIALYSIS
    6. EVIDENCE-BASED NEPHROLOGY
    7. INTEGRATIVE BIOLOGY
    8. NEPHROLOGY IN HIGH RISK POPULATIONS
    9. PATHOLOGY, IMMUNOLOGY AND INFLAMMATION
    10. PROGRESSIVE CHRONIC RENAL DISEASE
    11. TRANSPLANTATION
    12. INSTRUCTIVE CASES/IMAGES
    1. Opinions on the content and effects of the Caring for Australasians with Renal Impairment (CARI) Guidelines: A survey of renal nurses and comparison with the opinions of nephrologists in Australasia (pages 48–53)

      MICHELLE J IRVING, DAVID W JOHNSON, STEPHEN MCDONALD, ROWAN G WALKER, MICHAEL S FROMMER, DEIRDRE FETHERSTONHAUGH, PAMELA DEANS and JONATHAN C CRAIG

      Version of Record online: 13 JUL 2009 | DOI: 10.1111/j.1440-1797.2009.01191.x

      Repeated surveys in 2002 and 2006 amongst renal nurses in Australian and New Zealand has shown the increased value and use of the CARI Guidelines in nursing practices. Findings suggest greater input from renal nurses in regard to content and the dissemination of the guidelines would be beneficial.

  6. INTEGRATIVE BIOLOGY

    1. Top of page
    2. REVIEW ARTICLE
    3. CLINICAL RESEARCH FOR NEPHROLOGISTS
    4. EDITORIAL
    5. DIALYSIS
    6. EVIDENCE-BASED NEPHROLOGY
    7. INTEGRATIVE BIOLOGY
    8. NEPHROLOGY IN HIGH RISK POPULATIONS
    9. PATHOLOGY, IMMUNOLOGY AND INFLAMMATION
    10. PROGRESSIVE CHRONIC RENAL DISEASE
    11. TRANSPLANTATION
    12. INSTRUCTIVE CASES/IMAGES
    1. Systemic disorders of calcium dynamics in rats with adenine-induced renal failure: Implication for chronic kidney disease-related complications (pages 54–62)

      RYUJI IKEDA, YASUO IMAI, WAKAKO MARUYAMA and KAZUSHIGE MIZOGUCHI

      Version of Record online: 26 MAY 2009 | DOI: 10.1111/j.1440-1797.2009.01161.x

      Severe abnormalities of Ca dynamics were found in adenine-induced renal failure rats including a dysfunction of intestinal Ca absorption, preferential Ca deposition in soft tissues but not in the bone and a higher rate of urinary Ca excretion.

    2. Urinary proteins from patients with nephrotic syndrome alters the signalling proteins regulating epithelial–mesenchymal transition (pages 63–74)

      QIONG WEN, ZHAO HUANG, SHU-FENG ZHOU, XIAO-YAN LI, NING LUO and XUE-QING YU

      Version of Record online: 6 MAY 2009 | DOI: 10.1111/j.1440-1797.2009.01152.x

      Patients with MCD and FSGS had significant changes in the expression of several EMT-related urinary proteins through activation ERK1/2 and p38 signaling pathways. Further studies to explore the molecular mechanisms behind the distinct clinical features of different types of nephrotic syndrome are warranted.

    3. Thiazolidinedione attenuate proteinuria and glomerulosclerosis in Adriamycin-induced nephropathy rats via slit diaphragm protection (pages 75–83)

      HUA-FENG LIU, LI-QIN GUO, YU-YING HUANG, KENG CHEN, JING-LI TAO, SHANG-MEI LI and XIAO-WEN CHEN

      Version of Record online: 23 APR 2009 | DOI: 10.1111/j.1440-1797.2009.01146.x

      This study provides direct evidence that the PPAR-γ agonist, rosiglitazone, can protect against the loss of podocyte foot processes and down-regulation of podocyte slit diaphragm proteins in experimental focal and segmental glomerulosclerosis. Interestingly, rosiglitazone reduced the degree of glomerulosclerosis and proteinuria, but did not prevent the loss of WT-1+ podocytes.

