SEARCH

SEARCH BY CITATION

References

  • 1
    Knowles CH, Aziz Q. Visceral hypersensitivity in non-erosive reflux disease. Gut 2008; 57: 67483.
  • 2
    Nagahara A, Miwa H, Minoo T et al. Increased esophageal sensitivity to acid and saline in patients with non erosive gastroesophageal reflux disease. J Clin Gastroenterol 2006; 40: 8915.
  • 3
    Sarkar S, Hobson AR, Hughes A et al. The prostaglandin E2 receptor-1 (EP-1) mediates acid-induced visceral pain hypersensitivity in humans. Gastroenterology 2003; 124: 1825.
  • 4
    Trimble KC, Pryde A, Heading RC. Lowered oesophageal sensory thresholds in patients with symptomatic but not excess gastro-oesophageal reflux: evidence for a spectrum of visceral sensitivity in GORD. Gut 1995; 37: 712.
  • 5
    Emerenziani S, Sifrim D, Habib FI et al. Presence of gas in the refluxate enhances reflux perception in non-erosive patients with physiological acid exposure of the oesophagus. Gut 2008; 57: 4437.
  • 6
    Savarino E, Zentilin P, Tutuian R et al. The role of nonacid reflux in NERD: lessons learned from impedance-pH monitoring in 150 patients off therapy. Am J Gastroenterol 2008; 103: 268593.
    Direct Link:
  • 7
    Ribolsi M, Emerenziani S, Petitti T et al. Increased frequency and enhanced perception of reflux in non-erosive reflux disease patients non-responders to proton pump inhibitors. Dig Liver Dis 2012; 44: 54954.
  • 8
    Hu W, Martin C, Talley J. Intraesophageal acid perfusion sensitizes the esophagus to mechanical distension: a barostat study. Am J Gastroenterol 2000; 95: 218994.
    Direct Link:
  • 9
    Fass R, Naliboff B, Higa L et al. Differential effect of long-term esophageal acid exposure in mechanosensitivity and chemosensitivity in humans. Gastroenterology 1998; 115: 136373.
  • 10
    Mehta AJ, De Caestecker JS, Camm AJ et al. Sensitization to painful distention and abnormal sensory perception in the esophagus. Gastroenterology 1995; 8: 3119.
  • 11
    Peghini PL, Johnston BT, Leite LP et al. Mucosal acid exposure sensitized a subset of normal subjects to intra-esophageal balloon distention. Eur J Gastroenterol Hepatol 1996; 8: 97983.
  • 12
    Matthews PJ, Knowles CH, Chua YC et al. Effects of the concentration and frequency of acid infusion on the development and maintenance of esophageal hyperalgesia in a human volunteer model. Am J Physiol Gastrointest Liver Physiol 2008; 294: G9147.
  • 13
    Zerbib F, Duriez A, Roman S et al. Determinants of gastro-oesophageal reflux perception in patients with persistent symptoms despite proton pump inhibitors. Gut 2008; 57: 15660.
  • 14
    Bredenoord AJ, Weusten BL, Curvers WL et al. Determinants of perception of heartburn and regurgitation. Gut 2006; 55: 31338.
  • 15
    Ferrus JA, Zapardiel J, Sobreviela E. Management of gastroesophageal reflux in primary care setting in Spain: SYMPATHY I study. Eur J Gastroenterol Hepatol 2009; 21: 126978.
  • 16
    Sifrim D, Holloway R, Silny J et al. Acid, nonacid, and gas reflux in patients with gastroesophageal reflux disease during ambulatory 24-hour pH-impedance recordings. Gastroenterology 2001; 120: 158898.
  • 17
    Sifrim D. Acid, weakly acidic and non-acid gastro-oesophageal reflux: differences, prevalence and clinical relevance. Eur J Gastroenterol Hepatol 2004; 16: 82330.
  • 18
    Smout AJ, Breedijk M, van der Zouw C et al. Physiological gastroesophageal reflux and esophageal motor activity studied with a new system for 24-hour recording and automated analysis. Dig Dis Sci 1989; 34: 3728.
  • 19
    Wiener GJ, Richter JE, Copper JB et al. The symptom index: a clinically important parameter of ambulatory 24-hour esophageal pH monitoring. Am J Gastroenterol 1988; 83: 35861.
  • 20
    Weusten BL, Roelofs JM, Akkermans LM et al. The symptom-association probability: an improved method for symptom analysis of 24-hour esophageal pH data. Gastroenterology 1994; 107: 17415.
  • 21
    Caviglia R, Ribolsi M, Maggiano N et al. Dilated intercellular spaces of esophageal epithelium in non erosive reflux disease patients with physiological esophageal acid exposure. Am J Gastroenterol 2005; 100: 5438.
  • 22
    Woodland P, Al-Zinaty M, Yazaki E et al. In vivo evaluation of acid-induced changes in esophageal mucosa integrity and sensitivity in non-erosive reflux disease. Gut 2013; 62: 125661.
  • 23
    Matthews PJ, Aziz Q, Facer P et al. Increased capsaicin receptor TRPV1 nerve fibres in the inflamed human esophagus. Eur J Gastroenterol Hepatol 2004; 16: 897902.