Annals of the New York Academy of Sciences

Cover image for Annals of the New York Academy of Sciences

May 1963

Volume 103 Antibody to Enzymes- A Three-Compnent System

Pages 495–1154

    1. INTRODUCTION: IMMUNOCHEMISTRY OF ENZYMES (pages 495–548)

      B. Cinader

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1963.tb53717.x

  1. Part I: Aspects of Two-Component Immunology

    1. Top of page
    2. Part I: Aspects of Two-Component Immunology
    3. Part II. Reaction Mechanisms of the Interaction of Enzymes, Antibody, and Substrate
    4. Part III. The Effect of Antibodies on Various Enzymes
    5. Part III. The Effect of Antibodyies on Various Enzymes
    6. Part III. The Effect of Antibodies on Various Enzymes
    7. DISCUSSION
    8. Part IV. Interaction of Enzyme, Coenzyme, and Substrate with Antibody A. Reaction Mechanism
    9. B. Multiple Forms of Enzymes
    10. Part V. Use of Antibodies in the Discrimination of Multiple Molecular Forms of Enzymes
    11. DISCUSSION
    12. Part VI. Antibodies as Tools in Studies of Biosynthesis of Enzymes
    13. DISCUSSION
    1. NATURE OF ANTIGENIC DETERMINANTS IN PROTEINS AND SYNTHETIC POLYPEPTIDES (pages 549–581)

      Paul H. Maurer

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1963.tb53718.x

    2. THE CHEMICAL NATURE OF ANTIBODY MOLECULES AND THEIR COMBINING SITES (pages 582–594)

      David Pressman, Allan L. Grossberg, Oliver Roholt, Peter Stelos and Yasuo Yagi

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1963.tb53719.x

    3. BINDING SITE TOPOLOGY OF ENZYMES AND ANTIBODIES INDUCED BY THE SAME DETERMINANTS (pages 595–610)

      Sam M. Beiser and Stuart W. Tanenbaum

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1963.tb53720.x

    4. THE KINETICS OF THE REACTIONS BETWEEN ANTIBODIES TO THE 2, 4 DINITROPHENYL GROUP AND SPECIFIC HAPTENS. (pages 611–625)

      Loren A. Day, Julian M. Sturtevant and S. J. Singer

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1963.tb53721.x

    5. KINETICS OF ANTIBODY-HAPTEN INTERACTIONS, (pages 626–629)

      A. H. Sehon

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1963.tb53722.x

    6. PROPERTIES OF THE ACTIVE SITE OF ENZYMES (pages 630–642)

      Daniel E. Koshland Jr.

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1963.tb53723.x

    7. THE USE OF STATISTICAL THEORY IN THE STUDY OF THE PRECIPITIN REACTION (pages 643–652)

      R. V. Webber and J. W. Williams

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1963.tb53724.x

  2. Part II. Reaction Mechanisms of the Interaction of Enzymes, Antibody, and Substrate

    1. Top of page
    2. Part I: Aspects of Two-Component Immunology
    3. Part II. Reaction Mechanisms of the Interaction of Enzymes, Antibody, and Substrate
    4. Part III. The Effect of Antibodies on Various Enzymes
    5. Part III. The Effect of Antibodyies on Various Enzymes
    6. Part III. The Effect of Antibodies on Various Enzymes
    7. DISCUSSION
    8. Part IV. Interaction of Enzyme, Coenzyme, and Substrate with Antibody A. Reaction Mechanism
    9. B. Multiple Forms of Enzymes
    10. Part V. Use of Antibodies in the Discrimination of Multiple Molecular Forms of Enzymes
    11. DISCUSSION
    12. Part VI. Antibodies as Tools in Studies of Biosynthesis of Enzymes
    13. DISCUSSION
    1. STERIC INHIBITION: NEUTRALIZATION OF A VIRUS-BORNE ENZYME (pages 674–687)

