Annals of the New York Academy of Sciences

Cover image for Annals of the New York Academy of Sciences

July 1986

Volume 475 Autoimmunity: Experimental and Clinical Aspects

Pages 1–423

  1. PART I. GENETICS OF AUTOIMMUNITY

    1. Top of page
    2. PART I. GENETICS OF AUTOIMMUNITY
    3. PART II. IDIOTYPE NETWORK
    4. PART III. PROPERTIES OF AUTOANTIBODIES
    5. PART IV. ORIGINS OF AUTOANTIBODIES
    6. PART V. NEW FORMS OF THERAPY
    7. POSTER PAPERS
    8. Experimental Allergic Orchitis in Mice
    1. Molecular Genetics and T Cells in Autoimmunity (pages 12–23)

      PETER STASTNY, LINDA K. MYERS, GABRIEL NUÑEZ, MARIE L. MARIE L, J. DONALD CAPRA and EDWARD J. BALL

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1986.tb20852.x

    2. Gene Conversion A Mechanism to Explain HLA-D Region and Disease Association (pages 24–31)

      C. GARRISON FATHMAN, JORG GORONZY and CORNELIA WEYAND

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1986.tb20853.x

    3. Genetics of the Complement System (pages 32–46)

      CHESTER A. ALPER

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1986.tb20854.x

    4. Origins of Pathogenic Anti-DNA Idiotypes in the NZB X SWR Model of Lupus Nephritis (pages 47–58)

      SYAMAL K. DATTA and JERRIE GAVALCHIN

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1986.tb20855.x

    5. Auto-Epitopes and Autoimmune Diseases (pages 59–65)

      IAN R. MACKAY, IAN H. FRAZER, L. JANE MCNEILAGE and SENGA WHITTINGHAM

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1986.tb20856.x

  2. PART II. IDIOTYPE NETWORK

    1. Top of page
    2. PART I. GENETICS OF AUTOIMMUNITY
    3. PART II. IDIOTYPE NETWORK
    4. PART III. PROPERTIES OF AUTOANTIBODIES
    5. PART IV. ORIGINS OF AUTOANTIBODIES
    6. PART V. NEW FORMS OF THERAPY
    7. POSTER PAPERS
    8. Experimental Allergic Orchitis in Mice
    1. Anti-Idiotypic Immunity in Autoimmunity (pages 66–80)

      PIERLUIGI E. BIGAZZI

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1986.tb20857.x

    2. Idiotypes and Anti-Idiotypes in Experimental Autoimmune Myasthenia Gravis (pages 81–93)

      MIRIAM C. SOUROUJON and SARA FUCHS

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1986.tb20858.x

    3. T and B Cell Connections in Experimentally Induced Autoimmunity (pages 94–105)

      D. K. MALE, G. PRYCE, A. COOKE, P. HUTCHINGS, S. MARSHALL and I. M. ROITT

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1986.tb20859.x

    4. Rheumatoid Factors Immunochemical, Molecular, and Regulatory Properties (pages 106–113)

      MARC MONESTIER, BLANCHE BELLON, AUDREY J. MANHEIMER and CONSTANTIN A. BONA

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1986.tb20860.x

    5. A Novel Chimeric Antibody with Circular Network Characteristics: Autobody (pages 114–122)

      CHANG-YUIL KANG and HEINZ KOHLER

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1986.tb20861.x

  3. PART III. PROPERTIES OF AUTOANTIBODIES

    1. Top of page
    2. PART I. GENETICS OF AUTOIMMUNITY
    3. PART II. IDIOTYPE NETWORK
    4. PART III. PROPERTIES OF AUTOANTIBODIES
    5. PART IV. ORIGINS OF AUTOANTIBODIES
    6. PART V. NEW FORMS OF THERAPY
    7. POSTER PAPERS
    8. Experimental Allergic Orchitis in Mice
    1. Monoclonal Autoantibodies That React with Multiple Organs Basis for Reactivity (pages 123–134)

