Annals of the New York Academy of Sciences

Cover image for Annals of the New York Academy of Sciences

September 1994

Volume 737 Biology of 2-Macroglobulin, Its Receptor, and Related Proteins

Pages 1–517

  1. Session I. The α2M Receptor/LRP I

    1. Top of page
    2. Session I. The α2M Receptor/LRP I
    3. Session II. The α2M Receptor/LRP II
    4. Session III. α2M Structure and the Proteinase Reaction
    5. Session IV. Physiology and Pathology
    6. Session V. Poster Papers
    1. The α2-Macroglobulin Receptor/Low Density Lipoprotein Receptor-Related Protein and the Receptor-Associated Protein : An Overview (pages 1–13)

      SUZANNE E. WILLIAMS, MARIA Z. KOUNNAS, KELLEY M. ARGRAVES, W. SCOTT ARGRAVES and DUDLEY K. STRICKLAND

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb44297.x

    2. Functions of the LDL Receptor Gene Family (pages 14–19)

      JOACHIM HERZ and THOMAS E. WILLNOW

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb44298.x

    3. The Multiligand α2-Macroglobulin Receptor/Low Density Lipoprotein Receptor-Related Protein (α2MR/LRP) : Binding and Endocytosis of Fluid Phase and Membrane-Associated Ligands (pages 20–38)

      J. GLIEMANN, A. NYKJÆR, C. M. PETERSEN, K. E. JØRGENSEN, M. NIELSEN, P. A. ANDREASEN, E. I. CHRISTENSEN, A. LOOKENE, G. OLIVECRONA and S. K. MOESTRUP

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb44299.x

    4. Role of Heparan Sulfate Proteoglycans and the LDL Receptor-Related Protein in Remnant Lipoprotein Metabolism (pages 39–52)

      ROBERT W. MAHLEY, ZHONG-SHENG JI, WALTER J. BRECHT, R. DENNIS MIRANDA and DONGPING HE

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb44300.x

    5. The Role of α2M Receptor/LRP in Chylomicron Remnant Metabolism (pages 53–69)

      U. BEISIEGEL, A. KRAPP, W. WEBER and G. OLIVECRONA

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb44301.x

    6. LRP and the Receptor-Mediated Endocytosis of Plasminogen Activators (pages 70–87)

      ILKA WARSHAWSKY, GUOJUN BU and ALAN L. SCHWARTZ

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb44302.x

  2. Session II. The α2M Receptor/LRP II

    1. Top of page
    2. Session I. The α2M Receptor/LRP I
    3. Session II. The α2M Receptor/LRP II
    4. Session III. α2M Structure and the Proteinase Reaction
    5. Session IV. Physiology and Pathology
    6. Session V. Poster Papers
    1. gp330 and RAP: The Heymann Nephritis Antigenic Complex (pages 96–113)

      MARILYN G. FARQUHAR, DONTSCHO KERJASCHKI, MARITA LUNDSTROM and ROBERT A. ORLANDO

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb44304.x

    2. An Overview of the Structure and Function of Glycoprotein 330, a Receptor Related to the α2-Macroglobulin Receptor (pages 114–123)

      MARIA Z. KOUNNAS, STEINGRIMUR STEFANSSON, ELENA LOUKINOVA, KELLEY M. ARGRAVES, DUDLEY K. STRICKLAND and W. SCOTT ARGRAVES

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb44305.x

    3. Binding and Endocytosis of Proteins Mediated by Epithelial gp330 (pages 124–137)

      SØREN K. MOESTRUP, ERIK I. CHRISTENSEN, SØREN NIELSEN, KARL E. JØRGENSEN, SØREN E. BJØRN, HANS RØIGAARD and JØRGEN GLIEMANN

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb44306.x

    4. Selection of Pseudomonas Exotoxin—Resistant Cells with Altered Expression of α2MR/LRP (pages 138–144)

      DAVID J. FITZGERALD, CHARLOTTE M. FRYLING, ALEXEY ZDANOVSKY, CATHARINE B. SAELINGER, MARIA KOUNNAS, DUDLEY K. STRICKLAND and STEPHEN LEPPLA

