Investigation of skeletal muscle quantity and quality in end-stage renal disease (pages 454–463)
BIRINDER CHEEMA, HAIFA ABAS, BENJAMIN SMITH, ANTHONY J O'SULLIVAN, MARIA CHAN, ADITI PATWARDHAN, JOHN KELLY, ADRIAN GILLIN, GLEN PANG, BRAD LLOYD, KLAUS BERGER, BERNHARD T BAUNE and MARIA FIATARONE SINGH
Article first published online: 2 DEC 2009 | DOI: 10.1111/j.1440-1797.2009.01261.x
Advancing age, inflammation and poor nutritional status are factors contributing to the loss of muscle quality and quantity in dialysis patients. Significant functional impairments result, with elevated intramuscular lipid most closely related to poorer submaximal performance such as walking, and lower muscle CSA most closely related to maximal strength deficits.