      ABNER LOUIS NOTKINS and BELLUR S. PRABHAKAR

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1986.tb20862.x

    2. Natural Autoantibodies Constitute a Substantial Part of Normal Circulating Immunoglobulins (pages 135–145)

      G. DIGHIERO, P. LYMBERI, B. GUILBERT, T. TERNYNCK and S. AVRAMEAS

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1986.tb20863.x

    3. Postinfectious Autoimmunity: Two Distinct Phases of Coxsackievirus B3-Induced Myocarditis (pages 146–156)

      NOEL R. ROSE, LUANNE J. WOLFGRAM, AHVIE HERSKOWITZ and KIRK W. BEISEL

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1986.tb20864.x

    4. Monoclonal Antibody Studies Defining the Origin and Properties of Autoantibodies in Graves' Disease (pages 157–173)

      LEONARD D. KOHN, FRANCISCO ALVAREZ, CLAUDIO MARCOCCI, ANDREA D. KOHN, DANIELA CORDA, WILLIAM E. HOFFMAN, DONATELLA TOMBACCINI, WILLIAM A. VALENTE, MICHELE DE LUCA, PILAR SANTISTEBAN and EVELYN F. GROLLMAN

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1986.tb20865.x

    5. Speculation on the Role of Somatic Mutation in the Generation of Anti-DNA Antibodies (pages 174–179)

      ANNE DAVIDSON, ROBERTA HALPERN and BETTY DIAMOND

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1986.tb20866.x

    6. Human Pemphigus Autoantibodies Are Pathogenic to Squamous Epithelium (pages 181–190)

      LUIS A. DIAZ, JUSTIN T. ROSCOE, N. FRED EAGLSTEIN, RAMSY S. LABIB, HARISH P. PATEL, DIYA F. MUTASIM and GRANT J. ANHALT

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1986.tb20867.x

  4. PART IV. ORIGINS OF AUTOANTIBODIES

    1. Top of page
    2. PART I. GENETICS OF AUTOIMMUNITY
    3. PART II. IDIOTYPE NETWORK
    4. PART III. PROPERTIES OF AUTOANTIBODIES
    5. PART IV. ORIGINS OF AUTOANTIBODIES
    6. PART V. NEW FORMS OF THERAPY
    7. POSTER PAPERS
    8. Experimental Allergic Orchitis in Mice
    1. Monoclonal Anti-DNA Antibodies The Targets and Origins of SLE Autoantibodies (pages 192–199)

      B. DAVID STOLLAR and ROBERT S. SCHWARTZ

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1986.tb20868.x

    2. Studies of the Effects of Y Chromosome Factors on the Expression of Autoimmune Disease (pages 200–218)

      ALFRED D. STEINBERG, KATHLEEN H. TRIEM, HOWARD R. SMITH, CARL A. LASKIN, YVONNE J. ROSENBERG, DENNIS M. KLINMAN, J. FREDERIC MUSHINSKI and JOHN D. MOUNTZ

