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Does vitamin D affect timing of menarche?

Authors

  • Anna Chew,

    Corresponding author
    • Bone Metabolism Laboratory, Jean Mayer United States Department of Agriculture Human Nutrition Research Center on Aging, Boston, Massachusetts, USA
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  • Susan S Harris

    1. Bone Metabolism Laboratory, Jean Mayer United States Department of Agriculture Human Nutrition Research Center on Aging, Boston, Massachusetts, USA
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Correspondence: A Chew, Bone Metabolism Laboratory, Jean Mayer United States Department of Agriculture Human Nutrition Research Center on Aging, 711 Washington Street, Boston, Massachusetts 02111, USA. E-mail: Anna.Chew@tufts.edu. Phone: +1-617-556-3000. Fax: +1-617-556-3344.

Abstract

In a recently published prospective study, Villamor et al. found increased risk of early menarche in vitamin D-deficient girls compared to vitamin D-sufficient girls in Bogota, Columbia. The association was not fully explained by differences in body mass index-for-age z-scores. The mechanism for the association, if real, has not been elucidated, but could potentially involve vitamin D receptor polymorphisms. Early menarche and vitamin D deficiency are both associated with poor health outcomes, and further exploration of their association is important for women's health.

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