Annals of the New York Academy of Sciences

Cover image for Annals of the New York Academy of Sciences

September 1993

Volume 694 Saliva as a Diagnostic Fluid

Pages ix–xii, 1–342

    1. Introduction (pages ix–x)

      DANIEL MALAMUD

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1993.tb18334.x

    2. Guidelines for Saliva Nomenclature and Collection (pages xi–xii)

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1993.tb18335.x

    3. Salivary Diagnosis: Promises, Promises (pages 1–10)

      IRWIN D. MANDEL

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1993.tb18336.x

  1. Session I. Principles of Salivary Gland Fluid Secretion/Overview of Pharmacology

    1. Top of page
    2. Session I. Principles of Salivary Gland Fluid Secretion/Overview of Pharmacology
    3. Workshop 1. Methods for Collecting Saliva/Overview of Clinical Pathology
    4. Session II. Drug Monitoring in Saliva
    5. Session III. Hormone Monitoring
    6. Session IV. Salivary Antibodies
    7. Session V. Overview of Salivary Monitoring in Oral Diseases
    8. Workshop 2. Industrial Entries into the Salivary Diagnostic Field
    9. Session V. Overview of Salivary Monitoring in Oral Diseases
    1. Salivary Macromolecules : A Structure/Function Synopsis (pages 11–16)

      MICHAEL J. LEVINE

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1993.tb18337.x

    2. Principles of Saliva Secretion (pages 17–23)

      BRUCE J. BAUM

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1993.tb18338.x

    3. Mechanisms of Fluid Secretion by Salivary Glands (pages 24–35)

      R. JAMES TURNER

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1993.tb18339.x

    4. Pharmacokinetic Principles of Drug Distribution in Saliva (pages 36–47)

      WILLIAM J. JUSKO and REBECCA L. MILSAP

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1993.tb18340.x

    5. Clinical Correlates of Drugs in Saliva (pages 48–61)

      JOHN T. WILSON

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1993.tb18341.x

    6. New Approaches to Monitoring Environmental Neurotoxins (pages 62–71)

      ELLEN K. SILBERGELD

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1993.tb18342.x

  2. Workshop 1. Methods for Collecting Saliva/Overview of Clinical Pathology

    1. Top of page
    2. Session I. Principles of Salivary Gland Fluid Secretion/Overview of Pharmacology
    3. Workshop 1. Methods for Collecting Saliva/Overview of Clinical Pathology
    4. Session II. Drug Monitoring in Saliva
    5. Session III. Hormone Monitoring
    6. Session IV. Salivary Antibodies
    7. Session V. Overview of Salivary Monitoring in Oral Diseases
    8. Workshop 2. Industrial Entries into the Salivary Diagnostic Field
    9. Session V. Overview of Salivary Monitoring in Oral Diseases
    1. Methods for Collecting Saliva (pages 72–77)

      MAHVASH NAVAZESH

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1993.tb18343.x

    2. Fundamental Principles Involved in Developing a New Saliva-based Diagnostic Test (pages 78–85)

      DAVID B. P. GOODMAN

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1993.tb18344.x

  3. Session II. Drug Monitoring in Saliva

    1. Top of page
    2. Session I. Principles of Salivary Gland Fluid Secretion/Overview of Pharmacology
    3. Workshop 1. Methods for Collecting Saliva/Overview of Clinical Pathology
    4. Session II. Drug Monitoring in Saliva
    5. Session III. Hormone Monitoring
    6. Session IV. Salivary Antibodies
    7. Session V. Overview of Salivary Monitoring in Oral Diseases
    8. Workshop 2. Industrial Entries into the Salivary Diagnostic Field
    9. Session V. Overview of Salivary Monitoring in Oral Diseases
    1. The Role of Saliva in Drug Monitoring (pages 86–90)

      IVENS A. SIEGEL

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1993.tb18345.x

    2. Saliva Testing for Drugs of Abuse (pages 91–127)

      EDWARD J. CONE

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1993.tb18346.x

    3. Factors Influencing the Saliva/Plasma Ratio of Drugs (pages 128–142)

      R. HAECKEL

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1993.tb18347.x

  4. Session III. Hormone Monitoring

    1. Top of page
    2. Session I. Principles of Salivary Gland Fluid Secretion/Overview of Pharmacology
    3. Workshop 1. Methods for Collecting Saliva/Overview of Clinical Pathology
    4. Session II. Drug Monitoring in Saliva
    5. Session III. Hormone Monitoring
    6. Session IV. Salivary Antibodies
    7. Session V. Overview of Salivary Monitoring in Oral Diseases
    8. Workshop 2. Industrial Entries into the Salivary Diagnostic Field
    9. Session V. Overview of Salivary Monitoring in Oral Diseases
    1. Steroid Hormone Analysis in Human Saliva (pages 143–145)

      DAVID O. QUISSELL

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1993.tb18348.x

    2. Status Report on Measurement of Salivary Estrogens and Androgens (pages 146–160)

      G. F. READ

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1993.tb18349.x

    3. Measurements of Salivary Progesterone (pages 161–175)

      PETER T. ELLISON

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1993.tb18350.x

    4. Salivary Testosterone Measurements in Behavioral Studies (pages 177–183)

      JAMES M. DABBS JR.

