Annals of the New York Academy of Sciences

Cover image for Annals of the New York Academy of Sciences

June 1973

Volume 212 Multienzyme Systems in Endocrinology: Progress in Purification and Methods of Investigation

Pages 3–468

  1. Article

    1. Top of page
    2. Article
    3. PART I. SUBCELLULAR SITES AND MECHANISMS OF MIXED-FUNCTION OXIDASES
    4. PART II. RECENT TECHNIQUES FOR STUDY OF MIXED-FUNCTION OXIDASES
    5. PART III. MIXED-FUNCTION OXIDASES OF THE LIVEK AND PEROXIDASES OF THE THYROID GLAND
    6. PART IV. MIXED-FUNCTION OXIDASES OF THE ADRENAL CORTEX
    7. PART V. MIXED-FUNCTION OXIDASES OF THE OVARY AND TESTIS
    1. INTRODUCTORY REMARKS (page 3)

      David Y. Cooper

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1973.tb47581.x

  2. PART I. SUBCELLULAR SITES AND MECHANISMS OF MIXED-FUNCTION OXIDASES

    1. Top of page
    2. Article
    3. PART I. SUBCELLULAR SITES AND MECHANISMS OF MIXED-FUNCTION OXIDASES
    4. PART II. RECENT TECHNIQUES FOR STUDY OF MIXED-FUNCTION OXIDASES
    5. PART III. MIXED-FUNCTION OXIDASES OF THE LIVEK AND PEROXIDASES OF THE THYROID GLAND
    6. PART IV. MIXED-FUNCTION OXIDASES OF THE ADRENAL CORTEX
    7. PART V. MIXED-FUNCTION OXIDASES OF THE OVARY AND TESTIS
    1. OXENOID MODELS FOR ENZYMIC HYDROXYLATIONS (pages 4–12)

      Gordon A. Hamilton, Jack R. Giacin, Thomas M. Hellman, Maurice E. Snook and Jonathan W. Weller

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1973.tb47582.x

    2. FLAVIN-O2 INTERACTION MECHANISMS AND THE FUNCTION OF FLAVIN IN HYDROXYLATION REACTIONS (pages 13–26)

      P. Hemmerich and F. Muller

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1973.tb47583.x

    3. DRUGS, ALCOHOL AND SEX HORMONES: A MOLECULAR PERSPECTIVE OF THE RECEPTIVITY OF CYTOCHROME P-450 (pages 27–49)

      Ronald W. Estabrook, J. Ian Mason, Jeffrey Baron, David Lambeth and Michael Waterman

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1973.tb47584.x

  3. PART II. RECENT TECHNIQUES FOR STUDY OF MIXED-FUNCTION OXIDASES

    1. Top of page
    2. Article
    3. PART I. SUBCELLULAR SITES AND MECHANISMS OF MIXED-FUNCTION OXIDASES
    4. PART II. RECENT TECHNIQUES FOR STUDY OF MIXED-FUNCTION OXIDASES
    5. PART III. MIXED-FUNCTION OXIDASES OF THE LIVEK AND PEROXIDASES OF THE THYROID GLAND
    6. PART IV. MIXED-FUNCTION OXIDASES OF THE ADRENAL CORTEX
    7. PART V. MIXED-FUNCTION OXIDASES OF THE OVARY AND TESTIS
    1. GENERAL DISCUSSION (pages 50–56)

      I. C. Gunsalus

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1973.tb47585.x

    2. STUDIES ON THE FUNCTION OF ADRENODOXIN AND TPNH-CYTOCHROME C REDUCTASE IN THE MITOCHONDRIA AND MICROSOMES OF ADRENAL CORTEX, UTILIZING IMMUNOCHEMICAL TECHNIQUES (pages 76–88)

      Bettie Sue Siler Masters, Wayne E. Taylor, Elizabeth L. Isaacson, Jeffrey Baron, J. B. Harkins, George T. Bryan and Edward B. Nelson