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb44307.x

    5. The Chicken LDL Receptor—Related Protein/α2-Macroglobulin Receptor Family (pages 145–153)

      JOHANNES NIMPF and WOLFGANG J. SCHNEIDER

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb44308.x

    6. gp330: Receptor and Autoantigen (pages 154–162)

      GANG ZHENG, DAVID R. BACHINSKY, MAURO ABBATE, GIUSEPPE ANDRES, DENNIS BROWN, IVAN STAMENKOVIC, JOHN L. NILES and ROBERT T. McCLUSKEY

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb44309.x

  3. Session III. α2M Structure and the Proteinase Reaction

    1. Top of page
    2. Session I. The α2M Receptor/LRP I
    3. Session II. The α2M Receptor/LRP II
    4. Session III. α2M Structure and the Proteinase Reaction
    5. Session IV. Physiology and Pathology
    6. Session V. Poster Papers
    1. Molecular Analysis of the Human and Mouse α2M Family (pages 163–171)

      F. VAN LEUVEN, L. UMANS, K. LORENT, C. HILLIKER, L. SERNEELS, L. OVERBERGH, L. STAS and L. RAYMAKERS

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb44310.x

    2. α2M in the Horseshoe Crab A Structural and Functional Invertebrate Homologue (pages 188–201)

      PETER B. ARMSTRONG, LARS SOTTRUP-JENSEN, ATSUSHI IKAI, SUBITA SRIMAL and JAMES P. QUIGLEY

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb44312.x

    3. Electron Microscopic Visualization of the Human α2-Macroglobulin Receptor and Its Interaction with α2-Macroglobulin/Chymotrypsin Complex (pages 202–211)

      E. DELAIN, M. BARRAY, F. POCHON, J. GLIEMANN and S. K. MOESTRUP

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb44313.x

    4. Structure-Function Relationships of Human α2-Macroglobulin : Three-Dimensional Structures of Native α2-Macroglobulin and Its Methylamine and Chymotrypsin Derivatives (pages 212–228)

      JAMES K. STOOPS, JOHN P. SCHROETER, STEVEN J. KOLODZIEJ and DUDLEY K. STRICKLAND

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb44314.x

    5. Three-Dimensional Reconstruction of Human α2-Macroglobulin and Refinement of the Localization of Thiol Ester Bonds with Monomaleimido Nanogold (pages 229–244)

      NICOLAS BOISSET, PAWEL PENCZEK, FRANÇOIS POCHON, JOACHIM FRANK and JEAN LAMY

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb44315.x

    6. The Proteinase-Binding Reaction of α2M (pages 245–266)

      RICHARD D. FEINMAN

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb44316.x

  4. Session IV. Physiology and Pathology

    1. Top of page
    2. Session I. The α2M Receptor/LRP I
    3. Session II. The α2M Receptor/LRP II
    4. Session III. α2M Structure and the Proteinase Reaction
    5. Session IV. Physiology and Pathology
    6. Session V. Poster Papers
    1. α2-Macroglobulin and the α2-Macroglobulin Receptor/LRP A Growth Regulatory Axis (pages 273–290)

      STEVEN L. GONIAS, JONATHAN LaMARRE, KENDALL P. CROOKSTON, DONNA J. WEBB, BENI B. WOLF, M. BEATRIZ S. LOPES, HAROLD L. MOSES and M. ANTHONY HAYES

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb44318.x

    2. α2-Macroglobulin: A Sensor for Proteolysis (pages 291–307)

      CHARLEEN T. CHU, GAYLE C. HOWARD, UMA K. MISRA and SALVATORE V. PIZZO

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb44319.x

    3. Regulation of α2-Macroglobulin Gene Expression by Interleukin-6 (pages 308–323)

      FRIEDEMANN HORN, URSULA MARIA WEGENKA, CLAUDIA LÜTTICKEN, JUPING YUAN, ELKE ROEB, WILLEM BOERS, JAN BUSCHMANN and PETER CLAUS HEINRICH

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb44320.x

    4. Modulation of Immune Cell Activities by α2-Macroglobulin : A Proposed Physiological Role Based on Activation Kinetics and Model Vaccine Studies (pages 339–346)