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1986.tb20869.x

    3. The Auto-Anti-Idiotypic Route to Antireceptor Antibodies (pages 219–226)

      BERNARD F. ERLANGER, W. L. CLEVELAND, N. H. WASSERMANN, H. H. KU, B. L. HILL, K. K. WAN, R. SARANGARAJAN and A. S. PENN

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1986.tb20870.x

    4. The Questionable Role of Anti-DNA Antibodies in the Pathogenesis of Systemic Lupus Erythematosus (pages 231–240)

      JEAN-FRANÇOIS BACH, LAURENT JACOB, GILLES FEUTREN and FRANÇOIS TRON

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1986.tb20872.x

    5. HLA-D/DR Expression on Epithelial Cells: The Finger on the Trigger? (pages 241–250)

      I. TODD, M. LONDEI, R. PUJOL, R. MIRAKIAN, M. FELDMANN and G. F. BOTTAZZO

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1986.tb20873.x

    6. Ia Antigen Expression and Autoimmunity in MRL-lpr/lpr Mice (pages 251–266)

      YVONNE J. ROSENBERG, PAUL K. GOLDSMITH, JUNICHI OHARA, ALFRED D. STEINBERG and WILLIAM OHRINER

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1986.tb20874.x

  5. PART V. NEW FORMS OF THERAPY

    1. Top of page
    2. PART I. GENETICS OF AUTOIMMUNITY
    3. PART II. IDIOTYPE NETWORK
    4. PART III. PROPERTIES OF AUTOANTIBODIES
    5. PART IV. ORIGINS OF AUTOANTIBODIES
    6. PART V. NEW FORMS OF THERAPY
    7. POSTER PAPERS
    8. Experimental Allergic Orchitis in Mice
    1. Therapy of Autoimmune Diseases with Antibody to Immune Response Gene Products or to T-Cell Surface Markers (pages 274–284)

      LAWRENCE STEINMAN, MATTHEW K. WALDOR, SCOTT S. ZAMVIL, MAE LIM, LEANORE HERZENBERG, LEONARD HERZENBERG, HUGH O. McDEVITT, DENNIS MITCHELL and SUBRAMANIAM SRIRAM

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1986.tb20876.x

    2. Treatment of Autoimmune Disease with Total Lymphoid Irradiation Cellular and Humoral Mechanisms (pages 285–295)

      S. STROBER, B. KOTZIN, E. FIELD, R. HOPPE, B. MYERS and A. TANAY

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1986.tb20877.x

    3. A Possible New Therapy of Systemic Lupus Erythematosus (SLE) (pages 296–306)

      H. BOREL, D. BASTIAN, B. COOPER and Y. BOREL

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1986.tb20878.x

    4. Cyclosporine as a New Approach to Therapy of Autoimmune Diseases (pages 307–319)

      J. F. BOREL and H. C. GUNN

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1986.tb20879.x

    5. Hormonal Approaches to Immunotherapy of Autoimmune Disease (pages 320–328)

      NORMAN TALAL, S. ANSAR AHMED and MICHAEL DAUPHINEE

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1986.tb20880.x

  6. POSTER PAPERS

    1. Top of page
    2. PART I. GENETICS OF AUTOIMMUNITY
    3. PART II. IDIOTYPE NETWORK
    4. PART III. PROPERTIES OF AUTOANTIBODIES
    5. PART IV. ORIGINS OF AUTOANTIBODIES
    6. PART V. NEW FORMS OF THERAPY
    7. POSTER PAPERS
    8. Experimental Allergic Orchitis in Mice
    1. Experimental Autoimmune Uveitis (EAU) An Anti-Idiotypic Antibody Study (pages 329–330)

      CARMEN F. MERRYMAN and LARRY A. DONOSO

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1986.tb20881.x

    2. BALB/c Substrain Differences in Susceptibility to Experimental Allergic Encephalomyelitis (EAE) (pages 331–333)

      WILLIAM F. HICKEY, WILLIAM M. KIRBY and CORY TEUSCHER

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1986.tb20882.x

  7. Experimental Allergic Orchitis in Mice

    1. Top of page
    2. PART I. GENETICS OF AUTOIMMUNITY
    3. PART II. IDIOTYPE NETWORK
    4. PART III. PROPERTIES OF AUTOANTIBODIES
    5. PART IV. ORIGINS OF AUTOANTIBODIES
    6. PART V. NEW FORMS OF THERAPY
    7. POSTER PAPERS
    8. Experimental Allergic Orchitis in Mice
    1. Characterization of the Antigen of Human Antitubular Basement Membrane Antibody-Associated Interstitial Nephritis (pages 336–337)