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1973.tb47587.x

    3. STUDIES ON THE NADPH OXIDASE REACTION OF NADPH-CYTOCHROME C REDUCTASE. I. THE ROLE OF SUPEROXIDE ANION (pages 89–93)

      Russell A. Prough and Bettie Sue Siler Masters

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1973.tb47588.x

    4. CYTOCHROME P-450***am SUBSTRATE AND EFFECTOR INTERACTIONS (pages 107–121)

      I. C. Gunsalus, J. D. Lipscomb and J. R. Meeks

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1973.tb47590.x

  4. PART III. MIXED-FUNCTION OXIDASES OF THE LIVEK AND PEROXIDASES OF THE THYROID GLAND

    1. Top of page
    2. Article
    3. PART I. SUBCELLULAR SITES AND MECHANISMS OF MIXED-FUNCTION OXIDASES
    4. PART II. RECENT TECHNIQUES FOR STUDY OF MIXED-FUNCTION OXIDASES
    5. PART III. MIXED-FUNCTION OXIDASES OF THE LIVEK AND PEROXIDASES OF THE THYROID GLAND
    6. PART IV. MIXED-FUNCTION OXIDASES OF THE ADRENAL CORTEX
    7. PART V. MIXED-FUNCTION OXIDASES OF THE OVARY AND TESTIS
    1. INVESTIGATION OF THE MULTIENZYMIC SYSTEM OF MICROSOMAL CHOLESTEROL BIOSYNTHESIS (pages 122–138)

      James L. Gaylor and Constance V. Delwiche

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1973.tb47591.x

    2. BILE ACID FORMATION BY LIVER MICROSOMAL SYSTEMS (pages 139–147)

      Helmut Greim, Dietmar Trülzsch, Peter Czygan, Ferenc Hutterer, Fenton Schaffner, Hans Popper, David Y. Cooper and Otto Rosenthal

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1973.tb47592.x

    3. DRUG-INDUCED ALTERATIONS OF STEROID HORMONE METABOLISM IN MAN (pages 148–155)

      H. Leon Bradlow, Barnett Zumoff, D. K. Fukushima, Leon Hellman, David R. Bickers, Alvito P. Alvares and Attallah Kappas

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1973.tb47593.x

    4. THE ROLE OF CYTOCHROME P-450 AND P-448 IN DRUG AND STEROID HYDROXYLATIONS (pages 156–174)

      Anthony Y. H. Lu, Wayne Levin, Susan West, Martin Jacobson, Dene Ryan, Ronald Kuntzman and A. H. Conney

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1973.tb47594.x

    5. BIOCHEMICAL STUDIES ON THYROID PEROXIDASE: SOLUBI-LIZATION BY NON-PROTEOLYTIC METHODS (pages 183–194)

      J. T. Neary, B. Davidson, F. Maloof and M. Soodak

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1973.tb47596.x

  5. PART IV. MIXED-FUNCTION OXIDASES OF THE ADRENAL CORTEX

    1. Top of page
    2. Article
    3. PART I. SUBCELLULAR SITES AND MECHANISMS OF MIXED-FUNCTION OXIDASES
    4. PART II. RECENT TECHNIQUES FOR STUDY OF MIXED-FUNCTION OXIDASES
    5. PART III. MIXED-FUNCTION OXIDASES OF THE LIVEK AND PEROXIDASES OF THE THYROID GLAND
    6. PART IV. MIXED-FUNCTION OXIDASES OF THE ADRENAL CORTEX
    7. PART V. MIXED-FUNCTION OXIDASES OF THE OVARY AND TESTIS
    1. PREPARATION AND PROPERTIES OF MITOCHONDRIAL CYTOCHROME P-450 FROM BOVINE ADRENAL CORTEX (pages 208–226)

      Fumiko Mitani, Noriko Ando and Shigeo Horie

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1973.tb47598.x

    2. STUDIES ON THE PARTIALLY PURIFIED HEME PROTEIN P-450 FROM THE ADRENAL CORTEX (pages 227–242)

      D. Y. Cooper, H. Schleyer, O. Rosenthal and S. S. Levin

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1973.tb47599.x

    3. THE DETECTION OF DIFFERENT STATES OF THE P-450 CYTOCHROMES IN ADRENAL MITOCHONDRIA; CHANGES INDUCED BY ACTH (pages 243–261)

