Annals of the New York Academy of Sciences

Cover image for Annals of the New York Academy of Sciences

July 1968

Volume 151 Pharmacogenetics

Pages 693–1000

    1. INTRODUCTORY REMARKS (page 693)

      B. N. LaDu

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1968.tb48249.x

  1. Part I. Drug Metabolism Enzymes 694-698

    1. Top of page
    2. Part I. Drug Metabolism Enzymes 694-698
    3. Part I. Drug Metabolism Enzymes 694-698
    4. Part I. Drug Metabolism Enzymes 694-698
    5. Part I. Drug Metabolism Enzymes 694-698
    6. Part I. Drug Metabolism Enzymes 694-698
    7. Part II. Hereditary Diseases of Pharmacogenetic Interest
    8. Part II. Hereditary Diseases of Pharmacogenetic Interest
    9. Part III. Genetic Variations that Modify Drug Response 887-899
    10. Part III. Genetic Variations that Modify Drug Response 887-899
    11. Part III. Genetic Variations that Modify Drug Response 887-899
    12. Part IV. Pharmacogenetics and Drug Toxicity
    13. Part IV. Pharmacogenetics and Drug Toxicity
    14. Part IV. Pharmacogenetics and Drug Toxicity
    15. Part IV. Pharmacogenetics and Drug Toxicity
    1. PHARMACOGENETICS IN ANIMALS AND MAN (pages 694–698)

      W. Kalow

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1968.tb48250.x

    2. GENETICS OF ESTERASES IN MAN (pages 699–709)

      Nancy E. Simpson

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1968.tb48251.x

    1. DISCUSSIONS OF THE PAPER (pages 708–709)

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1968.tb48252.x

  2. Part I. Drug Metabolism Enzymes 694-698

    1. Top of page
    2. Part I. Drug Metabolism Enzymes 694-698
    3. Part I. Drug Metabolism Enzymes 694-698
    4. Part I. Drug Metabolism Enzymes 694-698
    5. Part I. Drug Metabolism Enzymes 694-698
    6. Part I. Drug Metabolism Enzymes 694-698
    7. Part II. Hereditary Diseases of Pharmacogenetic Interest
    8. Part II. Hereditary Diseases of Pharmacogenetic Interest
    9. Part III. Genetic Variations that Modify Drug Response 887-899
    10. Part III. Genetic Variations that Modify Drug Response 887-899
    11. Part III. Genetic Variations that Modify Drug Response 887-899
    12. Part IV. Pharmacogenetics and Drug Toxicity
    13. Part IV. Pharmacogenetics and Drug Toxicity
    14. Part IV. Pharmacogenetics and Drug Toxicity
    15. Part IV. Pharmacogenetics and Drug Toxicity
    1. PROPERTIES OF PLASMA CHOLINESTERASE VARIANTS (pages 710–722)

      Sandra W. Clark, George A. Glaubiger and Bert N. La Du

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1968.tb48253.x

    1. DISCUSSIONS OF THE PAPER (page 722)

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1968.tb48254.x

  3. Part I. Drug Metabolism Enzymes 694-698

    1. Top of page
    2. Part I. Drug Metabolism Enzymes 694-698
    3. Part I. Drug Metabolism Enzymes 694-698
    4. Part I. Drug Metabolism Enzymes 694-698
    5. Part I. Drug Metabolism Enzymes 694-698
    6. Part I. Drug Metabolism Enzymes 694-698
    7. Part II. Hereditary Diseases of Pharmacogenetic Interest
    8. Part II. Hereditary Diseases of Pharmacogenetic Interest
    9. Part III. Genetic Variations that Modify Drug Response 887-899
    10. Part III. Genetic Variations that Modify Drug Response 887-899
    11. Part III. Genetic Variations that Modify Drug Response 887-899
    12. Part IV. Pharmacogenetics and Drug Toxicity
    13. Part IV. Pharmacogenetics and Drug Toxicity
    14. Part IV. Pharmacogenetics and Drug Toxicity
    15. Part IV. Pharmacogenetics and Drug Toxicity
    1. GENETIC VARIATIONS IN THE ACETYLATION OF ISONIAZID AND OTHER DRUGS (pages 723–733)

