Annals of the New York Academy of Sciences

Cover image for Annals of the New York Academy of Sciences

April 2000

Volume 903 VASCULAR FACTORS IN ALZHEIMER'S DISEASE

Pages xiii–xix, 1–552

  1. Frontmatter

    1. Top of page
    2. Frontmatter
    3. Vascular Factors in Alzheimer's Diseasea: Part I. Alzheimer's Disease: Vascular Concepts, Cellular Issues, and Genetics (Plenary Lectures)
    4. Vascular Factors in Alzheimer's Diseasea: Part II. Vascular Pathology in Alzheimer's Disease: Recent Developments
    5. Vascular Factors in Alzheimer's Diseasea: Part III. Cerebral Amyloid Angiopathy and Factors Regulating Cerebral Amyloidosis
    6. Vascular Factors in Alzheimer's Diseasea: Part IV. Apolipoprotein E and Genetics in Cerebral Amyloid Angiopathy and Alzheimer's Disease
    7. Vascular Factors in Alzheimer's Diseasea: Part V. VAD: Clinical Aspects, Vascular Lesions, and Imaging
    8. Vascular Factors in Alzheimer's Diseasea: Part VI. Vasculopathies and CADASIL
    9. Vascular Factors in Alzheimer's Diseasea: Part VII. Transgenic Animal and In Vitro Models: Vascular Effects
    10. Vascular Factors in Alzheimer's Diseasea: Part VIII. Cholinergic Mechanisms and Vascular Pathology
    11. Vascular Factors in Alzheimer's Diseasea: Part IX. Cardiovascular Risk Factors and Vascular Pathophysiology in Dementia
    12. Vascular Factors in Alzheimer's Diseasea: Part X. White Matter Lesions and Dementia
    13. Vascular Factors in Alzheimer's Diseasea: Part XI. Diagnostic, Preventative, and Treatment Strategies in Alzheimer's Disease and Vascular Dementia
    1. Henryk Miroslaw Wisniewski, 1931–1999 (pages xiii–xvi)

      R. N. Kalaria and A. E. Oakley

      Article first published online: 30 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb06341.x

    2. Preface (pages xvii–xix)

      Raj N. Kalaria

      Article first published online: 30 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb06342.x

  2. Vascular Factors in Alzheimer's Diseasea: Part I. Alzheimer's Disease: Vascular Concepts, Cellular Issues, and Genetics (Plenary Lectures)

    1. Top of page
    2. Frontmatter
    3. Vascular Factors in Alzheimer's Diseasea: Part I. Alzheimer's Disease: Vascular Concepts, Cellular Issues, and Genetics (Plenary Lectures)
    4. Vascular Factors in Alzheimer's Diseasea: Part II. Vascular Pathology in Alzheimer's Disease: Recent Developments
    5. Vascular Factors in Alzheimer's Diseasea: Part III. Cerebral Amyloid Angiopathy and Factors Regulating Cerebral Amyloidosis
    6. Vascular Factors in Alzheimer's Diseasea: Part IV. Apolipoprotein E and Genetics in Cerebral Amyloid Angiopathy and Alzheimer's Disease
    7. Vascular Factors in Alzheimer's Diseasea: Part V. VAD: Clinical Aspects, Vascular Lesions, and Imaging
    8. Vascular Factors in Alzheimer's Diseasea: Part VI. Vasculopathies and CADASIL
    9. Vascular Factors in Alzheimer's Diseasea: Part VII. Transgenic Animal and In Vitro Models: Vascular Effects
    10. Vascular Factors in Alzheimer's Diseasea: Part VIII. Cholinergic Mechanisms and Vascular Pathology
    11. Vascular Factors in Alzheimer's Diseasea: Part IX. Cardiovascular Risk Factors and Vascular Pathophysiology in Dementia
    12. Vascular Factors in Alzheimer's Diseasea: Part X. White Matter Lesions and Dementia
    13. Vascular Factors in Alzheimer's Diseasea: Part XI. Diagnostic, Preventative, and Treatment Strategies in Alzheimer's Disease and Vascular Dementia
    1. Vascular Factors in Cognitive Impairment-Where Are We Now? (pages 1–5)

      VLADIMIR HACHINSKI and DAVID MUNOZ

      Article first published online: 30 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb06343.x

