Nephrology

Cover image for Vol. 18 Issue 2

February 2013

Volume 18, Issue 2

Pages 81–159

  1. REVIEW ARTICLE

    1. Top of page
    2. REVIEW ARTICLE
    3. ACUTE RENAL DISEASE
    4. DIALYSIS
    5. GENERAL NEPHROLOGY
    6. PATHOLOGY, IMMUNOLOGY & INFLAMMATION
    7. HYPERTENSION
    8. PROGRESSIVE CHRONIC RENAL DISEASE
    9. PERITONEAL DIALYSIS
    10. TRANSPLANTATION
    11. CORRESPONDENCE
    1. You have free access to this content
      Mononuclear phagocyte system in kidney disease and repair (pages 81–91)

      Maliha A Alikhan and Sharon D Ricardo

      Article first published online: 20 JAN 2013 | DOI: 10.1111/nep.12014

      This manuscript provides a comprehensive overview of the monocyte–macrophage–dendritic cell system in renal disease.

  2. ACUTE RENAL DISEASE

    1. Top of page
    2. REVIEW ARTICLE
    3. ACUTE RENAL DISEASE
    4. DIALYSIS
    5. GENERAL NEPHROLOGY
    6. PATHOLOGY, IMMUNOLOGY & INFLAMMATION
    7. HYPERTENSION
    8. PROGRESSIVE CHRONIC RENAL DISEASE
    9. PERITONEAL DIALYSIS
    10. TRANSPLANTATION
    11. CORRESPONDENCE
    1. Renal impairment among acute hospital admissions in a rural Ethiopian hospital (pages 92–96)

      Stephen Riley, Ermias Diro, Peter Batchelor, Alula Abebe, Ashenafi Amsalu, Yewondwossen Tadesse, John Williams and Aled O Phillips

      Article first published online: 20 JAN 2013 | DOI: 10.1111/nep.12002

      This paper describes the spectrum of acute kidney injury (AKI) in a general hospital in rural Ethiopia. Most patients were young, had pre-renal AKI, and the mortality was no different from those with no AKI. Despite limitations, the study brings out differences with AKI seen in developed World.

  3. DIALYSIS

    1. Top of page
    2. REVIEW ARTICLE
    3. ACUTE RENAL DISEASE
    4. DIALYSIS
    5. GENERAL NEPHROLOGY
    6. PATHOLOGY, IMMUNOLOGY & INFLAMMATION
    7. HYPERTENSION
    8. PROGRESSIVE CHRONIC RENAL DISEASE
    9. PERITONEAL DIALYSIS
    10. TRANSPLANTATION
    11. CORRESPONDENCE
    1. Prevalence of gastrointestinal and psychosomatic symptoms among Asian patients undergoing regular hemodialysis (pages 97–103)

      Vui Heng Chong and Jackson Tan

      Article first published online: 20 JAN 2013 | DOI: 10.1111/nep.12000

      The authors investigated 123 hemodialysis patients (male 47.2%) and found that 70.7% of them had experienced some GI symptoms, significantly more than controls (P < 0.05). These patients had more anorexia, nausea, vomiting, dyspepsia, irregular bowel habit and bleeding per rectum (all P < 0.05). The authors concluded that GI and psychosomatic symptoms are common among hemodialysis patients.

  4. GENERAL NEPHROLOGY

    1. Top of page
    2. REVIEW ARTICLE
    3. ACUTE RENAL DISEASE
    4. DIALYSIS
    5. GENERAL NEPHROLOGY
    6. PATHOLOGY, IMMUNOLOGY & INFLAMMATION
    7. HYPERTENSION
    8. PROGRESSIVE CHRONIC RENAL DISEASE
    9. PERITONEAL DIALYSIS
    10. TRANSPLANTATION
    11. CORRESPONDENCE
    1. Mycophenolate mofetil versus azathioprine as maintenance therapy for lupus nephritis: A meta-analysis (pages 104–110)

      Li Feng, Jin Deng, Dong-Mei Huo, Qiao-Yuan Wu and Yun-Hua Liao

      Article first published online: 20 JAN 2013 | DOI: 10.1111/nep.12006

      The authors conducted a meta-analysis of randomized controlled trials assessing the prognosis and safety of mycophenolate mofetil (MMF) versus azathioprine (AZA) used as maintenance therapy for lupus nephritis. Although the evidence was limited, they did derive a conclusion that MMF was as useful, or safer than AZA for maintenance therapy of lupus nephritis.