  7. NEPHROLOGY IN HIGH RISK POPULATIONS

    1. Top of page
    2. REVIEW ARTICLE
    3. CLINICAL RESEARCH FOR NEPHROLOGISTS
    4. EDITORIAL
    5. DIALYSIS
    6. EVIDENCE-BASED NEPHROLOGY
    7. INTEGRATIVE BIOLOGY
    8. NEPHROLOGY IN HIGH RISK POPULATIONS
    9. PATHOLOGY, IMMUNOLOGY AND INFLAMMATION
    10. PROGRESSIVE CHRONIC RENAL DISEASE
    11. TRANSPLANTATION
    12. INSTRUCTIVE CASES/IMAGES
    1. Metabolic syndrome and the development of chronic kidney disease among 118 924 non-diabetic Taiwanese in a retrospective cohort (pages 84–92)

      FENG SUN, QIUSHAN TAO and SIYAN ZHAN

      Version of Record online: 23 APR 2009 | DOI: 10.1111/j.1440-1797.2009.01150.x

      The relationship between metabolic syndrome and the development of CKD was examined using a large sample of non-diabetics in Taiwan. Metabolic syndrome was significantly related with the development of CKD and amongst metabolic components, central obesity, high blood pressure and high triglycerides were major factors contributing to new-onset CKD.

  8. PATHOLOGY, IMMUNOLOGY AND INFLAMMATION

    1. Top of page
    2. REVIEW ARTICLE
    3. CLINICAL RESEARCH FOR NEPHROLOGISTS
    4. EDITORIAL
    5. DIALYSIS
    6. EVIDENCE-BASED NEPHROLOGY
    7. INTEGRATIVE BIOLOGY
    8. NEPHROLOGY IN HIGH RISK POPULATIONS
    9. PATHOLOGY, IMMUNOLOGY AND INFLAMMATION
    10. PROGRESSIVE CHRONIC RENAL DISEASE
    11. TRANSPLANTATION
    12. INSTRUCTIVE CASES/IMAGES
    1. Renoprotective effects of asialoerythropoietin in diabetic mice against ischaemia–reperfusion-induced acute kidney injury (pages 93–101)

      JUN NAKAZAWA, KEIJI ISSHIKI, TOSHIRO SUGIMOTO, SHIN-ICHI ARAKI, SHINJI KUME, YUKIYO YOKOMAKU, MASAMI CHIN-KANASAKI, MASAYOSHI SAKAGUCHI, DAISUKE KOYA, MASAKAZU HANEDA, ATSUNORI KASHIWAGI and TAKASHI UZU

      Version of Record online: 11 JUN 2009 | DOI: 10.1111/j.1440-1797.2009.01170.x

      The renoprotective effects of asialoerythropoietin on acute kidney injury may be mediated through the induction of bcl-2 and BMP-7. Suppression of bcl-2 and BMP-7 could explain the acceleration of renal damage after ischemia-reperfusion injury in the diabetic kidney.

    2. Clinical and pathological features of renal amyloidosis: An analysis of 32 patients in a single Chinese centre (pages 102–107)

      ZHEN QU, XIN ZHENG, SU-XIA WANG, JIE AO, FU-DE ZHOU, MIN CHEN and GANG LIU

      Version of Record online: 11 FEB 2010 | DOI: 10.1111/j.1440-1797.2009.01127.x

      Recommendations to improve the early and accurate diagnosis of renal amyloidosis are shown to include clinical suspicion, electron microscopic examination and other pathological methods of identification and classification.

  9. PROGRESSIVE CHRONIC RENAL DISEASE

    1. Top of page
    2. REVIEW ARTICLE
    3. CLINICAL RESEARCH FOR NEPHROLOGISTS
    4. EDITORIAL
    5. DIALYSIS
    6. EVIDENCE-BASED NEPHROLOGY
    7. INTEGRATIVE BIOLOGY
    8. NEPHROLOGY IN HIGH RISK POPULATIONS
    9. PATHOLOGY, IMMUNOLOGY AND INFLAMMATION
    10. PROGRESSIVE CHRONIC RENAL DISEASE
    11. TRANSPLANTATION
    12. INSTRUCTIVE CASES/IMAGES
    1. Chronic kidney disease care program improves quality of pre-end-stage renal disease care and reduces medical costs (pages 108–115)

      SHU-YI WEI, YONG-YUAN CHANG, LIH-WEN MAU, MING-YEN LIN, HERNG-CHIA CHIU, JER-CHIA TSAI, CHIH-JEN HUANG, HUNG-CHUN CHEN and SHANG-JYH HWANG

      Version of Record online: 6 MAY 2009 | DOI: 10.1111/j.1440-1797.2009.01154.x

      A CKD Care Program is found to help pre-ESRD patients prepare for dialysis initiation and is associated with a reduced probability of emergency dialysis and hospitalization and lowered medical costs.

