Annals of the New York Academy of Sciences

Cover image for Annals of the New York Academy of Sciences

November 1999

Volume 892 THE METABOLIC SYNDROME X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defects

Pages ix–x, 1–336

  1. Frontmatter

    1. Top of page
    2. Frontmatter
    3. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Introduction
    4. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Part I. Overview of the Physiology of the Metabolic Syndrome
    5. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Part II. Hypertension and Predisposition to the Metabolic Syndrome
    6. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Part III. Adipose Cell Biochemistry and Syndrome X
    7. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Part IV. Regulation of Insulin Receptor Action and Syndrome X
    8. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Part V. Potential Animal Models of Syndrome X: Role of the Central Nervous System
    9. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Part V. Potential Animal Models of Syndrome X: Role of the Central Nervous System: Poster Papers
    1. Preface (pages ix–x)

      Barbara Caleen Hansen, JoAnne Saye and Lawrence P. Wennogle

      Version of Record online: 6 FEB 2006 | DOI: 10.1111/j.1749-6632.1999.tb07781.x

  2. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Introduction

    1. Top of page
    2. Frontmatter
    3. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Introduction
    4. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Part I. Overview of the Physiology of the Metabolic Syndrome
    5. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Part II. Hypertension and Predisposition to the Metabolic Syndrome
    6. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Part III. Adipose Cell Biochemistry and Syndrome X
    7. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Part IV. Regulation of Insulin Receptor Action and Syndrome X
    8. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Part V. Potential Animal Models of Syndrome X: Role of the Central Nervous System
    9. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Part V. Potential Animal Models of Syndrome X: Role of the Central Nervous System: Poster Papers
    1. The Metabolic Syndrome X (pages 1–24)

      BARBARA CALEEN HANSEN

      Version of Record online: 6 FEB 2006 | DOI: 10.1111/j.1749-6632.1999.tb07782.x

  3. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Part I. Overview of the Physiology of the Metabolic Syndrome

    1. Top of page
    2. Frontmatter
    3. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Introduction
    4. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Part I. Overview of the Physiology of the Metabolic Syndrome
    5. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Part II. Hypertension and Predisposition to the Metabolic Syndrome
    6. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Part III. Adipose Cell Biochemistry and Syndrome X
    7. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Part IV. Regulation of Insulin Receptor Action and Syndrome X
    8. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Part V. Potential Animal Models of Syndrome X: Role of the Central Nervous System
    9. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Part V. Potential Animal Models of Syndrome X: Role of the Central Nervous System: Poster Papers
  4. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Part II. Hypertension and Predisposition to the Metabolic Syndrome

    1. Top of page
    2. Frontmatter
    3. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Introduction
    4. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Part I. Overview of the Physiology of the Metabolic Syndrome
    5. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Part II. Hypertension and Predisposition to the Metabolic Syndrome
    6. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Part III. Adipose Cell Biochemistry and Syndrome X
    7. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Part IV. Regulation of Insulin Receptor Action and Syndrome X
    8. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Part V. Potential Animal Models of Syndrome X: Role of the Central Nervous System
    9. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Part V. Potential Animal Models of Syndrome X: Role of the Central Nervous System: Poster Papers
    1. Mechanisms of Hypertension and Kidney Disease in Obesity (pages 91–107)

      JOHN E. HALL, MICHAEL W. BRANDS and JEFFREY R. HENEGAR

      Version of Record online: 6 FEB 2006 | DOI: 10.1111/j.1749-6632.1999.tb07788.x

  5. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Part III. Adipose Cell Biochemistry and Syndrome X

    1. Top of page
    2. Frontmatter
    3. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Introduction
    4. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Part I. Overview of the Physiology of the Metabolic Syndrome
    5. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Part II. Hypertension and Predisposition to the Metabolic Syndrome
    6. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Part III. Adipose Cell Biochemistry and Syndrome X
    7. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Part IV. Regulation of Insulin Receptor Action and Syndrome X
    8. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Part V. Potential Animal Models of Syndrome X: Role of the Central Nervous System
    9. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Part V. Potential Animal Models of Syndrome X: Role of the Central Nervous System: Poster Papers
    1. Insulin Signaling and Action in Fat Cells: Associations with Insulin Resistance and Type 2 Diabetes (pages 119–126)

      ULF SMITH, METTE AXELSEN, EUGENIA CARVALHO, BJÖRN ELIASSON, PER-ANDERS JANSSON and CHRISTIAN WESSLAU

      Version of Record online: 6 FEB 2006 | DOI: 10.1111/j.1749-6632.1999.tb07790.x

    2. Role of PPARγ in Regulating Adipocyte Differentiation and Insulin-Responsive Glucose Uptake (pages 134–145)

      JONATHAN K. HAMM, AMR K. EL JACK, PAUL F. PILCH and STEPHEN R. FARMER

      Version of Record online: 6 FEB 2006 | DOI: 10.1111/j.1749-6632.1999.tb07792.x

    3. On the Control of Lipolysis in Adipocytes (pages 155–168)

      CONSTANTINE LONDOS, DAWN L. BRASAEMLE, CHARLES J. SCHULTZ, DIANE C. ADLER-WAILES, DANIEL M. LEVIN, ALAN R. KIMMEL and CRISTINA M. RONDINONE

