Annals of the New York Academy of Sciences

Cover image for Annals of the New York Academy of Sciences

August 1995

Volume 760 Osteopontin: Role in Cell Signalling and Adhesion

Pages xi–xi, 1–382

    1. Preface (page xi)

      David T. Denhardt, William T. Butler, Ann F. Chambers and Donald R. Senger

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb44613.x

    2. Osteopontin Overview (pages 1–5)

      GIDEON A. RODAN

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb44614.x

  1. Part I. Physical Properties of Osteopontin

    1. Top of page
    2. Part I. Physical Properties of Osteopontin
    3. Part II. Osteopontin Gene Structure and Regulation
    4. Part III. Control of Osteopontin Expression in Normal and Abnormal Cells
    5. Part IV. Signalling Properties of Osteopontin
    6. Part V. Cell Adhesion Properties of Osteopontin
    7. Part VI. Role of Osteopontin in Bone Metabolism
    8. Part VII. Function of Osteopontin in the Kidney and Inner Ear
    9. Poster Papers
    1. Structural and Functional Domains of Osteopontin (pages 6–11)

      WILLIAM T. BUTLER

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb44615.x

    2. Conformational Analyses on Soluble and Surface Bound Osteopontin (pages 12–23)

      JEFFREY P. GORSKI, EDWARD KREMER, JAVIER RUIZ-PEREZ, GARY E. WISE and ANTONIO ARTIGUES

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb44616.x

    3. Effects of Okadaic Acid on Calcitriol-and Phorbol Ester-Induced Expression and Phosphorylation of Osteopontin in Mouse JB6 Epidermal Cells (pages 24–34)

      PI-LING CHANG, WEI-CHUNG YANG and CHARLES W. PRINCE

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb44617.x

    4. Gene Expression and Phosphorylation of Mouse Osteopontin (pages 35–43)

      RAUL A. SAAVEDRA, SEAN K. KIMBRO, DORIS N. STERN, JAMIE SCHNUER, SAMY ASHKAR, MELVIN J. GLIMCHER and CECILIA I. LJUBETIC

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb44618.x

  2. Part II. Osteopontin Gene Structure and Regulation

    1. Top of page
    2. Part I. Physical Properties of Osteopontin
    3. Part II. Osteopontin Gene Structure and Regulation
    4. Part III. Control of Osteopontin Expression in Normal and Abnormal Cells
    5. Part IV. Signalling Properties of Osteopontin
    6. Part V. Cell Adhesion Properties of Osteopontin
    7. Part VI. Role of Osteopontin in Bone Metabolism
    8. Part VII. Function of Osteopontin in the Kidney and Inner Ear
    9. Poster Papers
    1. Structure of the Osteopontin Gene and Its Promoter (pages 44–58)

      SHUNSUKE YAMAMOTO, NAOKI HIJIYA, MIHOKO SETOGUCHI, KEIKO MATSUURA, TETSUYA ISHIDA, YASUNORI HIGUCHI and SHIN' ICHIRO AKIZUKI

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb44619.x

    2. Characterization of the Rat Osteopontin Gene : Evidence for Two Vitamin D Response Elements (pages 59–66)

      AMY L. RIDALL, ELIZABETH L. DAANE, DOUGLAS P. DICKINSON and WILLIAM T. BUTLER

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb44620.x

    3. Regulation of Avian Osteopontin Pre-and Posttranscriptional Expression in Skeletal Tissues (pages 67–82)

      L. C. GERSTENFELD, T. UPOROVA, S. ASHKAR, E. SALIH, Y. GOTOH, M. D. McKEE, A. NANCI and M. J. GLIMCHER

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb44621.x

  3. Part III. Control of Osteopontin Expression in Normal and Abnormal Cells

    1. Top of page
    2. Part I. Physical Properties of Osteopontin
    3. Part II. Osteopontin Gene Structure and Regulation
    4. Part III. Control of Osteopontin Expression in Normal and Abnormal Cells
    5. Part IV. Signalling Properties of Osteopontin
    6. Part V. Cell Adhesion Properties of Osteopontin
    7. Part VI. Role of Osteopontin in Bone Metabolism
    8. Part VII. Function of Osteopontin in the Kidney and Inner Ear
    9. Poster Papers
    1. Osteopontin at the Tumor/Host Interface : Functional Regulation by Thrombin-Cleavage and Consequences for Cell Adhesion (pages 83–100)