      ATSUSHI IKAI, NAOKO KOYANO, SHINOBU MITSUDA and NOZOMU SHIBUYA

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb44322.x

    5. Significance of the Regulation of Plasma Kallikrein by α2M (pages 347–367)

      ROBERT W. COLMAN

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb44323.x

    6. α2-Macroglobulin/Transforming Growth Factor-β1 Interactions : Modulation by Heparin-like Molecules and Effects on Vascular Smooth Muscle Cellsa (pages 368–382)

      TIMOTHY A. McCAFFREY, DOMENICK J. FALCONE, WOLFGANG BORTH and BABETTE B. WEKSLER

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb44324.x

    7. α2-Macroglobulin and the Control of Adrenocortical Steroidogenic Function (pages 399–408)

      CATHERINE SAVONA, ADRIEN NEGOESCU, FRANÇOISE LABAT-MOLEUR, MICHELLE KERAMIDAS, DE LI SHI, EDMOND M. CHAMBAZ and JEAN-JACQUES FEIGE

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb44326.x

    8. α2-Macroglobulin in the Regulation of Pericellular Plasminogen Activation of Human Tumor Cells (pages 409–418)

      ANTTI VAHERI, HANNELE TAPIOVAARA, HELI MYÖHÄNEN and JOZEF BIZIK

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb44327.x

  5. Session V. Poster Papers

    1. Top of page
    2. Session I. The α2M Receptor/LRP I
    3. Session II. The α2M Receptor/LRP II
    4. Session III. α2M Structure and the Proteinase Reaction
    5. Session IV. Physiology and Pathology
    6. Session V. Poster Papers
    1. Kinetics of Proteinase Trapping by α2M (pages 419–420)

      HIDEO ARAKAWA, TAKUJI URISAKA, MASARU SHIMIZU and ATSUSHI IKAI

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb44328.x

    2. Feedback Mechanisms between α2M and TGFβ1 Reduce Extracellular Matrix Synthesis of Liver Fat-Storing Cells (pages 421–424)

      M. G. BACHEM, G. SCHÜFTAN, P. SCHIRRMACHER and A. M. GRESSNER

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb44329.x

    3. Determination of Total and Transformed α2-Macroglobulin by a Monoclonal Antibody Immunosorption Assay in Patients with Different Diseases (pages 425–427)

      G. BIRKENMEIER, H. L. SCHUKE, S. BRIEST and G. KOPPERSCHLÄGER

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb44330.x

    4. Uptake of Methylamine-Activated α2-Macroglobulin by Rat Liver (pages 428–430)

      W. BOERS, C. LINTHORST, M. C. M. VAN DIJK and T. J. C. VAN BERKEL

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb44331.x

    5. The Cleavage of the Bait Region of α2-Macroglobulin by Human Immunodeficiency Virus Proteinases and by Astacin (pages 431–433)

      UTE-CHRISTIANE MEIER, JOACHIM BOETZEL, JOSEF KELLERMANN, KARLHEINZ MANN, ANDREAS BILLICH, WALTER STÖCKER and HANS J. SCHRAMM

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb44332.x

    6. The Carboxy-Terminal Domain of Lipoprotein Lipase Induces Cellular Catabolism of Normal Very Low Density Lipoproteins via the Low Density Lipoprotein Receptor—Related Protein/α2-Macroglobulin Receptor (pages 434–438)

      DAVID A. CHAPPELL, ITURO INOUE, GLENNA L. FRY, MARC W. PLADET, PER-HENRIK IVERIUS, JEAN-MARC LALOUEL and DUDLEY K. STRICKLAND

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb44333.x

    7. Human α2-Macroglobulin as a Cytokine-Binding Plasma Protein : A Study with rh-Interleukin-1β and rh-Interleukin-6 (pages 439–443)

      L. G. Legrès, F. POCHON, M. BARRAY, P. C. HEINRICH and E. DELAIN

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb44334.x

    8. Crystallization of Proteins of the α2-Macroglobulin Superfamily (pages 444–446)

      GREGERS R. ANDERSEN, TRINE KOCH, ANDERS H. SO̊ENSEN, SO̊EN THIRUP, JENS NYBORG, KLAVS DOLMER, LINDA JACOBSEN and LARS SOTTRUP-JENSEN

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb44335.x

    9. The Importance of the α2MR/LRP for Human Genetics : Investigations of the Receptor Expression in Different Human Blood Cells (pages 447–450)

