Annals of the New York Academy of Sciences

Cover image for Annals of the New York Academy of Sciences

April 1991

Volume 615 Tuberous Sclerosis and Allied Disorders: Clinical, Cellular, and Molecular Studies

Pages xi–xii, 1–385

    1. Preface (pages xi–xii)

      William G. Johnson and Manuel R. Gomez

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1991.tb37741.x

  1. Part 1. Clinical Phenotypes of Tuberous Sclerosis

    1. Top of page
    2. Part 1. Clinical Phenotypes of Tuberous Sclerosis
    3. Part 2. Imaging in Tuberous Sclerosis
    4. Part 3. Epidemiology of Tuberous Sclerosis
    5. Part 4. Histopathology and Biochemical Pathology of Tuberous Sclerosis
    6. Part 5. Cell Biology, Neuronal Migrations, and Tuberous Sclerosis
    7. Part 6. Cytogenetics in Tuberous Sclerosis
    8. Part 7. Linkage Analysis of Tuberous Sclerosis
    9. Part 8. Molecular Biology of the Other Phakomatoses
    10. Part 9. Poster Papers
    1. Nervous System And Retinal Involvement

      Phenotypes of the Tuberous Sclerosis Complex with a Revision of Diagnostic Criteria (pages 1–7)

      MANUEL R. GOMEZ

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1991.tb37742.x

    2. Neuropsychiatric Aspects of Tuberous Sclerosis (pages 8–16)

      P. CURATOLO, R. CUSMAI, F. CORTESI, C. CHIRON, I. JAMBAQUE and O. DULAC

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1991.tb37743.x

    3. Ophthalmic Manifestations of Tuberous Sclerosis (pages 17–25)

      DENNIS M. ROBERTSON

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1991.tb37744.x

    4. Extraneural Manifestations

      History and Significance of White Macules, Earliest Visible Sign of Tuberous Sclerosis (pages 26–35)

      THOMAS B. FITZPATRICK

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1991.tb37745.x

    5. Renal Involvement in Tuberous Sclerosis (pages 36–49)

      JAY BERNSTEIN and THOMAS O. ROBBINS

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1991.tb37746.x

    6. Cardiac Rhabdomyomas in Tuberous Sclerosis (pages 50–57)

      G. H. WATSON

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1991.tb37747.x

    7. Cardiac, Pulmonary, and Vascular Involvements in Tuberous Sclerosis (pages 58–70)

      J. T. LIE

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1991.tb37748.x

    8. Hamartomatous Rectal Polyps Are Common in Tuberous Sclerosis (pages 71–80)

      STUART R. GOULD

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1991.tb37749.x

  2. Part 2. Imaging in Tuberous Sclerosis

    1. Top of page
    2. Part 1. Clinical Phenotypes of Tuberous Sclerosis
    3. Part 2. Imaging in Tuberous Sclerosis
    4. Part 3. Epidemiology of Tuberous Sclerosis
    5. Part 4. Histopathology and Biochemical Pathology of Tuberous Sclerosis
    6. Part 5. Cell Biology, Neuronal Migrations, and Tuberous Sclerosis
    7. Part 6. Cytogenetics in Tuberous Sclerosis
    8. Part 7. Linkage Analysis of Tuberous Sclerosis
    9. Part 8. Molecular Biology of the Other Phakomatoses
    10. Part 9. Poster Papers
    1. Imaging of Intracranial Tuberous Sclerosis (pages 81–93)

      O. WAYNE HOUSER, CHARLES W. SHEPHERD and MANUEL R. GOMEZ

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1991.tb37750.x

    2. Imaging of Tuberous Sclerosis Lesions Outside of the Central Nervous System (pages 94–111)

      ALAN D. HOFFMAN

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1991.tb37751.x

    3. Diagnosis of Symptomatic and Asymptomatic Gene Carriers of Tuberous Sclerosis by CCT and MRI (pages 112–122)

      E. S. ROACH, JEFFREY KERR, DIANNE MENDELSOHN, D. WAYNE LASTER and CATHERINE RAESIDE

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1991.tb37752.x

    4. Panel Discussion I: Defining Clinical and Radiologic Criteria Required for the Definitive Diagnosis of Tuberous Sclerosis Complex : Summary of Individual Presentations and Panel Discussion (pages 123–124)

      N. Paul Rosman, John P. Osborne, Manuel R. Gomez, O. Wayne Houser, E. Steve Roach and Charles W. Shepherd

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1991.tb37753.x

  3. Part 3. Epidemiology of Tuberous Sclerosis

    1. Top of page
    2. Part 1. Clinical Phenotypes of Tuberous Sclerosis
    3. Part 2. Imaging in Tuberous Sclerosis
    4. Part 3. Epidemiology of Tuberous Sclerosis
    5. Part 4. Histopathology and Biochemical Pathology of Tuberous Sclerosis
    6. Part 5. Cell Biology, Neuronal Migrations, and Tuberous Sclerosis
    7. Part 6. Cytogenetics in Tuberous Sclerosis
    8. Part 7. Linkage Analysis of Tuberous Sclerosis
    9. Part 8. Molecular Biology of the Other Phakomatoses
    10. Part 9. Poster Papers
    1. Epidemiology of Tuberous Sclerosis (pages 125–127)

