Annals of the New York Academy of Sciences

Cover image for Annals of the New York Academy of Sciences

October 1996

Volume 801 Cellular and Molecular Mechanisms of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetamines

Pages xi–xi, 1–451

    1. Preface (page xi)

      Syed F. Ali

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1996.tb17426.x

  1. Part I: Molecular Mechanisms of Drug Addiction

    1. Top of page
    2. Part I: Molecular Mechanisms of Drug Addiction
    3. Part II: Signal Transduction, G-Proteins, Opioids and Drugs of Abuse
    4. Part III: Pharmacokinetics and Neuronal Markers in Substituted Amphetamine-Induced Neurotoxicity
    5. Part IV: Neuroprotection in Methamphetamine-Induced Neurotoxicity
    6. Part V: Neurotoxicity of the Anti-Addictive Drug Ibogaine
    7. Part VI: Pre- and Postnatal Exposure of Drugs of Abuse
    8. Part VII: Glutamate, NMDA, Histamine and Methamphetamine Neurotoxicity
    9. Part VIII: Neurochemical and Neurobehavioral Correlates of Drugs of Abuse
    10. Part IX: Clinical Studies of Drugs of Abuse
    1. Novel Transcription Factors Are Induced by Chronic Cocaine Treatment (pages 1–12)

      BRUCE T. HOPE

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1996.tb17427.x

    2. Effect of Acute and Chronic Administration of Methamphetamine on Activator Protein-1 Binding Activities in the Rat Brain Regions (pages 13–28)

      KAZUFUMI AKIYAMA, TAKESHI ISHIHARA and KENICHI KASHIHARA

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1996.tb17428.x

    3. Functional Changes in Neuronal Systems Induced by Phencyclidine Administration (pages 29–38)

      TOSHITAKA NABESHIMA, KIYOYUKI KITAICHI and YUKIHIRO NODA

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1996.tb17429.x

    4. A Genetic Approach to Study Mechanisms of Cocaine Action (pages 51–63)

      MING XU, XIU-TI HU, DONALD C. COOPER, FRANCIS J. WHITE and SUSUMU TONEGAWA

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1996.tb17431.x

    5. Structure, 5'-Upstream Sequence and Chromosomal Assignment of the Human 14.3.3 η Chain Gene in Relation to the Effects of Methamphetamine (pages 64–75)

      TATSUYUKI MURATAKE, SHIGENOBU HAYASHI, TOMIO ICHIKAWA, TOSHIRO KUMANISHI, YUKA ICHIMURA, RYOZO KUWANO, SHINSEI MINOSHIMA, NOBUYOSHI SHIMIZU and YASUO TAKAHASHI

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1996.tb17432.x

    6. Neurobiological Actions of Cocaine in the Hippocampus (pages 76–94)

      EMMANUEL S. ONAIVI, CASSANDRA BISHOP-ROBINSON, EVANGELINE D. MOTLEY, AMITABHA CHAKRABARTI and SANIKA S. CHIRWA

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1996.tb17433.x

  2. Part II: Signal Transduction, G-Proteins, Opioids and Drugs of Abuse

    1. Top of page
    2. Part I: Molecular Mechanisms of Drug Addiction
    3. Part II: Signal Transduction, G-Proteins, Opioids and Drugs of Abuse
    4. Part III: Pharmacokinetics and Neuronal Markers in Substituted Amphetamine-Induced Neurotoxicity
    5. Part IV: Neuroprotection in Methamphetamine-Induced Neurotoxicity
    6. Part V: Neurotoxicity of the Anti-Addictive Drug Ibogaine
    7. Part VI: Pre- and Postnatal Exposure of Drugs of Abuse
    8. Part VII: Glutamate, NMDA, Histamine and Methamphetamine Neurotoxicity
    9. Part VIII: Neurochemical and Neurobehavioral Correlates of Drugs of Abuse
    10. Part IX: Clinical Studies of Drugs of Abuse
    1. Comparison of the Three Mouse G-Protein-Activated K+ (GIRK) Channels and Functional Couplings of the Opioid Receptors with the GIRKI Channel (pages 95–109)

