Annals of the New York Academy of Sciences

Cover image for Annals of the New York Academy of Sciences

May 1998

Volume 844 THE NEUROCHEMISTRY OF DRUGS OF ABUSE: COCAINE, IBOGAINE, AND SUBSTITUTED AMPHETAMINES

Pages x–x, 1–355

  1. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Preface

    1. Top of page
    2. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Preface
    3. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Part I. Gene Expression and Molecular Mechanisms of Drug Addiction
    4. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Part II. Drugs of Abuse and Medication Development: Cocaine
    5. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Part III. Role of Free Radicals in Drugs of Abuse-Induced Neurotoxicity
    6. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Part IV. Specific Neuronal Markers in Substituted Amphetamines-Induced Neurotoxicity
    7. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Part V. Drugs of Abuse and Medication Development: Ibogaine
    8. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Part VI. Prenatal Exposure and Postnatal Outcome
    1. Preface (page x)

      Syed F. Ali

      Article first published online: 7 FEB 2006 | DOI: 10.1111/j.1749-6632.1998.tb08215.x

  2. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Part I. Gene Expression and Molecular Mechanisms of Drug Addiction

    1. Top of page
    2. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Preface
    3. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Part I. Gene Expression and Molecular Mechanisms of Drug Addiction
    4. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Part II. Drugs of Abuse and Medication Development: Cocaine
    5. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Part III. Role of Free Radicals in Drugs of Abuse-Induced Neurotoxicity
    6. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Part IV. Specific Neuronal Markers in Substituted Amphetamines-Induced Neurotoxicity
    7. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Part V. Drugs of Abuse and Medication Development: Ibogaine
    8. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Part VI. Prenatal Exposure and Postnatal Outcome
    1. Immunohistochemical Changes of the Transcription Regulatory Factors in Rat Striatum after Methamphetamine Administration (pages 21–26)

      TATSUYUKI MURATAKE, KAZUHIKO TOYOOKA, SHIGENOBU HAYASHI, TOMIO ICHIKAWA, TOSHIRO KUMANISHI and YASUO TAKAHASHI

      Article first published online: 7 FEB 2006 | DOI: 10.1111/j.1749-6632.1998.tb08218.x

  3. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Part II. Drugs of Abuse and Medication Development: Cocaine

    1. Top of page
    2. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Preface
    3. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Part I. Gene Expression and Molecular Mechanisms of Drug Addiction
    4. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Part II. Drugs of Abuse and Medication Development: Cocaine
    5. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Part III. Role of Free Radicals in Drugs of Abuse-Induced Neurotoxicity
    6. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Part IV. Specific Neuronal Markers in Substituted Amphetamines-Induced Neurotoxicity
    7. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Part V. Drugs of Abuse and Medication Development: Ibogaine
    8. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Part VI. Prenatal Exposure and Postnatal Outcome
    1. Phentermine and Fenfluramine: Preclinical Studies in Animal Models of Cocaine Addiction (pages 59–74)

      RICHARD B. ROTHMAN, GREGORY I. ELMER, TONI S. SHIPPENBERG, WILLIAM REA and MICHAEL H. BAUMANN

      Article first published online: 7 FEB 2006 | DOI: 10.1111/j.1749-6632.1998.tb08222.x

  4. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Part III. Role of Free Radicals in Drugs of Abuse-Induced Neurotoxicity

    1. Top of page
    2. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Preface
    3. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Part I. Gene Expression and Molecular Mechanisms of Drug Addiction
    4. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Part II. Drugs of Abuse and Medication Development: Cocaine
    5. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Part III. Role of Free Radicals in Drugs of Abuse-Induced Neurotoxicity
    6. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Part IV. Specific Neuronal Markers in Substituted Amphetamines-Induced Neurotoxicity
    7. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Part V. Drugs of Abuse and Medication Development: Ibogaine
    8. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Part VI. Prenatal Exposure and Postnatal Outcome
    1. Methamphetamine-Induced Rapid and Reversible Reduction in the Activities of Tryptophan Hydroxylase and Dopamine Transporters: Oxidative Consequences? (pages 103–107)

      GLEN R. HANSON, JAMES W. GIBB, RYAN R. METZGER, JERRY M. KOKOSHKA and ANNETTE E. FLECKENSTEIN

      Article first published online: 7 FEB 2006 | DOI: 10.1111/j.1749-6632.1998.tb08225.x

