Nephrology

Cover image for Vol. 18 Issue 1

January 2013

Volume 18, Issue 1

Pages 1–79

  1. REVIEW ARTICLES

    1. Top of page
    2. REVIEW ARTICLES
    3. DIALYSIS
    4. GENERAL NEPHROLOGY
    5. INTEGRATIVE BIOLOGY
    6. TRANSPLANTATION
    7. COCHRANE COMMENTARIES
    8. CORRESPONDENCE
    9. CORRIGENDUM
    1. You have free access to this content
      Exosomes and the kidney: Blaming the messenger (pages 1–10)

      Doreen YP Fang, Hamish W King, Jordan YZ Li and Jonathan M Gleadle

      Article first published online: 17 DEC 2012 | DOI: 10.1111/nep.12005

      Enormous interest has focused on exosomes, the small membrane-bound vesicles released into the extracellular environment by many cell types, since the realization that they play important functional roles across many aspects of cell biology and the potential to use their unique protein and RNA content as signatures in biomarker research.

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      Role of asymmetrical dimethylarginine in the progression of renal disease (pages 11–21)

      Vasileios Raptis, Stergios Kapoulas and Dimitrios Grekas

      Article first published online: 17 DEC 2012 | DOI: 10.1111/j.1440-1797.2012.01659.x

      Raptis V and colleagues provide an in-depth review on the pathomechanism of the role of ADMA in the progression of chronic kidney disease. They summarize evidence from animal and human studies showing that ADMA is in fact likely to be more than just a marker of progression and assert that intracellular levels of ADMA, generally much higher than plasma levels, potentially mediate kidney progression initiated by other factors such as high blood pressure, dyslipidemia and hyperglycaemia. From this perspective, targeted therapy to reduce ADMA levels including inhibitors of DDAH, or blocking the transporter protein related to intracellular entry of arginine for production of ADMA could potentially retard CKD progression.

  2. DIALYSIS

    1. Top of page
    2. REVIEW ARTICLES
    3. DIALYSIS
    4. GENERAL NEPHROLOGY
    5. INTEGRATIVE BIOLOGY
    6. TRANSPLANTATION
    7. COCHRANE COMMENTARIES
    8. CORRESPONDENCE
    9. CORRIGENDUM
    1. Fistula use after concurrent arteriovenous fistula formation and Tenckhoff catheter insertion (pages 22–25)

      Simon H Jiang, Patrick G Lan, James Yeung and Martin Gallagher

      Article first published online: 17 DEC 2012 | DOI: 10.1111/j.1440-1797.2012.01658.x

  3. GENERAL NEPHROLOGY

    1. Top of page
    2. REVIEW ARTICLES
    3. DIALYSIS
    4. GENERAL NEPHROLOGY
    5. INTEGRATIVE BIOLOGY
    6. TRANSPLANTATION
    7. COCHRANE COMMENTARIES
    8. CORRESPONDENCE
    9. CORRIGENDUM
    1. Vitamin D does not improve the metabolic health of patients with chronic kidney disease stage 3–4: A randomized controlled trial (pages 26–35)

      William G Petchey, Ingrid J Hickman, Johannes B Prins, Carmel M Hawley, David W Johnson and Nicole M Isbel

      Article first published online: 17 DEC 2012 | DOI: 10.1111/j.1440-1797.2012.01662.x

      Vitamin D supplementation did not reduce insulin resistance or decrease inflammation in people with stage 3–4 chronic kidney disease. Although a small study with only 25% of participants vitamin D-insufficient at baseline, this study is the first randomized controlled trial to assess this effect in chronic kidney disease and importantly raised the vitamin D concentrations to supra-sufficient levels still without positive effect.

    2. Safety and feasibility of outpatient percutaneous native kidney biopsy in the developing world: Experience in a large tertiary care centre in Eastern India (pages 36–40)

      Vishal Golay, Dipankar Sarkar, Punnoose Thomas, Mayuri Trivedi, Ametashver Singh, Arpita Roychowdhary, Sanjay Dasgupta and Rajendra Pandey

      Article first published online: 17 DEC 2012 | DOI: 10.1111/j.1440-1797.2012.01663.x

      Golay and colleagues reported a prospective observational study on outpatients with percutaneous renal biopsies. They compared the efficacy and safety of percutaneous renal biopsies in outpatients and overnight inpatients and suggested percutaneous renal biopsies could be safely performed in outpatients with low risks.

    3. Renal services disaster planning: Lessons learnt from the 2011 Queensland floods and North Queensland cyclone experiences (pages 41–46)

      David W Johnson, Bronwyn Hayes, Nicholas A Gray, Carmel Hawley, Janet Hole and Murty Mantha

      Article first published online: 17 DEC 2012 | DOI: 10.1111/nep.12008

  4. INTEGRATIVE BIOLOGY

    1. Top of page
    2. REVIEW ARTICLES
    3. DIALYSIS
    4. GENERAL NEPHROLOGY
    5. INTEGRATIVE BIOLOGY
    6. TRANSPLANTATION
    7. COCHRANE COMMENTARIES
    8. CORRESPONDENCE
    9. CORRIGENDUM
    1. Targeting the AGE-RAGE axis improves renal function in the context of a healthy diet low in advanced glycation end-product content (pages 47–56)

      Vicki Thallas-Bonke, Melinda T Coughlan, Adeline LY Tan, Brooke E Harcourt, Philip E Morgan, Michael J Davies, Leon A Bach, Mark E Cooper and Josephine M Forbes

      Article first published online: 17 DEC 2012 | DOI: 10.1111/j.1440-1797.2012.01665.x

      Low-AGE diet does not attenuate experimental diabetic nephropathy.

