• 1
    Monnig AA, Prittie JE. A review of stress-related mucosal disease. J Vet Emerg Crit Care (San Antonio)2011; 21: 48495.
  • 2
    Tsukamoto T, Antonic V, El Hajj  II et al. Novel model of peripheral tissue trauma-induced inflammation and gastrointestinal dysmotility. Neurogastroenterol Motil2011; 23: 379-e164.
  • 3
    Lucas CE, Sugawa C, Riddle J, Rector F, Rosenberg SB, Walt AJ. Natural history and surgical dilemma of “stress” gastric bleeding. Arch Surg1971; 102: 26673.
  • 4
    Thacher M, Rivera LR, Cho HJ et al. The relationship between glial distortion and neuronal changes following intestinal ischemia and reperfusion. Neurogastroenterol Motil2011; 23: e5009.
  • 5
    Raedschelders K, Ansley DM, Chen DD. The cellular and molecular origin of reactive oxygen species generation during myocardial ischemia and reperfusion. Pharmacol Ther2012; 133: 23055.
  • 6
    Marchant DJ, Boyd JH, Lin DC, Granville DJ, Garmaroudi FS, McManus BM. Inflammation in myocardial diseases. Circ Res2012; 110: 12644.
  • 7
    Takagi T, Naito Y, Ichikawa H et al. A PPAR-gamma ligand, 15-deoxy-Delta12, 14- prostaglandin J(2), inhibited gastric mucosal injury induced byischemia-reperfusion in rats. Redox Rep2004; 9: 37681.
  • 8
    Zúñiga J, Cancino M, Medina F et al. N-3 PUFA supplementation triggers PPAR-α activation and PPAR-α/NF-κB interaction: anti-inflammatory implications in liver ischemia-reperfusion injury. PLoS ONE2011; 6: e28502.
  • 9
    Zhang JF, Zhang YM, Yan CD, Zhou XP. Neuroregulative mechanism of hypothalamic paraventricular nucleus on gastric ischemia-reperfusion injury in rats. Life Sci2002; 71: 150110.
  • 10
    Zhang YM, Wei EQ, Li L, Qiao WL, Wang L, Zhang JF. Extracellular signal-regulated kinase pathways may mediate the protective effect of electrical stimulation of the paraventricular nucleus against ischaemia-reperfusion injury of the gastric mucosa. Clin Exp Pharmacol Physiol2007; 34: 74252.
  • 11
    Xu FD, Frazier DT. Modulation of respiratory motor output by cerebellar deep nuclei in the rat. J Appl Physiol2000; 89: 9961004.
  • 12
    Milik E, Szczepanska SE, Cudnoch JA, Dobruch J. Down-regulation of V1a vasopressin receptors in the cerebellum after myocardial infarction. Neurosci Lett2011; 2: 11923.
  • 13
    Tirapu UJ, Luna LP, Lglesias MD, Hernaez GP. Cerebellar contribution to cognitive process:current advances. Rev Neurol2011; 5: 30115.
  • 14
    Galea JM, Vazquez A, Pasricha N, Dexivry JJ, Celnik P. Dissociating the roles of the cerebellum and motor cortex during adaptive learing: the motor cortex retains what the cerebellum learns. Cereb Cortex2011; 8: 176170.
  • 15
    Peng YP, Qiu YH, Qiu J, Wang JJ. Cerebellar interposed nucleus lesions suppress lymphocyte function in rats. Brain Res Bull2006; 71: 107.
  • 16
    Zago T, Pea U, Fumagalli GL, Marzorati G, Bianchi F. Cerebellar pathology and micturitional disorders: anatomotopographic and functional correlations. Arch Ital Urol Androl2010; 4: 17780.
  • 17
    Lisander B, Martner J. Effects on gastric motility from the cerebellar fastigial nucleus. Acta Physiol Scand1975; 94: 36877.
  • 18
    Çavdar S, Onat F, Aker R, Şehirli U, Şan T, Yananli HR. The afferent connections of the posterior hypothalamic nucleus in the rat using horseradish peroxidase. J Ana2001; 198: 46372.
  • 19
    Zhang YP, Ma C, Wen YQ, Wang JJ. Convergence of gastric vagal and cerebellar fastigial nuclear inputs on glycemia-sensitive neurons of lateral hypothalamic area in the rat. Neurosci Res2003; 45: 916.
  • 20
    Gao XB, Anthony N, Vanden P. GABA, not glutamate, a primary transmitter driving action potentials in developing hypothalamic neurons. J Neurophysiol2001; 85: 42534.
  • 21
    Chavas J, Marty A. Coexistence of excitatory and inhibitory GABA synapses in the cerebellar interneuron network. J Neurosci2003; 23: 201931.
  • 22
    Liu SJ, Lachamp P. The activation of excitatory glutamate receptors evokes a long-lasting increase in the release of GABA from cerebellar stellate cells. J Neurosci2006; 26: 93329.
  • 23
    Zhang YP, Zhu JN, Chen K, Li HZ, Wang JJ. Neurons in the rat lateral hypothalamic area integrate information from the gastric vagal nerves and the cerebellar interpositus nucleus. Neurosignals2005; 14: 23443.
  • 24
    Zhu JZ, Fei SJ, Zhang JF et al. Lateral hypothalamic area mediated the aggravated effect of microinjection of Baclofen into cerebellar fastigial nucleus on stress gastric mucosal damage in rats. Neurosci Lett2012; 509: 1259.
