Annals of the New York Academy of Sciences

Cover image for Annals of the New York Academy of Sciences

November 1978

Volume 315 Brain Death: Interrelated Medical and Social Issues

Pages 1–441

    1. PREFACE (pages 1–5)

      Julius Korein

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb50324.x

    2. TERMINOLOGY, DEFINITIONS, AND USAGE (pages 6–10)

      Julius Korein

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb50325.x

  1. Part I. General Introduction

    1. Top of page
    2. Part I. General Introduction
    3. Part II. Medical Criteria OF Brain Death: Clinical Criteria
    4. Part II. Medical Criteria OF Brain Death: Brain Metabolism
    5. Part II. Medical Criteria OF Brain Death: The Electroencephalogram and Brain Death
    6. Part II. Medical Criteria OF Brain Death: Intracranial Circulation and Anoxia in Brain Death and“Apallic” States
    7. Part III. Other Comatose States
    8. Part IV. Ancillary Studies in Diagonis of Brain Death and Pathologic Findings Ancillary Studies
    9. Part IV. Ancillary Studies in Diagonis of Brain Death and Pathologic Findings Pathology
    10. Part V. Quality of Survival in Patients in Chronic Comas
    11. Part VI. Ethical, Social, Philosophical, and Religious Factors
    12. Part VII. Legislative Problems OF Brain Death, Irreversible States, AND THE Rights OF THE Individual
    13. Part VII. Legislative Problems OF Brain Death, irreversible States, AND THE Rights OF THE Individual
    14. Part VIII. Problems Related TO THE Intensive Care Unit AND Organ Transplantation
    1. DEATH: HISTORICAL EVOLUTION AND IMPLICATION OF THE CONCEPT (pages 11–18)

      Benjamin Boshes

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb50326.x

    2. THE PROBLEM OF BRAIN DEATH: DEVELOPMENT AND HISTORY (pages 19–38)

      Julius Korein

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb50327.x

    3. SOME PRELIMINARY REMARKS ON BRAIN DEATH (pages 39–44)

      Richard Roelofs

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb50328.x

    4. THE DEVELOPMENT OF LAW ON HUMAN DEATH (pages 45–61)

      Alexander Morgan Capron

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb50329.x

  2. Part II. Medical Criteria OF Brain Death: Clinical Criteria

    1. Top of page
    2. Part I. General Introduction
    3. Part II. Medical Criteria OF Brain Death: Clinical Criteria
    4. Part II. Medical Criteria OF Brain Death: Brain Metabolism
    5. Part II. Medical Criteria OF Brain Death: The Electroencephalogram and Brain Death
    6. Part II. Medical Criteria OF Brain Death: Intracranial Circulation and Anoxia in Brain Death and“Apallic” States
    7. Part III. Other Comatose States
    8. Part IV. Ancillary Studies in Diagonis of Brain Death and Pathologic Findings Ancillary Studies
    9. Part IV. Ancillary Studies in Diagonis of Brain Death and Pathologic Findings Pathology
    10. Part V. Quality of Survival in Patients in Chronic Comas
    11. Part VI. Ethical, Social, Philosophical, and Religious Factors
    12. Part VII. Legislative Problems OF Brain Death, Irreversible States, AND THE Rights OF THE Individual
    13. Part VII. Legislative Problems OF Brain Death, irreversible States, AND THE Rights OF THE Individual
    14. Part VIII. Problems Related TO THE Intensive Care Unit AND Organ Transplantation
    1. REVIEW OF CLINICAL CRITERIA OF BRAIN DEATH (pages 62–69)