    2. Role of Perivascular Cells and Myocytes in Vascular Amyloidosis (pages 6–18)

      H. M. WISNIEWSKI, J. WEGIEL, A. W. VORBRODT, B. MAZUR-KOLECKA and J. FRACKOWIAK

      Article first published online: 30 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb06344.x

    3. Cascading Glia Reactions: a Common Pathomechanism and Its Differentiated Control by Cyclic Nucleotide Signaling (pages 24–33)

      PETER SCHUBERT, TADAO MORINO, HIROFUMI MIYAZAKI, TADANORI OGATA, YOICHI NAKAMURA, CRISTINA MARCHINI and STEFANO FERRONI

      Article first published online: 30 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb06346.x

  3. Vascular Factors in Alzheimer's Diseasea: Part II. Vascular Pathology in Alzheimer's Disease: Recent Developments

    1. Top of page
    2. Frontmatter
    3. Vascular Factors in Alzheimer's Diseasea: Part I. Alzheimer's Disease: Vascular Concepts, Cellular Issues, and Genetics (Plenary Lectures)
    4. Vascular Factors in Alzheimer's Diseasea: Part II. Vascular Pathology in Alzheimer's Disease: Recent Developments
    5. Vascular Factors in Alzheimer's Diseasea: Part III. Cerebral Amyloid Angiopathy and Factors Regulating Cerebral Amyloidosis
    6. Vascular Factors in Alzheimer's Diseasea: Part IV. Apolipoprotein E and Genetics in Cerebral Amyloid Angiopathy and Alzheimer's Disease
    7. Vascular Factors in Alzheimer's Diseasea: Part V. VAD: Clinical Aspects, Vascular Lesions, and Imaging
    8. Vascular Factors in Alzheimer's Diseasea: Part VI. Vasculopathies and CADASIL
    9. Vascular Factors in Alzheimer's Diseasea: Part VII. Transgenic Animal and In Vitro Models: Vascular Effects
    10. Vascular Factors in Alzheimer's Diseasea: Part VIII. Cholinergic Mechanisms and Vascular Pathology
    11. Vascular Factors in Alzheimer's Diseasea: Part IX. Cardiovascular Risk Factors and Vascular Pathophysiology in Dementia
    12. Vascular Factors in Alzheimer's Diseasea: Part X. White Matter Lesions and Dementia
    13. Vascular Factors in Alzheimer's Diseasea: Part XI. Diagnostic, Preventative, and Treatment Strategies in Alzheimer's Disease and Vascular Dementia
    1. Cerebrovascular Pathology in Alzheimer's Disease and Leukoaraiosis (pages 39–45)

      WILLIAM R. BROWN, DIXON M. MOODY, CLARA R. THORE and VENKATA R. CHALLA

      Article first published online: 30 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb06348.x

    2. Role of Blood Vessels in Producing Pathological Changes in the Brain with Alzheimer's Disease (pages 46–54)

      TAIHEI MIYAKAWA, TAKEMI KIMURA, SHINICHI HIRATA, NOBORU FUJISE, TSUNEHIKO ONO, KOKO ISHIZUKA and JUN NAKABAYASHI

      Article first published online: 30 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb06349.x

    3. Cerebrovasculature-mediated Neuronal Cell Death (pages 55–60)

      PAULA GRAMMAS, ULRICH REIMANN-PHILIPP and PAUL H. WEIGEL

      Article first published online: 30 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb06350.x

    4. Role of Aberrant Nitric Oxide Synthase-3 Expression in Cerebrovascular Degeneration and Vascular-mediated Injury in Alzheimer's Disease (pages 61–71)

      SUZANNE M. DE LA MONTE, YOON K. SOHN, DANNIE ETIENNE, JOANNY KRAFT and JACK R. WANDS

      Article first published online: 30 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb06351.x

    5. Similar Ultrastructural Breakdown of Cerebrocortical Capillaries in Alzheimer's Disease, Parkinson's Disease, and Experimental Hypertension: What is the Functional Link? (pages 72–82)

      ESZTER FARKAS, GINEKE I. DE JONG, ETELKA APRÓ, ROB A.I. DE VOS, ERNST N.H. JANSEN STEUR and PAUL G.M. LUITEN

      Article first published online: 30 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb06352.x

  4. Vascular Factors in Alzheimer's Diseasea: Part III. Cerebral Amyloid Angiopathy and Factors Regulating Cerebral Amyloidosis

