Annals of the New York Academy of Sciences

Cover image for Annals of the New York Academy of Sciences

December 1995

Volume 774 Dehydroepiandrosterone (DHEA) and Aging

Pages ix–xiv, 1–341

    1. INTRODUCTION : DHEA: A Coming of Age (pages ix–xi)

      JOHN E. NESTLER

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb17366.x

    2. Current Challenges for DHEA Research (pages xiii–xiv)

      PETER J. HORNSBY

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb17367.x

  1. Poster Papers

    1. Top of page
    2. Poster Papers
    3. Part I. Age-Dependent Changes in Circulating DHEA and DHEA Biosynthesis
    4. Part II. DHEA and Neurologic Function
    5. Part III. Physiology of DHEA Metabolism
    6. Part IV. Biochemical Modes of Action for DHEA and Selected Metabolic Actions
    7. Part V. DHEA, Immunology, and Aging
    8. Part VI. DHEA and the Atherosclerosis of Aging
    9. Poster Papers
    1. An Abbreviated Account of Some Aspects of the Biochemistry of DHEA, 1934–1995 (pages 1–15)

      SEYMOUR LIEBERMAN

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb17368.x

  2. Part I. Age-Dependent Changes in Circulating DHEA and DHEA Biosynthesis

    1. Top of page
    2. Poster Papers
    3. Part I. Age-Dependent Changes in Circulating DHEA and DHEA Biosynthesis
    4. Part II. DHEA and Neurologic Function
    5. Part III. Physiology of DHEA Metabolism
    6. Part IV. Biochemical Modes of Action for DHEA and Selected Metabolic Actions
    7. Part V. DHEA, Immunology, and Aging
    8. Part VI. DHEA and the Atherosclerosis of Aging
    9. Poster Papers
    1. DHEA and Peripheral Androgen and Estrogen Formation: Intracrinology (pages 16–28)

      FERNAND LABRIE, ALAIN BÉLANGER, JACQUES SIMARD, VAN LUU-THE and CLAUDE LABRIE

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb17369.x

    2. Biosynthesis of DHEAS by the Human Adrenal Cortex and Its Age-Related Decline (pages 29–46)

      PETER J. HORNSBY

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb17370.x

    3. Adrenal Androgen Biosynthesis with Special Attention to P450c17 (pages 47–58)

      J. IAN MASON, IAN M. BIRD and WILLIAM E. RAINEY

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb17371.x

    4. Human Dehydroepiandrosterone Sulfotransferase : Purification, Molecular Cloning, and Characterization (pages 59–72)

      CHARLES N. FALANY, KATHLEEN A. COMER, THOMAS P. DOOLEY and HANSRUEDI GLATT

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb17372.x

    5. Regulation of Human Dehydroepiandrosterone Metabolism by Insulin (pages 73–81)

      JOHN E. NESTLER

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb17373.x

  3. Part II. DHEA and Neurologic Function

    1. Top of page
    2. Poster Papers
    3. Part I. Age-Dependent Changes in Circulating DHEA and DHEA Biosynthesis
    4. Part II. DHEA and Neurologic Function
    5. Part III. Physiology of DHEA Metabolism
    6. Part IV. Biochemical Modes of Action for DHEA and Selected Metabolic Actions
    7. Part V. DHEA, Immunology, and Aging
    8. Part VI. DHEA and the Atherosclerosis of Aging
    9. Poster Papers
    1. Dehydroepiandrosterone (DHEA) Is a Neuroactive Neurosteroid (pages 82–110)

      PAUL ROBEL and ETIENNE-EMILE BAULIEU

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb17374.x

  4. Part III. Physiology of DHEA Metabolism

    1. Top of page
    2. Poster Papers
    3. Part I. Age-Dependent Changes in Circulating DHEA and DHEA Biosynthesis
    4. Part II. DHEA and Neurologic Function
    5. Part III. Physiology of DHEA Metabolism
    6. Part IV. Biochemical Modes of Action for DHEA and Selected Metabolic Actions
    7. Part V. DHEA, Immunology, and Aging
    8. Part VI. DHEA and the Atherosclerosis of Aging
    9. Poster Papers
    1. Dehydroepiandrosterone Sulfate and Aging (pages 121–127)