      Gaetano F. Molinari

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb50330.x

    2. CLINICAL CRITERIA OF BRAIN DEATH (pages 70–96)

      Norman Allen, James Burkholder and John Comiscioni

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb50331.x

  3. Part II. Medical Criteria OF Brain Death: Brain Metabolism

    1. Top of page
    2. Part I. General Introduction
    3. Part II. Medical Criteria OF Brain Death: Clinical Criteria
    4. Part II. Medical Criteria OF Brain Death: Brain Metabolism
    5. Part II. Medical Criteria OF Brain Death: The Electroencephalogram and Brain Death
    6. Part II. Medical Criteria OF Brain Death: Intracranial Circulation and Anoxia in Brain Death and“Apallic” States
    7. Part III. Other Comatose States
    8. Part IV. Ancillary Studies in Diagonis of Brain Death and Pathologic Findings Ancillary Studies
    9. Part IV. Ancillary Studies in Diagonis of Brain Death and Pathologic Findings Pathology
    10. Part V. Quality of Survival in Patients in Chronic Comas
    11. Part VI. Ethical, Social, Philosophical, and Religious Factors
    12. Part VII. Legislative Problems OF Brain Death, Irreversible States, AND THE Rights OF THE Individual
    13. Part VII. Legislative Problems OF Brain Death, irreversible States, AND THE Rights OF THE Individual
    14. Part VIII. Problems Related TO THE Intensive Care Unit AND Organ Transplantation
    1. BRAIN ENERGETICS AND CEREBRAL DEATH (pages 97–104)

      Jack M. Fein

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb50332.x

  4. Part II. Medical Criteria OF Brain Death: The Electroencephalogram and Brain Death

    1. Top of page
    2. Part I. General Introduction
    3. Part II. Medical Criteria OF Brain Death: Clinical Criteria
    4. Part II. Medical Criteria OF Brain Death: Brain Metabolism
    5. Part II. Medical Criteria OF Brain Death: The Electroencephalogram and Brain Death
    6. Part II. Medical Criteria OF Brain Death: Intracranial Circulation and Anoxia in Brain Death and“Apallic” States
    7. Part III. Other Comatose States
    8. Part IV. Ancillary Studies in Diagonis of Brain Death and Pathologic Findings Ancillary Studies
    9. Part IV. Ancillary Studies in Diagonis of Brain Death and Pathologic Findings Pathology
    10. Part V. Quality of Survival in Patients in Chronic Comas
    11. Part VI. Ethical, Social, Philosophical, and Religious Factors
    12. Part VII. Legislative Problems OF Brain Death, Irreversible States, AND THE Rights OF THE Individual
    13. Part VII. Legislative Problems OF Brain Death, irreversible States, AND THE Rights OF THE Individual
    14. Part VIII. Problems Related TO THE Intensive Care Unit AND Organ Transplantation
    1. THE EEG IN DETERMINATION OF BRAIN DEATH (pages 110–120)

      Donald R. Bennett

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb50334.x

    2. LIMITATIONS OF THE EEG IN COMA AND BRAIN DEATH (pages 121–136)

      John R. Hughes

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb50335.x

  5. Part II. Medical Criteria OF Brain Death: Intracranial Circulation and Anoxia in Brain Death and“Apallic” States

    1. Top of page
    2. Part I. General Introduction
    3. Part II. Medical Criteria OF Brain Death: Clinical Criteria
    4. Part II. Medical Criteria OF Brain Death: Brain Metabolism
    5. Part II. Medical Criteria OF Brain Death: The Electroencephalogram and Brain Death
    6. Part II. Medical Criteria OF Brain Death: Intracranial Circulation and Anoxia in Brain Death and“Apallic” States
    7. Part III. Other Comatose States
    8. Part IV. Ancillary Studies in Diagonis of Brain Death and Pathologic Findings Ancillary Studies
    9. Part IV. Ancillary Studies in Diagonis of Brain Death and Pathologic Findings Pathology
    10. Part V. Quality of Survival in Patients in Chronic Comas
    11. Part VI. Ethical, Social, Philosophical, and Religious Factors
    12. Part VII. Legislative Problems OF Brain Death, Irreversible States, AND THE Rights OF THE Individual
    13. Part VII. Legislative Problems OF Brain Death, irreversible States, AND THE Rights OF THE Individual
    14. Part VIII. Problems Related TO THE Intensive Care Unit AND Organ Transplantation
    1. EVALUATION OF THE CRITICAL DEFICIT OF CEREBRAL CIRCULATION USING RADIOACTIVE TRACERS (BOLUS TECHNIQUE) (pages 143–167)

