Annals of the New York Academy of Sciences

Cover image for Annals of the New York Academy of Sciences

September 1978

Volume 311 Recent Developments in Chemotherapy of Narcotic Addiction

Pages 1–313

  1. INTRODUCTION

    1. Top of page
    2. INTRODUCTION
    3. Part I. Epidemiology and Characteristics of Drug Abuse
    4. Part II. Opiate Receptors and Endorphins
    5. Part III. Tolerance and Physical Dependence on Drugs
    6. Part IV. Medical Aspects of Methadone Maintenance
    7. Part V. Rational Approach to Detoxification from Methadone Maintenance
    8. Part VI. LAAM and Narcotic Antagonists
    9. Part VII. Evaluation of Treatment Effectiveness
    10. Part VIII. Current Trends in Narcotic Addiction Treatment
    1. INTRODUCTION (pages 1–3)

      Benjamin Kissin, Joyce H. Lowinson and Robert B. Millman

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb16757.x

  2. Part I. Epidemiology and Characteristics of Drug Abuse

    1. Top of page
    2. INTRODUCTION
    3. Part I. Epidemiology and Characteristics of Drug Abuse
    4. Part II. Opiate Receptors and Endorphins
    5. Part III. Tolerance and Physical Dependence on Drugs
    6. Part IV. Medical Aspects of Methadone Maintenance
    7. Part V. Rational Approach to Detoxification from Methadone Maintenance
    8. Part VI. LAAM and Narcotic Antagonists
    9. Part VII. Evaluation of Treatment Effectiveness
    10. Part VIII. Current Trends in Narcotic Addiction Treatment
    1. NARCOTISM: DIMENSIONS OF THE PROBLEM (pages 4–9)

      Sidney Cohen

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb16758.x

    2. PATTERNS OF HEROIN USE (pages 10–24)

      Norman E. Zinberg, Wayne M. Harding, Shirley M. Stelmack and Robert A. Marblestone

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb16759.x

    3. BIOSTATISTICAL PERSPECTIVES IN THE EPIDEMIOLOGY OF NARCOTIC ABUSE (pages 25–33)

      H. Smith, J.D. Goldberg and D.C. Korts

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb16760.x

  3. Part II. Opiate Receptors and Endorphins

    1. Top of page
    2. INTRODUCTION
    3. Part I. Epidemiology and Characteristics of Drug Abuse
    4. Part II. Opiate Receptors and Endorphins
    5. Part III. Tolerance and Physical Dependence on Drugs
    6. Part IV. Medical Aspects of Methadone Maintenance
    7. Part V. Rational Approach to Detoxification from Methadone Maintenance
    8. Part VI. LAAM and Narcotic Antagonists
    9. Part VII. Evaluation of Treatment Effectiveness
    10. Part VIII. Current Trends in Narcotic Addiction Treatment
    1. OPIATE RECEPTORS: SOME ANATOMICAL AND PHYSIOLOGICAL ASPECTS (pages 35–48)

      Michael J. Kuhar

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb16761.x

    2. ENDORPHINS: PHYSIOLOGY AND CLINICAL IMPLICATIONS (pages 49–58)

      Avram Goldstein

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb16762.x

  4. Part III. Tolerance and Physical Dependence on Drugs

    1. Top of page
    2. INTRODUCTION
    3. Part I. Epidemiology and Characteristics of Drug Abuse
    4. Part II. Opiate Receptors and Endorphins
    5. Part III. Tolerance and Physical Dependence on Drugs
    6. Part IV. Medical Aspects of Methadone Maintenance
    7. Part V. Rational Approach to Detoxification from Methadone Maintenance
    8. Part VI. LAAM and Narcotic Antagonists
    9. Part VII. Evaluation of Treatment Effectiveness
    10. Part VIII. Current Trends in Narcotic Addiction Treatment
    1. INTRODUCTORY REMARKS (page 59)