      M. CLAYMAN, L. MICHAUD, J. BRENTJENS, G. ANDRES and E. G. NEILSON

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1986.tb20884.x

    2. Induction of Type II Collagen Autoimmune Arthritis and Ear Disease in Monkey (pages 341–342)

      T. J. YOO, J. M. STUART, T. TAKEDA, N. SUDO, R. A. FLOYD, T. ISHIBE, G. OLSON, D. ORCHIK, J. J. SHEA and A. H. KANG

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1986.tb20886.x

    3. A Guinea Pig Model of Autoimmune Endolymphatic Hydrops (pages 343–344)

      T. J. YOO, N. SUDO, Y. YAZAWA, R. A. FLOYD, T. ISHIBE and T. TAKEDA

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1986.tb20887.x

    4. Increased Thromboplastin Production in Multiple Sclerosis: An Immunologic Defect? (pages 345–346)

      CHARLES R. SPILLERT, MARINO P. HAFSTEIN, VENKATA LANKA and ERIC J. LAZARO

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1986.tb20888.x

    5. Immunological Studies of the Prostate (pages 347–349)

      RICHARD J. ABLIN, RACHEL STEIN, JOHN M. BARTKUS and MAURICE J. GONDER

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1986.tb20889.x

    6. Treatment of Diabetic (db/db) Mice with Anti-Class-II MHC Monoclonal Antibodies (pages 353–355)

      BHAGIRATH SINGH and WILLIAM J. CLIFFE

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1986.tb20891.x

    7. In Insulin-Dependent Diabetes, the Expression of an HLA-DR4-Related Susceptibility Gene Is Dominant, but Expression of a DR3-Related Gene Is Dependent on the DR4-Related Gene (pages 356–358)

      MICHAEL J. MACDONALD, JERRY GOTTISCHALL, JAY B. HUNTER, KAREN L. WINTER, STEVEN D. JOHNSON, JUDITH L. BLANK, ELIZABETH P. MASON and SHARON MABY

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1986.tb20892.x

    8. Aberrant Expression of HLA-DR Determinants on Human Thyroid Cells Treated with Phytohemagglutinin and γ-Interferon and on Human Melanoma Cells Demonstration with a Binding Assay Using a New Potent 125I-Monoclonal Antibody against the HLA-DR β-Chain (MAb 03-D7) (pages 359–360)

      P. DE MEYTS, S. HALLEZ, J. L. GU, M. MERCHEZ, I. ECONOMIDIS, G. G. ROUSSEAU, J. van SNICK, C. SPINEL, J. P. SQUIFFLET, A. M. RAVOET, M. de BRUYERE, K. WILLARD, F. VESSIERE, C. LEMOINE, T. BOON, H. TOYODA, F. CHEN and J. SHIVELY

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1986.tb20893.x

    9. Immunogenetics of Collagen-Induced Arthritis (CIA) in Mice A Model of Autoimmune Disease (pages 361–363)

      H. S. LUTHRA, P. H. WOOLEY, A. DILLON, S. K. SINGH, W. P. LAFUSE, C. J. KRCO, A. HUSE, J. M. STUART, M. M. GRIFFITHS and C. S. DAVID

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1986.tb20894.x

    10. A Prototype Anti-DNA Autoantibody Appears to Define a New VH Gene That Is Conserved in Many Strains of Mice (pages 364–365)

      KATHLEEN J. BARRETT and WILLIAM TREPICCHIO JR

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1986.tb20895.x

    11. Hybridoma Lupus Anticoagulants Distinguish between Bilayer and Nonbilayer Phase Lipid Systems (pages 366–369)

      J. RAUCH, M. TANNENBAUM, H. TANNENBAUM, H. RAMELSON, P. R. CULLIS, C. P. S. TILCOCK, M. J. HOPE and A. S. JANOFF

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1986.tb20896.x

    12. Demonstration of Lupus Anticoagulant Antigens Using an Enzyme-Linked Immunoadsorbent Assay (ELISA) (pages 370–372)

      D. WARE BRANCH, NEAL S. ROTE and JAMES R. SCOTT

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1986.tb20897.x

    13. Thrombocytopenia in Pregnancy-Induced Hypertension IgG and IgM on Maternal and Umbilical Cord Platelets (pages 373–375)

