Annals of the New York Academy of Sciences

Cover image for Annals of the New York Academy of Sciences

September 1959

Volume 82 Current Trends in Research and Clinical Management of Diabetes

Pages 195–643

    1. INTRODUCTION (pages 195–196)

      Peter H. Forsham

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1959.tb44899.x

  1. Part I. Diabetes Mellitus: Certain Fundamental Clinical and Socioeconomic Considerations

    1. Top of page
    2. Part I. Diabetes Mellitus: Certain Fundamental Clinical and Socioeconomic Considerations
    3. Part II. Recent Advances In Studies of Insulin Secretion and Certain Metabolic Effects
    4. Part III. Biochemistry and Physiology of Insulin and the Sulfonylurea Compounds
    5. Part IV. The Status of Oral Agents in the Therapy of Diabetes
    1. THE GENETICS OF DIABETES: A REVIEW (pages 197–207)

      Arthur G. Steinberg

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1959.tb44900.x

    2. THE EARLY RECOGNITION OF DIABETES MELLITUS (pages 208–218)

      Stefan S. Fajans and Jerome W. Conn

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1959.tb44901.x

    3. PREGNANCY AND THE PREDIABETIC STATE (pages 219–228)

      Hugh L. C. Wilkerson

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1959.tb44902.x

    4. A CURRENT ESTIMATE OF THE PREVALENCE OF DIABETES MELLITUS IN THE UNITED STATES (pages 229–235)

      Quentin R. Remein

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1959.tb44903.x

    5. DIABETES MELLITUS AND THE LIVING MICROVASCULAR SYSTEM (pages 236–244)

      Edward H. Bloch

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1959.tb44904.x

    6. DIABETIC NEUROPATHY: EVALUATION OF FACTORS IN ONSET (pages 245–250)

      Max Ellenberg

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1959.tb44905.x

    7. ACCEPTABILITY OF DIABETICS FOR LIFE INSURANCE (pages 251–257)

      Paul S. Entmacher

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1959.tb44906.x

    8. EMPLOYABILITY OF THE DIABETIC (pages 258–265)

      Harold Brandaleone

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1959.tb44907.x

  2. Part II. Recent Advances In Studies of Insulin Secretion and Certain Metabolic Effects

    1. Top of page
    2. Part I. Diabetes Mellitus: Certain Fundamental Clinical and Socioeconomic Considerations
    3. Part II. Recent Advances In Studies of Insulin Secretion and Certain Metabolic Effects
    4. Part III. Biochemistry and Physiology of Insulin and the Sulfonylurea Compounds
    5. Part IV. The Status of Oral Agents in the Therapy of Diabetes
    1. ISLET CELL FUNCTION (pages 266–286)

      R. E. Haist

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1959.tb44908.x

    2. ELECTRON MICROSCOPY OF THE ISLETS OF LANGERHANS (pages 287–300)

      Paul E. Lacy and W. Stanley Hartroft

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1959.tb44909.x

    3. Lacy & Hartroft: Microscopy of Islets of Langerhans : Discussion of the Paper (page 301)

      G. A. WRENSHALL

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1959.tb44910.x

    4. MORPHOLOGIC REFLECTION OF INCREASING INSULINOGENESIS DURING CHRONIC HYPERGLYCEMIA IN THE RABBIT (pages 319–328)

      Bruno W. Volk and Sydney S. Lazarus

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1959.tb44912.x

    5. STUDIES ON THE MECHANISM OF CAPTURE AND DEGRADATION OF INSULIN-I131 BY THE CYCLICALLY PERFUSED RAT LIVER (pages 329–337)

      Glenn E. Mortimore and Frank Tietze

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1959.tb44913.x

    6. RECENT STUDIES ON INSULIN-BINDING ANTIBODIES (pages 338–344)

      Solomon A. Berson and Rosalyn S. Yalow

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1959.tb44914.x

    7. INSULIN-STIMULATED GLYCOGEN FORMATION IN RAT DIAPHRAGM (pages 345–353)

      Joseph Larner, Carlos Villar Palasi and David J. Richman

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1959.tb44915.x

  3. Part III. Biochemistry and Physiology of Insulin and the Sulfonylurea Compounds

    1. Top of page
    2. Part I. Diabetes Mellitus: Certain Fundamental Clinical and Socioeconomic Considerations
    3. Part II. Recent Advances In Studies of Insulin Secretion and Certain Metabolic Effects
    4. Part III. Biochemistry and Physiology of Insulin and the Sulfonylurea Compounds
    5. Part IV. The Status of Oral Agents in the Therapy of Diabetes
    1. EFFECT OF 6-DEOXY-6-FLUOROGLUCOSE ON GLUCOSE PERMEATION OF THE CELL (pages 374–377)

      Arne N. Wick and George S. Serif

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1959.tb44918.x

    2. GLUCOSE TRANSPORT THEORY OF INSULIN ACTION (pages 378–386)

      M. S. Goldstein

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1959.tb44919.x

    3. REGULATION OF GLUCOSE UPTAKE IN HEART MUSCLE FROM NORMAL AND ALLOXAN-DIABETIC RATS: THE EFFECTS OF INSULIN, GROWTH HORMONE, CORTISONE, AND ANOXIA (pages 387–402)

      H. E. Morgan, M. J. Henderson, D. M. Regen and C. R. Park

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1959.tb44920.x

    4. EFFECTS OF INSULIN ON ADIPOSE TISSUE (pages 403–411)

      George F. Cahill Jr., Bernard Jeanrenaud, Bernard Leboeuf and Albert E. Renold

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1959.tb44921.x

    5. EFFECTS OF INSULIN AND TOLBUTAMIDE ON BLOOD GLUCOSE ENTRY AND REMOVAL RATES (pages 412–419)

      George A. Reichard, A. Gerson Jacobs, Bernice Friedmann, Philip Kimbel, Norman J. Hochella and Sidney Weinhouse

