Annals of the New York Academy of Sciences

Cover image for Annals of the New York Academy of Sciences

December 1988

Volume 548 Endocrine, Metabolic and Immunological Functions of Keratinocytes

Pages ix–ix, 1–353

  1. Preface

    1. Top of page
    2. Preface
    3. INTRODUCTORY LECTURE
    4. PART I. ROLE OF KERATINOCYTES IN VITAMIN AND HORMONE BIOGENESIS
    5. PART II. DISTANT EFFECTS OF KERATINOCYTE METABOLISM
    6. Part III. Peptides with Paracrine/Endocrine Actions
    7. Part IV. Peptides with Autocrine Actions
    8. PART V. PEPTIDES WHICH MODULATE THE IMMUNE SYSTEM
    9. PART VI. MULTIFUNCTIONAL PERTIDES FROM KERATINOCYTES
    1. Preface (page ix)

      Leonard M. Milstone

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1988.tb18786.x

  2. INTRODUCTORY LECTURE

    1. Top of page
    2. Preface
    3. INTRODUCTORY LECTURE
    4. PART I. ROLE OF KERATINOCYTES IN VITAMIN AND HORMONE BIOGENESIS
    5. PART II. DISTANT EFFECTS OF KERATINOCYTE METABOLISM
    6. Part III. Peptides with Paracrine/Endocrine Actions
    7. Part IV. Peptides with Autocrine Actions
    8. PART V. PEPTIDES WHICH MODULATE THE IMMUNE SYSTEM
    9. PART VI. MULTIFUNCTIONAL PERTIDES FROM KERATINOCYTES
    1. Effector Functions of Epidermal Keratinocytes (pages 1–3)

      LEONARD M. MILSTONE

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1988.tb18787.x

  3. PART I. ROLE OF KERATINOCYTES IN VITAMIN AND HORMONE BIOGENESIS

    1. Top of page
    2. Preface
    3. INTRODUCTORY LECTURE
    4. PART I. ROLE OF KERATINOCYTES IN VITAMIN AND HORMONE BIOGENESIS
    5. PART II. DISTANT EFFECTS OF KERATINOCYTE METABOLISM
    6. Part III. Peptides with Paracrine/Endocrine Actions
    7. Part IV. Peptides with Autocrine Actions
    8. PART V. PEPTIDES WHICH MODULATE THE IMMUNE SYSTEM
    9. PART VI. MULTIFUNCTIONAL PERTIDES FROM KERATINOCYTES
    1. Lipid-Related Barriers and Gradients in the Epidermis (pages 4–13)

      PETER M. ELIAS and KENNETH R. FEINGOLD

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1988.tb18788.x

    2. Vitamin D Metabolite Production and Function in Keratinocytes (pages 27–44)

      DANIEL D. BIKLE and SREEKUMAR PILLAI

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1988.tb18790.x

    3. Actions of 1α,25-Dihydroxyvitamin D3 on Normal, Psoriatic, and Promoted Epiderma1 Keratinocytes (pages 45–55)

      TOSHIO KUROKI, SHIGETO MORIMOTO and TATSUO SUDA

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1988.tb18791.x

    4. Keratinocytes Convert Thyroxine to Triiodothyronine (pages 56–65)

      MICHAEL M. KAPLAN, PHILIP R. GORDON, CHANGYU PAN, JENN-KUEN LEE and BARBARA A. GILCHREST

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1988.tb18792.x

    5. Steroid Metabolism by Epidermal Keratinocytes (pages 66–89)

      LEON MILEWICH, CYNTHIA B. SHAW and FICHARD D. SONTHEIMER

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1988.tb18793.x

  4. PART II. DISTANT EFFECTS OF KERATINOCYTE METABOLISM

    1. Top of page
    2. Preface
    3. INTRODUCTORY LECTURE
    4. PART I. ROLE OF KERATINOCYTES IN VITAMIN AND HORMONE BIOGENESIS
    5. PART II. DISTANT EFFECTS OF KERATINOCYTE METABOLISM
    6. Part III. Peptides with Paracrine/Endocrine Actions
    7. Part IV. Peptides with Autocrine Actions
    8. PART V. PEPTIDES WHICH MODULATE THE IMMUNE SYSTEM
    9. PART VI. MULTIFUNCTIONAL PERTIDES FROM KERATINOCYTES
    1. Sulfation Reactions of the Epidermis (pages 97–101)