      David A. Price Evans

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1968.tb48255.x

    2. PURIFICATION AND PROPERTIES OF N-ACETYLTRANSFERASE FROM MAMMALIAN LIVER (pages 734–741)

      Wendell W. Weber, Sanford N. Cohen and Michael S. Steinberg

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1968.tb48256.x

    1. DISCUSS OF THE PAPER (pages 751–752)

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1968.tb48258.x

  4. Part I. Drug Metabolism Enzymes 694-698

    1. Top of page
    2. Part I. Drug Metabolism Enzymes 694-698
    3. Part I. Drug Metabolism Enzymes 694-698
    4. Part I. Drug Metabolism Enzymes 694-698
    5. Part I. Drug Metabolism Enzymes 694-698
    6. Part I. Drug Metabolism Enzymes 694-698
    7. Part II. Hereditary Diseases of Pharmacogenetic Interest
    8. Part II. Hereditary Diseases of Pharmacogenetic Interest
    9. Part III. Genetic Variations that Modify Drug Response 887-899
    10. Part III. Genetic Variations that Modify Drug Response 887-899
    11. Part III. Genetic Variations that Modify Drug Response 887-899
    12. Part IV. Pharmacogenetics and Drug Toxicity
    13. Part IV. Pharmacogenetics and Drug Toxicity
    14. Part IV. Pharmacogenetics and Drug Toxicity
    15. Part IV. Pharmacogenetics and Drug Toxicity
    1. HEMOLYSIS DUE TO INHERITED ERYTHROCYTE ENZYME DEFICIENCIES (pages 765–776)

      Paul E. Carson

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1968.tb48260.x

    2. HEREDITARY METHEMOGLOBINEMIA, TOXIC METHEMOGLOBINEMIA AND THE REDUCTION OF METHEMOGLOBIN (pages 795–806)

      Ernst R. Jaffé and Gertrude Neumann

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1968.tb48262.x

    1. DISCUSS OF THE PAPER (page 806)

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1968.tb48263.x

  5. Part I. Drug Metabolism Enzymes 694-698

    1. Top of page
    2. Part I. Drug Metabolism Enzymes 694-698
    3. Part I. Drug Metabolism Enzymes 694-698
    4. Part I. Drug Metabolism Enzymes 694-698
    5. Part I. Drug Metabolism Enzymes 694-698
    6. Part I. Drug Metabolism Enzymes 694-698
    7. Part II. Hereditary Diseases of Pharmacogenetic Interest
    8. Part II. Hereditary Diseases of Pharmacogenetic Interest
    9. Part III. Genetic Variations that Modify Drug Response 887-899
    10. Part III. Genetic Variations that Modify Drug Response 887-899
    11. Part III. Genetic Variations that Modify Drug Response 887-899
    12. Part IV. Pharmacogenetics and Drug Toxicity
    13. Part IV. Pharmacogenetics and Drug Toxicity
    14. Part IV. Pharmacogenetics and Drug Toxicity
    15. Part IV. Pharmacogenetics and Drug Toxicity
    1. DRUGS, ANESTHESIA AND ABNORMAL HEMOGLOBINS (pages 807–821)