    2. Clinical effectiveness of steroid pulse therapy combined with tonsillectomy in patients with immunoglobulin A nephropathy presenting glomerular haematuria and minimal proteinuria (pages 116–123)

      TAKEHIKO KAWAGUCHI, NORIO IEIRI, SHIN YAMAZAKI, YASUAKI HAYASHINO, BRENDA GILLESPIE, MARIKO MIYAZAKI, YOSHIO TAGUMA, SHUNICHI FUKUHARA and OSAMU HOTTA

      Version of Record online: 23 APR 2009 | DOI: 10.1111/j.1440-1797.2009.01147.x

      Steroid pulse therapy combined with tonsillectomy (ST) is shown effective in clinical remission in this study of patients with IgAN presenting with minor urinary abnormalities.

  10. TRANSPLANTATION

    1. Top of page
    2. REVIEW ARTICLE
    3. CLINICAL RESEARCH FOR NEPHROLOGISTS
    4. EDITORIAL
    5. DIALYSIS
    6. EVIDENCE-BASED NEPHROLOGY
    7. INTEGRATIVE BIOLOGY
    8. NEPHROLOGY IN HIGH RISK POPULATIONS
    9. PATHOLOGY, IMMUNOLOGY AND INFLAMMATION
    10. PROGRESSIVE CHRONIC RENAL DISEASE
    11. TRANSPLANTATION
    12. INSTRUCTIVE CASES/IMAGES
    1. Comparable transplant outcomes between local and shipped deceased-donor kidneys in Australia: Analysis of Australia and New Zealand Dialysis and Transplant Registry 1992–2007 (pages 124–132)

      WAI H LIM, GRAEME R RUSS and STEPHEN P MCDONALD

      Version of Record online: 31 AUG 2009 | DOI: 10.1111/j.1440-1797.2009.01199.x

      Shipped allografts in Australia had similar transplant outcomes when compared to locally-transplanted grafts (unrelated to the degree of HLA-matching). This contrasts with data from other international centres which has demonstrated an increased risk of graft failure in shipped grafts.

  11. INSTRUCTIVE CASES/IMAGES

    1. Top of page
    2. REVIEW ARTICLE
    3. CLINICAL RESEARCH FOR NEPHROLOGISTS
    4. EDITORIAL
    5. DIALYSIS
    6. EVIDENCE-BASED NEPHROLOGY
    7. INTEGRATIVE BIOLOGY
    8. NEPHROLOGY IN HIGH RISK POPULATIONS
    9. PATHOLOGY, IMMUNOLOGY AND INFLAMMATION
    10. PROGRESSIVE CHRONIC RENAL DISEASE
    11. TRANSPLANTATION
    12. INSTRUCTIVE CASES/IMAGES
    1. CONGENITAL MALFORMATIONS WITH LOW-DOSE MYCOPHENOLATE MOFETIL AFTER KIDNEY TRANSPLANTATION (pages 133–135)

      ANOOP N KOSHY, DAVID STRONG, GAVIN EARLES and ROBERT G FASSETT

      Version of Record online: 11 FEB 2010 | DOI: 10.1111/j.1440-1797.2009.01153.x

    2. BROKEN TENCKHOFF CATHETER ON KIDNEY, URETER, BLADDER X-RAY (page 136)

      JU-KUANG CHANG, CHIU-CHING HUANG, HUEY-LIANG KUO, YA-FEI YANG and HSIN-HUNG LIN

      Version of Record online: 11 FEB 2010 | DOI: 10.1111/j.1440-1797.2009.01158.x

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