Nephrology

Cover image for Vol. 21 Issue 8

August 2016

Volume 21, Issue 8

Pages 635–723

  1. Issue Information

    1. Top of page
    2. Issue Information
    3. Review Articles
    4. Original Articles
    5. Brief Communication
    6. Correspondence
    1. You have free access to this content
      Issue Information (pages 635–637)

      Version of Record online: 19 JUL 2016 | DOI: 10.1111/nep.12603

  2. Review Articles

    1. Top of page
    2. Issue Information
    3. Review Articles
    4. Original Articles
    5. Brief Communication
    6. Correspondence
    1. DIALYSIS

      You have free access to this content
      Depression in dialysis patients (pages 639–646)

      Terry King-Wing Ma and Philip Kam-Tao Li

      Version of Record online: 19 JUL 2016 | DOI: 10.1111/nep.12742

      Summary at a Glance

      This review examines some current features of the diagnosis and management of depression in dialysis patients. The overlapping symptoms of kidney failure managed with dialysis and depression and their interpretation are highlighted. The evidence and rationale for treatment are discussed.

    2. TRANSPLANTATION

      You have free access to this content
      BK virus nephropathy in renal transplant recipients (pages 647–654)

      Jagadish S Jamboti

      Version of Record online: 19 JUL 2016 | DOI: 10.1111/nep.12728

      Summary at a Glance

      A brief update on the prevention, detection and management of BK nephropathy in renal transplant recipients

    3. HYPERTENSION

      You have free access to this content
      Risk of bradykinin B2 receptor -58T/C gene polymorphism on hypertension: A meta-analysis (pages 655–662)

      Kaiping Luo, Pingping Yang and Gaosi Xu

      Version of Record online: 19 JUL 2016 | DOI: 10.1111/nep.12782

      Summary at a Glance

      A meta-analysis of 13 studies reporting the association between d -58C allele and -58CC genotype and increased odds of hypertension in Asians and African-Americans.

  3. Original Articles

    1. Top of page
    2. Issue Information
    3. Review Articles
    4. Original Articles
    5. Brief Communication
    6. Correspondence
    1. DIALYSIS

      Arterial line versus venous line administration of low molecular weight heparin, enoxaparin for prevention of thrombosis in the extracorporeal blood circuit of patients on haemodialysis or haemodiafiltration: A randomized cross-over trial (pages 663–668)

      Jagadeesh Kurtkoti, Bhadran Bose, Balaji Hiremagalur, Jing Sun and Tara Cochrane

      Version of Record online: 19 JUL 2016 | DOI: 10.1111/nep.12681

      SUMMARY AT A GLANCE

      Low molecular weight heparins (LMWH) are frequency used to prevent thrombosis in the haemodialysis circuit. This is the first study showing that the dose of enoxaparin, an LMWH needs to be 25–50% lower if administered via the venous line as compared with the arterial line in patients on haemodialysis.

    2. Cost-effectiveness of haemodialysis and peritoneal dialysis for patients with end-stage renal disease in Singapore (pages 669–677)

      Fan Yang, Titus Lau and Nan Luo

      Version of Record online: 19 JUL 2016 | DOI: 10.1111/nep.12668

      SUMMARY AT A GLANCE

      This study uses a sophisticated Markov modelling strategy to estimate cost-effectiveness of CAPD, APD and HD over a 10 year time frame using a “societal” perspective. In Singapore, HD is the dominant method of dialysis yet this study suggests the cost-effectiveness of CAPD is superior and may assist in planning for the incremental demand of ESRD in Singapore.

    3. GENERAL NEPHROLOGY

      Effects of glomerular filtration rate estimating equations derived from different reference methods on staging and long term mortality risks of chronic kidney disease in a Southeast Asian cohort (pages 678–686)

      Sukit Yamwong, Chagriya Kitiyakara, Prin Vathesatogkit, Krittika Saranburut, Anchalee Chittamma, Sayan Cheepudomwit, Somlak Vanavanan, Tawatchai Akrawichien and Piyamitr Sritara

      Version of Record online: 19 JUL 2016 | DOI: 10.1111/nep.12660

      Summary at a Glance

      In a cohort of Thai workers, the authors compared estimated GFR from several GFR estimation equations and found significant differences. Equations developed using inulin as a reference method produced lower GFR estimates than those developed using DTPA. Further work is needed to identify the best eGFR equations for Asian populations.

