Annals of the New York Academy of Sciences

Cover image for Annals of the New York Academy of Sciences

January 1975

Volume 246 Toxicity of Vinyl Chloride-Polyvinyl Chloride

Pages 4–337

    1. ACKNOWLEDGMENTS (page 4)

      Irving J. Selikoff and E. Cuyler Hammond

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb51074.x

    2. INTRODUCTORY REMARKS (page 5)

      Marcus M. Key

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb51075.x

  1. Part I. Toxicological Investigations of Vinyl Chloride-Polyvinyl Chloride A. Clinical Studies

    1. Top of page
    2. Part I. Toxicological Investigations of Vinyl Chloride-Polyvinyl Chloride A. Clinical Studies
    3. Part I. Toxicological Investigations of Vinyl Chloride-Polyvinyl Chloride B. Experimental Studies
    4. Part I. Toxicological Investigations of Vinyl Chloride-Polyvinyl Chloride C. Pathology
    5. Part I. Toxicological Investigations of Vinyl Chloride-Polyvinyl Chloride A. Experimental Studies
    6. Part I. Toxicological Investigations of Vinyl Chloride-Polyvinyl Chloride B. Epidemiological Studies
    7. Part I. Toxicological Investigations of Vinyl Chloride-Polyvinyl Chloride C. Pathology
    8. Part III. Environmental Considerations
    9. Part IV. Control and Management
    1. CLINICAL MANIFESTATIONS AND COURSE OF VINYL CHLORIDE DISEASE (pages 6–17)

      G. Veltman, C.-E. Lange, S. Jühe, G. Stein and U. Bachner

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb51076.x

    2. FURTHER RESULTS IN POLYVINYL CHLORIDE PRODUCTION WORKERS (pages 18–21)

      C.-E. Lange, S. Jühe, G. Stein and G. Veltman

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb51077.x

    3. PREVALENCE OF DISEASE AMONG VINYL CHLORIDE AND POLYVINYL CHLORIDE WORKERS (pages 22–41)

      Ruth Lilis, Henry Anderson, William J. Nicholson, Susan Daum, Alf S. Fischbein and Irving J. Selikoff

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb51078.x

    4. CHANGES IN PULMONARY FUNCTION IN WORKERS EXPOSED TO VINYL CHLORIDE AND POLYVINYL CHLORIDE (pages 42–52)

      Albert Miller, Alvin S. Teirstein, Ming Chuang, Irving J. Selikoff and Raphael Warshaw

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb51079.x

    5. CLINICAL MANIFESTATIONS IN VINYL CHLORIDE POISONING (pages 53–69)

      I. Suciu, L. Prodan, Elena Ilea, A. Păduraru and Livia Pascu

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb51080.x

    6. PERSISTENCE OF VINYL CHLORIDE-INDUCED LIVER INJURY AFTER CESSATION OF EXPOSURE (pages 70–77)

      Paul D. Berk, James F. Martin and Jeanne G. Waggoner

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb51081.x

    7. BONE LESIONS AMONG POLYVINYL CHLORIDE PRODUCTION WORKERS IN JAPAN (pages 78–79)

      Hiroyuki Sakabe

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb51082.x

    8. AN EPIDEMIOLOGIC STUDY OF BLOOD SCREENING TESTS AND ILLNESS HISTORIES AMONG CHEMICAL WORKERS INVOLVED IN THE MANUFACTURE OF POLYVINYL CHLORIDE (pages 80–87)

      Robert H. Wyatt, Jane M. Kotchen, Donald L. Hochstrasser, Jack W. Buchanan Jr., Duncan R. Campbell, Joseph C. Slaughter and Alphonse H. Doll

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb51083.x

    9. LIVER DISEASE AMONG POLYVINYL CHLORIDE PRODUCTION WORKERS (pages 88–94)

      John L. Creech Jr. and Laszlo Makk

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb51084.x

    10. UNUSUAL SPLENOMEGALIC LIVER DISEASE AS EVIDENCED BY PERITONEOSCOPY AND GUIDED LIVER BIOPSY AMONG POLYVINYL CHLORIDE PRODUCTION WORKERS (pages 95–134)

