Annals of the New York Academy of Sciences

Cover image for Annals of the New York Academy of Sciences

December 1987

Volume 514 Mechanisms of Chemical-Induced Porphyrinopathies

Pages ix–x, 1–352

    1. Preface (pages ix–x)

      ELLEN K. SILBERGELD and BRUCE A. FOWLER

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1987.tb48753.x

    2. Mechanisms of Chemical-Induced Porphyrinopathies Introductory Comments (pages 1–6)

      ATTALLAH KAPPAS

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1987.tb48754.x

  1. PART I. REGULATION OF HEME AND PORPHYRIN METABOLISM

    1. Top of page
    2. PART I. REGULATION OF HEME AND PORPHYRIN METABOLISM
    3. PART II. MECHANISMS OF METAL-INDUCED PORPHYRINOPATHIES
    4. PART III. MECHANISMS OF HALOGENATED ORGANIC-INDUCED PORPHYRINOPATHIES
    5. PART IV. PORPHYRINS AS INDICATORS OF CHEMICAL INJURY AND EXPOSURE
    6. PART V. FACTORS INFLUENCING ALTERATIONS IN HEME METABOLISM AND FUNCTION
    7. PART VI. PORPHYRINOPATHIES IN CHEMICAL-INDUCED DISEASE STATES INVOLVING SPECIFIC ORGAN SYSTEMS
    8. POSTER PAPERS
    1. Zinc Protoporphyrin Past, Present, and Future (pages 7–14)

      ROBERT F. LABBÉ, REBECCA L. RETTMER, ALKA G. SHAH and JUDITH R. TURNLUND

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1987.tb48755.x

    2. Genetic Regulation of the Heme Pathway (pages 15–22)

      SHIGERU SASSA, HIROYOSHI FUJITA and OSAMU SUGITA

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1987.tb48756.x

    3. δ-Aminolevulinic Acid Dehydratase Isozymes and Lead Toxicity (pages 23–29)

      K. H. ASTRIN, D. F. BISHOP, J. G. WETMUR, B. KAUL, B. DAVIDOW and R. J. DESNICK

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1987.tb48757.x

  2. PART II. MECHANISMS OF METAL-INDUCED PORPHYRINOPATHIES

    1. Top of page
    2. PART I. REGULATION OF HEME AND PORPHYRIN METABOLISM
    3. PART II. MECHANISMS OF METAL-INDUCED PORPHYRINOPATHIES
    4. PART III. MECHANISMS OF HALOGENATED ORGANIC-INDUCED PORPHYRINOPATHIES
    5. PART IV. PORPHYRINS AS INDICATORS OF CHEMICAL INJURY AND EXPOSURE
    6. PART V. FACTORS INFLUENCING ALTERATIONS IN HEME METABOLISM AND FUNCTION
    7. PART VI. PORPHYRINOPATHIES IN CHEMICAL-INDUCED DISEASE STATES INVOLVING SPECIFIC ORGAN SYSTEMS
    8. POSTER PAPERS
    1. Occurrence and Biological Properties of N-Methyl Protoporphyrin (pages 30–40)

