Annals of the New York Academy of Sciences

Cover image for Annals of the New York Academy of Sciences

May 1994

Volume 716 Gene Therapy for Neoplastic Diseases

Pages 1–337

    1. Introduction (pages 1–5)

      BRIAN E. HUBER

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb21698.x

  1. The Beginnign: Strategy and Ethics

    1. Top of page
    2. The Beginnign: Strategy and Ethics
    3. Gene Transfer Technology I
    4. Gene Transfer Technology II
    5. Engineering Drug Sensitivity and Drug Resistance: Implications in Cancer Therapy
    6. Immunomodulation through Gene Therapy: Implications for Neoplastic Disease
    7. Implications of Gene Therapy in Bone Marrow Transplantation and Hematopoietic Cells
    8. Other Implications of Gene Therapy Cancer Treatment
    9. Practical Development of Gene Therapy Programs
    10. Poster Papers
    1. Gene Therapy Strategies for Treating Neoplastic Disease (pages 6–11)

      BRIAN E. HUBER

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb21699.x

    2. The Impact of Gene Therapy on Medicine and Society (pages 12–19)

      WILLIAM N. KELLEY

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb21700.x

  2. Gene Transfer Technology I

    1. Top of page
    2. The Beginnign: Strategy and Ethics
    3. Gene Transfer Technology I
    4. Gene Transfer Technology II
    5. Engineering Drug Sensitivity and Drug Resistance: Implications in Cancer Therapy
    6. Immunomodulation through Gene Therapy: Implications for Neoplastic Disease
    7. Implications of Gene Therapy in Bone Marrow Transplantation and Hematopoietic Cells
    8. Other Implications of Gene Therapy Cancer Treatment
    9. Practical Development of Gene Therapy Programs
    10. Poster Papers
    1. Cationic Liposomes for Direct Gene Transfer in Therapy of Cancer and Other Diseases (pages 23–35)

      HASSAN FARHOOD, XIANG GAO, KYONGHEE SON, JOHN S. LAZO, LEAF HUANG, JAMES BARSOUM, REMO BOTTEGA and RICHARD M. EPAND

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb21701.x

  3. Gene Transfer Technology II

    1. Top of page
    2. The Beginnign: Strategy and Ethics
    3. Gene Transfer Technology I
    4. Gene Transfer Technology II
    5. Engineering Drug Sensitivity and Drug Resistance: Implications in Cancer Therapy
    6. Immunomodulation through Gene Therapy: Implications for Neoplastic Disease
    7. Implications of Gene Therapy in Bone Marrow Transplantation and Hematopoietic Cells
    8. Other Implications of Gene Therapy Cancer Treatment
    9. Practical Development of Gene Therapy Programs
    10. Poster Papers
    1. Retroviral Vectors for Use in Human Gene Therapy for Cancer, Gaucher Disease, and Arthritis (pages 72–89)

      PAUL D. ROBBINS, HIDEAKI TAHARA, GUNHILD MUELLER, GREG HUNG, ALFRED BAHNSON, LAURENCE ZITVOGEL, JOANNA GALEA-LAURI, TOYA OHASHI, KEN PATRENE, SALLIE S. BOGGS, CHRISTOPHER H. EVANS, JOHN A. BARRANGER and MICHAEL T. LOTZE

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb21704.x

    2. Adenovirus-Mediated in Vivo Gene Transfer (pages 90–103)

      STEVEN L. BRODY and RONALD G. CRYSTAL

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb21705.x

  4. Engineering Drug Sensitivity and Drug Resistance: Implications in Cancer Therapy

    1. Top of page
    2. The Beginnign: Strategy and Ethics
    3. Gene Transfer Technology I
    4. Gene Transfer Technology II
    5. Engineering Drug Sensitivity and Drug Resistance: Implications in Cancer Therapy
    6. Immunomodulation through Gene Therapy: Implications for Neoplastic Disease
    7. Implications of Gene Therapy in Bone Marrow Transplantation and Hematopoietic Cells
    8. Other Implications of Gene Therapy Cancer Treatment
    9. Practical Development of Gene Therapy Programs
    10. Poster Papers
    1. Virus-Directed Enzyme/Prodrug Therapy (VDEPT) Selectively Engineering Drug Sensitivity into Tumors (pages 104–114)