      ERVIN H. EPSTEIN Jr., ALEX W. LANGSTON and JESSICA LEUNG

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1988.tb18795.x

    2. Metabolic Activation of Carcinogens by Keratinocytes (pages 102–106)

      DAVID R. BICKERS

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1988.tb18796.x

    3. Evidence for Fibroblast Heterogeneity (pages 108–114)

      MARC E. GOLDYNE

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1988.tb18797.x

    4. Local and Systemic Implications of Thymidine Catabolism by Human Keratinocytes (pages 115–124)

      PAULINE M. SCHWARTZ, HAIM REUVENI and LEONARD M. MILSTONE

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1988.tb18798.x

    5. Does Catabolism of Stratum Corneum Proteins Yield Functionally Active Molecules? (pages 125–136)

      IAN R. SCOTT, SUSAN RICHARDS, CLIVE HARDING, J. ERYL LIDDELL and C. GERALD CURT

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1988.tb18799.x

  5. Part III. Peptides with Paracrine/Endocrine Actions

    1. Top of page
    2. Preface
    3. INTRODUCTORY LECTURE
    4. PART I. ROLE OF KERATINOCYTES IN VITAMIN AND HORMONE BIOGENESIS
    5. PART II. DISTANT EFFECTS OF KERATINOCYTE METABOLISM
    6. Part III. Peptides with Paracrine/Endocrine Actions
    7. Part IV. Peptides with Autocrine Actions
    8. PART V. PEPTIDES WHICH MODULATE THE IMMUNE SYSTEM
    9. PART VI. MULTIFUNCTIONAL PERTIDES FROM KERATINOCYTES
    1. A Tumor-Secreted Protein Associated with Human Hypercalcemia of Malignancy : Biology and Molecular Biology (pages 137–145)

      MICHAEL ROSENBLATT, MICHAEL P. CAULFIELD, JOHN E. FISHER, NOBORU HORIUCHI, ROBERTA L. MCKEE, SEVGI B. RODAN, MARK A. THIEDE, DAVID D. THOMPSON, J. GREGORY SEEDOR, RUTH E. NUTT, MARK E. GOLDMAN, JANE E. REAGAN, JAY J. LEVY, C. THOMAS GAY, PATRICIA A. DEHAVEN, GORDON J. STREWLER, ROBERT A. NISSENSON, THOMAS L. CLEMENS and GIDEON A. RODAN