      KAZUTAKA IKEDA, TORU KOBAYASHI, TOMIO ICHIKAWA, HIROSHI USUI, SATOSHI ABE and TOSHIRO KUMANISHI

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1996.tb17434.x

    2. Alteration of G Protein Subclass mRNAs in Methamphetamine–Induced Behavioral Sensitization (pages 110–115)

      HIROTO IWASA, SHUICHI KIKUCHI, SHUJI HASEGAWA, KAORI SUZUKI and TOSHIO SATO

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1996.tb17435.x

  3. Part III: Pharmacokinetics and Neuronal Markers in Substituted Amphetamine-Induced Neurotoxicity

    1. Top of page
    2. Part I: Molecular Mechanisms of Drug Addiction
    3. Part II: Signal Transduction, G-Proteins, Opioids and Drugs of Abuse
    4. Part III: Pharmacokinetics and Neuronal Markers in Substituted Amphetamine-Induced Neurotoxicity
    5. Part IV: Neuroprotection in Methamphetamine-Induced Neurotoxicity
    6. Part V: Neurotoxicity of the Anti-Addictive Drug Ibogaine
    7. Part VI: Pre- and Postnatal Exposure of Drugs of Abuse
    8. Part VII: Glutamate, NMDA, Histamine and Methamphetamine Neurotoxicity
    9. Part VIII: Neurochemical and Neurobehavioral Correlates of Drugs of Abuse
    10. Part IX: Clinical Studies of Drugs of Abuse
  4. Part IV: Neuroprotection in Methamphetamine-Induced Neurotoxicity

    1. Top of page
    2. Part I: Molecular Mechanisms of Drug Addiction
    3. Part II: Signal Transduction, G-Proteins, Opioids and Drugs of Abuse
    4. Part III: Pharmacokinetics and Neuronal Markers in Substituted Amphetamine-Induced Neurotoxicity
    5. Part IV: Neuroprotection in Methamphetamine-Induced Neurotoxicity
    6. Part V: Neurotoxicity of the Anti-Addictive Drug Ibogaine
    7. Part VI: Pre- and Postnatal Exposure of Drugs of Abuse
    8. Part VII: Glutamate, NMDA, Histamine and Methamphetamine Neurotoxicity
    9. Part VIII: Neurochemical and Neurobehavioral Correlates of Drugs of Abuse
    10. Part IX: Clinical Studies of Drugs of Abuse
    1. Me thamphe tarnine-Induced Dopaminergic Toxicity in Mice : Role of Environmental Temperature and Pharmacological Agents (pages 187–198)

      SYED F. ALI, GLENN D. NEWPORT and WILLIAM SLIKKER JR.

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1996.tb17441.x

    2. Lack of Neuroprotective Effect of σ Receptor Ligands in the Neurotoxicity of p-Chloroamphetamine in Rat Braina (pages 199–204)

      NATSUKO NARITA, KENJI HASHIMOTO, MASAOMI IYO, YOSHIO MINABE and KOSUKE YAMAZAKI

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1996.tb17442.x

  5. Part V: Neurotoxicity of the Anti-Addictive Drug Ibogaine

    1. Top of page
    2. Part I: Molecular Mechanisms of Drug Addiction
    3. Part II: Signal Transduction, G-Proteins, Opioids and Drugs of Abuse
    4. Part III: Pharmacokinetics and Neuronal Markers in Substituted Amphetamine-Induced Neurotoxicity
    5. Part IV: Neuroprotection in Methamphetamine-Induced Neurotoxicity
    6. Part V: Neurotoxicity of the Anti-Addictive Drug Ibogaine
    7. Part VI: Pre- and Postnatal Exposure of Drugs of Abuse
    8. Part VII: Glutamate, NMDA, Histamine and Methamphetamine Neurotoxicity
    9. Part VIII: Neurochemical and Neurobehavioral Correlates of Drugs of Abuse
    10. Part IX: Clinical Studies of Drugs of Abuse
    1. Acute and Chronic Administration of Ibogaine to the Rat Results in Astrogliosis That Is Not Confined to the Cerebellar Vermis (pages 205–216)

      JAMES P. O'CALLAGHAN, TINA S. ROGERS, LARRY E. RODMAN and JOHN G. PAGE

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1996.tb17443.x

    2. Ibogaine Produces Neurodegeneration in Rat, but Not Mouse, Cerebellum : Neurohistological Biomarkers of Purkinje Cell Loss (pages 217–226)

      A. C. SCALLET, X. YE, R. ROUNTREE, P. NONY and S. F. ALI

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1996.tb17444.x

  6. Part VI: Pre- and Postnatal Exposure of Drugs of Abuse

    1. Top of page
    2. Part I: Molecular Mechanisms of Drug Addiction
    3. Part II: Signal Transduction, G-Proteins, Opioids and Drugs of Abuse
    4. Part III: Pharmacokinetics and Neuronal Markers in Substituted Amphetamine-Induced Neurotoxicity
    5. Part IV: Neuroprotection in Methamphetamine-Induced Neurotoxicity
    6. Part V: Neurotoxicity of the Anti-Addictive Drug Ibogaine
    7. Part VI: Pre- and Postnatal Exposure of Drugs of Abuse
    8. Part VII: Glutamate, NMDA, Histamine and Methamphetamine Neurotoxicity
    9. Part VIII: Neurochemical and Neurobehavioral Correlates of Drugs of Abuse
    10. Part IX: Clinical Studies of Drugs of Abuse
    1. Vascular Disruption in the Retina of Rats and Humans (pages 274–288)