      BRIAN E. HUBER, CYNTHIA A. RICHARDS and ELIZABETH A. AUSTIN

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb21706.x

    2. Therapeutic Strategies Using c-erb B-2 Promoter-Controlled Drug Activation (pages 115–125)

      KAROL SIKORA, JONATHAN HARRIS, HELEN HURST and NICK LEMOINE

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb21707.x

    3. Gene Transfer of Drug Resistance Genes Implications for Cancer Therapy (pages 126–143)

      MICHAEL M. GOTTESMAN, URSULA A. GERMANN, IVAN AKSENTIJEVICH, YOSHIKAZU SUGIMOTO, CAROL O. CARDARELLI and IRA PASTAN

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb21708.x

  5. Immunomodulation through Gene Therapy: Implications for Neoplastic Disease

    1. Top of page
    2. The Beginnign: Strategy and Ethics
    3. Gene Transfer Technology I
    4. Gene Transfer Technology II
    5. Engineering Drug Sensitivity and Drug Resistance: Implications in Cancer Therapy
    6. Immunomodulation through Gene Therapy: Implications for Neoplastic Disease
    7. Implications of Gene Therapy in Bone Marrow Transplantation and Hematopoietic Cells
    8. Other Implications of Gene Therapy Cancer Treatment
    9. Practical Development of Gene Therapy Programs
    10. Poster Papers
    1. Direct Gene Transfer for the Understanding and Treatment of Human Disease (pages 144–153)

      GREGORY E. PLAUTZ, ELIZABETH G. NABEL, BERNARD FOX, ZHI-YONG YANG, MICHELE JAFFE, DAVID GORDON, ALFRED CHANG and GARY J. NABEL

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb21709.x

    2. Monoclonal Antibody Gene Transfer: Implications for Tumor-Specific Cell-Mediated Cytotoxicity (pages 154–166)

      F. JAMES PRIMUS, MARGARET D. FINCH, SCOTT A. WETZEL, ANN MARIA MASCI, JEFFREY SCHLOM and S. V. S. KASHMIRI

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb21710.x

    3. Retrovirus-Mediated Gene Transfer of the Human γ-IFN Gene: A Therapy for Cancer (pages 167–187)

      BRAD HOWARD, MICHELLE BURRASCANO, TAMMY McCALLISTER, KIM CHONG, RAMARAO GANGAVALLI, LIV SEVERINSSON, DOUGLAS J. JOLLY, TIMOTHY DARROW, CAROL VERVAERT, ZEINHAB ABDEL-WAHAB, HILLIARD F. SIEGLER and JACK R. BARBER

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb21711.x

    4. The Use of Gene-Modified Tumor-Infiltrating Lymphocytes for Cancer Therapy (pages 188–203)

      PATRICK HWU and STEVEN A. ROSENBERG

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb21712.x

  6. Implications of Gene Therapy in Bone Marrow Transplantation and Hematopoietic Cells

    1. Top of page
    2. The Beginnign: Strategy and Ethics
    3. Gene Transfer Technology I
    4. Gene Transfer Technology II
    5. Engineering Drug Sensitivity and Drug Resistance: Implications in Cancer Therapy
    6. Immunomodulation through Gene Therapy: Implications for Neoplastic Disease
    7. Implications of Gene Therapy in Bone Marrow Transplantation and Hematopoietic Cells
    8. Other Implications of Gene Therapy Cancer Treatment
    9. Practical Development of Gene Therapy Programs
    10. Poster Papers
    1. Gene Marking and Autologous Bone Marrow Transplantation (pages 204–215)

      MALCOLM K. BRENNER, DONNA R. RILL, ROBERT C. MOEN, ROBERT A. KRANCE, HELEN E. HESLOP, JOSEPH MIRRO JR., W. FRENCH ANDERSON and JAMES N. IHLE

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb21713.x

    2. Gene Transfer into Hematopoietic Cells: Implications for Cancer Therapy (pages 216–224)

      CYNTHIA E. DUNBAR, DAVID M. BODINE, BRIAN SORRENTINO, ROBERT DONAHUE, KEVIN McDONAGH, MICHELE COTTLER-FOX, JOYCE O'SHAUGHESSY, KENNETH COWAN, CHARLES CARTER, SANDRA DOREN, ALIZA CASSELL and ARTHUR W. NIENHUIS

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb21714.x

  7. Other Implications of Gene Therapy Cancer Treatment

    1. Top of page
    2. The Beginnign: Strategy and Ethics
    3. Gene Transfer Technology I
    4. Gene Transfer Technology II
    5. Engineering Drug Sensitivity and Drug Resistance: Implications in Cancer Therapy
    6. Immunomodulation through Gene Therapy: Implications for Neoplastic Disease
    7. Implications of Gene Therapy in Bone Marrow Transplantation and Hematopoietic Cells
    8. Other Implications of Gene Therapy Cancer Treatment
    9. Practical Development of Gene Therapy Programs
    10. Poster Papers
    1. Development of Antisense Therapeutics: Implications for Cancer Gene Therapy (pages 228–241)