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1988.tb18800.x

    2. Characterization of a parathyroid Hormonelike Peptide Secreted by Human Keratinocytes (pages 146–159)

      KARL L. INSOGNA, ANDREW F. STWART, KYOJI IKEDA, MICHAEL CENTRELLA and LEONARD M. MILSONE

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1988.tb18801.x

    3. Epidermal Keratinocytes Secrete Apolipoprotein E (pages 160–166)

      ELIZABETH s. FENJVES, DAVID A. GORDON, DAVID L. WILLIAMS and LORNE B. TAICHMAN

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1988.tb18802.x

    4. Keratinocyte- and Tumor-Derived Inducers of Collagenase (pages 174–179)

      E. A. BAUER, A. P. PENTLAND, A. KRONBERGER, S. M. WILHELM, G. I. GOLDBERG, H. G. WELGUS and A. Z. EISEN

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1988.tb18804.x

    5. Paracrine Stimulation of Melanocytes by Keratinocytes through Basic Fibroblast Growth Factor (pages 180–190)

      R. HALABAN, R. LANGDON, N. BIRCHALL, C. CCUONO, A. BAIRD, G. SCOTT, G. MOELLOMANN and J. MCGUIRE

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1988.tb18805.x

  6. Part IV. Peptides with Autocrine Actions

    1. Top of page
    2. Preface
    3. INTRODUCTORY LECTURE
    4. PART I. ROLE OF KERATINOCYTES IN VITAMIN AND HORMONE BIOGENESIS
    5. PART II. DISTANT EFFECTS OF KERATINOCYTE METABOLISM
    6. Part III. Peptides with Paracrine/Endocrine Actions
    7. Part IV. Peptides with Autocrine Actions
    8. PART V. PEPTIDES WHICH MODULATE THE IMMUNE SYSTEM
    9. PART VI. MULTIFUNCTIONAL PERTIDES FROM KERATINOCYTES
    1. Signal Transduction for Proliferation and Differentiation in Keratinocytes (pages 191–196)

      STUART H. YUSPA, HENRY HENNINGS, ROBERT W. TUCKER, SUSAN JAKEN, ANNE E. KILKENNY and DENNIS R. ROOP

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1988.tb18806.x

    2. Structure and Function of Growth Inhibitory Epidermal Pentapeptide (pages 197–203)

      KJELL ELGJO and KARL L. REICHELT

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1988.tb18807.x

    3. The Epidermal G1-Chalone: An Endogenous Tissue-Specific Inhibitor of Epidermal Cell Proliferation (pages 204–210)

      K. HARTMUT RICHTER, MATTHIAS CLAUSS, WERNER HÖFLE, RUBEN SCHNAPKE and FRIEDRICH MARKS

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1988.tb18808.x

    4. Keratinocytes Produce and Are Regulated by Transforming Growth Factors (pages 211–224)

      MARK R. PITTELKOW, ROBERT J. COFFEY JR. and HAROLD L. MOSES

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1988.tb18809.x

  7. PART V. PEPTIDES WHICH MODULATE THE IMMUNE SYSTEM

    1. Top of page
    2. Preface
    3. INTRODUCTORY LECTURE
    4. PART I. ROLE OF KERATINOCYTES IN VITAMIN AND HORMONE BIOGENESIS
    5. PART II. DISTANT EFFECTS OF KERATINOCYTE METABOLISM
    6. Part III. Peptides with Paracrine/Endocrine Actions
    7. Part IV. Peptides with Autocrine Actions
    8. PART V. PEPTIDES WHICH MODULATE THE IMMUNE SYSTEM
    9. PART VI. MULTIFUNCTIONAL PERTIDES FROM KERATINOCYTES
    1. Immunology and the Skin Current Concepts (pages 225–232)

      B. J. LONGLEY, I. M. BRAVERMAN and RICHARDL L. EDELSON

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1988.tb18810.x

    2. Amino Acid Sequence of Thymopoietin Isolated from Skin (pages 233–240)

      TAPAN K. AUDHYA and GIDEON GOLDSTEIN

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1988.tb18811.x

    3. Biology and Molecular Biology of Epidermal Cell-Derived Thymocyte Activating Factor (pages 241–252)

      DANIEL N. SAUDER, TRACY ARSENAULT, RODERICK c. MCKENZIE, DAWN K. STETSKO and CALVIN B. HARLEY

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1988.tb18812.x

    4. Keratinocyte-Derived Interleukin 3 (pages 253–261)

      THOMAS A. LUGER, ANDREAS KOCK, REINHARD KIRNBAUER, THOMAS SCHWARZ and JOHN c. ANSEL

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1988.tb18813.x

    5. Hematopoietic, Lymphopoietic, and Proinflammatory Cytokines Produced by Human and Murine Keratinocytes (pages 262–270)