  5. PATHOLOGY, IMMUNOLOGY & INFLAMMATION

    1. Top of page
    2. REVIEW ARTICLE
    3. ACUTE RENAL DISEASE
    4. DIALYSIS
    5. GENERAL NEPHROLOGY
    6. PATHOLOGY, IMMUNOLOGY & INFLAMMATION
    7. HYPERTENSION
    8. PROGRESSIVE CHRONIC RENAL DISEASE
    9. PERITONEAL DIALYSIS
    10. TRANSPLANTATION
    11. CORRESPONDENCE
    1. Uremic anorexia and gastrointestinal motility dysfunction correlate with the changes of ghrelin system in hypothalamus (pages 111–116)

      Rong-Guo Fu, Heng Ge, Gang-Lian Yao, Li Wang, Shu-Ting Ren, Li-Qun Ma, Bao-Song Gui, Zhao Chen, Dan Zhu and Rong-Liang Xue

      Article first published online: 20 JAN 2013 | DOI: 10.1111/nep.12015

      This study demonstrates that anorexia and gastrointestinal motility dysfunction in rats with chronic renal failure are correlated with the reduction of hypothalamic ghrelin and growth hormone secretagogue receptor.

  6. HYPERTENSION

    1. Top of page
    2. REVIEW ARTICLE
    3. ACUTE RENAL DISEASE
    4. DIALYSIS
    5. GENERAL NEPHROLOGY
    6. PATHOLOGY, IMMUNOLOGY & INFLAMMATION
    7. HYPERTENSION
    8. PROGRESSIVE CHRONIC RENAL DISEASE
    9. PERITONEAL DIALYSIS
    10. TRANSPLANTATION
    11. CORRESPONDENCE
    1. You have free access to this content
      Complexity reduction of chromatin architecture in macula densa cells during mouse postnatal development (pages 117–124)

      Igor Pantic, Gordana Basta-Jovanovic, Vesna Starcevic, Jovana Paunovic, Slavica Suzic, Zvezdana Kojic and Senka Pantic

      Article first published online: 20 JAN 2013 | DOI: 10.1111/nep.12003

      An observation study in mice suggesting that the chromatin of macula densa cells undergoes loss of structural complexity that is most pronounced immediately after birth and remains during the first month of postnatal life. The findings add to the knowledge about the changes that take place in the kidney during postnatal development function and tissue structural organization, which are linked to changes in physiological function.

  7. PROGRESSIVE CHRONIC RENAL DISEASE

    1. Top of page
    2. REVIEW ARTICLE
    3. ACUTE RENAL DISEASE
    4. DIALYSIS
    5. GENERAL NEPHROLOGY
    6. PATHOLOGY, IMMUNOLOGY & INFLAMMATION
    7. HYPERTENSION
    8. PROGRESSIVE CHRONIC RENAL DISEASE
    9. PERITONEAL DIALYSIS
    10. TRANSPLANTATION
    11. CORRESPONDENCE
    1. Serum immunoglobulin A/C3 ratio predicts progression of immunoglobulin A nephropathy (pages 125–131)

      Jun Zhang, Cheng Wang, Ying Tang, Hui Peng, Zeng-chun Ye, Cui-cui Li and Tan-Qi Lou

      Article first published online: 20 JAN 2013 | DOI: 10.1111/nep.12010

      The authors have examined whether the suggested novel marker, IgA/C3 ratio, is valid to predict the prognosis of IgAN in this patient population with IgAN.