      Philip Braunstein, Julius Korein, Irvin I. Kricheff and Abraham Lieberman

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb50337.x

    2. ANGIOGRAPHIC FINDINGS IN BRAIN DEATH (pages 168–183)

      I. I. Kricheff, R. S. Pinto, A. E. George, P. Braunstein and and J. Korein

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb50338.x

    3. SURVIVAL AFTER SEVERE CEREBRAL ANOXIA WITH DESTRUCTION OF THE CEREBRAL CORTEX: THE APALLIC SYNDROME (pages 184–214)

      David H. Ingvar, Arne Brun, Lars Johansson and and Sven Mårten Samuelsson

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb50339.x

  6. Part III. Other Comatose States

    1. Top of page
    2. Part I. General Introduction
    3. Part II. Medical Criteria OF Brain Death: Clinical Criteria
    4. Part II. Medical Criteria OF Brain Death: Brain Metabolism
    5. Part II. Medical Criteria OF Brain Death: The Electroencephalogram and Brain Death
    6. Part II. Medical Criteria OF Brain Death: Intracranial Circulation and Anoxia in Brain Death and“Apallic” States
    7. Part III. Other Comatose States
    8. Part IV. Ancillary Studies in Diagonis of Brain Death and Pathologic Findings Ancillary Studies
    9. Part IV. Ancillary Studies in Diagonis of Brain Death and Pathologic Findings Pathology
    10. Part V. Quality of Survival in Patients in Chronic Comas
    11. Part VI. Ethical, Social, Philosophical, and Religious Factors
    12. Part VII. Legislative Problems OF Brain Death, Irreversible States, AND THE Rights OF THE Individual
    13. Part VII. Legislative Problems OF Brain Death, irreversible States, AND THE Rights OF THE Individual
    14. Part VIII. Problems Related TO THE Intensive Care Unit AND Organ Transplantation
  7. Part IV. Ancillary Studies in Diagonis of Brain Death and Pathologic Findings Ancillary Studies

    1. Top of page
    2. Part I. General Introduction
    3. Part II. Medical Criteria OF Brain Death: Clinical Criteria
    4. Part II. Medical Criteria OF Brain Death: Brain Metabolism
    5. Part II. Medical Criteria OF Brain Death: The Electroencephalogram and Brain Death
    6. Part II. Medical Criteria OF Brain Death: Intracranial Circulation and Anoxia in Brain Death and“Apallic” States
    7. Part III. Other Comatose States
    8. Part IV. Ancillary Studies in Diagonis of Brain Death and Pathologic Findings Ancillary Studies
    9. Part IV. Ancillary Studies in Diagonis of Brain Death and Pathologic Findings Pathology
    10. Part V. Quality of Survival in Patients in Chronic Comas
    11. Part VI. Ethical, Social, Philosophical, and Religious Factors
    12. Part VII. Legislative Problems OF Brain Death, Irreversible States, AND THE Rights OF THE Individual
    13. Part VII. Legislative Problems OF Brain Death, irreversible States, AND THE Rights OF THE Individual
    14. Part VIII. Problems Related TO THE Intensive Care Unit AND Organ Transplantation
    1. ANCILLARY STUDIES IN THE DIAGNOSIS OF BRAIN DEATH (pages 228–240)

      A. Earl Walker

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb50341.x

    2. DISCONNECTING TESTS AND OXYGEN UPTAKE IN THE DIAGNOSIS OF TOTAL BRAIN DEATH (pages 241–251)

      A. Milhaud, M. Riboulot and and H. Gayet

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb50342.x

    3. CARDIAC AND METABOLIC ALTERATIONS IN BRAIN DEATH: DISCUSSION PAPER (pages 252–264)

      G. E. Ouaknine

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb50343.x

  8. Part IV. Ancillary Studies in Diagonis of Brain Death and Pathologic Findings Pathology

    1. Top of page
    2. Part I. General Introduction
    3. Part II. Medical Criteria OF Brain Death: Clinical Criteria
    4. Part II. Medical Criteria OF Brain Death: Brain Metabolism
    5. Part II. Medical Criteria OF Brain Death: The Electroencephalogram and Brain Death
    6. Part II. Medical Criteria OF Brain Death: Intracranial Circulation and Anoxia in Brain Death and“Apallic” States
    7. Part III. Other Comatose States
    8. Part IV. Ancillary Studies in Diagonis of Brain Death and Pathologic Findings Ancillary Studies
    9. Part IV. Ancillary Studies in Diagonis of Brain Death and Pathologic Findings Pathology
    10. Part V. Quality of Survival in Patients in Chronic Comas
    11. Part VI. Ethical, Social, Philosophical, and Religious Factors
    12. Part VII. Legislative Problems OF Brain Death, Irreversible States, AND THE Rights OF THE Individual
    13. Part VII. Legislative Problems OF Brain Death, irreversible States, AND THE Rights OF THE Individual
    14. Part VIII. Problems Related TO THE Intensive Care Unit AND Organ Transplantation
    1. MORPHOLOGY OF DEFECTIVELY PERFUSED BRAINS IN PATIENTS WITH PERSISTENT EXTRACRANIAL CIRCULATION (pages 265–271)