      A. SILVA-ARAÚJO and M. A. TAVARES

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1996.tb17448.x

    2. The Effects of Prenatal Cocaine Exposure on Dopaminergic Challenge and Receptor Binding in Wistar Rats (pages 289–300)

      K. A. BENSON, S. F. ALI and M. C. WILSON

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1996.tb17449.x

    3. Chronic Cocaine Exposure throughout Gestation in the Rhesus Monkey : Pregnancy Outcomes and Offspring Behavior (pages 301–309)

      MERLE G. PAULE, MICHAEL P. GILLAM, ZBIGNIEW BINIENDA and PAUL MORRIS

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1996.tb17450.x

  7. Part VII: Glutamate, NMDA, Histamine and Methamphetamine Neurotoxicity

    1. Top of page
    2. Part I: Molecular Mechanisms of Drug Addiction
    3. Part II: Signal Transduction, G-Proteins, Opioids and Drugs of Abuse
    4. Part III: Pharmacokinetics and Neuronal Markers in Substituted Amphetamine-Induced Neurotoxicity
    5. Part IV: Neuroprotection in Methamphetamine-Induced Neurotoxicity
    6. Part V: Neurotoxicity of the Anti-Addictive Drug Ibogaine
    7. Part VI: Pre- and Postnatal Exposure of Drugs of Abuse
    8. Part VII: Glutamate, NMDA, Histamine and Methamphetamine Neurotoxicity
    9. Part VIII: Neurochemical and Neurobehavioral Correlates of Drugs of Abuse
    10. Part IX: Clinical Studies of Drugs of Abuse
    1. Increased Glutamate Transporter (GLT-1) Immunoreactivity in the Rat Striatum after Repeated Intermittent Administration of Methamphetamine (pages 310–314)

      N. NISHINO, Y. SHIRAI, Y. KAJIMOTO, N. KITAMURA, H. YAMAMOTO, C-Q. YANG and O. SHIRAKAWA

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1996.tb17451.x

    2. The Role of Glutamate in the Neurotoxic Effects of Methamphetamine (pages 315–326)

      T. OHMORI, T. ABEKAWA and T. KOYAMA

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1996.tb17452.x

    3. Non-aminergic Effects of Amphetamine on the NMDA Receptor in Primary Cultured Cortical Cells (pages 327–339)

      HIDEKO YAMAMOTO, TOSHIFUMI YAMAMOTO, KAORI GOJI, XIANHONG YANG, NOBUTOSHI KAWAI, ATSUOMI BABA and TAKASHI MOROJI

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1996.tb17453.x

    4. One-Way Cross-Sensitization and Cross-Tolerance to Seizure Activity from Cocaine to Lidocaine (pages 340–352)

      KAZUAKI SHIMOSATO, SATORU WATANABE, RODNEY J. MARLEY and TAIICHI SAITO

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1996.tb17454.x

    5. The Role of the Brain Histaminergic Neuron System in Methamphetamine-Induced Behavioral Sensitization in Rats (pages 353–360)

      CHIHIRO ITO, MITSUMOTO SATO, KENJI ONODERA and TAKEHIKO WATANABE

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1996.tb17455.x

  8. Part VIII: Neurochemical and Neurobehavioral Correlates of Drugs of Abuse

    1. Top of page
    2. Part I: Molecular Mechanisms of Drug Addiction
    3. Part II: Signal Transduction, G-Proteins, Opioids and Drugs of Abuse
    4. Part III: Pharmacokinetics and Neuronal Markers in Substituted Amphetamine-Induced Neurotoxicity
    5. Part IV: Neuroprotection in Methamphetamine-Induced Neurotoxicity
    6. Part V: Neurotoxicity of the Anti-Addictive Drug Ibogaine
    7. Part VI: Pre- and Postnatal Exposure of Drugs of Abuse
    8. Part VII: Glutamate, NMDA, Histamine and Methamphetamine Neurotoxicity
    9. Part VIII: Neurochemical and Neurobehavioral Correlates of Drugs of Abuse
    10. Part IX: Clinical Studies of Drugs of Abuse
    1. Neurochemical Analysis of the Psychotoxicity of Methamphetamine and Cocaine by Microdialysis in the Rat Brain (pages 361–370)