      A. VERMEULEN

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb17376.x

    2. Replacement of DHEA in Aging Men and Women : Potential Remedial Effects (pages 128–142)

      S. S. C. YEN, A. J. MORALES and O. KHORRAM

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb17377.x

    3. Metabolism of Dehydroepiandrosterone (pages 143–148)

      CHRISTOPHER LONGCOPE

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb17378.x

    4. Pleotropic Effects of Dietary DHEA (pages 149–170)

      LEON MILEWICH, FERNANDO CATALINA and MICHAEL BENNETT

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb17379.x

  5. Part IV. Biochemical Modes of Action for DHEA and Selected Metabolic Actions

    1. Top of page
    2. Poster Papers
    3. Part I. Age-Dependent Changes in Circulating DHEA and DHEA Biosynthesis
    4. Part II. DHEA and Neurologic Function
    5. Part III. Physiology of DHEA Metabolism
    6. Part IV. Biochemical Modes of Action for DHEA and Selected Metabolic Actions
    7. Part V. DHEA, Immunology, and Aging
    8. Part VI. DHEA and the Atherosclerosis of Aging
    9. Poster Papers
    1. Induction of Thermogenic Enzymes by DHEA and Its Metabolites (pages 171–179)

      HENRY LARDY, NANCY KNEER, MONICA BELLEI and VALENTINA BOBYLEVA

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb17380.x

    2. Mechanism of Cancer Preventive Action of DHEA : Role of Glucose-6-Phosphate Dehydrogenase (pages 180–186)

      ARTHUR G. SCHWARTZ and LAURA L. PASHKO

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb17381.x

    3. Regulation of Cytochromes P450 by DHEA and Its Anticarcinogenic Action (pages 187–199)

      R. A. PROUGH, X.-D. LEI, G.-H. XIAO, H.-Q. WU, T. E. GEOGHEGAN and S. J. WEBB

      Article first published online: 17 DEC 2006 | DOI: 10.1111/rp10.1196-annals.1402.auindex_1

  6. Part V. DHEA, Immunology, and Aging

    1. Top of page
    2. Poster Papers
    3. Part I. Age-Dependent Changes in Circulating DHEA and DHEA Biosynthesis
    4. Part II. DHEA and Neurologic Function
    5. Part III. Physiology of DHEA Metabolism
    6. Part IV. Biochemical Modes of Action for DHEA and Selected Metabolic Actions
    7. Part V. DHEA, Immunology, and Aging
    8. Part VI. DHEA and the Atherosclerosis of Aging
    9. Poster Papers
    1. Does DHEAS Restore Immune Competence in Aged Animals through Its Capacity to Function as a Natural Modulator of Peroxisome Activities? (pages 200–216)

      NINA F. L. SPENCER, MATTHEW E. POYNTER, JON D. HENNEBOLD, HONG-HUA MU and RAYMOND A. DAYNES

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb17382.x-i1

    2. Adaptation to Chronic Stress in Military Trainees : Adrenal Androgens, Testosterone, Glucocorticoids, IGF-1, and Immune Function (pages 217–231)

      EDWARD BERNTON, DAVID HOOVER, RICHARD GALLOWAY and KATHRYN POPP

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb17383.x-i1

    3. DHEAS as an Effective Vaccine Adjuvant in Elderly Humans : Proof-of-Principle Studies (pages 232–248)

      BARBARA ARANEO, TAD DOWELL, MARION L. WOODS, RAYMOND DAYNES, MICHAEL JUDD and THOMAS EVANS

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb17384.x-i1

    4. Relationship between Humoral Immunoaugmenting Properties of DHEAS and IgD-Receptor Expression in Young and Aged Mice (pages 249–258)

      CHRISTINA D. SWENSON, SUSAN R. S. GOTTESMAN, DONALD V. BELSITO, KAREN M. SAMANICH, JOANNE EDINGTON and G. JEANETTE THORBECKE

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb17385.x-i1

  7. Part VI. DHEA and the Atherosclerosis of Aging

    1. Top of page
    2. Poster Papers
    3. Part I. Age-Dependent Changes in Circulating DHEA and DHEA Biosynthesis
    4. Part II. DHEA and Neurologic Function
    5. Part III. Physiology of DHEA Metabolism
    6. Part IV. Biochemical Modes of Action for DHEA and Selected Metabolic Actions
    7. Part V. DHEA, Immunology, and Aging
    8. Part VI. DHEA and the Atherosclerosis of Aging
    9. Poster Papers
    1. The Epidemiology of DHEAS and Cardiovascular Disease (pages 259–270)

