Annals of the New York Academy of Sciences

Cover image for Annals of the New York Academy of Sciences

December 1954

Volume 60 6-Mercaptopurine

Pages 185–507

    1. THE BIOSYNTHESIS OF NUCLEIC ACIDS AS A BASIS FOR AN APPROACH TO CHEMOTHERAPY (pages 185–194)

      George Bosworth Brown

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1954.tb40007.x

    2. THE CHEMISTRY AND BIOCHEMISTRY OF PURINE ANALOGS (pages 195–199)

      George H. Hitchings and Gertrude B. Elion

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1954.tb40008.x

    3. MICROBIOLOGICAL EFFECTS OF 6-MERCAPTOPURINE (pages 200–206)

      Gertrude B. Elion, Samuel Singer and George H. Hitchings

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1954.tb40009.x

    4. ACTIVITIES OF 6-MERCAPTOPURINE AND RELATED COMPOUNDS ON EMBRYONIC AND REGENERATING TISSUES OF RANA PIPIENS (pages 207–211)

      Samuel Bieber, Rosalyn Bieber and George H. Hitchings

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1954.tb40010.x

    5. BIOLOGICAL ACTIVITIES OF 6-MERCAPTOPURINE: EFFECTS ON STREPTOCOCCUS FAECALIS (pages 212–219)

      Dorris J. Hutchison

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1954.tb40011.x

    6. THE EFFECT OF 6-MERCAPTOPURINE ON THE RAT FETUS AND ON REPRODUCTION OF THE RAT (pages 220–227)

      John B. Thiersch

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1954.tb40012.x

    7. EFFECTS OF 6-MERCAPTOPURINE ON EXPERIMENTAL TUMORS IN TISSUE CULTURE (pages 228–234)

      John J. Biesele

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1954.tb40013.x

    8. EFFECTS OF 6-MERCAPTOPURINE AND ANALOGS ON EXPERIMENTAL TUMORS (pages 235–243)

      Donald A. Clarke, Frederick S. Philips, Stephen S. Sternberg and C. Chester Stock

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1954.tb40014.x

    9. RESPONSE OF ACUTE LYMPHOCYTIC LEUKEMIAS TO THE PURINE ANTAGONIST 6-MERCAPTOPURINE (pages 244–250)

      L. W. Law, V. Taormina and P. J. Boyle

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1954.tb40015.x

    10. STUDIES ON THE TOXICITY AND ANTILEUKEMIC ACTION OF 6-MERCAPTOPURINE IN MICE (pages 251–266)

      Abraham Goldin, John M. Venditti, Stewart R. Humphreys, Don Dennis, Nathan Mantel and Samuel W. Greenhouse

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1954.tb40016.x

    11. EFFECTS OF 6-MERCAPTOPURINE ON EXPERIMENTAL TUMORS (pages 267–272)

      Howard E. Skipper

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1954.tb40017.x

    12. THE EFFECTS OF 6-MERCAPTOPURINE, 8-AZAGUANINE, AND 1,4-DIMETHANESULFONYLOXYBUTANE ON AN EXPERIMENTAL BRAIN TUMOR: PRELIMINARY OBSERVATIONS (pages 273–282)

      Alfred Gellhorn, Edith R. Peterson, Alice Kells, Erich Hirschberg and Margaret R. Murray

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1954.tb40018.x

    13. THE TOXIC EFFECTS OF 6-MERCAPTOPURINE AND RELATED COMPOUNDS (pages 283–296)

      Frederick S. Philips, Stephen S. Sternberg, Leonard Hamilton and Donald A. Clarke

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1954.tb40019.x

    14. THE FATE OF 6-MERCAPTOPURINE IN MICE (pages 297–303)

      Gertrude B. Elion, Samuel Bieber and George H. Hitchings

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1954.tb40020.x

    15. THE FATE OF 6-MERCAPTOPURINE IN MAN (pages 304–314)

      Leonard Hamilton and Gertrude B. Elion

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1954.tb40021.x

    16. ON THE MECHANISM OF ACTION OF 6-MERCAPTOPURINE (pages 315–321)

      Howard E. Skipper

      Article first published online: 28 JUN 2008 | DOI: 10.1111/j.1749-6632.1954.tb40022.x

    17. THE NATURAL HISTORY OF UNTREATED ACUTE LEUKEMIA (pages 322–358)

      Harold Tivey

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1954.tb40023.x

    18. CLINICAL STUDIES ON 6-MERCAPTOPURINE (pages 359–368)

      Joseph H. Burchenal, R. R. Ellison, M. L. Murphy, D. A. Karnofsky, M. P. Sykes, T. C. Tan, A. C. Mermann, M. Yuceoglu, W. P. L. Myers, I. Krakoff and N. Alberstadt