    1. Top of page
    2. Frontmatter
    3. Vascular Factors in Alzheimer's Diseasea: Part I. Alzheimer's Disease: Vascular Concepts, Cellular Issues, and Genetics (Plenary Lectures)
    4. Vascular Factors in Alzheimer's Diseasea: Part II. Vascular Pathology in Alzheimer's Disease: Recent Developments
    5. Vascular Factors in Alzheimer's Diseasea: Part III. Cerebral Amyloid Angiopathy and Factors Regulating Cerebral Amyloidosis
    6. Vascular Factors in Alzheimer's Diseasea: Part IV. Apolipoprotein E and Genetics in Cerebral Amyloid Angiopathy and Alzheimer's Disease
    7. Vascular Factors in Alzheimer's Diseasea: Part V. VAD: Clinical Aspects, Vascular Lesions, and Imaging
    8. Vascular Factors in Alzheimer's Diseasea: Part VI. Vasculopathies and CADASIL
    9. Vascular Factors in Alzheimer's Diseasea: Part VII. Transgenic Animal and In Vitro Models: Vascular Effects
    10. Vascular Factors in Alzheimer's Diseasea: Part VIII. Cholinergic Mechanisms and Vascular Pathology
    11. Vascular Factors in Alzheimer's Diseasea: Part IX. Cardiovascular Risk Factors and Vascular Pathophysiology in Dementia
    12. Vascular Factors in Alzheimer's Diseasea: Part X. White Matter Lesions and Dementia
    13. Vascular Factors in Alzheimer's Diseasea: Part XI. Diagnostic, Preventative, and Treatment Strategies in Alzheimer's Disease and Vascular Dementia
    1. Cerebrovascular Smooth Muscle Cell Surface Fibrillar Aβ: Alteration of the Proteolytic Environment in the Cerebral Vessel Wall (pages 89–96)

      WILLIAM E. VAN NOSTRAND, JERRY MELCHOR, MATTHEW WAGNER and JUDIANNE DAVIS

      Article first published online: 30 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb06354.x

    2. Aβ Vasoactivity: An Inflammatory Reaction (pages 97–109)

      DANIEL PARIS, TERRENCE TOWN, TIMOTHY PARKER, JAMES HUMPHREY and MICHAEL MULLAN

      Article first published online: 30 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb06355.x

    3. Traumatic Brain Injury Elevates the Alzheimer's Amyloid Peptide Aβ42 in Human CSF: A Possible Role for Nerve Cell Injury (pages 118–122)

      M. R. EMMERLING, M. C. MORGANTI-KOSSMANN, T. KOSSMANN, P. F. STAHEL, M. D. WATSON, L. M. EVANS, P. D. MEHTA, K. SPIEGEL, Y.-M. KUO, A. E. ROHER and C. A. RABY

      Article first published online: 30 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb06357.x

    4. Prospects for Noninvasive Imaging of Brain Amyloid β in Alzheimer's Disease (pages 123–128)

      R. P. FRIEDLAND, J. SHI, J. C. LAMANNA, M. A. SMITH and G. PERRY

      Article first published online: 30 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb06358.x

    5. A Newly Formed Amyloidogenic Fragment due to a Stop Codon Mutation Causes Familial British Dementia (pages 129–137)

      J. GHISO, R. VIDAL, A. ROSTAGNO, S. MEAD, T. RÉVÉSZ, G. PLANT and B. FRANGIONE

      Article first published online: 30 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb06359.x

    6. Relationship between Severe Amyloid Angiopathy, Apolipoprotein E Genotype, and Vascular Lesions in Alzheimer's Disease (pages 138–143)

      J. M. OLICHNEY, L. A. HANSEN, J. H. LEE, C. R. HOFSTETTER, R. KATZMAN and L. J. THAL

      Article first published online: 30 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb06360.x

    7. Plasma β-Amyloid Peptide, Transforming Growth Factor-β1, and Risk for Cerebral Amyloid Angiopathy (pages 144–149)

      STEVEN M. GREENBERG, HYUN-SOON CHO, HEATHER C. O'DONNELL, JONATHAN ROSAND, ALAN Z. SEGAL, LINDA H. YOUNKIN, STEVEN G. YOUNKIN and G. WILLIAM REBECK