      A. G. Motulsky and G. Stamatoyannopoulos

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1968.tb48264.x

    2. DISCSSION OF THE PAPER (pages 820–821)

      Dr. E. R. Jaffe

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1968.tb48265.x

    3. ACETOPHENETIDIN-INDUCED METHEMOGLOBINEMIA (pages 822–832)

      N. T. Shahidi

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1968.tb48266.x

  6. Part II. Hereditary Diseases of Pharmacogenetic Interest

    1. Top of page
    2. Part I. Drug Metabolism Enzymes 694-698
    3. Part I. Drug Metabolism Enzymes 694-698
    4. Part I. Drug Metabolism Enzymes 694-698
    5. Part I. Drug Metabolism Enzymes 694-698
    6. Part I. Drug Metabolism Enzymes 694-698
    7. Part II. Hereditary Diseases of Pharmacogenetic Interest
    8. Part II. Hereditary Diseases of Pharmacogenetic Interest
    9. Part III. Genetic Variations that Modify Drug Response 887-899
    10. Part III. Genetic Variations that Modify Drug Response 887-899
    11. Part III. Genetic Variations that Modify Drug Response 887-899
    12. Part IV. Pharmacogenetics and Drug Toxicity
    13. Part IV. Pharmacogenetics and Drug Toxicity
    14. Part IV. Pharmacogenetics and Drug Toxicity
    15. Part IV. Pharmacogenetics and Drug Toxicity
    1. GENETIC FACTORS RELATED TO GLAUCOMA (pages 861–874)

      Mansour F. Armaly

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1968.tb48270.x

    1. DISCUSSION OF THE PAPER (page 874)

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1968.tb48271.x

  7. Part II. Hereditary Diseases of Pharmacogenetic Interest

    1. Top of page
    2. Part I. Drug Metabolism Enzymes 694-698
    3. Part I. Drug Metabolism Enzymes 694-698
    4. Part I. Drug Metabolism Enzymes 694-698
    5. Part I. Drug Metabolism Enzymes 694-698
    6. Part I. Drug Metabolism Enzymes 694-698
    7. Part II. Hereditary Diseases of Pharmacogenetic Interest
    8. Part II. Hereditary Diseases of Pharmacogenetic Interest
    9. Part III. Genetic Variations that Modify Drug Response 887-899
    10. Part III. Genetic Variations that Modify Drug Response 887-899
    11. Part III. Genetic Variations that Modify Drug Response 887-899
    12. Part IV. Pharmacogenetics and Drug Toxicity
    13. Part IV. Pharmacogenetics and Drug Toxicity
    14. Part IV. Pharmacogenetics and Drug Toxicity
    15. Part IV. Pharmacogenetics and Drug Toxicity
    1. ALTERED DRUG RESPONSE IN FAMILIAL DYSAUTONOMIA (pages 876–879)

      Joseph Dancis

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1968.tb48272.x

  8. Part III. Genetic Variations that Modify Drug Response 887-899

    1. Top of page
    2. Part I. Drug Metabolism Enzymes 694-698
    3. Part I. Drug Metabolism Enzymes 694-698
    4. Part I. Drug Metabolism Enzymes 694-698
    5. Part I. Drug Metabolism Enzymes 694-698
    6. Part I. Drug Metabolism Enzymes 694-698
    7. Part II. Hereditary Diseases of Pharmacogenetic Interest
    8. Part II. Hereditary Diseases of Pharmacogenetic Interest
    9. Part III. Genetic Variations that Modify Drug Response 887-899
    10. Part III. Genetic Variations that Modify Drug Response 887-899
    11. Part III. Genetic Variations that Modify Drug Response 887-899
    12. Part IV. Pharmacogenetics and Drug Toxicity
    13. Part IV. Pharmacogenetics and Drug Toxicity
    14. Part IV. Pharmacogenetics and Drug Toxicity
    15. Part IV. Pharmacogenetics and Drug Toxicity
    1. VARIATIONS IN DETOXICATION ENZYMES DURING MAMMALIAN DEVELOPMENT (pages 887–899)