      John Pearson, J. Korein and P. Braunstein

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb50344.x

    2. PATHOLOGY OF BRAIN DEATH (pages 272–280)

      A. Earl Walker

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb50345.x

  9. Part V. Quality of Survival in Patients in Chronic Comas

    1. Top of page
    2. Part I. General Introduction
    3. Part II. Medical Criteria OF Brain Death: Clinical Criteria
    4. Part II. Medical Criteria OF Brain Death: Brain Metabolism
    5. Part II. Medical Criteria OF Brain Death: The Electroencephalogram and Brain Death
    6. Part II. Medical Criteria OF Brain Death: Intracranial Circulation and Anoxia in Brain Death and“Apallic” States
    7. Part III. Other Comatose States
    8. Part IV. Ancillary Studies in Diagonis of Brain Death and Pathologic Findings Ancillary Studies
    9. Part IV. Ancillary Studies in Diagonis of Brain Death and Pathologic Findings Pathology
    10. Part V. Quality of Survival in Patients in Chronic Comas
    11. Part VI. Ethical, Social, Philosophical, and Religious Factors
    12. Part VII. Legislative Problems OF Brain Death, Irreversible States, AND THE Rights OF THE Individual
    13. Part VII. Legislative Problems OF Brain Death, irreversible States, AND THE Rights OF THE Individual
    14. Part VIII. Problems Related TO THE Intensive Care Unit AND Organ Transplantation
    1. TRANSITORY ISCHEMIA/ANOXIA IN YOUNG CHILDREN AND THE PREDICTION OF QUALITY OF SURVIVAL (pages 281–292)

      G. Pampiglione, Jane Chaloner, Ann Harden and and Judith O'Brien

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb50346.x

    2. THE VEGETATIVE STATE AND ITS PROGNOSIS FOLLOWING NONTRAUMATIC COMA (pages 293–306)

      D. E. Levy, R. P. Knill-Jones and F. Plum

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb50347.x

  10. Part VI. Ethical, Social, Philosophical, and Religious Factors

    1. Top of page
    2. Part I. General Introduction
    3. Part II. Medical Criteria OF Brain Death: Clinical Criteria
    4. Part II. Medical Criteria OF Brain Death: Brain Metabolism
    5. Part II. Medical Criteria OF Brain Death: The Electroencephalogram and Brain Death
    6. Part II. Medical Criteria OF Brain Death: Intracranial Circulation and Anoxia in Brain Death and“Apallic” States
    7. Part III. Other Comatose States
    8. Part IV. Ancillary Studies in Diagonis of Brain Death and Pathologic Findings Ancillary Studies
    9. Part IV. Ancillary Studies in Diagonis of Brain Death and Pathologic Findings Pathology
    10. Part V. Quality of Survival in Patients in Chronic Comas
    11. Part VI. Ethical, Social, Philosophical, and Religious Factors
    12. Part VII. Legislative Problems OF Brain Death, Irreversible States, AND THE Rights OF THE Individual
    13. Part VII. Legislative Problems OF Brain Death, irreversible States, AND THE Rights OF THE Individual
    14. Part VIII. Problems Related TO THE Intensive Care Unit AND Organ Transplantation
    1. THE DEFINITION OF DEATH: ETHICAL, PHILOSOPHICAL, AND POLICY CONFUSION (pages 307–321)