      Article first published online: 30 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb06361.x

    8. The Effect of Iron and Aluminum on Transferrin and Other Serum Proteins as Revealed by Isoelectric Focusing Gel Electrophoresis (pages 150–155)

      S. J. VAN RENSBURG, M. E. CARSTENS, F.C. V. POTOCNIK and J.J. F. TALJAARD

      Article first published online: 30 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb06362.x

    9. Aβ Vasoactivity in Vivo (pages 156–163)

      ZHIMING SUO, GEORGE SU, ANDON PLACZEK, AMY KUNDTZ, JAMES HUMPHREY, FIONA CRAWFORD and MIKE MULLAN

      Article first published online: 30 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb06363.x

    10. Cytochemistry of Intraplatelet Ca++ Spots as a Peripheral Marker of Age-related Brain Impairment (pages 164–166)

      CARLO BERTONI-FREDDARI, TIZIANA CASOLI, PATRIZIA FATTORETTI, LUCIANO GALEAZZI, GIUSEPPINA DI STEFANO, NATASCIA BELARDINELLI, EUGENIO PUCCI and MARIO SIGNORINO

      Article first published online: 30 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb06364.x

  5. Vascular Factors in Alzheimer's Diseasea: Part IV. Apolipoprotein E and Genetics in Cerebral Amyloid Angiopathy and Alzheimer's Disease

    1. Top of page
    2. Frontmatter
    3. Vascular Factors in Alzheimer's Diseasea: Part I. Alzheimer's Disease: Vascular Concepts, Cellular Issues, and Genetics (Plenary Lectures)
    4. Vascular Factors in Alzheimer's Diseasea: Part II. Vascular Pathology in Alzheimer's Disease: Recent Developments
    5. Vascular Factors in Alzheimer's Diseasea: Part III. Cerebral Amyloid Angiopathy and Factors Regulating Cerebral Amyloidosis
    6. Vascular Factors in Alzheimer's Diseasea: Part IV. Apolipoprotein E and Genetics in Cerebral Amyloid Angiopathy and Alzheimer's Disease
    7. Vascular Factors in Alzheimer's Diseasea: Part V. VAD: Clinical Aspects, Vascular Lesions, and Imaging
    8. Vascular Factors in Alzheimer's Diseasea: Part VI. Vasculopathies and CADASIL
    9. Vascular Factors in Alzheimer's Diseasea: Part VII. Transgenic Animal and In Vitro Models: Vascular Effects
    10. Vascular Factors in Alzheimer's Diseasea: Part VIII. Cholinergic Mechanisms and Vascular Pathology
    11. Vascular Factors in Alzheimer's Diseasea: Part IX. Cardiovascular Risk Factors and Vascular Pathophysiology in Dementia
    12. Vascular Factors in Alzheimer's Diseasea: Part X. White Matter Lesions and Dementia
    13. Vascular Factors in Alzheimer's Diseasea: Part XI. Diagnostic, Preventative, and Treatment Strategies in Alzheimer's Disease and Vascular Dementia
    1. Lipoproteins in the Central Nervous System (pages 167–175)

      MARY JO LADU, CATHERINE REARDON, LINDA VAN ELDIK, ANNE M. FAGAN, GUOJUN BU, DAVID HOLTZMAN and GODFREY S. GETZ

      Article first published online: 30 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb06365.x

    2. Apolipoprotein E Genotype and Cerebral Amyloid Angiopathy-related Hemorrhage (pages 176–179)

      MARK O. McCARRON and JAMES A.R. NICOLL

      Article first published online: 30 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb06366.x

    3. Amyloid-β-induced Degeneration of Human Brain Pericytes Is Dependent on the Apolipoprotein E Genotype (pages 187–199)

      MARCEL M. VERBEEK, WILLIAM E. VAN NOSTRAND, IRENE OTTE-HÖLLER, PIETER WESSELING and ROBERT M. W. DE WAAL

      Article first published online: 30 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb06368.x

    4. Earlier Age of Onset of Alzheimer's Disease in Patients with Both the Transferrin C2 and Apolipoprotein E-ɛ4 Alleles (pages 200–203)

      S. J. VAN RENSBURG, F.C. V. POTOCNIK, J.N. P. DE VILLIERS, M. J. KOTZE and J.J. F. TALJAARD

      Article first published online: 30 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb06369.x