  5. TRANSPLANTATION

    1. Top of page
    2. REVIEW ARTICLES
    3. DIALYSIS
    4. GENERAL NEPHROLOGY
    5. INTEGRATIVE BIOLOGY
    6. TRANSPLANTATION
    7. COCHRANE COMMENTARIES
    8. CORRESPONDENCE
    9. CORRIGENDUM
    1. Conversion to enteric-coated mycophenolate sodium from mycophenolate mofetil in stable renal transplant patients: Results of an Asia–Pacific study (pages 57–62)

      Po-Huang Lee, Anantharaman Vathsala, Duck Jong Han, Tak-Mao Chan, Hin-Seng Wong, Chad Woodcock, Nicol Kurstjens, on behalf of the Asia Pacific MyPROMS Study Investigators, Pary Sivaraman, Sheng-Hsien Chu, Hwei-Ho Hsieh, Kuo-Hsiung Hsu, Po-Chang Lee, Jong-Da Lian, Wu-Chang Yang, Zaki Morad, Si-Yen Tan, Duck Jong Han, Ki Il Park, Yui-Pong Siu and Wai Kay Tsang

      Article first published online: 17 DEC 2012 | DOI: 10.1111/nep.12007

      This study enrolled 112 patients from 16 Asian centres in Asian countries demonstrating that enteric-coated mycophenolate sodium is a safe and effective alternative to mycophenolate mofetil. The incidence of gastrointestinal upset was reduced.

    2. Enteric-coated mycophenolate sodium in combination with full dose or reduced dose cyclosporine, basiliximab and corticosteroids in Australian de novo kidney transplant patients (pages 63–70)

      Steve Chadban, Josette Eris, Graeme Russ, Scott Campbell, Jeremy Chapman, Bruce Pussell, Paul Trevillian, Francesco Ierino, Napier Thomson, Brian Hutchison, Ashley Irish, Chad Woodcock, Nicol Kurstjens, Rowan Walker and : the MyProms AU01 Study Group

      Article first published online: 17 DEC 2012 | DOI: 10.1111/nep.12004

      This RCT examined whether enteric-coated mycophenolate sodium would enable use of CsA dosed to reduced C2 targets. There was no significant difference in creatinine clearance, AR, graft loss or death for usual versus reduced exposure CsA suggesting de novo renal transplant patients can safely receive a regimen of either full or reduced exposure CsA with EC-MPS, corticosteroids and basiliximab.

  6. COCHRANE COMMENTARIES

    1. Top of page
    2. REVIEW ARTICLES
    3. DIALYSIS
    4. GENERAL NEPHROLOGY
    5. INTEGRATIVE BIOLOGY
    6. TRANSPLANTATION
    7. COCHRANE COMMENTARIES
    8. CORRESPONDENCE
    9. CORRIGENDUM
    1. You have free access to this content
  7. CORRESPONDENCE

    1. Top of page
    2. REVIEW ARTICLES
    3. DIALYSIS
    4. GENERAL NEPHROLOGY
    5. INTEGRATIVE BIOLOGY
    6. TRANSPLANTATION
    7. COCHRANE COMMENTARIES
    8. CORRESPONDENCE
    9. CORRIGENDUM
    1. Acute Kidney Injury after a Pelvic Surgery (pages 73–74)

      Mototsugu Tanaka, Junichi Hirahashi, Takamoto Ohse and Toshiro Fujita

      Article first published online: 17 DEC 2012 | DOI: 10.1111/j.1440-1797.2012.01609.x

    2. Successful Treatment of Pulmonary Rhizopus Infection with Surgical Resection and Posaconazole in a Renal Transplant Recipient (pages 74–75)

      Lorraine PY Kwan, Cindy BY Choy, Tak Mao Chan, Wai Sing Suen and Desmond YH Yap

      Article first published online: 17 DEC 2012 | DOI: 10.1111/j.1440-1797.2012.01616.x

    3. F18-Fluordesoxyglucose Positron Emission Tomography-Computed Tomography of the Kidney after Calculus Passage (pages 75–76)

      Michael Quentin, Hubertus Hautzel, Christian Arsov and Axel Scherer

      Article first published online: 17 DEC 2012 | DOI: 10.1111/j.1440-1797.2012.01614.x

    4. Persistent Immature Glomeruli in a Girl with Refractory Nephrotic Syndrome (pages 77–78)

      Taichiro Nakamura, Kazushi Tsuruga, Shojiro Watanabe, Etsuro Ito, Kensuke Joh and Hiroshi Tanaka

      Article first published online: 17 DEC 2012 | DOI: 10.1111/j.1440-1797.2012.01617.x

  8. CORRIGENDUM

    1. Top of page
    2. REVIEW ARTICLES
    3. DIALYSIS
    4. GENERAL NEPHROLOGY
    5. INTEGRATIVE BIOLOGY
    6. TRANSPLANTATION
    7. COCHRANE COMMENTARIES
    8. CORRESPONDENCE
    9. CORRIGENDUM
    1. You have free access to this content

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