      JOHN F. MILLIGAN, ROBERT J. JONES, BRIAN C. FROEHLER and MARK D. MATTEUCCI

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb21715.x

    2. H-ras Ribozyme-Mediated, Alteration of the Human Melanoma Phenotype (pages 242–256)

      YUKINORI OHTA, TAKESHI TONE, TOSHIYA SHITARA, TADAO FUNATO, LU JIAO, BRANDON I. KASHFIAN, EMMY YOSHIDA, MARK HORNG, PATRICIA TSAI, KAREN LAUTERBACH, MOHAMMED KASHANI-SABET, VIVA ANN FLORENES, OYSTEIN FODSTAD and KEVIN J. SCANLON

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb21716.x

    3. Gene Therapy and Endothelial Cell Targeting for Cancer (pages 257–264)

      ROBERT R. EVANS, THIERRY P. CALMELS, BRUCE R. PITT, MARGARET A. BROOKENS, CANDACE S. JOHNSON, RUTH A. MODZELEWSKI and JOHN S. LAZO

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb21717.x

  8. Practical Development of Gene Therapy Programs

    1. Top of page
    2. The Beginnign: Strategy and Ethics
    3. Gene Transfer Technology I
    4. Gene Transfer Technology II
    5. Engineering Drug Sensitivity and Drug Resistance: Implications in Cancer Therapy
    6. Immunomodulation through Gene Therapy: Implications for Neoplastic Disease
    7. Implications of Gene Therapy in Bone Marrow Transplantation and Hematopoietic Cells
    8. Other Implications of Gene Therapy Cancer Treatment
    9. Practical Development of Gene Therapy Programs
    10. Poster Papers
    1. Designing Clinical Trials of Somatic Gene Therapy (pages 283–293)

      FRED D. LEDLEY

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb21719.x

    2. Human Gene Therapy: Suggestions for Avoiding Liability (pages 294–306)

      JULIE GAGE PALMER

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb21720.x

    3. Transduction, Expression, and Secretion of Human Glucocerebrosidase by Murine Myoblasts (pages 307–320)

      VIJAYA BANSAL, PATRICIA MOWERY-RUSHTON, LORRIE LUCHT, JUAN LI, ALFRED BAHNSON, SIMON C. WATKINS and JOHN A. BARRANGER

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb21721.x

  9. Poster Papers

    1. Top of page
    2. The Beginnign: Strategy and Ethics
    3. Gene Transfer Technology I
    4. Gene Transfer Technology II
    5. Engineering Drug Sensitivity and Drug Resistance: Implications in Cancer Therapy
    6. Immunomodulation through Gene Therapy: Implications for Neoplastic Disease
    7. Implications of Gene Therapy in Bone Marrow Transplantation and Hematopoietic Cells
    8. Other Implications of Gene Therapy Cancer Treatment
    9. Practical Development of Gene Therapy Programs
    10. Poster Papers
    1. Double-Stranded Phosphorothioate, Oligonucleotide Modulation of Gene Expression (pages 321–323)

      K. C. ESS, J. J. HUTTON and B. J. ARONOW

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb21722.x

    2. Receptor-Mediated Gene Transfer into Hepatic Cells Using Asialoglycoprotein-Labeled Liposomes (pages 331–333)

      K. KOIKE, T. HARA, Y. ARAMAKI, S. TAKADA and S. TSUCHIYA

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb21725.x

    3. Mechanisms of Tumor Regression of TNF Gene-Transduced Meth-A Cells Transplanted in Mice (pages 334–335)

      YOSHIKAZU KOSHITA, YOSHINORI ITOH, SHIGEYUKI FUJII, HIROSHI NEDA, MINORU TAKAHASHI, NAOKI WATANABE, YUTAKA KOHGO and YOSHIRO NIITSU

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb21726.x

    4. Successful Transfection of Biotinylated β-Galactosidase Gene Conjugated with Transferrin into Leukemia Cells and Interleukin-2-Stimulated Lymphocytes via Transferrin Receptor (pages 336–337)

      H. NEDA, M. TAKAHASHI, Y. ITOH, Y. KOSHITA, T. MATSUYAMA, N. WATANABE, Y. KOHGO and Y. NIITSU

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb21727.x

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