    5. Insulin Effects on Glucose Metabolism, Memory, and Plasma Amyloid Precursor Protein in Alzheimer's Disease Differ According to Apolipoprotein-E Genotype (pages 222–228)

      SUZANNE CRAFT, SANJAY ASTHANA, GERARD SCHELLENBERG, LAURA BAKER, MONIQUE CHERRIER, ADAM A. BOYT, RALPH N. MARTINS, MURRAY RASKIND, ELAINE PESKIND and STEPHEN PLYMATE

      Article first published online: 30 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb06371.x

  6. Vascular Factors in Alzheimer's Diseasea: Part V. VAD: Clinical Aspects, Vascular Lesions, and Imaging

    1. Top of page
    2. Frontmatter
    3. Vascular Factors in Alzheimer's Diseasea: Part I. Alzheimer's Disease: Vascular Concepts, Cellular Issues, and Genetics (Plenary Lectures)
    4. Vascular Factors in Alzheimer's Diseasea: Part II. Vascular Pathology in Alzheimer's Disease: Recent Developments
    5. Vascular Factors in Alzheimer's Diseasea: Part III. Cerebral Amyloid Angiopathy and Factors Regulating Cerebral Amyloidosis
    6. Vascular Factors in Alzheimer's Diseasea: Part IV. Apolipoprotein E and Genetics in Cerebral Amyloid Angiopathy and Alzheimer's Disease
    7. Vascular Factors in Alzheimer's Diseasea: Part V. VAD: Clinical Aspects, Vascular Lesions, and Imaging
    8. Vascular Factors in Alzheimer's Diseasea: Part VI. Vasculopathies and CADASIL
    9. Vascular Factors in Alzheimer's Diseasea: Part VII. Transgenic Animal and In Vitro Models: Vascular Effects
    10. Vascular Factors in Alzheimer's Diseasea: Part VIII. Cholinergic Mechanisms and Vascular Pathology
    11. Vascular Factors in Alzheimer's Diseasea: Part IX. Cardiovascular Risk Factors and Vascular Pathophysiology in Dementia
    12. Vascular Factors in Alzheimer's Diseasea: Part X. White Matter Lesions and Dementia
    13. Vascular Factors in Alzheimer's Diseasea: Part XI. Diagnostic, Preventative, and Treatment Strategies in Alzheimer's Disease and Vascular Dementia
    1. Interface between Vascular Dementia and Alzheimer Syndrome: Nosologic Redefinition (pages 229–238)

      V. OLGA EMERY, EDWARD X. GILLIE and JOSEPH A. SMITH

      Article first published online: 30 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb06372.x

    2. Severity of Cardiovascular Disease, Apolipoprotein E Genotype, and Brain Pathology in Aging and Dementia (pages 244–251)

      IRINA ALAFUZOFF, SEPPO HELISALMI, ARTO MANNERMAA and HILKKA SOININEN

      Article first published online: 30 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb06374.x

    3. Can PET Data Differentiate Alzheimer's Disease from Vascular Dementia? (pages 252–261)

      KEN NAGATA, HIROSHI MARUYA, HIROMICHI YUYA, HIROO TERASHI, YASUNORI MITO, HARUHISA KATO, MIKA SATO, YUICHI SATOH, YASUHITO WATAHIKI, YUTAKA HIRATA, ERIKO YOKOYAMA and JUN HATAZAWA

      Article first published online: 30 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb06375.x

    4. Limitations of Clincal Criteria for the Diagnosis of Vascular Dementia in Clinical Trials: Is a Focus on Subcortical Vascular Dementia a Solution? (pages 262–272)

      TIMO ERKINJUNTTI, DOMENICO INZITARI, LEONARDO PANTONI, ANDERS WALLIN, PHILIP SCHELTENS, KENNETH ROCKWOOD and DAVID W. DESMOND

      Article first published online: 30 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb06376.x