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1954.tb40024.x

    19. STATISTICAL ANALYSIS OF CLINICAL RESULTS FROM 6-MERCAPTOPURINE (pages 369–373)

      Irwin D. J. Bross

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1954.tb40025.x

    20. CLINICAL EXPERIENCE WITH 6-MERCAPTOPURINE IN HUMAN NEOPLASIA (pages 374–384)

      B. E. Hall, M. D. Richards, F. M. Willett and T. V. Feichtmeir

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1954.tb40026.x

    21. A STUDY OF 61 LEUKEMIAS TREATED WITH 6-MERCAPTOPURINE (pages 385–401)

      Jean Bernard and M. Seligmann

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1954.tb40027.x

    22. THE TREATMENT OF BLASTIC LEUKEMIAS WITH 6-MERCAPTOPURINE (pages 402–410)

      Felipe Jiménez De Asúa

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1954.tb40028.x

    23. ONE-YEAR EVALUATION OF 6-MERCAPTOPURINE IN THE TREATMENT OF LEUKEMIA (page 411)

      Charles A. Doan, K. Wiseman and Bertha Bouroncle

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1954.tb40029.x

    24. SUMMARY OF EXPERIENCE WITH 6-MERCAPTOPURINE (pages 412–414)

      Sidney Farber

      Article first published online: 28 JUN 2008 | DOI: 10.1111/j.1749-6632.1954.tb40030.x

    25. LEUKEMIA IN CHILDREN: TREATMENT OF 22 CASES WITH 6-MERCAPTOPURINE (pages 415–424)

      Mila Pierce

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1954.tb40031.x

    26. 6-MERCAPTOPURINE THERAPY IN NEOPLASTIC DISEASE (pages 425–429)

      R. Wayne Rundles and John A. Crago

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1954.tb40032.x

    27. THE THERAPEUTIC EFFECT OF MERCAPTOPURINE IN A VARIETY OF HUMAN NEOPLASTIC DISEASES (pages 430–435)

      George A. Hyman, Alfred Gellhorn and James A. Wolff

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1954.tb40033.x

    28. TREATMENT OF LEUKEMIA AND RELATED DISORDERS WITH 6-MERCAPTOPURINE (pages 436–438)

      F. H. Bethell and D. S. Thompson

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1954.tb40034.x

    29. THE USE OF 6-MERCAPTOPURINE IN ACUTE LEUKEMIA (page 447)

      William Dameshek

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1954.tb40036.x

    30. ROLE OF MERCAPTOPURINE IN THE TREATMENT OF LEUKEMIA AND RELATED DISEASES (pages 448–453)

      Nathan Rosenthal, Robert L. Rosenthal and Stanley L. Lee

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1954.tb40037.x

    31. REPORT ON 6-MERCAPTOPURINE (pages 454–457)

      V. P. Sydenstricker

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1954.tb40038.x

    32. RESULTS OBTAINED IN THE TREATMENT OF ACUTE LEUKEMIA AND LYMPHOSARCOMA WITH 6-MERCAPTOPURINE (pages 458–460)

      E. Clarence Rice

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1954.tb40039.x

    33. 6-MERCAPTOPURINE THERAPY IN LEUKEMIA (pages 461–465)

      Joseph M. Hill and Jorge Lajous

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1954.tb40040.x

    34. 6-MERCAPTOPURINE IN ACUTE LEUKEMIA (pages 466–467)

      Eugene L. Lozner

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1954.tb40041.x

    35. CLINICAL EXPERIENCE USING 6-MERCAPTOPURINE IN CHILDHOOD LEUKEMIA (pages 468–471)

      W. A. Newton Jr.

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1954.tb40042.x

    36. CLINICAL EVALUATION OF 6-MERCAPTOPURINE (pages 472–477)

      Arthur Sawitsky and Charles R. Ream

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1954.tb40043.x

    37. A CLINICAL STUDY OF 6-MERCAPTOPURINE (pages 478–482)

      Paul C. Gaffney and William M. Cooper

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1954.tb40044.x

    38. THE TREATMENT OF LEUKEMIA WITH 6-MERCAPTOPURINE (pages 483–491)

      Quin B. DeMarsh

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1954.tb40045.x

    39. THE EFFECT OF 6-MERCAPTOPURINE IN ACUTE LEUKEMIA OF CHILDREN AND ADULTS: A PRELIMINARY REPORT (pages 492–498)

      N. L. Petrakis, D. A. Wood, S. R. Mettier, W. C. Deamer, S. A. Gellert, J. G. Li and M. E. Leonard

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1954.tb40046.x

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