      JOHN P. OSBORNE, ALAN FRYER and DAVID WEBB

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1991.tb37754.x

  4. Part 4. Histopathology and Biochemical Pathology of Tuberous Sclerosis

    1. Top of page
    2. Part 1. Clinical Phenotypes of Tuberous Sclerosis
    3. Part 2. Imaging in Tuberous Sclerosis
    4. Part 3. Epidemiology of Tuberous Sclerosis
    5. Part 4. Histopathology and Biochemical Pathology of Tuberous Sclerosis
    6. Part 5. Cell Biology, Neuronal Migrations, and Tuberous Sclerosis
    7. Part 6. Cytogenetics in Tuberous Sclerosis
    8. Part 7. Linkage Analysis of Tuberous Sclerosis
    9. Part 8. Molecular Biology of the Other Phakomatoses
    10. Part 9. Poster Papers
    1. Pathology of Tuberous Sclerosis : Neuropathologic Aspects (pages 128–139)

      EDWARD P. RICHARDSON JR.

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1991.tb37755.x

    2. Cellular Neuropathology of Tuberous Sclerosis (pages 140–148)

      PETER R. HUTTENLOCHER and ROBERT L. WOLLMANN

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1991.tb37756.x

    3. Glycoprotein and Proteoglycan Alterations in Tuberous Sclerosis (pages 149–157)

      ZHILA KHALKHALI-ELLIS, KEIRAN HENDERSON and FRANK W. HEMMING

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1991.tb37757.x

  5. Part 5. Cell Biology, Neuronal Migrations, and Tuberous Sclerosis

    1. Top of page
    2. Part 1. Clinical Phenotypes of Tuberous Sclerosis
    3. Part 2. Imaging in Tuberous Sclerosis
    4. Part 3. Epidemiology of Tuberous Sclerosis
    5. Part 4. Histopathology and Biochemical Pathology of Tuberous Sclerosis
    6. Part 5. Cell Biology, Neuronal Migrations, and Tuberous Sclerosis
    7. Part 6. Cytogenetics in Tuberous Sclerosis
    8. Part 7. Linkage Analysis of Tuberous Sclerosis
    9. Part 8. Molecular Biology of the Other Phakomatoses
    10. Part 9. Poster Papers
    1. Cell Lineage and Cell Migration in the Neural Crest (pages 158–171)

      THOMAS E. LALLIER

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1991.tb37758.x

    2. Cell Adhesion Molecules in Embryogenesis and Disease (pages 172–186)

      KATHRYN L. CROSSIN

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1991.tb37759.x

    3. Cerebral Lesions of Tuberous Sclerosis in Relation to Normal Histogenesis (pages 187–195)

      VERNE S. CAVINESS JR. and TAKAO TAKAHASHI

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1991.tb37760.x

    4. Neuron-Like Cells in Culture of Tuberous Sclerosis Tissue (pages 196–210)

      M. DAVIDSON, H. YOSHIDOME, E. STENROOS and W. G. JOHNSON

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1991.tb37761.x

    5. Origin of the Neuron-Like Cells in Tuberous Sclerosis Tissues (pages 211–219)

      W. G. JOHNSON, H. YOSHIDOME, E.S. STENROOS and M. M. DAVIDSON

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1991.tb37762.x

    6. The Hexabrachion Gene as a Candidate for a Tuberous Sclerosis Gene (pages 220–227)

      JEFF GULCHER and KARI STEFANSSON

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1991.tb37763.x

    7. Abnormal Gene Expressions of Stroma Cells in Patients with Tuberous Sclerosis (pages 228–242)

      YASUMASA ISHIBASHI, RYOJI WATANABE, TOSHITATSU NOGITA, TETSUO TAKAHASHI, KAZUKIYO ONODERA and GENKI KIMURA

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1991.tb37764.x

  6. Part 6. Cytogenetics in Tuberous Sclerosis

    1. Top of page
    2. Part 1. Clinical Phenotypes of Tuberous Sclerosis
    3. Part 2. Imaging in Tuberous Sclerosis
    4. Part 3. Epidemiology of Tuberous Sclerosis
    5. Part 4. Histopathology and Biochemical Pathology of Tuberous Sclerosis
    6. Part 5. Cell Biology, Neuronal Migrations, and Tuberous Sclerosis
    7. Part 6. Cytogenetics in Tuberous Sclerosis
    8. Part 7. Linkage Analysis of Tuberous Sclerosis
    9. Part 8. Molecular Biology of the Other Phakomatoses
    10. Part 9. Poster Papers
  7. Part 7. Linkage Analysis of Tuberous Sclerosis