      Sumner J. Yaffe, Joseph Krasner and Charlotte S. Catz

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1968.tb48274.x

    1. DISCUSSION OF THE PAPER (page 912)

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1968.tb48276.x

  9. Part III. Genetic Variations that Modify Drug Response 887-899

    1. Top of page
    2. Part I. Drug Metabolism Enzymes 694-698
    3. Part I. Drug Metabolism Enzymes 694-698
    4. Part I. Drug Metabolism Enzymes 694-698
    5. Part I. Drug Metabolism Enzymes 694-698
    6. Part I. Drug Metabolism Enzymes 694-698
    7. Part II. Hereditary Diseases of Pharmacogenetic Interest
    8. Part II. Hereditary Diseases of Pharmacogenetic Interest
    9. Part III. Genetic Variations that Modify Drug Response 887-899
    10. Part III. Genetic Variations that Modify Drug Response 887-899
    11. Part III. Genetic Variations that Modify Drug Response 887-899
    12. Part IV. Pharmacogenetics and Drug Toxicity
    13. Part IV. Pharmacogenetics and Drug Toxicity
    14. Part IV. Pharmacogenetics and Drug Toxicity
    15. Part IV. Pharmacogenetics and Drug Toxicity
    1. HEREDITARY RESISTANCE TO COUMARIN ANTICOAGULANT DRUGS IN MAN AND RAT (pages 913–931)

      Robert A. O'Reilly, Judith G. Pool and Paul M. Aggeler†

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1968.tb48277.x

    1. COMMENT SUBSEQUENT TO THE CONFERENCE (page 931)

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1968.tb48278.x

  10. Part III. Genetic Variations that Modify Drug Response 887-899

    1. Top of page
    2. Part I. Drug Metabolism Enzymes 694-698
    3. Part I. Drug Metabolism Enzymes 694-698
    4. Part I. Drug Metabolism Enzymes 694-698
    5. Part I. Drug Metabolism Enzymes 694-698
    6. Part I. Drug Metabolism Enzymes 694-698
    7. Part II. Hereditary Diseases of Pharmacogenetic Interest
    8. Part II. Hereditary Diseases of Pharmacogenetic Interest
    9. Part III. Genetic Variations that Modify Drug Response 887-899
    10. Part III. Genetic Variations that Modify Drug Response 887-899
    11. Part III. Genetic Variations that Modify Drug Response 887-899
    12. Part IV. Pharmacogenetics and Drug Toxicity
    13. Part IV. Pharmacogenetics and Drug Toxicity
    14. Part IV. Pharmacogenetics and Drug Toxicity
    15. Part IV. Pharmacogenetics and Drug Toxicity
    1. VARIATIONS IN METABOLISM OF COUMARIN ANTICOAGULANT DRUGS (pages 932–935)

      Harvey M. Solomon

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1968.tb48279.x

    2. ATYPICAL HUMAN LIVER ALCOHOL DEHYDROGENASE (pages 936–946)

      I. P. von Wartburg and P. M. Schürch

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1968.tb48280.x

    3. HYPERRIGIDITY AND HYPERTHERMIA ASSOCIATED WITH ANESTHESIA (pages 947–958)

      B. A. Britt and W. Kalow

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1968.tb48281.x

  11. Part IV. Pharmacogenetics and Drug Toxicity

    1. Top of page
    2. Part I. Drug Metabolism Enzymes 694-698
    3. Part I. Drug Metabolism Enzymes 694-698
    4. Part I. Drug Metabolism Enzymes 694-698
    5. Part I. Drug Metabolism Enzymes 694-698
    6. Part I. Drug Metabolism Enzymes 694-698
    7. Part II. Hereditary Diseases of Pharmacogenetic Interest
    8. Part II. Hereditary Diseases of Pharmacogenetic Interest
    9. Part III. Genetic Variations that Modify Drug Response 887-899
    10. Part III. Genetic Variations that Modify Drug Response 887-899
    11. Part III. Genetic Variations that Modify Drug Response 887-899
    12. Part IV. Pharmacogenetics and Drug Toxicity
    13. Part IV. Pharmacogenetics and Drug Toxicity
    14. Part IV. Pharmacogenetics and Drug Toxicity
    15. Part IV. Pharmacogenetics and Drug Toxicity
    1. DISCUSSION OF THE PAPER (page 967)