      Charles W. Gorodetzky

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb16763.x

    2. BASIC MECHANISMS IN NARCOTIC TOLEARANCE AND PHYSICAL DEPENDENCE (pages 61–68)

      E. Leong Way

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb16764.x

    3. BASIC MECHANISMS UNDERLYING PHYSICAL DEPENDENCE UPON ALCOHOL (pages 69–79)

      Jack H. Mendelson and Nancy K. Mello

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb16765.x

  5. Part IV. Medical Aspects of Methadone Maintenance

    1. Top of page
    2. INTRODUCTION
    3. Part I. Epidemiology and Characteristics of Drug Abuse
    4. Part II. Opiate Receptors and Endorphins
    5. Part III. Tolerance and Physical Dependence on Drugs
    6. Part IV. Medical Aspects of Methadone Maintenance
    7. Part V. Rational Approach to Detoxification from Methadone Maintenance
    8. Part VI. LAAM and Narcotic Antagonists
    9. Part VII. Evaluation of Treatment Effectiveness
    10. Part VIII. Current Trends in Narcotic Addiction Treatment
    1. OPENING REMARKS (page 80)

      Edward C. Senay

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb16766.x

    2. USE OF PSYCHOTROPIC DRUGS IN TREATMENT OF METHADONE MAINTAINED NARCOTIC ADDICTS (pages 81–98)

      Herbert D. Kleber and Mark S. Gold

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb16767.x

    3. ALCOHOLISM AND POLYDRUG ABUSE IN PERSONS OF METHADONE MAINTENANCE (pages 99–109)

      Barry Stimmel, Murry Cohen and Ray Hanbury

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb16768.x

    4. MEDICAL COMPLICATIONS IN METHADONE PATIENTS (pages 110–134)

      Mary Jeanne Kreek

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb16769.x

    5. MANAGEMENT OF PREGNANT DRUG-DEPENDENT WOMEN (pages 135–146)

      Loretta P. Finnegan

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb16770.x

    6. GENERAL OVERVIEW OF NARCOTIC ADDICTION TREATMENT PROGRAMS (pages 147–152)

      Peter G. Bourne

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb16771.x

  6. Part V. Rational Approach to Detoxification from Methadone Maintenance

    1. Top of page
    2. INTRODUCTION
    3. Part I. Epidemiology and Characteristics of Drug Abuse
    4. Part II. Opiate Receptors and Endorphins
    5. Part III. Tolerance and Physical Dependence on Drugs
    6. Part IV. Medical Aspects of Methadone Maintenance
    7. Part V. Rational Approach to Detoxification from Methadone Maintenance
    8. Part VI. LAAM and Narcotic Antagonists
    9. Part VII. Evaluation of Treatment Effectiveness
    10. Part VIII. Current Trends in Narcotic Addiction Treatment
    1. THERAPEUTIC DETOXIFICATION OF ADOLESCENT HEROIN ADDICTS (pages 153–164)

      Robert B. Millman, Elizabeth T. Khuri and Marie E. Nyswander

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb16772.x

    2. METHADONE MAINTENANCE: LONG-TERM FOLLOW-UP OF DETOXIFIED PATIENTS (pages 165–172)

      Paul Cushman Jr.

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb16773.x

    3. DETOXIFICATION FROM METHADONE MAINTENANCE: RISK FACTORS ASSOCIATED WITH RELAPSE TO NARCOTIC USE (pages 173–180)

      Barry Stimmel, Judith Goldberg, Murry Cohen and Edith Rotkopf

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb16774.x

    4. LONG-TERM OUTCOME OF PATIENTS TREATED WITH METHADONE MAINTENANCE (pages 181–196)

      Vincent P. Dole and Herman Joseph

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb16775.x

  7. Part VI. LAAM and Narcotic Antagonists

    1. Top of page
    2. INTRODUCTION
    3. Part I. Epidemiology and Characteristics of Drug Abuse
    4. Part II. Opiate Receptors and Endorphins
    5. Part III. Tolerance and Physical Dependence on Drugs
    6. Part IV. Medical Aspects of Methadone Maintenance
    7. Part V. Rational Approach to Detoxification from Methadone Maintenance
    8. Part VI. LAAM and Narcotic Antagonists
    9. Part VII. Evaluation of Treatment Effectiveness
    10. Part VIII. Current Trends in Narcotic Addiction Treatment
    1. INTRODUCTORY REMARKS (pages 197–198)