      CHRISTIANE GLÄSER, KATRIN HANDSCHUG, SABINE LUDVIK, UTE SCHELL, ANDREAS HEHR, ANDREAS KÜCHENHOFF and HORST ROBENEK

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb44336.x

    10. Disulfide Bond Formation by Methanethiolation of the Thiol Ester Sulfhydryl Group of α2M (pages 451–452)

      POUL ERIK H. JENSEN, VITHALDAS P. SHANBHAG and TORGNY STIGBRAND

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb44337.x

    11. α2-Macroglobulin in Experimental and Human Chagas' Disease (pages 453–455)

      T. C. ARAÚJO-JORGE, M. R. M. P. LUZ, C. M. L. M. COUTINHO, N. MEDRANO, M. N. C. SOEIRO, M. N. L. MEIRELLES, L. ISAAC and F. VAN LEUVEN

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb44338.x

    12. Binding of Nerve Growth Factor to Different Forms of α2-Macroglobulin (pages 456–459)

      KLAUS KECK, ZANE ORINSKA and MICHAELA WALDSCHÜTZ

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb44339.x

    13. β-VLDL : A Naturally Occurring Ligand for LRP with Physiological Importance (pages 465–467)

      A. KÜCHENHOFF, B. HARRACH and H. ROBENEK

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb44341.x

    14. α2-Macroglobulin: A Ferritin-Binding Protein (pages 468–471)

      WILLIAM H. MASSOVER

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb44342.x

    15. The Primary Structure of Ovomacroglobulin (pages 476–479)

      KÅRE LEHMANN NIELSEN, LARS SOTTRUP-JENSEN, HIDEAKI NAGASE and MICHAEL ETZERODT

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb44344.x

    16. Recombinant α2M Receptor Binding Domain Binds to the α2M Receptor with High Affinity (pages 480–482)

      T. L. HOLTET, K. L. NIELSEN, M. ETZERODT, S. K. MOESTRUP, J. GLIEMANN, L. SOTTRUP-JENSEN and H. C. THØGERSEN

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb44345.x

    17. Receptors for α2-Macroglobulin Are Present on Human Dermal Fibroblasts, but Not on Human Keratinocytes (pages 490–492)

      STEVEN R. FELDMAN, TORU SEO and RICHARD W. ST. CLAIR

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb44348.x

    18. Cloning and Expression of the 15-kDa C-Terminal Peptide from the Human α2-Macroglobulin as a Fusion-Protein Product in a Prokaryotic Cell Line (pages 493–495)

      AMAN MOTTAQUI-TABAR, POUL ERIK JENSEN, TORGNY STIGBRAND, BENGT-HERALD JONSSON and VITHALDAS P. SHANBHAG

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb44349.x

    19. Characterization of the Genes Coding for the Murinoglobulins and Expression in Vivo (pages 496–497)

      L. OVERBERGH, K. LORENT, C. HILLIKER and F. VAN LEUVEN

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb44350.x

    20. Expression of Mouse α2M and Its Receptor in Vivo (pages 498–499)

      K. LORENT, L. OVERBERGH and F. VAN LEUVEN

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb44351.x

    21. Structure and Targeting in ES Cells of the Gene Coding for Mouse α2-Macroglobulin (pages 500–501)

      L. UMANS, L. SERNEELS, C. HILLIKER and F. VAN LEUVEN

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb44352.x

    22. Structure of the Human α2M Receptor Gene (pages 502–503)

      F. VAN LEUVEN, L. STAS, L. RAYMAKERS and C. HILLIKER

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb44353.x

    23. The Human and Mouse Genes Coding for the α2MR-Associated Protein (pages 504–505)

      F. VAN LEUVEN, L. SERNEELS, L. RAYMAKERS, C. HILLIKER and L. UMANS

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb44354.x

    24. Temperature-Dependent Biosynthesis of Thiol Esters in Baculovirus Recombinant α2M and PZP (pages 506–509)

      L. VAN ROMPAEY and P. MARYNEN

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb44355.x

    25. Binding of Lipoprotein Lipase to α2-Macroglobulin (pages 510–513)

      E. VILELLA, J. JOVEN, G. OLIVECRONA, T. STIGBRAND and P. E. JENSEN

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1994.tb44356.x

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