      S. Fazekas de St.Groth

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1963.tb53726.x

    2. LUCIFERASE-ANTILUCIFEFUSE, (pages 715–723)

      Frederick I. Tsuji, E. Melvin Gindler and David L. Davis

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1963.tb53728.x

    3. THE INTERACTION BETWEEN XANTHINE OXIDASE AND ITS ANTIBODY (pages 724–734)

      John E. Ultmann and Philip Feigelson

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1963.tb53729.x

  3. Part III. The Effect of Antibodies on Various Enzymes

    1. Top of page
    2. Part I: Aspects of Two-Component Immunology
    3. Part II. Reaction Mechanisms of the Interaction of Enzymes, Antibody, and Substrate
    4. Part III. The Effect of Antibodies on Various Enzymes
    5. Part III. The Effect of Antibodyies on Various Enzymes
    6. Part III. The Effect of Antibodies on Various Enzymes
    7. DISCUSSION
    8. Part IV. Interaction of Enzyme, Coenzyme, and Substrate with Antibody A. Reaction Mechanism
    9. B. Multiple Forms of Enzymes
    10. Part V. Use of Antibodies in the Discrimination of Multiple Molecular Forms of Enzymes
    11. DISCUSSION
    12. Part VI. Antibodies as Tools in Studies of Biosynthesis of Enzymes
    13. DISCUSSION
    1. STRUCTURAL STUDIES ON PEPSINOGEN AND PEPSIN: AN IMMUNOLOGICAL APPROACH, (pages 735–743)

      Helen Van Vunakis and Lawrence Levine

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1963.tb53730.x

    2. ANTIBODIES TO PEPSINOGEN AND PEPSINOGEN MODIFICATIONS (pages 744–753)

      Ruth Arnon and Gertrude E. Perlmann

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1963.tb53731.x

    3. IMMUNOLOGIC STUDIES OF BOVINE RIBONUCLEASE DERIVATIVES (pages 754–764)

      Ray K. Brown

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1963.tb53732.x

  4. Part III. The Effect of Antibodyies on Various Enzymes

    1. Top of page
    2. Part I: Aspects of Two-Component Immunology
    3. Part II. Reaction Mechanisms of the Interaction of Enzymes, Antibody, and Substrate
    4. Part III. The Effect of Antibodies on Various Enzymes
    5. Part III. The Effect of Antibodyies on Various Enzymes
    6. Part III. The Effect of Antibodies on Various Enzymes
    7. DISCUSSION
    8. Part IV. Interaction of Enzyme, Coenzyme, and Substrate with Antibody A. Reaction Mechanism
    9. B. Multiple Forms of Enzymes
    10. Part V. Use of Antibodies in the Discrimination of Multiple Molecular Forms of Enzymes
    11. DISCUSSION
    12. Part VI. Antibodies as Tools in Studies of Biosynthesis of Enzymes
    13. DISCUSSION
    1. STUDIES ON THE ANTIGENIC COMBINING SITES IN BACTERIOPHAGE LYSOZYME (pages 765–772)

      Thomas C. Merigan and William J. Dreyer

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1963.tb53733.x

  5. Part III. The Effect of Antibodies on Various Enzymes

    1. Top of page
    2. Part I: Aspects of Two-Component Immunology
    3. Part II. Reaction Mechanisms of the Interaction of Enzymes, Antibody, and Substrate
    4. Part III. The Effect of Antibodies on Various Enzymes
    5. Part III. The Effect of Antibodyies on Various Enzymes
    6. Part III. The Effect of Antibodies on Various Enzymes
    7. DISCUSSION
    8. Part IV. Interaction of Enzyme, Coenzyme, and Substrate with Antibody A. Reaction Mechanism
    9. B. Multiple Forms of Enzymes
    10. Part V. Use of Antibodies in the Discrimination of Multiple Molecular Forms of Enzymes
    11. DISCUSSION
    12. Part VI. Antibodies as Tools in Studies of Biosynthesis of Enzymes
    13. DISCUSSION
    1. REACTIONS OF RIBOSOMAL-BOUND ENZYME WITH ITS ANTIBODY: AN EXERCISE, (pages 773–792)