      FRANCESCO DE MATTEIS, ANTHONY H. GIBBS and ANN E. HOLLEY

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1987.tb48758.x

    2. Metal-Induced Alterations of δ-Aminolevulinic Acid Dehydratase (pages 41–47)

      ALFRED BERNARD and ROBERT LAUWERYS

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1987.tb48759.x

    3. Effect of Lead on Uroporphyrin and Heme Content in the Bone Marrow of Rats Exposed to Nitrous Oxide (pages 48–54)

      WALTER N. PIPER and W. RUSS CHRISTENSON

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1987.tb48760.x

    4. Metal Alteration of Uroporphyrinogen Decarboxylase and Coproporphyrinogen Oxidase (pages 55–64)

      JAMES S. WOODS and BRUCE A. FOWLER

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1987.tb48761.x

    5. Metal Induction of Heme Oxygenase (pages 65–80)

      F. WILLIAM SUNDERMAN JR.

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1987.tb48762.x

    6. Metal Inhibition of Ferrochelatase (pages 81–86)

      HARRY A. DAILEY

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1987.tb48763.x

    7. Control of Heme Metabolism by Synthetic Metalloporphyrins (pages 87–95)

      GEORGE S. DRUMMOND

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1987.tb48764.x

  3. PART III. MECHANISMS OF HALOGENATED ORGANIC-INDUCED PORPHYRINOPATHIES

    1. Top of page
    2. PART I. REGULATION OF HEME AND PORPHYRIN METABOLISM
    3. PART II. MECHANISMS OF METAL-INDUCED PORPHYRINOPATHIES
    4. PART III. MECHANISMS OF HALOGENATED ORGANIC-INDUCED PORPHYRINOPATHIES
    5. PART IV. PORPHYRINS AS INDICATORS OF CHEMICAL INJURY AND EXPOSURE
    6. PART V. FACTORS INFLUENCING ALTERATIONS IN HEME METABOLISM AND FUNCTION
    7. PART VI. PORPHYRINOPATHIES IN CHEMICAL-INDUCED DISEASE STATES INVOLVING SPECIFIC ORGAN SYSTEMS
    8. POSTER PAPERS
    1. Role of Cytochrome P-450 in Porphyria Caused by Halogenated Aromatic Compounds (pages 96–112)

      HERBERT L. BONKOVSKY, PETER R. SINCLAIR, W. JAY BEMENT, RICHARD W. LAMBRECHT and JACQUELINE F. SINCLAIR

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1987.tb48765.x

    2. Patterns of Porphyrin Accumulation in Response to Xenobiotics Parallels between Results in Chick Embryo and Rodents (pages 113–127)

      GERALD S. MARKS, JANE POWLES, MARTHA LYON, STUART McCLUSKEY, ELAINE SUTHERLAND and DAVID ZELT

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1987.tb48766.x

    3. Effects of Chlorinated Organics on Intermediates in the Heme Pathway and on Uroporphyrinogen Decarboxylase (pages 128–140)

      LAVINIA CANTONI, MILENA RIZZARDINI, ANDREA GRAZIANI, CARMEN CARUGO and SILVIO GARATTINI

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1987.tb48767.x

    4. Alterations of Uroporphyrinogen Decarboxylase by Chlorinated Organics (pages 141–147)

      G. H. ELDER, A. G. ROBERTS and A. J. URQUHART

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1987.tb48768.x

    5. Inhibitory Effect of Tetrachloro-p-Hydroquinone and Other Metabolites of Hexachlorobenzene on Hepatic Uroporphyrinogen Decarboxylase Activity with Reference to the Role of Glutathione (pages 148–159)

      GÜNTER KOSS, MARGA LOSEKAM, JUTTA SEIDEL, KLAUS STEINBACH and WOLFGANG KORANSKY

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1987.tb48769.x

    6. Biochemical Studies on Griseofulvin-Induced Protoporphyria (pages 160–169)

      TOKIO SHIMOYAMA and SHIGEO NONAKA

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1987.tb48770.x

  4. PART IV. PORPHYRINS AS INDICATORS OF CHEMICAL INJURY AND EXPOSURE

    1. Top of page
    2. PART I. REGULATION OF HEME AND PORPHYRIN METABOLISM
    3. PART II. MECHANISMS OF METAL-INDUCED PORPHYRINOPATHIES
    4. PART III. MECHANISMS OF HALOGENATED ORGANIC-INDUCED PORPHYRINOPATHIES
    5. PART IV. PORPHYRINS AS INDICATORS OF CHEMICAL INJURY AND EXPOSURE
    6. PART V. FACTORS INFLUENCING ALTERATIONS IN HEME METABOLISM AND FUNCTION
    7. PART VI. PORPHYRINOPATHIES IN CHEMICAL-INDUCED DISEASE STATES INVOLVING SPECIFIC ORGAN SYSTEMS
    8. POSTER PAPERS
    1. Porphyrins as Indicators of Chemical Injury and Exposure (pages 170–171)

