Accumulation of circulating advanced oxidation protein products is an independent risk factor for ischaemic heart disease in maintenance haemodialysis patients (pages 642–649)
QIUGEN ZHOU, SHENGJIE WU, JIANPING JIANG, JIANWEI TIAN, JIANGHUA CHEN, XUEQING YU, PINGYAN CHEN, CHANGLIN MEI, FEI XIONG, WEI SHI, WEI ZHOU, XUSHENG LIU, SHIREN SUN, DI XIE, JUN LIU, XIN XU, MIN LIANG and FANFAN HOU
Article first published online: 26 AUG 2012 | DOI: 10.1111/j.1440-1797.2012.01640.x
These investigators examined the serum levels of advanced oxidation protein products (AOPP) in patients on haemodialysis (HD) or continuous ambulatory peritoneal dialysis (CAPD) in a cross-section study and tested AOPP as an independent risk factor for cardiovascular disease. The levels of AOPP were significantly elevated in both HD and CAPD patients compared to healthy controls. However, accumulation of AOPP was more significant in HD compared to CAPD patients. Only in HD patients, the AOPP levels exhibit an association with ischaemic heart disease.