    1. Top of page
    2. Part 1. Clinical Phenotypes of Tuberous Sclerosis
    3. Part 2. Imaging in Tuberous Sclerosis
    4. Part 3. Epidemiology of Tuberous Sclerosis
    5. Part 4. Histopathology and Biochemical Pathology of Tuberous Sclerosis
    6. Part 5. Cell Biology, Neuronal Migrations, and Tuberous Sclerosis
    7. Part 6. Cytogenetics in Tuberous Sclerosis
    8. Part 7. Linkage Analysis of Tuberous Sclerosis
    9. Part 8. Molecular Biology of the Other Phakomatoses
    10. Part 9. Poster Papers
    1. Locating Disease Genes through Linkage : Special Problems in Working with Tuberous Sclerosis (pages 252–255)

      P. MICHAEL CONNEALLY

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1991.tb37766.x

    2. Genetic Heterogeneity in Tuberous Sclerosis. Study of a Large Collaborative Dataset (pages 256–264)

      J. L. HAINES, J. AMOS, J. ATTWOOD, N. T. BECH-HANSEN, M. BURLEY, P. M. CONNEALLY, J. M. CONNOR, R. FAHSOLD, P. FLODMAN, A. FRYER, D. J. J. HALLEY, A. JEWELL, L. A. J. JANSSEN, R. KANDT, H. NORTHRUP, J. OSBORNE, M. PERICAK-VANCE, S. POVEY, J. SAMPSON, M. P. SHORT, M. SMITH, M. SPEER, J. A. TROFATTER and J. R. W. YATES

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1991.tb37767.x

    3. Recent Linkage Studies in Tuberous Sclerosis : Chromosome 9 Markers (pages 265–273)

      J. MICHAEL CONNOR and JULIAN SAMPSON

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1991.tb37768.x

    4. Genetic Heterogeneity in Tuberous Sclerosis : Map Position of the TSC2 Locus on Chromosome 11q and Future Prospects (pages 274–283)

      MOYRA SMITH, K. YOSHIYAMA, C. WAGNER, P. FLODMAN and B. SMITH

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1991.tb37769.x

    5. Linkage Studies in Tuberous Sclerosis : Chromosome 9?, 11?, or Maybe 14! (pages 284–297)

      R. S. KANDT, M. A. PERICAK-VANCE, W.-Y. HUNG, R. J. M. GARDNER, P. E. CROSSEN, M. D. NELLIST, M. C. SPEER and A. D. ROSES

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1991.tb37770.x

    6. An Attempt to Map Two Genes for Tuberous Sclerosis Using Novel Two-Point Methods (pages 298–305)

      S. POVEY, J. ATTWOOD, L. A. J. JANSSEN, M. BURLEY, M. SMITH, P. FLODMAN, N. E. MORTON, J. H. EDWARDS, J. R. SAMPSON, J. R. W. YATES, J. L. HAINES, J. AMOS, M. P. SHORT, L. A. SANDKUYL, D. J. J. HALLEY, A. E. FRYER, T. BECH-HANSEN, R. MUELLER, L. AL-GHAZALI, M. SUPER and J. OSBORNE

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1991.tb37771.x

    7. A Comparative Study on Genetic Heterogeneity in Tuberous Sclerosis: Evidence for One Gene on 9q34 and a Second Gene on 11q22–23 (pages 306–315)

      L. A. J. JANSSEN, S. POVEY, J. ATTWOOD, L. A. SANDKUYL, D. LINDHOUT, P. FLODMAN, M. SMITH, J. R. SAMPSON, J. L. HAINES, E. C. MERKENS, P. FLEURY, P. SHORT, J. AMOS and D. J. J. HALLEY

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1991.tb37772.x

    8. Panel Discussion II: Linkage Studies in Tuberous Sclerosis : Current Status and Future Prospects (pages 316–318)

      RAYMOND S. KANDT, P. MICHAEL CONNEALLY, J. MICHAEL CONNOR, JONATHAN L. HAINES, MARGARET PERICAK-VANCE and MOYRA SMITH

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1991.tb37773.x

  8. Part 8. Molecular Biology of the Other Phakomatoses

    1. Top of page
    2. Part 1. Clinical Phenotypes of Tuberous Sclerosis
    3. Part 2. Imaging in Tuberous Sclerosis
    4. Part 3. Epidemiology of Tuberous Sclerosis
    5. Part 4. Histopathology and Biochemical Pathology of Tuberous Sclerosis
    6. Part 5. Cell Biology, Neuronal Migrations, and Tuberous Sclerosis
    7. Part 6. Cytogenetics in Tuberous Sclerosis
    8. Part 7. Linkage Analysis of Tuberous Sclerosis
    9. Part 8. Molecular Biology of the Other Phakomatoses
    10. Part 9. Poster Papers
    1. The NF1 Translocation Breakpoint Region (pages 319–331)