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1968.tb48283.x

  12. Part IV. Pharmacogenetics and Drug Toxicity

    1. Top of page
    2. Part I. Drug Metabolism Enzymes 694-698
    3. Part I. Drug Metabolism Enzymes 694-698
    4. Part I. Drug Metabolism Enzymes 694-698
    5. Part I. Drug Metabolism Enzymes 694-698
    6. Part I. Drug Metabolism Enzymes 694-698
    7. Part II. Hereditary Diseases of Pharmacogenetic Interest
    8. Part II. Hereditary Diseases of Pharmacogenetic Interest
    9. Part III. Genetic Variations that Modify Drug Response 887-899
    10. Part III. Genetic Variations that Modify Drug Response 887-899
    11. Part III. Genetic Variations that Modify Drug Response 887-899
    12. Part IV. Pharmacogenetics and Drug Toxicity
    13. Part IV. Pharmacogenetics and Drug Toxicity
    14. Part IV. Pharmacogenetics and Drug Toxicity
    15. Part IV. Pharmacogenetics and Drug Toxicity
    1. PHARMACOGENETICS IN THE DETECTION OF THE HYPERSUSCEPTIBLE WORKER (pages 968–976)

      H. E. Stokinger, J. T. Mountain and L. D. Scheel

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1968.tb48284.x

    1. DISCUSSION OF THE PAPER (pages 975–976)

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1968.tb48285.x

  13. Part IV. Pharmacogenetics and Drug Toxicity

    1. Top of page
    2. Part I. Drug Metabolism Enzymes 694-698
    3. Part I. Drug Metabolism Enzymes 694-698
    4. Part I. Drug Metabolism Enzymes 694-698
    5. Part I. Drug Metabolism Enzymes 694-698
    6. Part I. Drug Metabolism Enzymes 694-698
    7. Part II. Hereditary Diseases of Pharmacogenetic Interest
    8. Part II. Hereditary Diseases of Pharmacogenetic Interest
    9. Part III. Genetic Variations that Modify Drug Response 887-899
    10. Part III. Genetic Variations that Modify Drug Response 887-899
    11. Part III. Genetic Variations that Modify Drug Response 887-899
    12. Part IV. Pharmacogenetics and Drug Toxicity
    13. Part IV. Pharmacogenetics and Drug Toxicity
    14. Part IV. Pharmacogenetics and Drug Toxicity
    15. Part IV. Pharmacogenetics and Drug Toxicity
    1. DRUG-INDUCED CHROMOSOMAL ABERRATIONS (pages 977–987)

      Kurt Hirschhorn and Maimon M. Cohen

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1968.tb48286.x

    1. DISCUSSION OF THE PAPER (page 987)

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1968.tb48287.x

  14. Part IV. Pharmacogenetics and Drug Toxicity

    1. Top of page
    2. Part I. Drug Metabolism Enzymes 694-698
    3. Part I. Drug Metabolism Enzymes 694-698
    4. Part I. Drug Metabolism Enzymes 694-698
    5. Part I. Drug Metabolism Enzymes 694-698
    6. Part I. Drug Metabolism Enzymes 694-698
    7. Part II. Hereditary Diseases of Pharmacogenetic Interest
    8. Part II. Hereditary Diseases of Pharmacogenetic Interest
    9. Part III. Genetic Variations that Modify Drug Response 887-899
    10. Part III. Genetic Variations that Modify Drug Response 887-899
    11. Part III. Genetic Variations that Modify Drug Response 887-899
    12. Part IV. Pharmacogenetics and Drug Toxicity
    13. Part IV. Pharmacogenetics and Drug Toxicity
    14. Part IV. Pharmacogenetics and Drug Toxicity
    15. Part IV. Pharmacogenetics and Drug Toxicity
    1. GENETIC FACTORS IN HYPERSENSITIVITY REACTIONS TO DRUGS (pages 988–996)

      Bernard B. Levine

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1968.tb48288.x

    2. TERATOLOGY AND PHARMACOGENETICS (pages 997–1000)

      Harold Kalter

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1968.tb48289.x

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