      Philip Siekevitz

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1963.tb53734.x

    2. ANTIGENICALLY ACTIVE FRAGMENTS OF TRYPTOPHAN SYNTHETASE, (pages 793–802)

      M. D. Garrick and S. R. Suskind

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1963.tb53735.x

    3. NATURAL INHIBITORS OF FUNGAL PROTEASE (ASPERGILLIN O), (pages 803–815)

      Mario Stefanini and Mustafa Karaca

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1963.tb53736.x

    4. STUDIES ON ANTIBODIES TO COMPONENTS OF COMPLEMENT (pages 816–828)

      O. J. Plescia, T. S. Mao and J. M. Segovia

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1963.tb53737.x

  6. DISCUSSION

    1. Top of page
    2. Part I: Aspects of Two-Component Immunology
    3. Part II. Reaction Mechanisms of the Interaction of Enzymes, Antibody, and Substrate
    4. Part III. The Effect of Antibodies on Various Enzymes
    5. Part III. The Effect of Antibodyies on Various Enzymes
    6. Part III. The Effect of Antibodies on Various Enzymes
    7. DISCUSSION
    8. Part IV. Interaction of Enzyme, Coenzyme, and Substrate with Antibody A. Reaction Mechanism
    9. B. Multiple Forms of Enzymes
    10. Part V. Use of Antibodies in the Discrimination of Multiple Molecular Forms of Enzymes
    11. DISCUSSION
    12. Part VI. Antibodies as Tools in Studies of Biosynthesis of Enzymes
    13. DISCUSSION
    1. Studies on Antibodies to Human C′1-Esterase (pages 829–834)

      I. H. Lepow

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1963.tb53738.x

  7. Part IV. Interaction of Enzyme, Coenzyme, and Substrate with Antibody A. Reaction Mechanism

    1. Top of page
    2. Part I: Aspects of Two-Component Immunology
    3. Part II. Reaction Mechanisms of the Interaction of Enzymes, Antibody, and Substrate
    4. Part III. The Effect of Antibodies on Various Enzymes
    5. Part III. The Effect of Antibodyies on Various Enzymes
    6. Part III. The Effect of Antibodies on Various Enzymes
    7. DISCUSSION
    8. Part IV. Interaction of Enzyme, Coenzyme, and Substrate with Antibody A. Reaction Mechanism
    9. B. Multiple Forms of Enzymes
    10. Part V. Use of Antibodies in the Discrimination of Multiple Molecular Forms of Enzymes
    11. DISCUSSION
    12. Part VI. Antibodies as Tools in Studies of Biosynthesis of Enzymes
    13. DISCUSSION
    1. IMMUNOLOGICAL CHARACTERISTICS OF DEHYDROGENASES (pages 835–848)

      Nathan O. Kaplan and Shirley White

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1963.tb53739.x

  8. B. Multiple Forms of Enzymes

    1. Top of page
    2. Part I: Aspects of Two-Component Immunology
    3. Part II. Reaction Mechanisms of the Interaction of Enzymes, Antibody, and Substrate
    4. Part III. The Effect of Antibodies on Various Enzymes
    5. Part III. The Effect of Antibodyies on Various Enzymes
    6. Part III. The Effect of Antibodies on Various Enzymes
    7. DISCUSSION
    8. Part IV. Interaction of Enzyme, Coenzyme, and Substrate with Antibody A. Reaction Mechanism
    9. B. Multiple Forms of Enzymes
    10. Part V. Use of Antibodies in the Discrimination of Multiple Molecular Forms of Enzymes
    11. DISCUSSION
    12. Part VI. Antibodies as Tools in Studies of Biosynthesis of Enzymes
    13. DISCUSSION
    1. IMMUNOCHEMICAL PROPERTIES OF LACTATE DEHYDROGENASE ISOZYMES (pages 915–929)

      Clement L. Markert and Ettore Appella

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1963.tb53744.x

    2. IMMUNOCHEMICAL STUDIES OF HUMAN LACTIC DEHYDROGENASES (pages 930–937)

      J. S. Nisselbaum and Oscar Rodansky

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1963.tb53745.x

  9. Part V. Use of Antibodies in the Discrimination of Multiple Molecular Forms of Enzymes

    1. Top of page
    2. Part I: Aspects of Two-Component Immunology
    3. Part II. Reaction Mechanisms of the Interaction of Enzymes, Antibody, and Substrate
    4. Part III. The Effect of Antibodies on Various Enzymes
    5. Part III. The Effect of Antibodyies on Various Enzymes
    6. Part III. The Effect of Antibodies on Various Enzymes
    7. DISCUSSION
    8. Part IV. Interaction of Enzyme, Coenzyme, and Substrate with Antibody A. Reaction Mechanism
    9. B. Multiple Forms of Enzymes
    10. Part V. Use of Antibodies in the Discrimination of Multiple Molecular Forms of Enzymes
    11. DISCUSSION
    12. Part VI. Antibodies as Tools in Studies of Biosynthesis of Enzymes
    13. DISCUSSION
  10. DISCUSSION