      ELIZABETH BARRETT-CONNOR and DEBORAH GOODMAN-GRUEN

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb17386.x-i1

    2. Dehydroepiandrosterone and Coronary Atherosclerosis (pages 271–280)

      DAVID M. HERRINGTON

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb17387.x-i1

    3. Dehydroepiandrosterone Inhibits Human Platelet Aggregation in Vitro and in Vivo (pages 281–290)

      ROBERT L. JESSE, KATHY LOESSER, DAVID M. EICH, YONG ZHEN QIAN, MICHAEL L. HESS and JOHN E. NESTLER

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb17388.x-i1

  8. Poster Papers

    1. Top of page
    2. Poster Papers
    3. Part I. Age-Dependent Changes in Circulating DHEA and DHEA Biosynthesis
    4. Part II. DHEA and Neurologic Function
    5. Part III. Physiology of DHEA Metabolism
    6. Part IV. Biochemical Modes of Action for DHEA and Selected Metabolic Actions
    7. Part V. DHEA, Immunology, and Aging
    8. Part VI. DHEA and the Atherosclerosis of Aging
    9. Poster Papers
    1. Dehydroepiandrosterone Attenuates Study-Induced Declines in Insulin Sensitivity in Postmenopausal Women (pages 291–293)

      G. WRIGHT BATES Jr., ROBERT S. EGERMAN, EDWARD S. UMSTOT, JOHN E. BUSTER and PETER R. CASSON

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb17389.x-i1

    2. Cloning and Expression of Hamster Adrenal Cytochrome P450C17 cDNA (pages 294–296)

      MARIO CLOUTIER, ALAIN FLEURY, JEAN COURTEMANCHE, LYNE DUCHARME, J. IAN MASON and JEAN-GUY LEHOUX

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb17390.x-i1

    3. Dehydroepiandrosterone Enhances Influenza Immunization in Aged Mice (pages 297–299)

      H. D. DANENBERG, A. BEN-YEHUDA, Z. ZAKAY-RONES and G. FRIEDMAN

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb17391.x-i1

    4. Dehydroepiandrosterone Augments M1-Muscarinic Receptor-Stimulated Amyloid Precursor Protein Secretion in Desensitized PC12M1 Cells (pages 300–303)

      H. D. DANENBERG, R. HARING, E. HELDMAN, D. GURWITZ, D. BEN-NATHAN, Z. PITTEL, A. Zuckerman and A. FISHER

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb17392.x-i1

    5. Effects of Dehydroepiandrosterone Sulfate and Stress on Hippocampal Electrophysiological Plasticity (pages 304–307)

      DAVID M. DIAMOND, BERRILYN J. BRANCH, MONIKA FLESHNER and GREGORY M. ROSE

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb17393.x-i1

    6. Sex Differences in Dehydroepiandrosterone Metabolism in Rodents (pages 308–311)

      GERHARD HOBE, RENATE SCHÖN, KATHRIN UNDISZ, LUTZ BLEI and HANS-GEORG HILLESHEIM

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb17394.x-i1

    7. Effect of Dehydroepiandrosterone on Cyclic-Guanosine Monophosphate in Men of Advancing Age (pages 312–315)

      DANIELA JAKUBOWICZ, NUSEN BEER and RUFINO RENGIFO

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb17395.x-i1

    8. Effects of Aging and Long-Term Calorie Restriction on DHEA and DHEA Sulfate in Rhesus Monkeys (pages 319–322)

      MARK A. LANE, DONALD K. INGRAM and GEORGE S. ROTH

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb17397.x-i1

    9. Steroid Hormone Regulation of a Polyclonal TH2 Immune Response (pages 323–325)

      DAVID A. PADGETT, JOHN F. SHERIDAN and ROGER M. LORIA

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb17398.x-i1

    10. Effect of TGF-β on Dehydroepiandrosterone Sulfotransferase in Cultured Human Fetal Adrenal Cells (pages 326–328)

      C. R. PARKER Jr, A. K. STANKOVIC, C. N. FALANY and W. E. GRIZZLE

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb17399.x-i1

    11. DHEA Diminishes Fat Food Intake in Lean and Obese Zucker Rats (pages 329–331)

      J. R. PORTER and F. SVEC

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb17400.x-i1

    12. Effect of Dehydroepiandrosterone on Rat Thyroxine Binding Globulin, a Protein Upregulated during Aging (pages 335–336)

      ROGER VRANCKX, PATRICIA MECHIGHEL and LIA SAVU

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb17402.x-i1

    13. Antidepressant and Cognition-Enhancing Effects of DHEA in Major Depression (pages 337–339)

      O. M. WOLKOWITZ, V. I. REUS, E. ROBERTS, F. MANFREDI, T. CHAN, S. ORMISTON, R. JOHNSON, J. CANICK, L. BRIZENDINE and H. WEINGARTNER

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb17403.x-i1

    14. Effects of Dehydroepiandrosterone on MNU-Induced Breast Cancer in Sprague-Dawley Rats (pages 340–341)

      R. A. LUBET, D. M. McCORMICK, G. M. GORDON, C. GRUBBS, X-D LEI, R. A. PROUGH, V. E. STEELE, G. J. KELLOFF, C. F. THOMAS and R. D. MOON

      Article first published online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1995.tb17404.x-i1

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