      C. R. Jefcoate, E. R. Simpson, G. S. Boyd, A. C. Brownie and W. H. Orme-Johnson

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1973.tb47600.x

    4. KINETIC STUDIES ON THE MECHANISM OF CONVERSION OF CHOLESTEROL TO PREGNENOLONE (pages 262–275)

      Shlomo Burstein and Marcel Gut

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1973.tb47601.x

    5. ACTIVATOR AND INHIBITOR FACTORS IN CHOLESTEROL SIDE-CHAIN CLEAVAGE (pages 276–289)

      Frank Ungar, Kenneth W. Kan and Kim E. McCoy

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1973.tb47602.x

    6. CONTROL OF SUBSTRATE FLUX AND ADRENAL CYTOCHROME P-450 (pages 290–306)

      J. J. Bell, S. C. Cheng and B. W. Harding

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1973.tb47603.x

    7. THE IN VIVO EFFECT OF ACTH ON UTILIZATION OF REDUCING ENERGY FOR PREGNENOLONE SYNTHESIS BY ADRENAL MITOCHONDRIA (pages 307–318)

      L. R. Johnson, A. Ruhmann-Wennhold and D. H. Nelson

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1973.tb47604.x

    8. LIFETIME OF ADRENAL CYTOCHROME P-450 AS INFLUENCED BY ACTH (pages 319–343)

      J. L. Purvis, J. A. Canick, J. I. Mason, R. W. Estabrook and J.L. McCarthy

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1973.tb47605.x

    9. EFFECT OF ACTH ON ADRENAL MITOCHONDRIAL CYTOCHROME P-450 IN THE RAT (pages 344–360)

      Alexander C. Brownie, Josephine Alfano, Colin R. Jefcoate, William Orme-Johnson, Helmut Beinert and Evan R. Simpson

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1973.tb47606.x

    10. CHOLESTEROL METABOLISM IN THE ADRENAL CORTEX: STUDIES ON THE MODE OF ACTION OF ACTH (pages 361–377)

      G. S. Boyd and W. H. Trzeciak

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1973.tb47607.x

    11. STUDIES ON THE AROMATIZATION OF C-19 ANDROGENS (pages 378–391)

      E. Aubrey Thompson and Pentti K. Siiteri

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1973.tb47608.x

  6. PART V. MIXED-FUNCTION OXIDASES OF THE OVARY AND TESTIS

    1. Top of page
    2. Article
    3. PART I. SUBCELLULAR SITES AND MECHANISMS OF MIXED-FUNCTION OXIDASES
    4. PART II. RECENT TECHNIQUES FOR STUDY OF MIXED-FUNCTION OXIDASES
    5. PART III. MIXED-FUNCTION OXIDASES OF THE LIVEK AND PEROXIDASES OF THE THYROID GLAND
    6. PART IV. MIXED-FUNCTION OXIDASES OF THE ADRENAL CORTEX
    7. PART V. MIXED-FUNCTION OXIDASES OF THE OVARY AND TESTIS
    1. COMPARATIVE STUDIES ON MITOCHONDRIAL AND PARTIALLY PURIFIED BOVINE CORPUS LUTEUM CYTOCHROME P-450 (pages 392–405)

      E. N. McIntosh, F. Mitani, V. I. Užgiris, H. A. Salhanick and C. Alonso

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1973.tb47609.x

    2. TESTICULAR CYTOCHROME P-450 AND IRON-SULFUR PROTEIN AS RELATED TO STEROID METABOLISM (pages 406–419)

      J. Ian Mason, Ronald W. Estabrook and John L. Purvis

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1973.tb47610.x

    3. THE MITOCHONDRIAL ROLE IN HEPATIC CELL MIXED-FUNCTION OXIDATIONS (pages 420–427)

      John B. Schenkman, Dominick L. Cinti and Peter Moldeus

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1973.tb47611.x

    4. BIOCHEMICAL STUDIES ON CYTOCHROME P-450 SOLUBILIZED FROM LIVER MICROSOMES: PARTIAL PURIFICATION AND MECHANISM OF CATALYSIS (pages 449–457)

      Minor J. Coon, Robert M. Kaschnitz, Henry W. Strobel and Theodore A. van der Hoeven

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1973.tb47613.x

    5. GENERAL DISCUSSION (pages 463–468)

      David Y. Cooper

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1973.tb47615.x

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