      Donald R. Jasinski

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb16776.x

    2. PHARMACOLOGY OF ℓ-α-ACETYLMETHADOL (LAAM) IN SUBHUMAN PRIMATES (pages 199–213)

      S.J. Mulé and A.L. Misra

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb16777.x

    3. CLINICAL USE OF LAAM (pages 214–231)

      Jack D. Blaine, Pierre Renault, Gail L. Levine and John A. Whysner

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb16778.x

    4. CLINICAL PHARMACOLOGY OF NARCOTIC ANTAGONISTS (pages 232–240)

      Charles P. O'Brien, Robert Greenstein, Joseph Ternes and George E. Woody

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb16779.x

    5. CLINICAL OUTCOME WITH NALTREXONE (pages 241–247)

      Richard B. Resnick and Arnold M. Washton

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb16780.x

  8. Part VII. Evaluation of Treatment Effectiveness

    1. Top of page
    2. INTRODUCTION
    3. Part I. Epidemiology and Characteristics of Drug Abuse
    4. Part II. Opiate Receptors and Endorphins
    5. Part III. Tolerance and Physical Dependence on Drugs
    6. Part IV. Medical Aspects of Methadone Maintenance
    7. Part V. Rational Approach to Detoxification from Methadone Maintenance
    8. Part VI. LAAM and Narcotic Antagonists
    9. Part VII. Evaluation of Treatment Effectiveness
    10. Part VIII. Current Trends in Narcotic Addiction Treatment
    1. THE NEW YORK STATE EXPERIENCE (pages 248–252)

      Daniel Klepak

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb16781.x

    2. EVALUATION OF TREATMENT EFFECTIVENESS: VETERANS ADMINISTRATION EXPERIENCE (pages 253–264)

      Stewart L. Baker Jr. and Theodore W. Lorei

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb16782.x

    3. DEFENSIVE RESEARCH—THE TREATMENT OUTCOME PROSPECTIVE STUDY (TOPS) (page 265)

      Harold M. Ginzburg

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb16783.x

    4. EVALUATION OF PRESENT TREATMENT MODALITIES: RESEARCH WITH DARP ADMISSIONS, 1969–1973 (pages 270–281)

      S.B. Sells, R.G. Demaree, D.D. Simpson and George W. Joe

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb16784.x

  9. Part VIII. Current Trends in Narcotic Addiction Treatment

    1. Top of page
    2. INTRODUCTION
    3. Part I. Epidemiology and Characteristics of Drug Abuse
    4. Part II. Opiate Receptors and Endorphins
    5. Part III. Tolerance and Physical Dependence on Drugs
    6. Part IV. Medical Aspects of Methadone Maintenance
    7. Part V. Rational Approach to Detoxification from Methadone Maintenance
    8. Part VI. LAAM and Narcotic Antagonists
    9. Part VII. Evaluation of Treatment Effectiveness
    10. Part VIII. Current Trends in Narcotic Addiction Treatment
    1. PATIENT ACCEPTABILITY AND CLINICAL APPLICABILITY OF ALTERNATIVE TREATMENT METHODS (pages 282–295)

      Benjamin Kissin, Dan Arnon and Fran Luckom-Nurnberg

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb16785.x

    2. TOWARD A COHERENT SYSTEM OF NARCOTIC ADDICTION TREATMENT (pages 296–301)

      Lee I. Dogoloff

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb16786.x

    3. STATUS REPORT ON NATIONAL DRUG ABUSE TREATMENT CAPACITY (pages 302–313)

      Robert L. DuPont Jr.

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb16787.x

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