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1993.tb18351.x

  5. Session IV. Salivary Antibodies

    1. Top of page
    2. Session I. Principles of Salivary Gland Fluid Secretion/Overview of Pharmacology
    3. Workshop 1. Methods for Collecting Saliva/Overview of Clinical Pathology
    4. Session II. Drug Monitoring in Saliva
    5. Session III. Hormone Monitoring
    6. Session IV. Salivary Antibodies
    7. Session V. Overview of Salivary Monitoring in Oral Diseases
    8. Workshop 2. Industrial Entries into the Salivary Diagnostic Field
    9. Session V. Overview of Salivary Monitoring in Oral Diseases
    1. Saliva as a Manifestation of the Common Mucosal Immune System (pages 184–194)

      JIRI MESTECKY

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1993.tb18352.x

    2. Practical Applications for Saliva in Perinatal HIV Diagnosis (pages 195–201)

      DAVID W. ARCHIBALD, JOHN J. FARLEY JR., CARLA A. HEBERT, SUSAN E. HINES, PRASANNA NAIR and JOHN P. JOHNSON

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1993.tb18353.x

    3. Significance of Salivary Antibody in Dental Disease (pages 202–215)

      MARTIN A. TAUBMAN and DANIEL J. SMITH

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1993.tb18354.x

  6. Session V. Overview of Salivary Monitoring in Oral Diseases

    1. Top of page
    2. Session I. Principles of Salivary Gland Fluid Secretion/Overview of Pharmacology
    3. Workshop 1. Methods for Collecting Saliva/Overview of Clinical Pathology
    4. Session II. Drug Monitoring in Saliva
    5. Session III. Hormone Monitoring
    6. Session IV. Salivary Antibodies
    7. Session V. Overview of Salivary Monitoring in Oral Diseases
    8. Workshop 2. Industrial Entries into the Salivary Diagnostic Field
    9. Session V. Overview of Salivary Monitoring in Oral Diseases
    1. Salivary Monitoring in Oral Diseases (pages 234–237)

      PHILIP C. FOX

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1993.tb18356.x

    2. The Role of Salivary Measurements in the Diagnosis of Salivary Autoimmune Diseases (pages 238–251)

      JANE C. ATKINSON

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1993.tb18357.x

  7. Workshop 2. Industrial Entries into the Salivary Diagnostic Field

    1. Top of page
    2. Session I. Principles of Salivary Gland Fluid Secretion/Overview of Pharmacology
    3. Workshop 1. Methods for Collecting Saliva/Overview of Clinical Pathology
    4. Session II. Drug Monitoring in Saliva
    5. Session III. Hormone Monitoring
    6. Session IV. Salivary Antibodies
    7. Session V. Overview of Salivary Monitoring in Oral Diseases
    8. Workshop 2. Industrial Entries into the Salivary Diagnostic Field
    9. Session V. Overview of Salivary Monitoring in Oral Diseases
    1. Considerations in the Development of Diagnostic Tests on Saliva (pages 265–269)

      C. DAWES

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1993.tb18359.x

    2. Summary (pages 270–271)

      L. A. TABAK

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1993.tb18360.x

  8. Session V. Overview of Salivary Monitoring in Oral Diseases

    1. Top of page
    2. Session I. Principles of Salivary Gland Fluid Secretion/Overview of Pharmacology
    3. Workshop 1. Methods for Collecting Saliva/Overview of Clinical Pathology
    4. Session II. Drug Monitoring in Saliva
    5. Session III. Hormone Monitoring
    6. Session IV. Salivary Antibodies
    7. Session V. Overview of Salivary Monitoring in Oral Diseases
    8. Workshop 2. Industrial Entries into the Salivary Diagnostic Field
    9. Session V. Overview of Salivary Monitoring in Oral Diseases
    1. Development of a Prototype, Rapid Saliva Test for Hepatitis B Surface Antigen (HBSAg) Utilizing a “Dipstick” Method (pages 272–273)

      R. M. CLEMMONS, C. STEWART, G. DAVIS, C. BEAUDREAU, P. HUMPHREY, C. BROWE and J. SHANDS

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1993.tb18361.x

    2. A New Device for Collection of Parotid Saliva (pages 274–275)

      THORILD ERICSON and ÅKE NORDLUND

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1993.tb18362.x

    3. Relationship of Parotid Saliva C-reactive Protein to Catecholamine Release (pages 276–279)

      R. G. ESQUIRE, E. D. PEDERSON, P. J. COVILL and P. F. SMITH

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1993.tb18363.x

    4. Cystatin C Levels of Whole Saliva Are Increased in Periodontal Patients (pages 280–282)

      YVONNE M. C. HENSKENS, UBELE VAN DER VELDEN, ENNO C. I. VEERMAN and ARIE V. NIEUW AMERONGEN

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1993.tb18364.x

    5. Biochemical Changes in (Glyco)proteins of Saliva of Epileptic Patients (pages 283–285)

      A. V. NIEUW AMERONGEN, H. STROOKER, Y. M. C. HENSKENS, A. J. M. LIGTENBERG and E. C. I. VEERMAN

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1993.tb18365.x

    6. Effect of Postmenopausal Estrogen Treatment on Some Diagnostic Salivary Variables (pages 286–288)

      E-L. HIETALA, J. HEIKKINEN, H. K. VÄÄNÄNEN and M. LARMAS

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1993.tb18366.x

    7. Anti-Hepatitis A in the General Population and in Hepatitis A Vaccinees Using Saliva and Serum as Diagnostic Media (pages 289–292)