      H. J. Marsteller, W. K. Lelbach, R. Müller and P. Gedigk

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb51085.x

  2. Part I. Toxicological Investigations of Vinyl Chloride-Polyvinyl Chloride B. Experimental Studies

    1. Top of page
    2. Part I. Toxicological Investigations of Vinyl Chloride-Polyvinyl Chloride A. Clinical Studies
    3. Part I. Toxicological Investigations of Vinyl Chloride-Polyvinyl Chloride B. Experimental Studies
    4. Part I. Toxicological Investigations of Vinyl Chloride-Polyvinyl Chloride C. Pathology
    5. Part I. Toxicological Investigations of Vinyl Chloride-Polyvinyl Chloride A. Experimental Studies
    6. Part I. Toxicological Investigations of Vinyl Chloride-Polyvinyl Chloride B. Epidemiological Studies
    7. Part I. Toxicological Investigations of Vinyl Chloride-Polyvinyl Chloride C. Pathology
    8. Part III. Environmental Considerations
    9. Part IV. Control and Management
    1. PRELIMINARY STUDIES OF THE FATE OF INHALED VINYL CHLORIDE MONOMER IN RATS (pages 135–148)

      R. E. Hefner Jr., P. G. Watanabe and P. J. Gehring

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb51086.x

    2. DISCUSSION OF PRECEDING PAPER (page 149)

      Gerald Oster

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb51087.x

    3. A PROCEDURE FOR PREPARING 14C-LABELED VINYL CHLORIDE (pages 152–153)

      Eugene R. Wagner and Wesley W. Muelder

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb51089.x

    4. EXPERIMENTAL ACUTE TOXICITY OF VINYL CHLORIDE (MONOCHLOROETHENE) (pages 154–158)

      Leon Prodan, I. Suciu, V. Pîslaru, Elena Ilea and Livia Pascu

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb51090.x

    5. EXPERIMENTAL CHRONIC POISONING WITH VINYL CHLORIDE (MONOCHLOROETHENE) (pages 159–163)

      Leon Prodan, I. Suciu, V. Pîslaru, Elena Ilea and Livia Pascu

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb51091.x

    6. HEMATOGENOUS DISSEMINATION OF INGESTED POLYVINYL CHLORIDE PARTICLES (pages 164–171)

      Gerhard Volkheimer

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb51092.x

  3. Part I. Toxicological Investigations of Vinyl Chloride-Polyvinyl Chloride C. Pathology

    1. Top of page
    2. Part I. Toxicological Investigations of Vinyl Chloride-Polyvinyl Chloride A. Clinical Studies
    3. Part I. Toxicological Investigations of Vinyl Chloride-Polyvinyl Chloride B. Experimental Studies
    4. Part I. Toxicological Investigations of Vinyl Chloride-Polyvinyl Chloride C. Pathology
    5. Part I. Toxicological Investigations of Vinyl Chloride-Polyvinyl Chloride A. Experimental Studies
    6. Part I. Toxicological Investigations of Vinyl Chloride-Polyvinyl Chloride B. Epidemiological Studies
    7. Part I. Toxicological Investigations of Vinyl Chloride-Polyvinyl Chloride C. Pathology
    8. Part III. Environmental Considerations
    9. Part IV. Control and Management
    1. ALTERATIONS OF LIVER AND SPLEEN AMONG WORKERS EXPOSED TO VINYL CHLORIDE (pages 172–194)

