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nph12776-sup-0001-FiguresS1-S5.docWord document24012K

Fig. S1 Southern blot hybridization analyses of ΔFgFKBP12, ΔFgSIT4, ΔFgPPG1 and ΔFgTIP41, ΔFgAREA and their complemented strains of Fusarium graminearum.

Fig. S2 The colony morphology of the mutants ΔFgFKBP12, ΔFgFKBP20 and ΔFgFKBP54 of Fusarium graminearum on potato dextrose agar (PDA) plates and their sensitivity to rapamycin.

Fig. S3 The FgFKBP12 deletion mutant (ΔFgFKBP12) of Fusarium graminearum showed resistance to rapamycin and FK506.

Fig. S4 A rapamycin-resistant (RR) mutant generated by UV irradiation harbors a point mutant at the codon 1866 in the Fkbp12-rapamycin binding (FRB) domain of FgTor kinase of Fusarium graminearum.

Fig. S5 Nitrogen (N) utilization, virulence and deoxynivalenol (DON) production of ΔFgAREA of Fusarium graminearum.

nph12776-sup-0002-TablesS1-S3.docWord document243K

Table S1 Summary of the components of the target of rapamycin (TOR) pathway in Fusarium graminearum and their orthologs in Saccharomyces cerevisiae

Table S2 A total of 138 oligonucleotide primers were used in this study

Table S3 Genes encoding catalytic subunits of type 2A phosphatase and type 2A-like phosphatase in Fusarium graminearum