      Donald R. Senger, Lawrence F. Brown, Carole A. Perruzzi, Ageliki Papadopoulos-Sergiou and Livingston Van De Water

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb44622.x

    2. Regulation and Function of Osteopontin in Ras-Transformed Cells (pages 101–108)

      ANN F. CHAMBERS

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb44623.x

    3. Osteopontin Expression in Cardiovascular Diseases (pages 109–126)

      CECILIA M. GIACHELLI, LUCY LIAW, CHARLES E. MURRY, STEPHEN M. SCHWARTZ and MANUELA ALMEIDA

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb44624.x

  4. Part IV. Signalling Properties of Osteopontin

    1. Top of page
    2. Part I. Physical Properties of Osteopontin
    3. Part II. Osteopontin Gene Structure and Regulation
    4. Part III. Control of Osteopontin Expression in Normal and Abnormal Cells
    5. Part IV. Signalling Properties of Osteopontin
    6. Part V. Cell Adhesion Properties of Osteopontin
    7. Part VI. Role of Osteopontin in Bone Metabolism
    8. Part VII. Function of Osteopontin in the Kidney and Inner Ear
    9. Poster Papers
    1. Osteopontin-Induced Modifications of Cellular Functions (pages 127–142)

      DAVID T. DENHARDT, CECILIA A. LOPEZ, ELLEN E. ROLLO, SHIAW-MIN HWANG, XIAO-RONG AN and SUSAN E. WALTHER

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb44625.x

    2. The Role of Eta-1/Osteopontin in the Pathogenesis of Immunological Disorders (pages 143–150)

      HARVEY CANTOR

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb44626.x

    3. Engagement of the Osteoclast Integrin αvβ3 by Osteopontin Stimulates Phosphatidylinositol 3-Hydroxyl Kinase Activityb (pages 151–165)

      KEITH A. HRUSKA, FELICE ROLNICK, MARGARET HUSKEY, ULISES ALVAREZ and DAVID CHERESH

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb44627.x

  5. Part V. Cell Adhesion Properties of Osteopontin

    1. Top of page
    2. Part I. Physical Properties of Osteopontin
    3. Part II. Osteopontin Gene Structure and Regulation
    4. Part III. Control of Osteopontin Expression in Normal and Abnormal Cells
    5. Part IV. Signalling Properties of Osteopontin
    6. Part V. Cell Adhesion Properties of Osteopontin
    7. Part VI. Role of Osteopontin in Bone Metabolism
    8. Part VII. Function of Osteopontin in the Kidney and Inner Ear
    9. Poster Papers
    1. Localization and Expression of Osteopontin in Mineralized and Nonmineralized Tissues of the Periodontium (pages 166–176)

      R. L. MacNEIL, J. BERRY, J. D'ERRICO, C. STRAYHORN and M. J. SOMERMAN

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb44628.x

    2. Interaction of Osteopontin with Osteoclast Integrins (pages 190–200)

      MICHAEL A. HORTON, M. ANDREW NESBIT and MIEP H. HELFRICH

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb44630.x

    3. Interaction of Osteopontin with Fibronectin and Other Extracellular Matrix Molecules (pages 201–212)

      BARID B. MUKHERJEE, MOHAMED NEMIR, SIMONE BENINATI, ELEONORA CORDELLA-MIELE, KRISHNA SINGH, ISAAC CHACKALAPARAMPIL, VIJAYALAKSHMI SHANMUGAM, MICHAEL W. DeVOUGE and ANIL B. MUKHERJEE

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb44631.x

  6. Part VI. Role of Osteopontin in Bone Metabolism

    1. Top of page
    2. Part I. Physical Properties of Osteopontin
    3. Part II. Osteopontin Gene Structure and Regulation
    4. Part III. Control of Osteopontin Expression in Normal and Abnormal Cells
    5. Part IV. Signalling Properties of Osteopontin
    6. Part V. Cell Adhesion Properties of Osteopontin
    7. Part VI. Role of Osteopontin in Bone Metabolism
    8. Part VII. Function of Osteopontin in the Kidney and Inner Ear
    9. Poster Papers
    1. Roles of Osteopontin in Bone Remodeling (pages 213–222)

