Annals of the New York Academy of Sciences

Cover image for Annals of the New York Academy of Sciences

August 1975

Volume 259 Carcinofetal Proteins: Biology and Chemistry

Pages 5–452

    1. OPENING REMARKS (pages 5–6)

      Hidematsu Hirai and Elliot Alpert

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb25396.x

  1. PART I. BIOLOGY OF AL-FETOPROTEOIN

    1. Top of page
    2. PART I. BIOLOGY OF AL-FETOPROTEOIN
    3. PART II. BIOCHEMISTRY AND METABOLISM OF α-FETOPROTEIN
    4. PART III. α-FETOPROTEIN AND ONCOGENESIS
    5. PART IV. CARCINOEMBRYONIC ISOENZYMES
    6. PART V. THE BIOLOGY AND CHEMISTRY OF CARCINOEMBRYONIC ANTIGEN
    7. PART VI. CARCINOFETAL SERUM PROTEINS
    1. NORMAL BIOLOGY OF α-FETOPROTEIN (pages 7–16)

      David Gitlin

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb25397.x

    2. EVOLUTION OF α-FETOPROTEIN SERUM LEVELS THROUGHOUT LIFE IN HUMANS AND RATS, AND DURING PREGNANCY IN THE RAT (pages 17–28)

      R. Masseyeff, J. Gilli, B. Krebs, A. Calluaud and C. Bonet

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb25398.x

    3. SYNTHESIS OF α-FETOPROTEIN BY RAT ASCITES HEPATOMA CELLS (pages 29–36)

      Koichi Kanai, Yasuo Endo, Toshitsugu Oda and Yoshiyasu Kaneko

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb25399.x

    4. α-FETOPROTEIN AND ALBUMIN SYNTHESIS DURING THE CELL CYCLE (pages 37–44)

      Yutaka Tsukada and Hidematsu Hirai

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb25400.x

    5. RELATIONSHIP OF THE BIOSYNTHESIS OF α-FETOPROTEIN, ALBUMIN, HEMOPEXIN, AND HAPTOGLOBIN TO THE GROWTH STATE OF FETAL RAT HEPATOCYTE CULTURES (pages 45–58)

      S. Sell, H. L. Leffert, U. Muller-Eberhard, S. Kida and H. Skelly

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb25401.x

    6. FETAL PATHOPHYSIOLOGY OF HUMAN α-FETOPROTEIN (pages 59–73)

      Markku Seppälä

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb25402.x

    7. α-FETOPROTEIN SYNTHESIS IN CULTURED CELLS: STUDIES ON YOSHIDA SARCOMA AND ASCITES HEPATOMA IN VITRO (pages 74–79)

      Hidehiko Isaka, Sumiko Umehara and Yutaka Tsukada

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb25403.x

    8. DIFFERENT MECHANISMS OF INCREASED α-FETOPROTEIN PRODUCTION IN RATS FOLLOWING CCl4 INTOXICATION AND PARTIAL HEPATECTOMY (pages 80–84)

      Kazuhisa Taketa, Akiharu Watanabe and Kiyowo Kosaka

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb25404.x

  2. PART II. BIOCHEMISTRY AND METABOLISM OF α-FETOPROTEIN

    1. Top of page
    2. PART I. BIOLOGY OF AL-FETOPROTEOIN
    3. PART II. BIOCHEMISTRY AND METABOLISM OF α-FETOPROTEIN
    4. PART III. α-FETOPROTEIN AND ONCOGENESIS
    5. PART IV. CARCINOEMBRYONIC ISOENZYMES
    6. PART V. THE BIOLOGY AND CHEMISTRY OF CARCINOEMBRYONIC ANTIGEN
    7. PART VI. CARCINOFETAL SERUM PROTEINS
    1. EFFECT OF CHEMICAL MODIFICATION ON THE IMMUNO-GENICITY OF HOMOLOGOUS α-FETOPROTEIN (pages 85–94)

      Erkki Ruoslahti and Helena Pihko

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb25405.x

    2. MICROHETEROGENEITY OF RAT α-FETOPROTEIN (pages 95–108)

      Akiharu Watanabe, Kazuhisa Taketa and Kiyowo Kosaka

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb25406.x

    3. IMMUNOLOGICAL AND CHEMICAL CORRELATION BETWEEN α-FETOPROTEINS FROM HUMAN AND SEVERAL MAMMALIAN SPECIES (pages 109–118)

      Shinzo Nishi, Hiroyuki Watabe and Hidematsu Hirai

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb25407.x

    4. LIVER DIFFERENTIATION AND THE ESTROGEN-BINDING PROPERTIES OF α-FETOPROTEIN (pages 119–130)

      José Uriel, Claude Aussel, Danielle Bouillon, Félix Loisillier and Béatrice de Nechaud

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb25408.x

    5. HUMAN α-FETOPROTEIN IMMUNOCHEMICAL ANALYSIS OF ISOPROTEINS (pages 131–135)

      Elliot Alpert and Ruth Coston Perencevich

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb25409.x

    6. α-FETOPROTEIN LEVELS IN NORMAL MALES FROM SEVEN ETHNIC GROUPS WITH DIFFERENT HEPATOCELLULAR CARCINOMA RISKS (pages 136–155)