      WILLIAM M. HURNI, DAGNA LAUFER, WILLIAM J. MILLER, JOHN RYAN and BARBARA WATSON

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1993.tb18367.x

    8. What Accounts for the Interindividual Variability of sIgA Concentration in Saliva? (pages 296–298)

      JOACHIM KUGLER, MARKUS HESS and DIETMAR HAAKE

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1993.tb18369.x

    9. Pleomorphy of Individual Protein Patterns and Cyclic AMP Reactions in Human Saliva (pages 299–301)

      M. I. MEDNIEKS, E. ZAKI, P. M. EPSTEIN, R. HACHISU, A. R. HAND, J. BODNER and R. G. ESQUIRE

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1993.tb18370.x

    10. Saliva and Dental Caries Risk Assessment (pages 302–304)

      S. A. MUNDORFF, R. J. BILLINGS, D. H. LEVERETT, J. D. B. FEATHERSTONE, L. M. GWINNER, C. P. SHIELDS, H. M. PROSKIN and C. L. SHAFFER

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1993.tb18371.x

    11. Protein Composition, IgG, and IgA Analysis in the Saliva of Patients with Multiple Sclerosis (pages 305–307)

      KATJA PIETZ, JUDITH HAAS and ULRICH WURSTER

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1993.tb18372.x

    12. Immunoreactive Substance P in Human Saliva : A Possible Marker of Chronic Pain (pages 308–310)

      W. C. V. PARRIS, B. V. RAMA SASTRY, J. R. KAMBAM, R. J. NAUKAM and B. W. JOHNSON

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1993.tb18373.x

    13. Methods of Simplified Saliva Collection for the Measurement of Drugs of Abuse, Therapeutic Drugs, and Other Molecules (pages 311–313)

      WILLFRIED SCHRAMM, RICHARD H. SMITH and PAUL A. CRAIG

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1993.tb18374.x

    14. HIV Antibody EIA and Western Blot Assay Results on Paired Serum and Saliva Specimens (page 314)

      D. FITZGIBBONS, G. BARRIGA, E. SEYMOUR and S. STRAMER

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1993.tb18375.x

    15. A Bilateral Collection Device for Noninvasive Monitoring of Drug Levels in Parotid Saliva (pages 317–318)

      MILAN SALVIK, JUN WU, NORMAN BROWN, AMOS WILLIAMS, STEPHEN WAGNER and JANA SLAVIK

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1993.tb18376.x

    16. Salivary Excretion of Anticancer Drugs (pages 319–321)

      MILAN SALVIK, JUN WU and CHRISTOPHER RILEY

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1993.tb18377.x

    17. Von Ebner's Gland : An Immunohistochemical Study (pages 322–324)

      P. D. TOTO, H. NADIMI and R. MARTINEZ

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1993.tb18378.x

    18. Applicability of Saliva as a Diagnostic Fluid in Sjögren's Syndrome (pages 325–326)

      A. VISSINK, A. K. PANDERS, J. M. NAUTA, E. E. LIGEON, P. G. J. NIKKELS and C. G. M. KALLENBERG

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1993.tb18379.x

    19. A Comparative Study of Saliva and OraSure® Oral Fluid (pages 330–331)

      M. L. CORDEIRO, C. S. TURPIN and S. A. McADAMS

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1993.tb18380.x

    20. Detection of Cotinine in Oral Fluid Recovered with the OraSure® Collection System (pages 332–333)

      L. M. NORTH, N. D. GAUDETTE, M. L. CORDEIRO, J. H. FITCHEN, S. L. DAVIDSON and M. S. HINDAHL

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1993.tb18381.x

    21. Diagnosis of Hepatitis A, B, and C Using Oral Samples (pages 334–336)

      STEPHEN C. PIACENTINI, THOMAS R. THIEME, MICHAEL BELLER and SANDRA L. DAVIDSON

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1993.tb18382.x

    22. Therapeutic Drug Monitoring Using Oral Samples Collected with the OraSure® Device (pages 337–339)

      THOMAS THIEME, JOHN FITCHEN, FRANTISEK BARTOS, MARTIN SALINSKY, TERRENCE GREEN and WILLIAM HOLDEN

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1993.tb18383.x

    23. Detection of Antibodies to Helicobacter pylori Using Oral Fluid Specimens (pages 340–342)

      M. G. WIENHOLT, M. C. ERBLING, R. W. BENNETTS, E. A. GALEN and B. M. CIMLER

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1993.tb18384.x

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