      Hans Popper and Louis B. Thomas

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb51093.x

  4. Part I. Toxicological Investigations of Vinyl Chloride-Polyvinyl Chloride A. Experimental Studies

    1. Top of page
    2. Part I. Toxicological Investigations of Vinyl Chloride-Polyvinyl Chloride A. Clinical Studies
    3. Part I. Toxicological Investigations of Vinyl Chloride-Polyvinyl Chloride B. Experimental Studies
    4. Part I. Toxicological Investigations of Vinyl Chloride-Polyvinyl Chloride C. Pathology
    5. Part I. Toxicological Investigations of Vinyl Chloride-Polyvinyl Chloride A. Experimental Studies
    6. Part I. Toxicological Investigations of Vinyl Chloride-Polyvinyl Chloride B. Epidemiological Studies
    7. Part I. Toxicological Investigations of Vinyl Chloride-Polyvinyl Chloride C. Pathology
    8. Part III. Environmental Considerations
    9. Part IV. Control and Management
    1. CARCINOGENICITY BIOASSAYS OF VINYL CHLORIDE: CURRENT RESULTS (pages 195–218)

      Cesare Maltoni and Giuseppe Lefemine

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb51094.x

    2. INTERIM RESULTS OF EXPOSURE OF RATS, HAMSTERS, AND MICE TO VINYL CHLORIDE (pages 219–224)

      M. L. Keplinger, J. W. Goode, D. E. Gordon and J. C. Calandra

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb51095.x

  5. Part I. Toxicological Investigations of Vinyl Chloride-Polyvinyl Chloride B. Epidemiological Studies

    1. Top of page
    2. Part I. Toxicological Investigations of Vinyl Chloride-Polyvinyl Chloride A. Clinical Studies
    3. Part I. Toxicological Investigations of Vinyl Chloride-Polyvinyl Chloride B. Experimental Studies
    4. Part I. Toxicological Investigations of Vinyl Chloride-Polyvinyl Chloride C. Pathology
    5. Part I. Toxicological Investigations of Vinyl Chloride-Polyvinyl Chloride A. Experimental Studies
    6. Part I. Toxicological Investigations of Vinyl Chloride-Polyvinyl Chloride B. Epidemiological Studies
    7. Part I. Toxicological Investigations of Vinyl Chloride-Polyvinyl Chloride C. Pathology
    8. Part III. Environmental Considerations
    9. Part IV. Control and Management
    1. MORTALITY EXPERIENCE OF A COHORT OF VINYL CHLORIDE-POLYVINYL CHLORIDE WORKERS (pages 225–230)

      William J. Nicholson, E. Cuyler Hammond, Herbert Seidman and Irving J. Selikoff

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb51096.x

    2. CHARACTERISTICS OF CASES OF ANGIOSARCOMA OF THE LIVER AMONG VINYL CHLORIDE WORKERS IN THE UNITED STATES (pages 231–236)

      Clark W. Heath Jr., Henry Falk and John L. Creech Jr.

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb51097.x

    3. FROM MOUSE TO MAN—OR HOW TO GET FROM THE LABORATORY TO PARK AVENUE AND 59TH STREET (pages 237–248)

      Marvin A. Schneiderman, Nathan Mantel and Charles C. Brown

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb51098.x

    4. TWO POSSIBLE CASES OF ANGIOSARCOMA OF THE LIVER IN A GROUP OF SWEDISH VINYL CHLORIDE-POLYVINYL CHLORIDE WORKERS (pages 249–250)

      David Byrén and Bo Holmberg

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb51099.x

    5. COMMENTS FOR OPENING OF DISCUSSION ON “NEOPLASTIC EFFECTS” (pages 251–257)

      Thomas F. Mancuso

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb51100.x

    6. ON THE POSSIBLE MECHANISM OF CARCINOGENIC ACTION OF VINYL CHLORIDE (pages 258–267)

      Benjamin L. Van Duuren

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb51101.x

  6. Part I. Toxicological Investigations of Vinyl Chloride-Polyvinyl Chloride C. Pathology

    1. Top of page
    2. Part I. Toxicological Investigations of Vinyl Chloride-Polyvinyl Chloride A. Clinical Studies
    3. Part I. Toxicological Investigations of Vinyl Chloride-Polyvinyl Chloride B. Experimental Studies
    4. Part I. Toxicological Investigations of Vinyl Chloride-Polyvinyl Chloride C. Pathology
    5. Part I. Toxicological Investigations of Vinyl Chloride-Polyvinyl Chloride A. Experimental Studies
    6. Part I. Toxicological Investigations of Vinyl Chloride-Polyvinyl Chloride B. Epidemiological Studies
    7. Part I. Toxicological Investigations of Vinyl Chloride-Polyvinyl Chloride C. Pathology
    8. Part III. Environmental Considerations
    9. Part IV. Control and Management
    1. PATHOLOGY OF ANGIOSARCOMA OF THE LIVER AMONG VINYL CHLORIDE-POLYVINYL CHLORIDE WORKERS (pages 268–277)