      ELLEN K. SILBERGELD

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1987.tb48771.x

    2. Metal- and Metalloid-Induced Porphyrinurias Relationships to Cell Injury (pages 172–182)

      BRUCE A. FOWLER, AGNETA OSKARSSON and JAMES S. WOODS

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1987.tb48772.x

    3. Turkish Epidemic Hexachlorobenzene Porphyria A 30-Year Study (pages 183–190)

      HENRY PETERS, DEREK CRIPPS, AYHAN GÖCMEN, GEORGE BRYAN, ERDOGAN ERTÜRK and CARL MORRIS

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1987.tb48773.x

    4. Lead Effects on the Heme Biosynthetic Pathway Relationship to Toxicity (pages 191–203)

      MICHAEL R. MOORE, ABRAHAM GOLDBERG and ALBERT A. C. YEUNG-LAIWAH

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1987.tb48774.x

    5. Porphyrinurias and Occupational Disease (pages 204–218)

      MANFRED O. DOSS

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1987.tb48775.x

    6. Porphyrins in Urine as an Indication of Exposure to Chlorinated Hydrocarbons (pages 219–221)

      J. J. T. W. A. STRIK

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1987.tb48776.x

    7. Mechanism of PCB-Induced Porphyria and Yusho Disease (pages 222–234)

      YOSHIHIKO SEKI, SHOSUKE KAWANISHI and SEIYO SANO

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1987.tb48777.x

  5. PART V. FACTORS INFLUENCING ALTERATIONS IN HEME METABOLISM AND FUNCTION

    1. Top of page
    2. PART I. REGULATION OF HEME AND PORPHYRIN METABOLISM
    3. PART II. MECHANISMS OF METAL-INDUCED PORPHYRINOPATHIES
    4. PART III. MECHANISMS OF HALOGENATED ORGANIC-INDUCED PORPHYRINOPATHIES
    5. PART IV. PORPHYRINS AS INDICATORS OF CHEMICAL INJURY AND EXPOSURE
    6. PART V. FACTORS INFLUENCING ALTERATIONS IN HEME METABOLISM AND FUNCTION
    7. PART VI. PORPHYRINOPATHIES IN CHEMICAL-INDUCED DISEASE STATES INVOLVING SPECIFIC ORGAN SYSTEMS
    8. POSTER PAPERS
    1. Drug-Induced Modulations of Hepatic Heme Metabolism Neurological Consequences (pages 248–255)

      MARIA ALMIRA CORREIA, DAVID A. LITMAN and JENNINE M. LUNETTA

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1987.tb48779.x

    2. Hormonal Regulation of the Heme Pathway (pages 256–260)

      RICHARD A. GALBRAITH

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1987.tb48780.x

  6. PART VI. PORPHYRINOPATHIES IN CHEMICAL-INDUCED DISEASE STATES INVOLVING SPECIFIC ORGAN SYSTEMS

    1. Top of page
    2. PART I. REGULATION OF HEME AND PORPHYRIN METABOLISM
    3. PART II. MECHANISMS OF METAL-INDUCED PORPHYRINOPATHIES
    4. PART III. MECHANISMS OF HALOGENATED ORGANIC-INDUCED PORPHYRINOPATHIES
    5. PART IV. PORPHYRINS AS INDICATORS OF CHEMICAL INJURY AND EXPOSURE
    6. PART V. FACTORS INFLUENCING ALTERATIONS IN HEME METABOLISM AND FUNCTION
    7. PART VI. PORPHYRINOPATHIES IN CHEMICAL-INDUCED DISEASE STATES INVOLVING SPECIFIC ORGAN SYSTEMS
    8. POSTER PAPERS
    1. The Dermatologic Manifestations of Human Porphyria (pages 261–267)