      DICK HEINEGÅRD, GÖRAN ANDERSSON and FINN P. REINHOLT

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb44632.x

    2. Regulation of Osteopontin Expression in Osteoblasts (pages 223–241)

      JARO SODEK, JINKUN CHEN, TOSHIHIKO NAGATA, SHOHEI KASUGAI, REYNALDO TODESCAN JR., IVAN W. S. LI and RICHARD H. KIM

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb44633.x

    3. Regulation of Osteopontin Gene Expression in Osteoblasts (pages 242–248)

      MASAKI NODA and DAVID T. DENHARDT

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb44634.x

    4. Osteopontin and Related Phosphorylated Sialoproteins: Effects on Mineralization (pages 249–256)

      ADELE L. BOSKEY

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb44635.x

  7. Part VII. Function of Osteopontin in the Kidney and Inner Ear

    1. Top of page
    2. Part I. Physical Properties of Osteopontin
    3. Part II. Osteopontin Gene Structure and Regulation
    4. Part III. Control of Osteopontin Expression in Normal and Abnormal Cells
    5. Part IV. Signalling Properties of Osteopontin
    6. Part V. Cell Adhesion Properties of Osteopontin
    7. Part VI. Role of Osteopontin in Bone Metabolism
    8. Part VII. Function of Osteopontin in the Kidney and Inner Ear
    9. Poster Papers
    1. Osteopontin in Urinary Stone Formation (pages 257–265)

      JOHN R. HOYER, LASZLO OTVOS JR. and LASZLO URGE

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb44636.x

    2. Osteopontin Production by Cultured Kidney Cells (pages 266–278)

      ELAINE M. WORCESTER, JACK G. KLEINMAN and ANN M. BESHENSKY

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb44637.x

    3. Expression of Osteopontin in the Inner Ear (pages 279–295)

      ROBIN L. DAVIS, CECILIA A. LOPEZ and KEWA MOU

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb44638.x

  8. Poster Papers

    1. Top of page
    2. Part I. Physical Properties of Osteopontin
    3. Part II. Osteopontin Gene Structure and Regulation
    4. Part III. Control of Osteopontin Expression in Normal and Abnormal Cells
    5. Part IV. Signalling Properties of Osteopontin
    6. Part V. Cell Adhesion Properties of Osteopontin
    7. Part VI. Role of Osteopontin in Bone Metabolism
    8. Part VII. Function of Osteopontin in the Kidney and Inner Ear
    9. Poster Papers
    1. Phosphorylation of Osteopontin by Golgi Kinases (pages 296–298)

      S. ASHKAR, J. L. SCHAFFER, E. SALIH, L. C. GERSTENFELD and M. J. GLIMCHER

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb44639.x

    2. Expression of Antisense Osteopontin RNA in Metastatic Mouse Fibroblasts Is Associated with Reduced Malignancy (pages 299–301)

      E. I. BEHREND, A. M. CRAIG, S. M. WILSON, D. T. DENHARDT and A. F. CHAMBERS

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb44640.x

    3. HL-60 Cell Differentiation and Osteopontin Expression (pages 302–304)

      JANICE E. BERRY, MARTHA J. SOMERMAN, ZHILA KHALKHALI-ELLIS, PHIL OSDOBY and ROBERT U. SIMPSON

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb44641.x

    4. The Inhibitory Activity of Osteopontin on Hydroxyapatite Formation In Vitro (pages 305–308)

      HARVEY A. GOLDBERG and GRAEME K. HUNTER

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb44642.x

    5. A Monoclonal Antibody against Osteopontin Inhibits RGD-Mediated Cell Adhesion to Osteopontin (pages 309–311)

      D. S. BAUTISTA, J-W. XUAN, C. HOTA, A. F. CHAMBERS and J. F. HARRIS

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb44643.x

    6. Characterization of the Interaction between Integrins and Recombinant Human Osteopontin (pages 312–314)

      DANA D. HU, JOHN R. HOYER and JEFFREY W. SMITH

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb44644.x

    7. Osteopontin: a Ligand for the αvβ3 Integrin of the Osteoclast Clear Zone in Osteopetrotic (ia/ia) Rats (pages 315–318)

      K. HULTENBY, F. P. REINHOLT, D. HEINEGÅRD, G. ANDERSSON and S. C. MARKS JR.

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb44645.x

    8. The Puerap Motif in the Promoter of the Mouse Osteopontin Gene (pages 319–320)

      KEVIN S. KIMBRO and RAUL A. SAAVEDRA

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb44646.x

    9. Upregulation of Osteopontin Expression by Ischemia in Rat Kidney (pages 321–323)

      J. G. KLEINMAN, E. M. WORCESTER, A. M. BESHENSKY, A. M. SHERIDAN, J. V. BONVENTRE and D. BROWN

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb44647.x

    10. Activation of a Signal Transduction Pathway by Osteopontin (pages 324–326)

      CECILIA A. LOPEZ, ROBIN L. DAVIS, KEWA MOU and DAVID T. DENHARDT

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb44648.x

    11. The Mutagenesis of the RGD Sequence of Recombinant Osteopontin Causes It to Lose Its Cell Adhesion Ability (pages 327–331)