      Robert M. Veatch

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb50348.x

    2. THE SOCIAL EFFECTS OF CHANGING ATTITUDES TOWARDS DEATH (pages 322–328)

      James P. Carse

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb50349.x

    3. RELIGIOUS CONCEPTS OF BRAIN DEATH AND ASSOCIATED PROBLEMS (pages 329–338)

      Stanley Hauerwas

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb50350.x

  11. Part VII. Legislative Problems OF Brain Death, Irreversible States, AND THE Rights OF THE Individual

    1. Top of page
    2. Part I. General Introduction
    3. Part II. Medical Criteria OF Brain Death: Clinical Criteria
    4. Part II. Medical Criteria OF Brain Death: Brain Metabolism
    5. Part II. Medical Criteria OF Brain Death: The Electroencephalogram and Brain Death
    6. Part II. Medical Criteria OF Brain Death: Intracranial Circulation and Anoxia in Brain Death and“Apallic” States
    7. Part III. Other Comatose States
    8. Part IV. Ancillary Studies in Diagonis of Brain Death and Pathologic Findings Ancillary Studies
    9. Part IV. Ancillary Studies in Diagonis of Brain Death and Pathologic Findings Pathology
    10. Part V. Quality of Survival in Patients in Chronic Comas
    11. Part VI. Ethical, Social, Philosophical, and Religious Factors
    12. Part VII. Legislative Problems OF Brain Death, Irreversible States, AND THE Rights OF THE Individual
    13. Part VII. Legislative Problems OF Brain Death, irreversible States, AND THE Rights OF THE Individual
    14. Part VIII. Problems Related TO THE Intensive Care Unit AND Organ Transplantation
    1. COGNITIVE DEATH: DIFFERENTIAL PROBLEMS AND LEGAL OVERTONES (pages 339–348)

      H. Richard Beresford

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb50351.x

    2. LEGAL DEFINITION OF DEATH (pages 349–362)

      Alexander Morgan Capron

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb50352.x

  12. Part VII. Legislative Problems OF Brain Death, irreversible States, AND THE Rights OF THE Individual

    1. Top of page
    2. Part I. General Introduction
    3. Part II. Medical Criteria OF Brain Death: Clinical Criteria
    4. Part II. Medical Criteria OF Brain Death: Brain Metabolism
    5. Part II. Medical Criteria OF Brain Death: The Electroencephalogram and Brain Death
    6. Part II. Medical Criteria OF Brain Death: Intracranial Circulation and Anoxia in Brain Death and“Apallic” States
    7. Part III. Other Comatose States
    8. Part IV. Ancillary Studies in Diagonis of Brain Death and Pathologic Findings Ancillary Studies
    9. Part IV. Ancillary Studies in Diagonis of Brain Death and Pathologic Findings Pathology
    10. Part V. Quality of Survival in Patients in Chronic Comas
    11. Part VI. Ethical, Social, Philosophical, and Religious Factors
    12. Part VII. Legislative Problems OF Brain Death, Irreversible States, AND THE Rights OF THE Individual
    13. Part VII. Legislative Problems OF Brain Death, irreversible States, AND THE Rights OF THE Individual
    14. Part VIII. Problems Related TO THE Intensive Care Unit AND Organ Transplantation
    1. EUTHANASIA AND BRAIN DEATH: ETHICAL AND LEGAL CONSIDERATIONS (pages 363–375)

      Dennis J. Horan

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb50353.x

    2. THE NATURAL DEATH ACT: A WELL-BABY CHECK-UP ON ITS FIRST BIRTHDAY (pages 376–393)

      Barry Keene

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb50354.x

  13. Part VIII. Problems Related TO THE Intensive Care Unit AND Organ Transplantation

    1. Top of page
    2. Part I. General Introduction
    3. Part II. Medical Criteria OF Brain Death: Clinical Criteria
    4. Part II. Medical Criteria OF Brain Death: Brain Metabolism
    5. Part II. Medical Criteria OF Brain Death: The Electroencephalogram and Brain Death
    6. Part II. Medical Criteria OF Brain Death: Intracranial Circulation and Anoxia in Brain Death and“Apallic” States
    7. Part III. Other Comatose States
    8. Part IV. Ancillary Studies in Diagonis of Brain Death and Pathologic Findings Ancillary Studies
    9. Part IV. Ancillary Studies in Diagonis of Brain Death and Pathologic Findings Pathology
    10. Part V. Quality of Survival in Patients in Chronic Comas
    11. Part VI. Ethical, Social, Philosophical, and Religious Factors
    12. Part VII. Legislative Problems OF Brain Death, Irreversible States, AND THE Rights OF THE Individual
    13. Part VII. Legislative Problems OF Brain Death, irreversible States, AND THE Rights OF THE Individual
    14. Part VIII. Problems Related TO THE Intensive Care Unit AND Organ Transplantation
    1. CLINICAL PROBLEMS OF BRAIN DEATH AND COMA IN INTENSIVE CARE UNITS (pages 398–416)

      Cary Suter and John Brush

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb50356.x

    2. BRAIN DEATH AND ORGAN TRANSPLANTATION , † (pages 417–441)

      Frank J. Veith

      Article first published online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1978.tb50357.x

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