Nephrology

Cover image for Vol. 18 Issue 8

August 2013

Volume 18, Issue 8

Pages 533–583

  1. DIALYSIS

    1. Top of page
    2. DIALYSIS
    3. PERITONEAL DIALYSIS
    4. INTEGRATIVE BIOLOGY
    5. PATHOLOGY, IMMUNOLOGY AND INFLAMMATION
    6. DIABETES
    7. REGISTRIES/RENAL EPIDEMIOLOGY
    8. COCHRANE COMMENTARIES
    9. CORRESPONDENCE
    1. Dosing regimen and tolerability of methoxy polyethylene glycol–epoetin beta in Chinese dialysis patients (pages 533–538)

      Bo Ying Choy, Man Fai Lam, Terence Yip, Hon Lok Tang, Ping Nam Wong, Chik Cheung Vincent Chow, Desmond YH Yap and Tak Mao Chan

      Version of Record online: 18 JUL 2013 | DOI: 10.1111/nep.12105

      Summary at a Glance

      This two-part open label study establishes: (i) a safe effective initiating regime for methyl polyethylene glycol epoetin beta in ESA-naive Chinese dialysis patients; and (ii) an effective regime for dose conversion from darbepoetin alpha to methyl polyethylene glycol epoetin beta in Chinese dialysis patients.

  2. PERITONEAL DIALYSIS

    1. Top of page
    2. DIALYSIS
    3. PERITONEAL DIALYSIS
    4. INTEGRATIVE BIOLOGY
    5. PATHOLOGY, IMMUNOLOGY AND INFLAMMATION
    6. DIABETES
    7. REGISTRIES/RENAL EPIDEMIOLOGY
    8. COCHRANE COMMENTARIES
    9. CORRESPONDENCE
    1. Inflammatory factors for hypoalbuminemia in Japanese peritoneal dialysis patients (pages 539–544)

      Masuyo Shioya, Takuya Yoshida, Kenji Kasai, Ryuichi Furuya, Akihiko Kato, Noriko Mori, Yoshihiro Matsumoto and Hiromichi Kumagai

      Version of Record online: 18 JUL 2013 | DOI: 10.1111/nep.12106

      Summary at a Glance

      This cross-sectional study of 76 Japanese PD patients demonstrated that hypoalbuminaemia is correlated with systemic and local peritoneal inflammation as measured by IL-6, and high transport status. They also noted that CA125, traditionally used as a marker of mesothelial cell mass, correlated positively with high transport status, but not with inflammation. This study suggests that the low serum albumin seen in many PD patients may be due to both peritoneal and systemic inflammation.

    2. Treatment failure in automated peritoneal dialysis and double-bag continuous ambulatory peritoneal dialysis (pages 545–548)

      Pisut Katavetin, Yuwadee Theerasin, Worapot Treamtrakanpon, Nalinee Saiprasertkit and Talerngsak Kanjanabuch

      Version of Record online: 18 JUL 2013 | DOI: 10.1111/nep.12107

      Summary at a Glance

      This study looks at the outcome of patient on APD versus CAPD at a single centre in Thailand. While this is a small retrospective study in a single centre, it is the only data on APD coming out of a country with a huge PD population from a PD first policy. Results of this study are important for policy crafting in Thailand.

  3. INTEGRATIVE BIOLOGY

    1. Top of page
    2. DIALYSIS
    3. PERITONEAL DIALYSIS
    4. INTEGRATIVE BIOLOGY
    5. PATHOLOGY, IMMUNOLOGY AND INFLAMMATION
    6. DIABETES
    7. REGISTRIES/RENAL EPIDEMIOLOGY
    8. COCHRANE COMMENTARIES
    9. CORRESPONDENCE
    1. Clinical and pathologic characteristics of hereditary apolipoprotein A-I amyloidosis in Ireland (pages 549–554)

      Carol A Traynor, Donal Tighe, Frank J O'Brien, Sean F Leavey, Anthony M Dorman, Mark D Denton, Colm Magee and Peter J Conlon

      Version of Record online: 18 JUL 2013 | DOI: 10.1111/nep.12108

      Summary at a glance

      This is an interesting case series which described the clinical features of hereditary amyloidosis due to apolipoprotein A-I deficiency. It will improve the awareness of this rare kind of hereditary amyloidosis.