      ROSSOLYN J. McFARLAND, SONYA GARZA, WILLIAM T. BUTLER and MAGNUS HÖÖK

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb44649.x

    12. Divergent Expressions of Two Cell Adhesion Molecules at the Leading Edge of a Migrating Cell Sheet (pages 332–333)

      R. N. MASCARDO, J. KSIAZEK and R. W. BARTON

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb44650.x

    13. Expression of Osteopontin in a Macrophage Cell Line and in Transgenic Mice with Pulmonary Fibrosis Resulting from the Lung Expression of a Tumor Necrosis Factor-α Transgene (pages 334–341)

      YOSHITAKA MIYAZAKI, TAKAYOSHI TASHIRO, YASUNORI HIGUCHI, MIHOKO SETOGUCHI, SHUNSUKE YAMAMOTO, HIROYUKI NAGAI, MASARU NASU and PIERRE VASSALLI

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb44651.x

    14. Osteopontin Expression in Clonal Dental Pulp Cells (pages 342–345)

      TOSHIHIKO NAGATA, MIKA YOKOTA, SEIJI NISHIKAWA, HIROSHI ISHIDA and YOICHI WAKANO

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb44652.x

    15. Regulated Expression of Osteopontin in Human Trophoblasts (pages 346–349)

      AKINYINKA OMIGBODUN, ERIC DAITER, DENISE WALINSKY, LARRY FISHER, MARIAN YOUNG, JOHN HOYER and CHRISTOS COUTIFARIS

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb44653.x

    16. Osteopontin Gene Expression in Avian Tibial Dyschondroplasia (pages 350–353)

      V. KNOPOV, R. M. LEACH, T. BARAK-SHALOM, S. HURWITZ and M. PINES

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb44654.x

    17. Osteopontin mRNA Expression in a Chemically-Induced Model of Atherogenesis (pages 354–356)

      ALAN R. PARRISH and KENNETH S. RAMOS

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb44655.x

    18. Identification of the In Vivo Phosphorylated Sites of Secreted Osteopontin from Cultured Chicken Osteoblasts (pages 357–360)

      ERDJAN SALIH, SAMY ASHKAR, LOUIS C. GERSTENFELD and MELVIN J. GLIMCHER

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb44656.x

    19. Identification of Osteopontin mRNA and Protein in Rat Epididymis and of Protein on Epididymal Sperm (pages 361–362)

      JON E. SIITERI and DAVID W. HAMILTON

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb44657.x

    20. Phosphorylation, Glycosylation, and Transglutaminase Sites in Bovine Osteopontin (pages 363–366)

      ESBEN S. SØRENSEN and TORBEN E. PETERSEN

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb44658.x

    21. Localization of Osteopontin during Mouse Development (pages 367–370)

      D. N. STERN, M. J. GLIMCHER and R. A. SAAVEDRA

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb44659.x

    22. Functional Analysis of the Osteopontin Molecule (pages 371–374)

      YOHKO KATAGIRI, KIYOSHI MORI, TOYOMICHI HARA, KUMIKO TANAKA, MASAAKI MURAKAMI and TOSHIMITSU UEDE

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb44660.x

    23. Osteopontin Inhibits Nucleation of Calcium Oxalate Crystals (pages 375–377)

      ELAINE M. WORCESTER and ANN M. BESHENSKY

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb44661.x

    24. Effect of Recombinant Osteopontin on Adhesion and Migration of P388D1 Cells (pages 378–380)

      SHUNSUKE YAMAMOTO, KAEI NASU, TETSUYA ISHIDA, MIHOKO SETOGUCHI, YASUNORI HIGUCHI, NAOKI HIJIYA and SHIN' ICHIRO AKIZUKI

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb44662.x

    25. High Expression of Osteopontin mRNA in Human Macrophages but Not Human Vascular Smooth Muscle Cells in Culture (pages 381–382)

      C. M. NEWMAN, B. C. BRUUN, P. K. MISTRY, P. L. WEISSBERG and C. M. SHANAHAN

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb44663.x

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