    1. Top of page
    2. Part I: Aspects of Two-Component Immunology
    3. Part II. Reaction Mechanisms of the Interaction of Enzymes, Antibody, and Substrate
    4. Part III. The Effect of Antibodies on Various Enzymes
    5. Part III. The Effect of Antibodyies on Various Enzymes
    6. Part III. The Effect of Antibodies on Various Enzymes
    7. DISCUSSION
    8. Part IV. Interaction of Enzyme, Coenzyme, and Substrate with Antibody A. Reaction Mechanism
    9. B. Multiple Forms of Enzymes
    10. Part V. Use of Antibodies in the Discrimination of Multiple Molecular Forms of Enzymes
    11. DISCUSSION
    12. Part VI. Antibodies as Tools in Studies of Biosynthesis of Enzymes
    13. DISCUSSION
    1. Stereospecific, Organ-Specific Inhibition of Intestinal Alkaline Phosphatase (pages 951–955)

      William H. Fishman and J. H. Kreisher

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1963.tb53747.x

    2. CHARACTERIZATION OF ENZYMES IN SPECIFIC IMMUNE-PRECIPITATES (pages 956–979)

      José Uriel

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1963.tb53748.x

    3. TISSUE LOCALIZATION OF MULTIPLE FORMS OF ENZYMES, (pages 980–988)

      George W. Nace

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1963.tb53749.x

    4. PENICILLINASE-ANTIPENICILLINASE (pages 989–1005)

      M. R. Pollock

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1963.tb53750.x

    5. DISCUSSION (pages 1006–1008)

      Nathan Citri

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1963.tb53751.x

    6. IMMUNOCHEMICAL CHARACTERIZATION OF AMYLASE ISOZYMES (pages 1009–1013)

      Robert L. McGeachin

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1963.tb53752.x

    7. DISCUSSION (pages 1024–1026)

      Jack G. Makari

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1963.tb53754.x

    8. NATURALLY OCCURRING HUMAN ANTIBODIES TO STREPTOCOCCAL ENZYMES (pages 1027–1051)

      Seymour P. Halbert

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1963.tb53755.x

  11. Part VI. Antibodies as Tools in Studies of Biosynthesis of Enzymes

    1. Top of page
    2. Part I: Aspects of Two-Component Immunology
    3. Part II. Reaction Mechanisms of the Interaction of Enzymes, Antibody, and Substrate
    4. Part III. The Effect of Antibodies on Various Enzymes
    5. Part III. The Effect of Antibodyies on Various Enzymes
    6. Part III. The Effect of Antibodies on Various Enzymes
    7. DISCUSSION
    8. Part IV. Interaction of Enzyme, Coenzyme, and Substrate with Antibody A. Reaction Mechanism
    9. B. Multiple Forms of Enzymes
    10. Part V. Use of Antibodies in the Discrimination of Multiple Molecular Forms of Enzymes
    11. DISCUSSION
    12. Part VI. Antibodies as Tools in Studies of Biosynthesis of Enzymes
    13. DISCUSSION
    1. IMMUNOLOGICAL STUDIES WITH GENETICALLY ALTERED β-GALACTOSIDASES (pages 1058–1066)

      D. Perrin

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1963.tb53757.x

    2. MECHANISM OF PHOTOCHEMICAL ACCUMULATION OF REDUCED PYRIDINE NUCLEOTIDES (pages 1093–1105)

      Anthony San Pietro

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1963.tb53761.x

    3. ANTIENZYMES IN IMMUNOGENETIC STUDIES, (pages 1106–1127)

      S. R. Suskind, M. L. Wickham and M. Carsiotis

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1963.tb53762.x

  12. DISCUSSION

    1. Top of page
    2. Part I: Aspects of Two-Component Immunology
    3. Part II. Reaction Mechanisms of the Interaction of Enzymes, Antibody, and Substrate
    4. Part III. The Effect of Antibodies on Various Enzymes
    5. Part III. The Effect of Antibodyies on Various Enzymes
    6. Part III. The Effect of Antibodies on Various Enzymes
    7. DISCUSSION
    8. Part IV. Interaction of Enzyme, Coenzyme, and Substrate with Antibody A. Reaction Mechanism
    9. B. Multiple Forms of Enzymes
    10. Part V. Use of Antibodies in the Discrimination of Multiple Molecular Forms of Enzymes
    11. DISCUSSION
    12. Part VI. Antibodies as Tools in Studies of Biosynthesis of Enzymes
    13. DISCUSSION
    1. ANTIGENS IN INSECT DEVELOPMENT (pages 1137–1154)

      Hans Laufer

      Article first published online: 15 DEC 2006 | DOI: 10.1111/j.1749-6632.1963.tb53764.x

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