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  • Aker J, Borst JW, Karlova R, de Vries S. 2006. The Arabidopsis thaliana AAA protein CDC48A interacts in vivo with the somatic embryogenesis receptor-like kinase 1 receptor at the plasma membrane. Journal of Structural Biology 156: 6271.
  • Bertea CM, Freije JR, van der Woude H, Verstappen FW, Perk L, Marquez V, De Kraker JW, Posthumus MA, Jansen BJ, de Groot A et al. 2005. Identification of intermediates and enzymes involved in the early steps of artemisinin biosynthesis in Artemisia annua. Planta Medica 71: 4047.
  • Bertea CM, Voster A, Verstappen FW, Maffei M, Beekwilder J, Bouwmeester HJ. 2006. Isoprenoid biosynthesis in Artemisia annua: cloning and heterologous expression of a germacrene A synthase from a glandular trichome cDNA library. Archives of Biochemistry and Biophysics 448: 312.
  • Bouwmeester HJ, Wallaart TE, Janssen MH, van Loo B, Jansen BJ, Posthumus MA, Schmidt CO, De Kraker JW, Konig WA, Franssen MC. 1999. Amorpha-4,11-diene synthase catalyses the first probable step in artemisinin biosynthesis. Phytochemistry 52: 843854.
  • De Vos R, Moco S, Lommen A, Keurentjes J, Bino RJ, Hall RD. 2007. Untargeted large-scale plant metabolomics using liquid chromatography coupled to mass spectrometry. Nature Protocols 2: 778791.
  • Dieckhaus CM, Fernández-Metzler CL, King R, Krolikowski PH, Baillie TA. 2005. Negative ion tandem mass spectrometry for the detection of glutathione conjugates. Chemical Research in Toxicology 18: 630638.
  • van Engelen FA, Molthoff JW, Conner AJ, Nap JP, Pereira A, Stiekema WJ. 1995. pBINPLUS: an improved plant transformation vector based on pBIN19. Transgenic Research 4: 288290.
  • van Herpen TW, Cankar K, Nogueira M, Bosch D, Bouwmeester HJ, Beekwilder J. 2010. Nicotiana benthamiana as a production platform for artemisinin precursors. PLoS ONE 5: e14222.
  • Kim NC, Kim JG, Kim S, Lim H, Hahm T. 1992. Production of secondary metabolites by tissue culture of Artemisia annua L. Journal of the Korean Agricultural Chemical Society 35: 99105.
  • Kohlen W, Charnikhova T, Liu Q, Bours R, Domagalska MA, Beguerie S, Verstappen F, Leyser O, Bouwmeester H, Ruyter-Spira C. 2011. Strigolactones are transported through the xylem and play a key role in shoot architectural response to phosphate deficiency in nonarbuscular mycorrhizal host Arabidopsis. Plant Physiology 155: 974987.
  • Lengler J, Omann M, Duvier D, Holzmuller H, Gregor W, Salmons B, Gunzburg WH, Renner M. 2006. Cytochrome P450 reductase dependent inhibition of cytochrome P450 2B1 activity: implications for gene directed enzyme prodrug therapy. Biochemical Pharmacology 72: 893901.
  • Liu Q, Majdi M, Cankar K, Goedbloed M, Charnikhova T, Verstappen FWA, de Vos RCH, Beekwilder J, van der Krol S, Bouwmeester HJ. 2011. Reconstitution of the costunolide biosynthetic pathway in yeast and Nicotiana benthamiana. PLoS ONE 6: e23255.
  • Maes L, Van Nieuwerburgh F, Zhang Y, Reed D, Pollier J, Vande Casteele S, Inze D, Covello P, Deforce DLDL, Goossens A. 2011. Dissection of the phytohormonal regulation of trichome formation and biosynthesis of the antimalarial compound artemisinin in Artemisia annua plants. New Phytologist 189: 176189.
  • Mercke P, Bengtsson M, Bouwmeester HJ, Posthumus MA, Brodelius PE. 2000. Molecular cloning, expression, and characterization of amorpha-4,11-diene synthase, a key enzyme of artemisinin biosynthesis in Artemisia annua L. Archives of Biochemistry and Biophysics 381: 173180.