  7. Vascular Factors in Alzheimer's Diseasea: Part VI. Vasculopathies and CADASIL

    1. Top of page
    2. Frontmatter
    3. Vascular Factors in Alzheimer's Diseasea: Part I. Alzheimer's Disease: Vascular Concepts, Cellular Issues, and Genetics (Plenary Lectures)
    4. Vascular Factors in Alzheimer's Diseasea: Part II. Vascular Pathology in Alzheimer's Disease: Recent Developments
    5. Vascular Factors in Alzheimer's Diseasea: Part III. Cerebral Amyloid Angiopathy and Factors Regulating Cerebral Amyloidosis
    6. Vascular Factors in Alzheimer's Diseasea: Part IV. Apolipoprotein E and Genetics in Cerebral Amyloid Angiopathy and Alzheimer's Disease
    7. Vascular Factors in Alzheimer's Diseasea: Part V. VAD: Clinical Aspects, Vascular Lesions, and Imaging
    8. Vascular Factors in Alzheimer's Diseasea: Part VI. Vasculopathies and CADASIL
    9. Vascular Factors in Alzheimer's Diseasea: Part VII. Transgenic Animal and In Vitro Models: Vascular Effects
    10. Vascular Factors in Alzheimer's Diseasea: Part VIII. Cholinergic Mechanisms and Vascular Pathology
    11. Vascular Factors in Alzheimer's Diseasea: Part IX. Cardiovascular Risk Factors and Vascular Pathophysiology in Dementia
    12. Vascular Factors in Alzheimer's Diseasea: Part X. White Matter Lesions and Dementia
    13. Vascular Factors in Alzheimer's Diseasea: Part XI. Diagnostic, Preventative, and Treatment Strategies in Alzheimer's Disease and Vascular Dementia
    1. Skin Biopsy Value and Leukoaraiosis (pages 285–292)

      M. M. RUCHOUX, P. BRULIN, E. LETEURTRE and C. A. MAURAGE

      Article first published online: 30 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb06378.x

    2. Hereditary Vascular Dementia Linked to Notch 3 Mutations: CADASIL in British Families (pages 293–298)

      N. J. THOMAS, C. M. MORRIS, F. SCARAVILLI, J. JOHANSSON, M. ROSSOR, R. DE LANGE, D. ST CLAIR, J. NICOLL, C. BLANK, A. COULTHARD, K. BUSHBY, P. G. INCE, D. BURN and R. N. KALARIA

      Article first published online: 30 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb06379.x

    3. Linear Relation between Cerebral Phosphocreatine Concentration and Memory Capacities during Permanent Brain Vessel Occlusions in Rats (pages 299–306)

      KONSTANZE PLASCHKE, SEONG-WOOK YUN, EIKE MARTIN, SIEGFRIED HOYER and HUBERT J. BARDENHEUER

      Article first published online: 30 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb06380.x

  8. Vascular Factors in Alzheimer's Diseasea: Part VII. Transgenic Animal and In Vitro Models: Vascular Effects

    1. Top of page
    2. Frontmatter
    3. Vascular Factors in Alzheimer's Diseasea: Part I. Alzheimer's Disease: Vascular Concepts, Cellular Issues, and Genetics (Plenary Lectures)
    4. Vascular Factors in Alzheimer's Diseasea: Part II. Vascular Pathology in Alzheimer's Disease: Recent Developments
    5. Vascular Factors in Alzheimer's Diseasea: Part III. Cerebral Amyloid Angiopathy and Factors Regulating Cerebral Amyloidosis
    6. Vascular Factors in Alzheimer's Diseasea: Part IV. Apolipoprotein E and Genetics in Cerebral Amyloid Angiopathy and Alzheimer's Disease
    7. Vascular Factors in Alzheimer's Diseasea: Part V. VAD: Clinical Aspects, Vascular Lesions, and Imaging
    8. Vascular Factors in Alzheimer's Diseasea: Part VI. Vasculopathies and CADASIL
    9. Vascular Factors in Alzheimer's Diseasea: Part VII. Transgenic Animal and In Vitro Models: Vascular Effects
    10. Vascular Factors in Alzheimer's Diseasea: Part VIII. Cholinergic Mechanisms and Vascular Pathology
    11. Vascular Factors in Alzheimer's Diseasea: Part IX. Cardiovascular Risk Factors and Vascular Pathophysiology in Dementia
    12. Vascular Factors in Alzheimer's Diseasea: Part X. White Matter Lesions and Dementia
    13. Vascular Factors in Alzheimer's Diseasea: Part XI. Diagnostic, Preventative, and Treatment Strategies in Alzheimer's Disease and Vascular Dementia
    1. Mechanisms of Cerebrovascular Amyloid Deposition: Lessons from Mouse Models (pages 307–316)