      NEAL S. ROTE, MARK HARRISON, R. JANE LAU and JAMES R. SCOTT

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1986.tb20898.x

    14. Cross-Reactive Idiotypes in IgA-Deficient Sera (pages 376–379)

      C. CUNNINGHAM-RUNDLES, M. K. L. CHEUNG and J. KOISTINEN

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1986.tb20899.x

    15. Divergence of the Role of Acute Phase Protein Responses in Autoimmune Strains of Mice (pages 380–382)

      MARY JO STARUCH and FRANCIS J. DUMONT

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1986.tb20900.x

    16. Alterations of the Lyt-2+ T-Cell Population in Murine Systemic Autoimmunity (pages 383–385)

      FRANCIS J. DUMONT, ROBERT C. HABBERSETT and JACQUELINE A. TREFFINGER

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1986.tb20901.x

    17. Restricted Heterogeneity and T-cell Dependence of Human Thyroid Autoantibody IgG Subclasses (pages 386–388)

      T. F. DAVIES, C. M. WEBER, P. WALLACK and M. PLATZER

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1986.tb20902.x

    18. Production of Antibodies against Sm and RNP Antigens in Rabbits (pages 389–390)

      M. ISHAQ and R. ALI

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1986.tb20903.x

    19. HLA-DR Gene Expression in Human Thyroid Tissue and Cultured Human Thyroid Cells (pages 391–394)

      L. A. PICCININI, B. S. SCHACHTER, S. DURGERIAN and T. F. DAVIES

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1986.tb20904.x

    20. Functional Properties of the A3 and B1 Allotypes of Human C4 and Their Possible Relationship to Systemic Lupus Erythematosus (pages 395–398)

      YUN-HUA WONG, CHOONG Y. HAN, PAMELA D. HALE, VERNA M. SKANES and PAUL LEVINE

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1986.tb20905.x

    21. Anti-Myelin Basic Protein Autoreactive T Lymphocytes in Healthy Subjects and Multiple Sclerosis Patients (pages 404–406)

      ELISABETH TOURNIER-LASSERVE, CLAUDE JACQUE, DIDIER FRADELIZI and MARIE-ANNE BACH

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1986.tb20908.x

    22. Studies on Collagen II Induced Arthritis in Mice and Rats (pages 407–408)

      LARS KLARESKOG, RIKARD HOLMDAHL, KRISTOFER RUBIN and HANS WIGZELL

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1986.tb20909.x

    23. Autoantibody Inducing T-Cell Lines with Atypical MHC Restriction (pages 409–410)

      Y. NAPARSTEK, M. P. MADAIO, K. BAUR, L. BREITMAN and R. S. SCHWARTZ

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1986.tb20910.x

    24. Is There a Role for Antibody in the Pathogenesis of Spontaneous Diabetes in the BB Rat? (pages 411–412)

      STEPHEN J. PROWSE, DONALD BELLGRAU and KEVIN J. LAFFERTY

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1986.tb20911.x

    25. Antibodies to an Mr 64,000 Human Islet Cell Protein in the Prediabetic Period of IDDM Patients (pages 415–417)

      S. BAKKESKOV, J. BRUINING, S. SRIKANTA, T. MANDRUP, C. DE BEAUFORT, G. EISENBARTH, J. NERUP and Å. LERNMARK

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1986.tb20913.x

    26. Modulation of a Subset of CD4 (T4) “T Helper” Cells in Active Multiple Sclerosis (MS) and Experimental Allergic Encephalomyelitis (EAE) in Macaques (pages 418–419)

      L. M. ROSE, E. A. CLARK, A. GINSBERG, J. A. LEDBETTER, S. HRUBY and E. C. ALVORD JR.

      Version of Record online: 16 DEC 2006 | DOI: 10.1111/j.1749-6632.1986.tb20914.x

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