      DAVID R. BICKERS

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1987.tb48781.x

    2. Alterations in Renal Heme Biosynthesis during Metal Nephrotoxicity (pages 268–277)

      AGNETA OSKARSSON and BRUCE A. FOWLER

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1987.tb48782.x

    3. Lead-Induced Abnormalities of Porphyrin Metabolism The Relationship with Iron Deficiency (pages 278–288)

      SERGIO PIOMELLI, CAROL SEAMAN and SHIV KAPOOR

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1987.tb48783.x

    4. Porphyrins and Hepatotoxicity (pages 289–296)

      RENATE D. KIMBROUGH

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1987.tb48784.x

    5. Role of Altered Heme Synthesis in Chemical Injury to the Nervous System (pages 297–308)

      ELLEN K. SILBERGELD

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1987.tb48785.x

    6. Principles for Application of Porphyrin Markers in Epidemiological Studies (pages 323–326)

      PHILIP J. LANDRIGAN

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1987.tb48787.x

    7. Comments on Porphyrin (page 327)

      NORTON NELSON

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1987.tb48788.x

  7. POSTER PAPERS

    1. Top of page
    2. PART I. REGULATION OF HEME AND PORPHYRIN METABOLISM
    3. PART II. MECHANISMS OF METAL-INDUCED PORPHYRINOPATHIES
    4. PART III. MECHANISMS OF HALOGENATED ORGANIC-INDUCED PORPHYRINOPATHIES
    5. PART IV. PORPHYRINS AS INDICATORS OF CHEMICAL INJURY AND EXPOSURE
    6. PART V. FACTORS INFLUENCING ALTERATIONS IN HEME METABOLISM AND FUNCTION
    7. PART VI. PORPHYRINOPATHIES IN CHEMICAL-INDUCED DISEASE STATES INVOLVING SPECIFIC ORGAN SYSTEMS
    8. POSTER PAPERS
    1. Hematoporphyrin Derivative Uptake and Tumor Cell Density (pages 328–329)

      GRETA M. GARBO, RICK W. KECK, STEVEN H. SELMAN and MARTHA KREIMER-BIRN BAUM

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1987.tb48789.x

    2. Mechanism of Urinary Excretion of δ-Aminolevulinic Acid after Intratracheal Instillation of Gallium Arsenide (pages 330–332)

      PETER L. GOERING and BRUCE A. FOWLER

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1987.tb48790.x

    3. Studies on the Role of the Ah Receptor in Hexachlorobenzene-Induced Porphyria (pages 333–334)

      MARK E. HAHN, THOMAS A. GASIEWICZ, PATRICIA LINKO and JOYCE A. GOLDSTEIN

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1987.tb48791.x

    4. Porphyria Cutanea Tarda Manifestation and Therapy (pages 335–336)

      VACLAV KORDAČ, PAVEL MARTÁSEK, VLASTIMIL ZOUBEK and MILAN KALÁB

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1987.tb48792.x

    5. Induction of Acute Attack in Acute Hepatic Porphyrias Experiences with Diagnosis and Therapy over Thirty Years (pages 342–344)

      PAVEL MARTÁSEK, VÁCLAV KORDAČ, MICHAELA KOZÁKOVÁ, MILAN JIRSA, PETR KOTAL and JIŘ I. HORÁK

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1987.tb48795.x

    6. Overcoming the Limitations of Hematofluorometry for Assaying Zinc Protoporphyrin (pages 345–346)

      REBECCA L. RETTMER, ELAINE W. GUNTER and ROBERT F. LABBÉ

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1987.tb48796.x

    7. Evidence for 3,4,3,4-Tetrachlorobiphenyl-Mediated Oxidation of Uroporphyrinogen by Chick Embryo Liver Supernatants (pages 347–348)

      PETER R. SINCLAIR and RICHARD W. LAMBRECHT

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1987.tb48797.x

    8. An Association between Zinc Protoporphyrin Elevation and Recovery from Acute Hematopoietic Damage (pages 349–350)

      THOMAS L. WALDEN JR, HUDA M. AL-ANSARI and WALTER R. FARKAS

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1987.tb48798.x

    9. Index of Contributors (pages 351–352)

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1987.tb48799.x

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