    4. Simple renal cyst and renal dysfunction: A pilot study using dimercaptosuccinic acid renal Scan (pages 687–692)

      Taekmin Kwon, Bumjin Lim, Dalsan You, Bumsik Hong, Jun Hyuk Hong, Choung-Soo Kim and In Gab Jeong

      Version of Record online: 19 JUL 2016 | DOI: 10.1111/nep.12654

      Summary at a Glance

      In this case control study, the differences between split renal function were compared between 50 patients with large unilateral simple renal cyst (4 cm or above) and 50 kidney donors. DMSA renal scans showed that a significant proportion of large unilateral simple renal cysts are associated with decreased relative renal function. The effect of intervention on the renal function in this group of patients would require further study.

    5. ACUTE RENAL DISEASE

      Erythropoietin concentration in acute kidney injury is associated with insulin-like growth factor-binding protein-1 (pages 693–699)

      Tetsushi Yamashita, Eisei Noiri, Yoshifumi Hamasaki, Takehiro Matsubara, Takeshi Ishii, Naoki Yahagi, Masaomi Nangaku and Kent Doi

      Version of Record online: 19 JUL 2016 | DOI: 10.1111/nep.12656

      Summary at a Glance

      This study by Yamashita et al investigated the association of plasma EPO concentrations with plasma IGFBP-1, diabetes complications and systemic inflammation in AKI patients. They found that increased EPO concentrations in AKI patients are associated with high plasma IGFBP-1and complication of diabetes mellitus, but not IL-6. The authors addressed all the questions raised by two reviewers. The revised manuscript is generally well written and clearly presented.

    6. TRANSPLANTATION

      Bortezomib for refractory acute antibody-mediated rejection in kidney transplant recipients: A single-centre case series (pages 700–704)

      Erika De Sousa-Amorim, Ignacio Revuelta, Fritz Diekmann, Frederic Cofan, Miquel Lozano, Joan Cid, Eduard Palou, Manel Sole, Josep María Campistol and Federic Oppenheimer

      Version of Record online: 19 JUL 2016 | DOI: 10.1111/nep.12659

      SUMMARY AT A GLANCE

      This manuscript describes the use of bortezomib in seven renal transplant cases with refractory acute antibody-mediated rejection. As with most of these small retrospective uncontrolled case studies, the actual benefit of bortezomib remains unclear. Nevertheless the patient outcomes (reasonable in the medium term), and side effects experienced are useful to review. Further studies examining this therapy are still required however.

    7. PROGRESSIVE CHRONIC RENAL DISEASE

      KHA-CARI guideline recommendations for the diagnosis and management of autosomal dominant polycystic kidney disease (pages 705–716)

      Gopala K Rangan, Stephen I Alexander, Katrina L Campbell, Mark AJ Dexter, Vincent W Lee, Pamela Lopez-Vargas, Jun Mai, Andrew Mallett, Chirag Patel, Manish Patel, Michel C Tchan, Allison Tong, David J Tunnicliffe, Philip Vladica and Judy Savige

      Version of Record online: 19 JUL 2016 | DOI: 10.1111/nep.12658

      Summary at a Glance

      An important further Guideline from the CARI group in Australia - this time relating to adult polycystic kidney disease.

  4. Brief Communication

    1. Top of page
    2. Issue Information
    3. Review Articles
    4. Original Articles
    5. Brief Communication
    6. Correspondence
    1. Cardiovascular

      Reduced kidney function is a risk factor for atrial fibrillation (pages 717–720)

      Jari A Laukkanen, Francesco Zaccardi, Jouni Karppi, Kimmo Ronkainen and Sudhir Kurl

      Version of Record online: 19 JUL 2016 | DOI: 10.1111/nep.12727

  5. Correspondence

    1. Top of page
    2. Issue Information
    3. Review Articles
    4. Original Articles
    5. Brief Communication
    6. Correspondence
    1. Simultaneous adult polycystic kidney disease and Alport syndrome (pages 722–723)

      Paul J Phelan, Elaine Fletcher, Nicola Carroll, Wendy Metcalfe and A Neil Turner

      Version of Record online: 19 JUL 2016 | DOI: 10.1111/nep.12661

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