      PETER O'CONNELL, RICHARD M. CAWTHON, DAVID VISKOCHIL, RAY WHITE, JOHN C. CAREY and ARTHUR M. BUCHBERG

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1991.tb37774.x

    2. Toward the Isolation of the Primary Genetic Defect in Von Hippel- Lindau Disease (pages 332–337)

      BERND R. SEIZINGER

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1991.tb37775.x

    3. Molecular Genetics of Neurofibromatosis 2 and Related Tumors (Acoustic Neuroma and Meningioma) (pages 338–343)

      BERTRAND FONTAINE, GUY A. ROULEAU, BERND R. SEIZINGER, ANIL G. MENON, ANN F. JEWELL, ROBERT L. MARTUZA and JAMES F. GUSELLA

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1991.tb37776.x

    4. Heterogeneity (pages 344–353)

      J. H. EDWARDS

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1991.tb37777.x

    5. Summary of the Meeting (pages 354–359)

      JOHN EDWARDS

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1991.tb37778.x

  9. Part 9. Poster Papers

    1. Top of page
    2. Part 1. Clinical Phenotypes of Tuberous Sclerosis
    3. Part 2. Imaging in Tuberous Sclerosis
    4. Part 3. Epidemiology of Tuberous Sclerosis
    5. Part 4. Histopathology and Biochemical Pathology of Tuberous Sclerosis
    6. Part 5. Cell Biology, Neuronal Migrations, and Tuberous Sclerosis
    7. Part 6. Cytogenetics in Tuberous Sclerosis
    8. Part 7. Linkage Analysis of Tuberous Sclerosis
    9. Part 8. Molecular Biology of the Other Phakomatoses
    10. Part 9. Poster Papers
    1. Linkage Studies on Tuberous Sclerosis with Probes for Chromosome 11q (page 360)

      F. CORNÉLIS, C. JULIER, A. MALAFOSSE, M. LEBOYER, M. GOSSENS, J. MALLET and M. LATHROP

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1991.tb37779.x

    2. Abnormal Fibronectin Produced in Tuberous Sclerosis (pages 361–362)

      Z. KHALKHALI-ELLIS and F. W. HEMMING

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1991.tb37780.x

    3. Defining the Clinical Phenotype of Von IIippel-Lindau Disease : Experience with a Large Newfoundland Family (pages 363–364)

      J. S. GREEN, T. CUMMINGS, M. BENSE and M. I. BOWMER

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1991.tb37781.x

    4. Estimating “Probability of Tuberous Sclerosis” for Genetic Linkage Studies (pages 365–366)

      NICHOLAS J. LENN

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1991.tb37782.x

    5. Enamel Pitting : A Common Sign of Tuberous Sclerosis (pages 367–369)

      GREG MLYNARCZYK

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1991.tb37783.x

    6. Medical Research and a Tuberous Sclerosis Support Group (pages 370–371)

      DEBBIE FIELDS MURPHY and STEPHEN G. KAHLER

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1991.tb37784.x

    7. Molecular Biology of Cultured Cells from a Patient with Tuberous Sclerosis (pages 372–374)

      K. ONODERA, T. TAKAHASHI, S. ITO, G. KIMURA, R. WATANABE and Y. ISHIBASHI

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1991.tb37785.x

    8. Mortality in the Mayo Clinic Tuberous Sclerosis Complex Study (pages 375–377)

      C. W. SHEPHERD and M. R. GOMEZ

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1991.tb37786.x

    9. Brain Tumors in Tuberous Sclerosis : A Clinicopathologic Study of the Mayo Clinic Experience (pages 378–379)

      C. W. SHEPHERD, B. SCHEITHAUER and M. R. GOMEZ

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1991.tb37787.x

    10. Clinical Findings and Linkage Studies in Familial Tuberous Sclerosis (pages 380–381)

      M. P. SHORT, J. HAINES, A. JEWELL, B. BEJJANI, C. H. YANG, H. WYANDT, H. MacFARLANE, E. ANDERMANN, D. KWIATKOWSKI and J. AMOS

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1991.tb37788.x

    11. Autism and Psychiatric Disorders in Tuberous Sclerosis (pages 382–383)

      SUSAN SMALLEY, M. SMITH and P. TANGUAY

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1991.tb37789.x

    12. Linkage Studies for Markers on 9q to Tuberous Sclerosis (pages 384–385)

      H. NORTHRUP and S. H. BLANTON

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1991.tb37790.x

SEARCH

SEARCH BY CITATION