      Version of Record online: 6 FEB 2006 | DOI: 10.1111/j.1749-6632.1999.tb07794.x

  6. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Part IV. Regulation of Insulin Receptor Action and Syndrome X

    1. Top of page
    2. Frontmatter
    3. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Introduction
    4. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Part I. Overview of the Physiology of the Metabolic Syndrome
    5. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Part II. Hypertension and Predisposition to the Metabolic Syndrome
    6. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Part III. Adipose Cell Biochemistry and Syndrome X
    7. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Part IV. Regulation of Insulin Receptor Action and Syndrome X
    8. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Part V. Potential Animal Models of Syndrome X: Role of the Central Nervous System
    9. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Part V. Potential Animal Models of Syndrome X: Role of the Central Nervous System: Poster Papers
    1. Signaling Pathways Mediating Insulin-Stimulated Glucose Transport (pages 169–186)

      SCOTT A. SUMMERS, VIRAVUTH P. YIN, EILEEN L. WHITEMAN, LUIS A. GARZA, HAN CHO, ROBYN L. TUTTLE and MORRIS J. BIRNBAUM

      Version of Record online: 6 FEB 2006 | DOI: 10.1111/j.1749-6632.1999.tb07795.x

    2. Role of PC-1 in The Etiology of Insulin Resistance (pages 204–222)

      IRA D. GOLDFINE, BETTY A. MADDUX, JACK F. YOUNGREN, VINCENZO TRISCHITTA and LUCIA FRITTITTA

      Version of Record online: 6 FEB 2006 | DOI: 10.1111/j.1749-6632.1999.tb07797.x

  7. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Part V. Potential Animal Models of Syndrome X: Role of the Central Nervous System

    1. Top of page
    2. Frontmatter
    3. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Introduction
    4. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Part I. Overview of the Physiology of the Metabolic Syndrome
    5. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Part II. Hypertension and Predisposition to the Metabolic Syndrome
    6. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Part III. Adipose Cell Biochemistry and Syndrome X
    7. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Part IV. Regulation of Insulin Receptor Action and Syndrome X
    8. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Part V. Potential Animal Models of Syndrome X: Role of the Central Nervous System
    9. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Part V. Potential Animal Models of Syndrome X: Role of the Central Nervous System: Poster Papers
    1. Transgenic Mice Lacking White Fat: Models for Understanding Human Lipoatrophic Diabetes (pages 289–296)

      MARC L. REITMAN, MARK M. MASON, JAIDEEP MOITRA, OKSANA GAVRILOVA, BERNICE MARCUS-SAMUELS, MICHAEL ECKHAUS and CHARLES VINSON

      Version of Record online: 6 FEB 2006 | DOI: 10.1111/j.1749-6632.1999.tb07802.x

    2. Hypothalamic Origin of the Metabolic Syndrome X (pages 297–307)

      PER BJÖRNTORP and ROLAND ROSMOND

      Version of Record online: 6 FEB 2006 | DOI: 10.1111/j.1749-6632.1999.tb07803.x

  8. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Part V. Potential Animal Models of Syndrome X: Role of the Central Nervous System: Poster Papers

    1. Top of page
    2. Frontmatter
    3. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Introduction
    4. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Part I. Overview of the Physiology of the Metabolic Syndrome
    5. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Part II. Hypertension and Predisposition to the Metabolic Syndrome
    6. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Part III. Adipose Cell Biochemistry and Syndrome X
    7. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Part IV. Regulation of Insulin Receptor Action and Syndrome X
    8. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Part V. Potential Animal Models of Syndrome X: Role of the Central Nervous System
    9. The Metabolic Syndrome X: Convergence of Insulin Resistance, Glucose Intolerance, Hypertension, Obesity, and Dyslipidemias-Searching for the Underlying Defectsa: Part V. Potential Animal Models of Syndrome X: Role of the Central Nervous System: Poster Papers
    1. Pharmacological Interference with Hepatic Glucose Production (pages 312–314)

      H.-J. BURGER, G. SCHUBERT, H. HEMMERLE, W. KRAMER and A. W. HERLING

      Version of Record online: 6 FEB 2006 | DOI: 10.1111/j.1749-6632.1999.tb07805.x

    2. The SHROB Model of Syndrome X: Effects of Excess Dietary Sucrose (pages 315–318)

      PAUL ERNSBERGER, R. J. KOLETSKY, D. D. KLINE, D. M. BEDOL and J. E. FRIEDMAN

      Version of Record online: 6 FEB 2006 | DOI: 10.1111/j.1749-6632.1999.tb07806.x

    3. Very Low Density Lipoprotein Overproduction Is Maximally Expressed in Early Insulin Resistant States (pages 319–322)

      JENS PIETZSCH, ULRICH JULIUS, CHRISTIAN KIRCH, SABINE FISCHER and MARKOLF HANEFELD

      Version of Record online: 6 FEB 2006 | DOI: 10.1111/j.1749-6632.1999.tb07807.x

    4. Early Pubertal Development and Overweight in Girls (pages 327–329)

      K. M. PIRKE, H. WURMSER, A. ANGST, R. LAESSLE and S. E. TRIMBORN

      Version of Record online: 6 FEB 2006 | DOI: 10.1111/j.1749-6632.1999.tb07809.x

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