  8. PERITONEAL DIALYSIS

    1. Top of page
    2. REVIEW ARTICLE
    3. ACUTE RENAL DISEASE
    4. DIALYSIS
    5. GENERAL NEPHROLOGY
    6. PATHOLOGY, IMMUNOLOGY & INFLAMMATION
    7. HYPERTENSION
    8. PROGRESSIVE CHRONIC RENAL DISEASE
    9. PERITONEAL DIALYSIS
    10. TRANSPLANTATION
    11. CORRESPONDENCE
    1. Characteristics and clinical outcomes of hyponatraemia in peritoneal dialysis patients (pages 132–137)

      Seok Hui Kang, Kyu Hyang Cho, Jong Won Park, Kyung Woo Yoon and Jun Young Do

      Article first published online: 20 JAN 2013 | DOI: 10.1111/nep.12013

      This manuscript analyzes the incidence of hyponatraemia in 387 Korean peritoneal dialysis patients and determines their fluid status with simultaneous bioelectrical impedance analysis measurement. The results demonstrate low residual renal function and long duration of peritoneal dialysis were associated with development of hyponatraemia by appropriate water gain. In addition the prevalence of hyponatraemia increases along with the increased comorbidity status. On multivariate analysis, age, hypoalbuminaemia, low residual renal function and increasing comorbidities were associated with higher mortality in this peritoneal dialysis population.

    2. Smad7 gene transfer attenuates angiogenesis in peritoneal dialysis rats (pages 138–147)

      Weisheng Peng, Xianrui Dou, Wenke Hao, Qiaoling Zhou, Rong Tang, Jing Nie, Hui Y Lan and Xueqing Yu

      Article first published online: 20 JAN 2013 | DOI: 10.1111/nep.12017

      This is an animal study that demonstrated reduced peritoneal angiogenesis through the blockade of transforming growth factor-β, through signalling with Smad7. This presents a novel therapeutic approach to decrease ultrafiltration failure and hence increase peritoneal dialysis technique longevity.

  9. TRANSPLANTATION

    1. Top of page
    2. REVIEW ARTICLE
    3. ACUTE RENAL DISEASE
    4. DIALYSIS
    5. GENERAL NEPHROLOGY
    6. PATHOLOGY, IMMUNOLOGY & INFLAMMATION
    7. HYPERTENSION
    8. PROGRESSIVE CHRONIC RENAL DISEASE
    9. PERITONEAL DIALYSIS
    10. TRANSPLANTATION
    11. CORRESPONDENCE
    1. Haemoglobin variability in the early post-transplant period: Association with graft survival and mortality (pages 148–156)

      Benaya Rozen-Zvi, Binjamin Ben-Avraham, Shira Schneider, Anat Gafter-Gvili, Rachel S Levy-Drummer, Boris Zingerman, Eitan Mor, Uzi Gafter and Ruth Rahamimov

      Article first published online: 20 JAN 2013 | DOI: 10.1111/nep.12009

      This study demonstrates that high haemoglobin variability in the first 6 months post-transplant is independently associated with inferior graft survival in patients after kidney transplantation. While no inference on the effect of haemoglobin variability on outcomes can be made, the association is very interesting and warrants further consideration.

  10. CORRESPONDENCE

    1. Top of page
    2. REVIEW ARTICLE
    3. ACUTE RENAL DISEASE
    4. DIALYSIS
    5. GENERAL NEPHROLOGY
    6. PATHOLOGY, IMMUNOLOGY & INFLAMMATION
    7. HYPERTENSION
    8. PROGRESSIVE CHRONIC RENAL DISEASE
    9. PERITONEAL DIALYSIS
    10. TRANSPLANTATION
    11. CORRESPONDENCE
    1. Invasive candidiasis complicating renal transplantation (page 157)

      Ranga Migara Weerakkody, Deepal Sanjaya Heiyantuduwa and Mohamed Hussain Rezvi Sheriff

      Article first published online: 20 JAN 2013 | DOI: 10.1111/j.1440-1797.2012.01623.x

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