      P. Sizaret, A. Tuyns, N. Martel, A. Jouvenceaux, A. Levin, Y. W. Ong and J. Rive

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb25410.x

  3. PART III. α-FETOPROTEIN AND ONCOGENESIS

    1. Top of page
    2. PART I. BIOLOGY OF AL-FETOPROTEOIN
    3. PART II. BIOCHEMISTRY AND METABOLISM OF α-FETOPROTEIN
    4. PART III. α-FETOPROTEIN AND ONCOGENESIS
    5. PART IV. CARCINOEMBRYONIC ISOENZYMES
    6. PART V. THE BIOLOGY AND CHEMISTRY OF CARCINOEMBRYONIC ANTIGEN
    7. PART VI. CARCINOFETAL SERUM PROTEINS
    1. α-FETOPROTEIN AND HEPATITIS B ANTIGEN IN HEPATOCARCINOGENESIS (pages 156–167)

      Masami Sakurai and Toru Miyaji

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb25411.x

    2. α-FETOPROTEIN AND EARLY HISTOLOGICAL CHANGES OF HEPATIC TISSUE IN DAB-HEPATOCARCINOGENESIS (pages 168–180)

      Tamenori Onoé, Aiko Kaneko, Kimimaro Dempo, Katsuhiro Ogawa and Takashi Minase

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb25412.x

    3. THE α-FETOPROTEIN-PRODUCING CELLS IN THE EARLY STAGE OF THE EXPERIMENTAL LIVER CANCER (pages 217–220)

      Sanehiko Fujita, Hideo Ishizuka, Naoya Kamimura, Haruo Kaneda and Kaizo Ariga

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb25416.x

    4. α-FETOPROTEIN IN YOLK SAC TUMOR (pages 221–233)

      Yoshiaki Tsuchida, Yasuo Endo, Yoshinori Urano and Masanobu Ishida

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb25417.x

    5. CLINICAL SIGNIFICANCE OF α-FETOPROTEIN IN HEPATITIS AND LIVER CIRRHOSIS (pages 234–238)

      Y. Endo, K. Kanai, T. Oda, K. Mitamura, S. Iino and H. Suzuki

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb25418.x

    6. EPIDEMIOLOGICAL STUDIES OF α-FETOPROTEIN AND HEPATITIS B ANTIGEN IN TOMIÉ TOWN, NAGASAKI, JAPAN (pages 239–247)

      Toshihiko Koji, Tatsuo Munehisa, Kunitaro Yamaguchi, Yukio Kusumoto and Susumu Nakamura

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb25419.x

    7. AFP-PRODUCING CELLS IN HEPATITIS AND IN LIVER CIRRHOSIS (pages 253–258)

      Shi-ichi Sakamoto, Akira Yachi, Tetsuro Anzai and Takeo Wada

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb25421.x

    8. α-FETOPROTEIN AND HEPATITIS B ANTIGEN IN HEPATOMA AND HEPATITIS (pages 259–260)

      Fumihiro Ichida and Koichi Shibasaki

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb25422.x

  4. PART IV. CARCINOEMBRYONIC ISOENZYMES

    1. Top of page
    2. PART I. BIOLOGY OF AL-FETOPROTEOIN
    3. PART II. BIOCHEMISTRY AND METABOLISM OF α-FETOPROTEIN
    4. PART III. α-FETOPROTEIN AND ONCOGENESIS
    5. PART IV. CARCINOEMBRYONIC ISOENZYMES
    6. PART V. THE BIOLOGY AND CHEMISTRY OF CARCINOEMBRYONIC ANTIGEN
    7. PART VI. CARCINOFETAL SERUM PROTEINS
    1. PLACENTAL ALKALINE PHOSPHATASE: REGULATION OF EXPRESSION IN CANCER CELLS (pages 261–272)

      William H. Fishman and Robert M. Singer

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb25423.x

    2. CARCINOFETAL ALTERATIONS IN GLYCOGEN PHOSPHORYLASE ISOZYMES IN RAT HEPATOMAS (pages 273–286)

      Kiyomi Sato, Tsuyoshi Sato, Harold P. Morris and Sidney Weinhouse

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb25424.x

    3. BIOCHEMICAL AND IMMUNOLOGICAL STUDIES OF SOME CARCINOFETAL ENZYMES (pages 287–297)

      Antoinette Hatzfeld, Anne Weber and Fanny Schapira

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb25425.x

    4. CARCINOFETAL ALTERATIONS IN GLUCOSAMINE-6-PHOSPHATE SYNTHETASE (pages 298–306)

      Shigeru Tsuiki and Taeko Miyagi

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb25426.x

    5. TUMOR-SPECIFIC ALKALINE PHOSPHATASE IN HEPATOMA (pages 307–320)

      Hiroshi Suzuki, Shiro Iino, Yasuo Endo, Masao Torii, Kazumasa Miki and Toshitsugu Oda