    2. A Selective Regional Response of Cultured Astrocytes to Methamphetamine (pages 108–121)

      ALFREDA STADLIN, JOSEPHINE W.S. LAU and Y. K. SZETO

      Article first published online: 7 FEB 2006 | DOI: 10.1111/j.1749-6632.1998.tb08226.x

    3. Role of Calpain in Spinal Cord Injury: Effects of Calpain and Free Radical Inhibitors (pages 131–137)

      N. L. BANIK, D. C. SHIELDS, S. RAY, B. DAVIS, D. MATZELLE, G. WILFORD and E. L. HOGAN

      Article first published online: 7 FEB 2006 | DOI: 10.1111/j.1749-6632.1998.tb08228.x

  5. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Part IV. Specific Neuronal Markers in Substituted Amphetamines-Induced Neurotoxicity

    1. Top of page
    2. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Preface
    3. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Part I. Gene Expression and Molecular Mechanisms of Drug Addiction
    4. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Part II. Drugs of Abuse and Medication Development: Cocaine
    5. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Part III. Role of Free Radicals in Drugs of Abuse-Induced Neurotoxicity
    6. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Part IV. Specific Neuronal Markers in Substituted Amphetamines-Induced Neurotoxicity
    7. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Part V. Drugs of Abuse and Medication Development: Ibogaine
    8. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Part VI. Prenatal Exposure and Postnatal Outcome
    1. In Vivo Correlates of Central Serotonin Function after High-Dose Fenfluramine Administration (pages 138–152)

      MICHAEL H. BAUMANN, MARIO A. AYESTAS and RICHARD B. ROTHMAN

      Article first published online: 7 FEB 2006 | DOI: 10.1111/j.1749-6632.1998.tb08229.x

    2. The Impact of Gender and Estrogen on Striatal Dopaminergic Neurotoxicity (pages 153–165)

      DIANE B. MILLER, SYED F. ALI, JAMES P. O'CALLAGHAN and SUSAN C. LAWS

      Article first published online: 7 FEB 2006 | DOI: 10.1111/j.1749-6632.1998.tb08230.x

    3. Noradrenergic Modulation of Methamphetamine-Induced Striatal Dopamine Depletion (pages 166–177)

      FRANCESCO FORNAI, MARIA GRAZIA ALESSANDRÌ, MARIA TILDE TORRAC, LUCIA BASSI, VERA SCALORI and GIOVANNI UMBERTO CORSINI

      Article first published online: 7 FEB 2006 | DOI: 10.1111/j.1749-6632.1998.tb08231.x

    4. The Effects of Cocaine on Nonhuman Primate Brain Function Are Age Dependent (pages 178–182)

      MERLE G. PAULE, MICHAEL P. GILLAM and PAUL MORRIS

      Article first published online: 7 FEB 2006 | DOI: 10.1111/j.1749-6632.1998.tb08232.x

    5. Acute Effects of Dexfenfluramine (d-FEN) and Methylenedioxymethamphetamine (MDMA) before and after Short-Course, High-Dose Treatment (pages 183–190)

      DAVID L. FREDERICK, SYED F. ALI, MICHAEL P. GILLAM, JEFF GOSSETT, WILLIAM SLIKKER JR. and MERLE G. PAULE

      Article first published online: 7 FEB 2006 | DOI: 10.1111/j.1749-6632.1998.tb08233.x

    6. Influence of Concurrent Heroin and Cocaine Abuse on the Adrenergic and Serotonergic Systems in Man (pages 208–213)

      T.R. A. MERCADO, C.A. FONTES RIBEIRO, T. MORGADINHO and M.A. V. ABREU

      Article first published online: 7 FEB 2006 | DOI: 10.1111/j.1749-6632.1998.tb08236.x

  6. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Part V. Drugs of Abuse and Medication Development: Ibogaine

    1. Top of page
    2. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Preface
    3. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Part I. Gene Expression and Molecular Mechanisms of Drug Addiction
    4. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Part II. Drugs of Abuse and Medication Development: Cocaine
    5. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Part III. Role of Free Radicals in Drugs of Abuse-Induced Neurotoxicity
    6. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Part IV. Specific Neuronal Markers in Substituted Amphetamines-Induced Neurotoxicity
    7. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Part V. Drugs of Abuse and Medication Development: Ibogaine
    8. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Part VI. Prenatal Exposure and Postnatal Outcome
    1. Mechanisms of Antiaddictive Actions of Ibogaine (pages 214–226)