  • 25
    Gao L, Fei S, Qiao W, Zhang J, Xing H, Du D. Protective effect of chemical stimulation of cerebellar fastigial nucleus on stress gastric mucosal injury in rats. Life Sci2011; 88: 8718.
  • 26
    Paxinos G, Watson C. The Rat Brain in Stereotaxic Coordinates, 6th edn. Sydney: Academic press, 2007.
  • 27
    Busnardo C, Tavares RF, Correa FM. Role of N-methyl-D-aspartate and non-N-methyl -D-aspartate receptors in the cardiovascular effects of L-glutamate microinjection into the hypothalamic paraventricular nucleus of unanesthetized rats. J Neurosci Res2009; 87: 206677.
  • 28
    Jeffery MK, Joseph A, Beatty HR, Little ED, Plowey TG. Chronic exercise alters caudal hypothalamic regulation of the cardiovascular system in hypertensive rats. Am J Physiol Regulatory Integrative Comp Physiol2001; 280: R38997.
  • 29
    Shiramine K, Aou S, Hori T. Lateral hypothalamic injection of GABAA antagonist induces gastric vagus-mediated hypocalcemia in the rat. Am J Physiol1997; 274: R1492500.
  • 30
    Du DS, Ma XB, Zhang JF et al. The protective effect of capsaicin receptor-mediated genistein postconditioning on gastric ischemia- reperfusion injury in rats. Dig Dis Sci2010; 55: 30707.
  • 31
    Lisander B, Martner J. Integrated somatomotor, cardiovascular and gastro intestinal adjustments induced from the cerebellar fastigial nucleus. Acta Physiol Scand1975; 94: 35867.
  • 32
    Manchanda SK, Tandon OP, Aneja IS. Role of the cerebellum in the control of gastrointestinal motility. J Neural Transm1972; 33: 195209.
  • 33
    Li B, Guo CL, Tang J, Zhu JN, Wang JJ. Cerebellar fastigial nuclear inputs and peripheral feeding signals converge on neurons in the dorsomedial hypothalamic nucleus. Neurosignals2009; 17: 13243.
  • 34
    Min B, Oomura Y, Katafuchi T. Responses of rat lateral hypothalamic neuronal activity to fastigial nucleus stimulation. J Neurophysiol1989; 61: 117884.
  • 35
    Maksay G. Dissociation of muscimol, SR95531, and strychnine from GABA and glycine receptors, respectively, suggest similar cooperative interactions. J Neurochemistry1990; 54: 19616.
  • 36
    Todd AJ, Sullivan AC. Light microscope study of the coexistence of GABA- like and glycine-like immunoreactivities in the spinal cord of the rat. J Comparative Neurol1990; 296: 496505.
  • 37
    Ottersen OP, Stom TM, Somogyi P. Colocalization of glycineqike and GABA-like immunoreactivities in Golgi cell terminals in the rat cerebellum: a postembedding light and electron microscopic study. Brain Res1988; 450: 34253.
  • 38
    Haines DE, Dietrichs E, Mihailoff GA, McDonald EF. The cerebellar-hypothalamic axis: basic circuits and clinical observations. Int Rev Neurobiol1997; 41: 83107.
  • 39
    Jansen AS, Hoffman JL, Loewy AD. CNS sites involved in sympathetic and parasympathetic control of the pancreas: a viral tracing study. Brain Res1997; 766: 2938.
  • 40
    Shiramine K, Aou S, Hori T. Lateral hypothalamic injection of GABAA antagonist induces gastric vagus-mediated hypocalcemia in the rat. Am J Physiol1997; 273: R1492500.
  • 41
    Gao J, Zhong MK, Fan ZD et al. SOD1 overexpression in paraventricular nucleus improves post-infarct myocardial remodeling and ventricular function. Pflugers Arch-Eur J Physiol2012; 463: 297307.
  • 42
    Zhou LM, Shi Z, Gao J et al. Angiotensin-(1-7) and angiotension II in the rostral ventrolateral medulla modulate the cardiac sympathetic afferent reflex and sympathetic activity in rats. Pflugers Arch-Eur J Physiol2010; 459: 6818.
  • 43
    DiBona GF. Nervous kidney. Interaction between renal sympathetic nerves and the renin- angiotensin system in the control of renal function. Hypertension2000; 36: 10838.
  • 44
    Nagahama K, Matsunaga Y, Kawachi M et al. Acotiamide, a new orally active acetylcholinesterase inhibitor, stimulates gastrointestinal motor activity in conscious dogs. Neurogastroenterol Motil2012; 24: 56674.
  • 45
    Du DS, Ma XB, Zhang JF, Zhang YM, Zhou XY, Li Y. Cellular and molecular mechanisms of 17β-estradiol postconditioning protection against gastric mucosal injury induced by ischemia/reperfusion in rats. Life Sci2010; 86: 308.
  • 46
    Bao L, Yao XS, Tsi D et al.Protective effects of bilberry (Vaccinium myrtillus L) extract on KbrO3-induced kidney damage in mice. J Agri Food Chemistry2008; 56: 4205.
  • 47
    Zhang JF, Zheng F. The role of paraventricular nucleus of hypothalamus in stress-ulcer formation in rats. Brain Res1997; 761: 2039.