      Louis B. Thomas and Hans Popper

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb51102.x

    2. MORPHOLOGY OF LIVER DAMAGE AMONG POLYVINYL CHLORIDE PRODUCTION WORKERS. A REPORT ON 51 CASES (pages 278–285)

      P. Gedigk, R. Müller and H. Bechtelsheimer

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb51103.x

  7. Part III. Environmental Considerations

    1. Top of page
    2. Part I. Toxicological Investigations of Vinyl Chloride-Polyvinyl Chloride A. Clinical Studies
    3. Part I. Toxicological Investigations of Vinyl Chloride-Polyvinyl Chloride B. Experimental Studies
    4. Part I. Toxicological Investigations of Vinyl Chloride-Polyvinyl Chloride C. Pathology
    5. Part I. Toxicological Investigations of Vinyl Chloride-Polyvinyl Chloride A. Experimental Studies
    6. Part I. Toxicological Investigations of Vinyl Chloride-Polyvinyl Chloride B. Epidemiological Studies
    7. Part I. Toxicological Investigations of Vinyl Chloride-Polyvinyl Chloride C. Pathology
    8. Part III. Environmental Considerations
    9. Part IV. Control and Management
    1. MEASUREMENTS OF VINYL CHLORIDE FROM AEROSOL SPRAYS (pages 286–295)

      Bruce W. Gay Jr., William A. Lonneman, Kenneth Bridbord and John B. Moran

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb51104.x

    2. ENVIRONMENTAL CONCERNS BEYOND THE WORKPLACE (pages 296–302)

      Glenn E. Schweitzer

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb51105.x

  8. Part IV. Control and Management

    1. Top of page
    2. Part I. Toxicological Investigations of Vinyl Chloride-Polyvinyl Chloride A. Clinical Studies
    3. Part I. Toxicological Investigations of Vinyl Chloride-Polyvinyl Chloride B. Experimental Studies
    4. Part I. Toxicological Investigations of Vinyl Chloride-Polyvinyl Chloride C. Pathology
    5. Part I. Toxicological Investigations of Vinyl Chloride-Polyvinyl Chloride A. Experimental Studies
    6. Part I. Toxicological Investigations of Vinyl Chloride-Polyvinyl Chloride B. Epidemiological Studies
    7. Part I. Toxicological Investigations of Vinyl Chloride-Polyvinyl Chloride C. Pathology
    8. Part III. Environmental Considerations
    9. Part IV. Control and Management
    1. DISCUSSION PAPER (pages 303–305)

      Morton Corn

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb51106.x

    2. EXPERIENCE IN INDUSTRIAL EXPOSURE CONTROL (pages 306–310)

      V. K. Rowe

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb51107.x

    3. SURVEILLANCE OF WORKERS WITH HISTORY OF EXPOSURE TO VINYL CHLORIDE (pages 311–312)

      G. Perkel, A. Mazzocchi and L. Beliczky

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb51108.x

    4. CLINICAL MANAGEMENT OF WORKERS EXPOSED TO VINYL CHLORIDE AND POLYVINYL CHLORIDE (pages 313–319)

      Clifford A. Johnson

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb51109.x

    5. DISCUSSION PAPER (pages 320–321)

      Richard Doll

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb51110.x

    6. A BIBLIOGRAPHY ON THE TOXICOLOGY OF VINYL CHLORIDE AND POLYVINYL CHLORIDE (pages 322–337)

      Harry Heimann, Ruth Lilis and Donald T. Hawkins

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb51111.x

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