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb25427.x

    6. DETECTION OF CARCINOPLACENTAL ALKALINE PHOSPHATASE BY THIN LAYER POLYACRYLAMIDE GEL ELECTROPHORESIS (pages 321–324)

      M. Masuzawa, T. Kamada, Y. Sakoyama, Z. Ogita and F. Ito

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb25428.x

    7. L-LEUCINE SENSITIVE ALKALINE PHOSPHATASE ISOZYME FROM CANCER TISSUE (pages 325–336)

      Toshimasa Nakayama and Motoshi Kitamura

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb25429.x

    8. A HEPATOMA-ASSOCIATED ALKALINE PHOSPHATASE, THE KASAHARA ISOZYME, COMPARED WITH ONE OF THE ISOZYMES OF FL AMNION CELLS (pages 337–346)

      Kazuya Higashino, Shunjiro Kudo, Richiko Ohtani, Yuichi Yamamura, Takeshi Honda and Jun Sakurai

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb25430.x

  5. PART V. THE BIOLOGY AND CHEMISTRY OF CARCINOEMBRYONIC ANTIGEN

    1. Top of page
    2. PART I. BIOLOGY OF AL-FETOPROTEOIN
    3. PART II. BIOCHEMISTRY AND METABOLISM OF α-FETOPROTEIN
    4. PART III. α-FETOPROTEIN AND ONCOGENESIS
    5. PART IV. CARCINOEMBRYONIC ISOENZYMES
    6. PART V. THE BIOLOGY AND CHEMISTRY OF CARCINOEMBRYONIC ANTIGEN
    7. PART VI. CARCINOFETAL SERUM PROTEINS
    1. STRUCTURAL STUDIES ON THE CARCINOEMBRYONIC ANTIGEN (pages 355–365)

      John E. Coligan, Marianne L. Egan, Ruth L. Guyer, William C. Schnute Jr. and Charles W. Todd

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb25432.x

    2. HETEROGENEITY OF CARCINOEMBRYONIC ANTIGEN : I. CONCANAVALIN A-REACTIVE AND-NONREACTIVE CEA (pages 366–376)

      Goro Kosaki and Takaki Yamamoto

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb25433.x

    3. HETEROGENEITY OF CARCINOEMBRYONIC ANTIGEN : II. MONOSACCHARIDE COMPOSITION OF CONCANAVALIN A-REACTIVE AND -NONREACTIVE CEA (pages 377–381)

      Takaki Yamamoto, Goro Kosaki, Ineo Ishizuka and Tamio Yamakawa

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb25434.x

    4. RELATIONSHIP BETWEEN CARCINOEMBRYONIC ANTIGEN AND BLOOD GROUP ANTIGENS A, B, AND LEWIS (pages 389–403)

      J.-P. Mach, K. Singh, J. Perrinjaquet, S. Carrel, C. Merenda, D. MacDonald and A. Holburn

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb25436.x

    5. COLON CARCINOMA ANTIGENS IN THE RAT (pages 404–411)

      Hans Olov Sjögren and Glenn Steele Jr.

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb25437.x

    6. IMMUNOPATHOLOGICAL STUDIES ON CEA AND CEAASSOCIATED ANTIGENS WITH REEVALUATION OF THE CANCER SPECIFICITIES OF CEA (pages 412–416)

      Takesada Mori, Hiroshi Wakumoto, Takashi Shimano, Par-Khen Lee and Hiromu Higashi

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb25438.x

  6. PART VI. CARCINOFETAL SERUM PROTEINS

    1. Top of page
    2. PART I. BIOLOGY OF AL-FETOPROTEOIN
    3. PART II. BIOCHEMISTRY AND METABOLISM OF α-FETOPROTEIN
    4. PART III. α-FETOPROTEIN AND ONCOGENESIS
    5. PART IV. CARCINOEMBRYONIC ISOENZYMES
    6. PART V. THE BIOLOGY AND CHEMISTRY OF CARCINOEMBRYONIC ANTIGEN
    7. PART VI. CARCINOFETAL SERUM PROTEINS
    1. CARCINOFETAL HUMAN ISOFERRITINS (pages 427–434)

      James W. Drysdale and Elliot Alpert

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb25440.x

    2. CLINICAL SIGNIFICANCE OF α2H-GLOBULIN (pages 435–445)

      Akira Yachi, Yoshikazu Akahonai, Akira Takahashi and Takeo Wada

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb25441.x

    3. ANTIPLACENTAL FERRITIN ANTISERUM FOR CANCER DIAGNOSIS (pages 446–449)

      Wataru Mori, Hideo Asakawa and Tomoya Taguchi

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb25442.x

    4. RADIOIMMUNOASSAY OF SERUM FERRITIN IN PATIENTS WITH MALIGNANCY (pages 450–452)

      Yoshiro Niitsu, Yutaka Kohgo, Minoru Yokota and Ichiro Urushizaki

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1975.tb25443.x

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