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1959.tb44922.x

    6. INFLUENCES OF GLUCOSE LOADING AND OF INJECTED INSULIN ON HEPATIC GLUCOSE OUTPUT (pages 420–430)

      Robert Steele

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1959.tb44923.x

    7. EFFECTS OF EXOGENOUS AND ENDOGENOUS INSULIN ON GLUCOSE UTILIZATION AND PRODUCTION (pages 431–451)

      R. C. de Bodo, N. Altszuler, A. Dunn, R. Steele, D. T. Armstrong and J. S. Bishop

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1959.tb44924.x

    8. HEPATIC ACTION OF INSULIN (pages 452–459)

      Robert Mahler, W. C. Shoemaker and James Ashmore

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1959.tb44925.x

    9. FURTHER STUDIES ON THE SIGNIFICANT ROLE OF THE LIVER IN SULFONYLUREA HYPOGLYCEMIA (pages 460–478)

      Thomas F. Frawley, Thomas F. Shelley, John W. Runyan Jr., Edward J. Margulies and John J. Cincotti

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1959.tb44926.x

    10. CLINICAL AND EXPERIMENTAL STUDIES OF INSULIN SECRETION FOLLOWING TOLBUTAMIDE AND METAHEXAMIDE ADMINISTRATION (pages 479–495)

      Ernst F. Pfeiffer, Margret Pfeiffer, Hans Ditschuneit and Chang-Su Ahn

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1959.tb44927.x

    11. DETERMINATION OF METAHEXAMIDE IN HUMAN PLASMA (pages 496–501)

      Arlington A. Forist

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1959.tb44928.x

    12. DETERMINATION OF THE HALF LIFE OF METAHEXAMIDE IN NORMAL HUMANS (pages 502–507)

      Leo L. Morgenstern and Edward R. Garrett

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1959.tb44929.x

  4. Part IV. The Status of Oral Agents in the Therapy of Diabetes

    1. Top of page
    2. Part I. Diabetes Mellitus: Certain Fundamental Clinical and Socioeconomic Considerations
    3. Part II. Recent Advances In Studies of Insulin Secretion and Certain Metabolic Effects
    4. Part III. Biochemistry and Physiology of Insulin and the Sulfonylurea Compounds
    5. Part IV. The Status of Oral Agents in the Therapy of Diabetes
    1. PHARMACOLOGICAL STUDIES OF THE SULFONYLUREAS (pages 508–512)

      Alfred Bänder

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1959.tb44930.x

    2. ROLE OF ORAL BLOOD SUGAR-LOWERING AGENTS IN THE MANAGEMENT OF DIABETES (pages 513–530)

      Robert F. Bradley

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1959.tb44931.x

    3. AN ASSESSMENT OF ORAL ANTIDIABETIC THERAPY (pages 531–536)

      Henry Dolger

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1959.tb44932.x

    4. CORRELATION OF PLASMA LEVELS OF ORAL ANTIDIABETIC AGENTS WITH BLOOD SUGAR RESPONSES (pages 537–546)

      W. Creutzfeldt, F. Andreu-Kern and R. Discher

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1959.tb44933.x

    5. COMPARATIVE PHARMACOLOGY AND CLINICAL RESPONSES TO METAHEXAMIDE (pages 547–559)

      George J. Hamwi, Thomas G. Skillman, Fred A. Kruger, William H. Roush and Lucy R. Freedy

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1959.tb44934.x

    6. TOLBUTAMIDE STUDIES IN PREDIABETES (pages 560–569)

      Henrique Paulo Barros Barreto and Lillian Recant

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1959.tb44935.x

    7. COMBINED INSULIN-TOLBUTAMIDE THERAPY IN THE MANAGEMENT OF INSULIN-DEPENDENT DIABETES (pages 585–589)

      Maximilian Fabrykant and Benjamin I. Ashe

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1959.tb44937.x

    8. PHYSIOLOGICAL BASIS OF THE EFFECTIVENESS OF COMBINED INSULIN-TOLBUTAMIDE THERAPY IN STABLE DIABETES (pages 590–602)

      Sydney S. Lazarus and Bruno W. Volk

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1959.tb44938.x

    9. THE BIGUANIDES: THEIR ROLE IN THIS ERA OF THE PRECISE TOOL (pages 603–613)

      Leo P. Krall

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1959.tb44939.x

    10. METAHEXAMIDE IN DIABETES THERAPY (pages 614–617)

      James M. Moss and DeWitt DeLawter

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1959.tb44940.x

    11. CLINICAL STUDIES WITH METAHEXAMIDE (pages 618–623)

      Samuel J. N. Sugar and Lawrence J. Thomas

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1959.tb44941.x

    12. LABORATORY AND CLINICAL OBSERVATIONS WITH A NEW SULFONYLUREA (pages 624–631)

      A. A. Silver, H. Wishinsky, R. F. Caplan and C. Monk

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1959.tb44942.x

    13. BLOOD LEVELS FOR METAHEXAMIDE AND CAPILLARY VENOUS DIFFERENCES FOR GLUCOSE IN ELDERLY DIABETIC MEN USING INSULIN OR METAHEXAMIDE (pages 632–639)

      T. H. McGavack, H. G. Bauer, K. Y. T. Kao and E. Sisler

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1959.tb44943.x

    14. SUMMARY OF THE MONOGRAPH (pages 640–643)

      Peter H. Forsham

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1959.tb44944.x

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