      AKIRA SHIMADA, KAZUKO YAMAGUCHI and TOMOR YANAGITA

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1996.tb17456.x

    2. Neurochemical Analysis of the Tyrosine Hydroxylase Expression in Methamphetamine-Sensitized Rats (pages 371–376)

      F. FUKAMAUCHI, M. ISHIMARU, T. HASHIMOTO and K. OBATA

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1996.tb17457.x

    3. Does an Increase of Cyclic AMP Prevent Methamphetamine-Induced Behavioral Sensitization in Rats? (pages 377–383)

      MASAOMI IYO, YING BI, KENJI HASHIMOTO, SHIN-ICHIRO TOMITAKA, TOSHIYA INADA and SUSUMU FUKUI

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1996.tb17458.x

    4. Serotonergic Modulations on Acute or Subchronic Methamphetamine-Induced Striatal 3-Methoxytyramine Levels in Mice (pages 384–387)

      TADAIMI MORIMASA, TAKAO KANEYUKI, NAOTO UEMURA, SHIGEYUKI NAKANO and TOSHIKIYO SHOHMORI

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1996.tb17459.x

    5. Dissection of Dopamine and Cocaine Binding Sites on the Rat Dopamine Transporter Expressed in COS Cells (pages 388–393)

      SHIGEO KITAYAMA, KATSUYA MORITA, TOSHIHIRO DOHI, JIA-BEI WANG, STEPHEN C. DAVIS and GEORGE R. UHL

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1996.tb17460.x

    6. Alterations in Electroencephalographic Signals and Monoamine Concentrations in the Rat Brain Following Cocaine and Methamphetamine Treatment (pages 394–400)

      ZBIGNIEW BINIENDA, JENNIFER A. SANDBERG, WILLIAM SLIKKER JR. and SYED F. ALI

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1996.tb17461.x

    7. Positron Emission Tomography Study of the Alterations in Brain Distribution of [11C]Methamphetamine in Methamphetamine-Sensitized Dog (pages 401–408)

      HITOSHI NAKAMURA, TAKANORI HISHINUMA, YOSHIHISA TOMIOKA, TATSUO IDO, REN IWATA, YOSHIHITO FUNAKI, MASATOSHI ITOH, TAKEHIKO FUJIWARA, KAZUHIKO YANAI, MITSUMOTO SATO, YOHTARO NUMACHI, SUMIKO YOSHIDA and MICHINAO MIZUGAKI

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1996.tb17462.x

  9. Part IX: Clinical Studies of Drugs of Abuse

    1. Top of page
    2. Part I: Molecular Mechanisms of Drug Addiction
    3. Part II: Signal Transduction, G-Proteins, Opioids and Drugs of Abuse
    4. Part III: Pharmacokinetics and Neuronal Markers in Substituted Amphetamine-Induced Neurotoxicity
    5. Part IV: Neuroprotection in Methamphetamine-Induced Neurotoxicity
    6. Part V: Neurotoxicity of the Anti-Addictive Drug Ibogaine
    7. Part VI: Pre- and Postnatal Exposure of Drugs of Abuse
    8. Part VII: Glutamate, NMDA, Histamine and Methamphetamine Neurotoxicity
    9. Part VIII: Neurochemical and Neurobehavioral Correlates of Drugs of Abuse
    10. Part IX: Clinical Studies of Drugs of Abuse
    1. Monoamine Neurotransmitter Function and Spontaneous Recurrence of Methamphetamine Psychosis (pages 415–429)

      KUNIO YUI, KIMIHIKO GOTO, SHIGENORI IKEMOTO and TAKEO ISHIGURO

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1996.tb17464.x

    2. Plasma Methionine Enkephalin-Like Immunoreactivity in Patients with Methamphetamine Psychosis (pages 430–440)

      MASAFUMI KATAYAMA, HIROSHI ONISHI, SEIJI KOIDE, TOSHIHIRO KAI, HIROSHI HASHIMOTO, YOSHIHIRO NAKAMURA, SAKAE YAMAGAMI, HIROFUMI KARIYAMA and YUKIO KAWAKITA

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1996.tb17465.x

    3. Proton MR Spectroscopy in Solvent Abusers (pages 441–451)

      S. NODA, N. YAMANOUCHI, S. OKADA, K. KODAMA, A. MURAKAMI, H. SEKINE, T. SAKAMOTO, N. KOMATSU, T. SATO, H. IKEHIRA and F. MORITA

      Version of Record online: 17 DEC 2006 | DOI: 10.1111/j.1749-6632.1996.tb17466.x

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