  • Nguyen KT, Arsenault PR, Weathers PJ. 2011. Trichomes + roots + ROS = artemisinin: regulating artemisinin biosynthesis in Artemisia annua L. In Vitro Cellular & Developmental Biology Plant 47: 329338.
  • Nguyen DT, Göpfert JC, Ikezawa N, MacNevin G, Kathiresan M, Conrad J, Spring O, Ro DK. 2010. Biochemical conservation and evolution of germacrene A oxidase in Asteraceae. Journal of Biological Chemistry 285: 16 58816 598.
  • Pompon D, Louerat B, Bronine A, Urban P. 1996. Yeast expression of animal and plant P450s in optimized redox environments. Methods in Enzymology 272: 5164.
  • Ro DK, Paradise EM, Ouellet M, Fisher KJ, Newman KL, Ndungu JM, Ho KA, Eachus RA, Ham TS, Kirby J et al. 2006. Production of the antimalarial drug precursor artemisinic acid in engineered yeast. Nature 440: 940943.
  • Rydén AM, Ruyter-Spira C, Quax WJ, Osada H, Muranaka T, Kayser O, Bouwmeester H. 2010. The molecular cloning of dihydroartemisinic aldehyde reductase and its implication in artemisinin biosynthesis in Artemisia annua. Planta Medica 76: 17781783.
  • Sevrioukova IF, Li H, Zhang H, Peterson JA, Poulos TL. 1999. Structure of a cytochrome P450–redox partner electron-transfer complex. Proceedings of the National Academy of Sciences, USA 96: 18631868.
  • Sy L-K, Brown GD. 2002. The mechanism of the spontaneous autoxidation of dihydroartemisinic acid. Tetrahedron 58: 897908.
  • Teoh KH, Polichuk DR, Reed DW, Covello PS. 2009. Molecular cloning of an aldehyde dehydrogenase implicated in artemisinin biosynthesis in Artemisia annua. Botany 87: 635642.
  • Teoh KH, Polichuk DR, Reed DW, Nowak G, Covello PS. 2006. Artemisia annua L. (Asteraceae) trichome-specific cDNAs reveal CYP71AV1, a cytochrome P450 with a key role in the biosynthesis of the antimalarial sesquiterpene lactone artemisinin. FEBS Letters 580: 14111416.
  • Tikunov Y, Lommen A, De Vos C, Verhoeven HA, Bino RJ, Hall RD, Bovy AG. 2005. A novel approach for nontargeted data analysis for metabolomics. Large-scale profiling of tomato fruit volatiles. Plant Physiology 139: 11251137.
  • Wallaart TE, Pras N, Beekman AC, Quax WJ. 2000. Seasonal variation of artemisinin and its biosynthetic precursors in plants of Artemisia annua of different geographical origin: proof for the existence of chemotypes. Planta Medica 66: 5762.
  • Wallaart TE, van Uden W, Lubberink HG, Woerdenbag HJ, Pras N, Quax WJ. 1999. Isolation and identification of dihydroartemisinic acid from Artemisia annua and its possible role in the biosynthesis of artemisinin. Journal of Natural Products 62: 430433.
  • Wang Y, Yang K, Jing F, Li M, Deng T, Huang R, Wang B, Wang G, Sun X, Tang KX. 2011. Cloning and characterization of trichome-specific promoter of cpr71av1 gene involved in artemisinin biosynthesis in Artemisia annua L. Molecular Biology 45: 751758.
  • Yoo SD, Cho YH, Sheen J. 2007. Arabidopsis mesophyll protoplasts: a versatile cell system for transient gene expression analysis. Nature Protocols 2: 15651572.
  • Zhang Y, Nowak G, Reed DW, Covello PS. 2011. The production of artemisinin precursors in tobacco. Plant Biotechnology Journal 9: 445454.
  • Zhang Y, Teoh KH, Reed DW, Maes L, Goossens A, Olson DJ, Ross AR, Covello PS. 2008. The molecular cloning of artemisinic aldehyde Δ11(13) reductase and its role in glandular trichome-dependent biosynthesis of artemisinin in Artemisia annua. Journal of Biological Chemistry 283: 21 50121 508.