  4. PATHOLOGY, IMMUNOLOGY AND INFLAMMATION

    1. Top of page
    2. DIALYSIS
    3. PERITONEAL DIALYSIS
    4. INTEGRATIVE BIOLOGY
    5. PATHOLOGY, IMMUNOLOGY AND INFLAMMATION
    6. DIABETES
    7. REGISTRIES/RENAL EPIDEMIOLOGY
    8. COCHRANE COMMENTARIES
    9. CORRESPONDENCE
    1. Altered diurnal variation and localization of clock proteins in the remnant kidney of 5/6 nephrectomy rats (pages 555–562)

      Xiao-mei Huang, Wen-li Chen, Jing-ping Yuan, Yue-hong Yang, Qi-hui Mei and Li-xia Huang

      Version of Record online: 18 JUL 2013 | DOI: 10.1111/nep.12111

      Summary at a Glance

      Circadian clocks that are important in maintaining renal function are regulated by the interplay of transcription factors. Huang et al. have reported an altered distribution and localization of three clock proteins, BMAL1, PER2 and DBP in a 5/6 nephrectomy model in rats, compared to controls. The study demonstrates that these clock proteins are associated with kidney diurnal rhythm and abnormal gene and protein expression evident with circadian fluctuations was associated with loss of renal function.

  5. DIABETES

    1. Top of page
    2. DIALYSIS
    3. PERITONEAL DIALYSIS
    4. INTEGRATIVE BIOLOGY
    5. PATHOLOGY, IMMUNOLOGY AND INFLAMMATION
    6. DIABETES
    7. REGISTRIES/RENAL EPIDEMIOLOGY
    8. COCHRANE COMMENTARIES
    9. CORRESPONDENCE
    1. Clinical significance of microscopic haematuria in diabetic nephropathy in type 2 diabetes patients with overt proteinuria (pages 563–568)

      Tomonari Okada, Toshitaka Nagao, Hiroshi Matsumoto, Yume Nagaoka, Toshikazu Wada and Toshiyuki Nakao

      Version of Record online: 18 JUL 2013 | DOI: 10.1111/nep.12104

      Summary at a Glance

      This paper details a biopsy-based clinical outcomes analysis of the significance of persistent microscopic haematuria in patients with diabetic nephropathy. Of interest is its unique contribution to the literature of a common but poorly understood clinical finding.

  6. REGISTRIES/RENAL EPIDEMIOLOGY

    1. Top of page
    2. DIALYSIS
    3. PERITONEAL DIALYSIS
    4. INTEGRATIVE BIOLOGY
    5. PATHOLOGY, IMMUNOLOGY AND INFLAMMATION
    6. DIABETES
    7. REGISTRIES/RENAL EPIDEMIOLOGY
    8. COCHRANE COMMENTARIES
    9. CORRESPONDENCE
    1. Prevalence and risk factors for proteinuria: The National Kidney Foundation of Malaysia Lifecheck Health Screening programme (pages 569–575)

      Loke Meng Ong, Narayanan Punithavathi, Dharminy Thurairatnam, Hadzlinda Zainal, Mei Li Beh, Zaki Morad, Sharleen YS Lee, Sunita Bavanandan and Lai Sun Kok

      Version of Record online: 18 JUL 2013 | DOI: 10.1111/nep.12112

      This is an important screening study in a large multi-ethnic Asian country, which further extends our understanding of the prevalence of renal disease in different populations. The frequencies of albuminuria, hypertension and diabetes in patients previously unaware of their disease serves to focus on the need for screening and again raises the question of whether this should be targeted or non-selective.

  7. COCHRANE COMMENTARIES

    1. Top of page
    2. DIALYSIS
    3. PERITONEAL DIALYSIS
    4. INTEGRATIVE BIOLOGY
    5. PATHOLOGY, IMMUNOLOGY AND INFLAMMATION
    6. DIABETES
    7. REGISTRIES/RENAL EPIDEMIOLOGY
    8. COCHRANE COMMENTARIES
    9. CORRESPONDENCE
  8. CORRESPONDENCE

    1. Top of page
    2. DIALYSIS
    3. PERITONEAL DIALYSIS
    4. INTEGRATIVE BIOLOGY
    5. PATHOLOGY, IMMUNOLOGY AND INFLAMMATION
    6. DIABETES
    7. REGISTRIES/RENAL EPIDEMIOLOGY
    8. COCHRANE COMMENTARIES
    9. CORRESPONDENCE

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