      THOMAS S. KUPPER, MARK HOROWITZ, NIXHOLAS BIRCHALL, HITOSHI MIZUTANI, DAVID COLEMAN, JOSEPH McGUIRE, PATRICK FLOOD, STEVEN DOWER and FRANK LEE

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1988.tb18814.x

    6. Effect of Keratinocyte Cytokines on Thy-1+ Dendritic Epidermal Cells (pages 271–282)

      R. TIGELAAR, J. NIXON-FULTON, A. TAKASHIMA, W. KUZIEL, C. TAKIJIRI, J. LEWIS, P. TUCKER and P. BERGSTRESSER

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1988.tb18815.x

    7. Interleukin-1 Alpha mRNA Induced by Cycloheximide, PMA, and Retinoic Acid Is Reduced by Dexamethasone in PAM-212 Keratinocytes (pages 283–290)

      JSEPH MCGUIRE, ROBERT LANGDON, NICHOLAS BIRCHALL and THOMAS KUPPER

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1988.tb18816.x

  8. PART VI. MULTIFUNCTIONAL PERTIDES FROM KERATINOCYTES

    1. Top of page
    2. Preface
    3. INTRODUCTORY LECTURE
    4. PART I. ROLE OF KERATINOCYTES IN VITAMIN AND HORMONE BIOGENESIS
    5. PART II. DISTANT EFFECTS OF KERATINOCYTE METABOLISM
    6. Part III. Peptides with Paracrine/Endocrine Actions
    7. Part IV. Peptides with Autocrine Actions
    8. PART V. PEPTIDES WHICH MODULATE THE IMMUNE SYSTEM
    9. PART VI. MULTIFUNCTIONAL PERTIDES FROM KERATINOCYTES
    1. Hemopoietins: Roles in Inflammation, Allergy and Neoplasia] (pages 291–298)

      JOHN W. SCHRADER

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1988.tb18817.x

    2. Expression of THY-1 Protein by Murine Keratinocytes (pages 331–332)

      D. A. CHAMBERS, R. L. COHEN, S. F. MARSCHALL, P. S. JACOBSON and M. S. OSTREGA

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1988.tb18821.x

    3. Role of TPA-Inducible Keratinocyte Collagenase in Extracellular Collagen Breakdown (pages 333–335)

      H. Y. LIN, B. BIRKEDAL-HANSEN and H. BIRKEDAL-HANSEN

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1988.tb18822.x

    4. An Effect of Sunscreens on Cutaneous Vitamin D3 Synthesis (pages 336–340)

      L. Y. MATSUOKA, J. WORTSMAN, J. MACLAUGHLIN and M. HOLICK

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1988.tb18823.x

    5. Characterization of Keratinocyte Chemotaxis and Adhesion (pages 344–345)

      A. SANK, N. MARTINET and G. MARTIN

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1988.tb18825.x

    6. Presence of Interleukin-1 Receptors on Keratinocytes (pages 346–347)

      K. PAGANELLI PARKER, D. N. SAUDER and PATRICIA L. KILIAN

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1988.tb18826.x

    7. Epidermal-Derived Lymphokines and Their Presence in Allergic and Irritant Skin Reactions (pages 348–349)

      KRISTIAN THESTRUP-PEDERSEN, CHRISTIAN GRøNHøJ LARSEN, THOMAS TERNOWITZ and CLAUS ZACHARIAE

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1988.tb18827.x

    8. Description of an Epidermal Lymphocyte Chemotactic Factor Which Specifically Attracts OKT4-Positive Lymphocytes (pages 350–351)

      CLAUS ZACHARIAE, THOMAS TERNOWITZ, CHRISTIAN GRØNHØJ LARSEN and KRISTIAN THESTRUP-PEDERSEN

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1988.tb18828.x

    9. Protein Kinase C-Mediated Expression of Transforming Growth Factor-α in Normal Human Keratinocytes (pages 352–353)

      MARK R. PITTELKOW and ROBERT J. COFFEY Jr.

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1988.tb18829.x

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