      STANLEY D. GLICK and ISABELLE M. MAISONNEUVE

      Article first published online: 7 FEB 2006 | DOI: 10.1111/j.1749-6632.1998.tb08237.x

    2. In Vivo Ibogaine Blockade and In Vitro PKC Action of Cocaine (pages 227–244)

      EMMANUEL S. ONAIVI, SYED F. ALI and AMITABHA CHAKRABARTI

      Article first published online: 7 FEB 2006 | DOI: 10.1111/j.1749-6632.1998.tb08238.x

    3. Neurochemical and Neuroendocrine Effects of Ibogaine in Rats: Comparison to MK-801 (pages 252–264)

      MICHAEL H. BAUMANN, RICHARD B. ROTHMAN and SYED F. ALI

      Article first published online: 7 FEB 2006 | DOI: 10.1111/j.1749-6632.1998.tb08240.x

    4. Alteration in Electroencephalogram and Monoamine Concentrations in Rat Brain following Ibogaine Treatment (pages 265–273)

      ZBIGNIEW BINIENDA, MICHAEL A. BEAUDOIN, BRETT T. THORN, D. REBECCA PRAPURNA, JOHN R. JOHNSON, C. MATTHEW FOGLE, WILLIAM SLIKKER JR. and SYED F. ALI

      Article first published online: 7 FEB 2006 | DOI: 10.1111/j.1749-6632.1998.tb08241.x

    5. Medication Development of Ibogaine as a Pharmacotherapy for Drug Dependence (pages 274–292)

      DEBORAH C. MASH, CRAIG A. KOVERA, BILLY E. BUCK, MICHAEL D. NORENBERG, PAUL SHAPSHAK, W. LEE HEARN and JUAN SANCHEZ-RAMOS

      Article first published online: 7 FEB 2006 | DOI: 10.1111/j.1749-6632.1998.tb08242.x

  7. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Part VI. Prenatal Exposure and Postnatal Outcome

    1. Top of page
    2. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Preface
    3. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Part I. Gene Expression and Molecular Mechanisms of Drug Addiction
    4. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Part II. Drugs of Abuse and Medication Development: Cocaine
    5. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Part III. Role of Free Radicals in Drugs of Abuse-Induced Neurotoxicity
    6. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Part IV. Specific Neuronal Markers in Substituted Amphetamines-Induced Neurotoxicity
    7. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Part V. Drugs of Abuse and Medication Development: Ibogaine
    8. The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetaminesa: Part VI. Prenatal Exposure and Postnatal Outcome
    1. Prenatal Cocaine Exposure Affects Postnatal Dopaminergic Systems in Various Regions of the Rat Brain (pages 293–302)

      SUN-JO CHOI, ELIZABETH MAZZIO, MALAK G. KOLTA and KARAM F.A. SOLIMAN

      Article first published online: 7 FEB 2006 | DOI: 10.1111/j.1749-6632.1998.tb08243.x

    2. Developmental Exposure to Methamphetamine: A Neonatal Model in the Rat (pages 310–313)

      J. GOMES-DA-SILVA, M. C. SILVA and M. A. TAVARES

      Article first published online: 7 FEB 2006 | DOI: 10.1111/j.1749-6632.1998.tb08245.x

    3. Uterine Position Determines the Extent of Dopamine Reduction after Chronic Prenatal Cocaine Exposure (pages 314–323)

      JACK W. LIPTON, HEATHER S. ROBIE, ZAODUNG LING, DEBRA E. WEESE-MAYER and PAUL M. CARVEY

      Article first published online: 7 FEB 2006 | DOI: 10.1111/j.1749-6632.1998.tb08246.x

    4. Gestational Cocaine Exposure Alters Postnatal Pituitary-Adrenal Axis Activity and Stress Endurance in Rats (pages 336–345)

      SUN-JO CHOI, ELIZABETH A. MAZZIO, RENEE R. REAMS and KARAM F.A. SOLIMAN

      Article first published online: 7 FEB 2006 | DOI: 10.1111/j.1749-6632.1998.tb08248.x

    5. Repeated Administration of Cocaine Alters Dopamine Uptake and Release in the Striatum Nucleus Accumbens (pages 346–355)

      LYNNE H. CLAY, ELIZABETH A. MAZZIO, MALAK G. KOLTA and KARAM F.A. SOLIMAN

      Article first published online: 7 FEB 2006 | DOI: 10.1111/j.1749-6632.1998.tb08249.x

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