      PATRICK BURGERMEISTER, MICHAEL E. CALHOUN, DAVID T. WINKLER and MATHIAS JUCKER

      Article first published online: 30 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb06381.x

    2. Alterations of Alzheimer's Disease in the Cholesterol-fed Rabbit, Including Vascular Inflammation: Preliminary Observations (pages 335–344)

      D. LARRY SPARKS, YU-MIN KUO, ALEX ROHER, TIM MARTIN and RONALD J. LUKAS

      Article first published online: 30 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb06384.x

    3. Animal Model of Alzheimer-like Vascular Pathology and Inflammatory Reaction (pages 345–352)

      J. RHODIN, T. THOMAS, M. BRYANT and E. T. SUTTON

      Article first published online: 30 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb06385.x

  9. Vascular Factors in Alzheimer's Diseasea: Part VIII. Cholinergic Mechanisms and Vascular Pathology

    1. Top of page
    2. Frontmatter
    3. Vascular Factors in Alzheimer's Diseasea: Part I. Alzheimer's Disease: Vascular Concepts, Cellular Issues, and Genetics (Plenary Lectures)
    4. Vascular Factors in Alzheimer's Diseasea: Part II. Vascular Pathology in Alzheimer's Disease: Recent Developments
    5. Vascular Factors in Alzheimer's Diseasea: Part III. Cerebral Amyloid Angiopathy and Factors Regulating Cerebral Amyloidosis
    6. Vascular Factors in Alzheimer's Diseasea: Part IV. Apolipoprotein E and Genetics in Cerebral Amyloid Angiopathy and Alzheimer's Disease
    7. Vascular Factors in Alzheimer's Diseasea: Part V. VAD: Clinical Aspects, Vascular Lesions, and Imaging
    8. Vascular Factors in Alzheimer's Diseasea: Part VI. Vasculopathies and CADASIL
    9. Vascular Factors in Alzheimer's Diseasea: Part VII. Transgenic Animal and In Vitro Models: Vascular Effects
    10. Vascular Factors in Alzheimer's Diseasea: Part VIII. Cholinergic Mechanisms and Vascular Pathology
    11. Vascular Factors in Alzheimer's Diseasea: Part IX. Cardiovascular Risk Factors and Vascular Pathophysiology in Dementia
    12. Vascular Factors in Alzheimer's Diseasea: Part X. White Matter Lesions and Dementia
    13. Vascular Factors in Alzheimer's Diseasea: Part XI. Diagnostic, Preventative, and Treatment Strategies in Alzheimer's Disease and Vascular Dementia
    1. Cortical Cholinergic Denervation Elicits Vascular Aβ Deposition (pages 366–373)

      ALEX E. ROHER, YU-MIN KUO, PAMELA E. POTTER, MARK R. EMMERLING, ROBERT A. DURHAM, DOUGLAS G. WALKER, LUCIA I. SUE, WILLIAM G. HONER and THOMAS G. BEACH

      Article first published online: 30 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb06388.x

    2. Effect of a Memory-Enhancing Drug, AIT-082, on the Level of Synaptophysin (pages 387–393)

      D. K LAHIRI, Y.-W. GE and M. R. FARLOW

      Article first published online: 30 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb06390.x

  10. Vascular Factors in Alzheimer's Diseasea: Part IX. Cardiovascular Risk Factors and Vascular Pathophysiology in Dementia

    1. Top of page
    2. Frontmatter
    3. Vascular Factors in Alzheimer's Diseasea: Part I. Alzheimer's Disease: Vascular Concepts, Cellular Issues, and Genetics (Plenary Lectures)
    4. Vascular Factors in Alzheimer's Diseasea: Part II. Vascular Pathology in Alzheimer's Disease: Recent Developments
    5. Vascular Factors in Alzheimer's Diseasea: Part III. Cerebral Amyloid Angiopathy and Factors Regulating Cerebral Amyloidosis
    6. Vascular Factors in Alzheimer's Diseasea: Part IV. Apolipoprotein E and Genetics in Cerebral Amyloid Angiopathy and Alzheimer's Disease
    7. Vascular Factors in Alzheimer's Diseasea: Part V. VAD: Clinical Aspects, Vascular Lesions, and Imaging
    8. Vascular Factors in Alzheimer's Diseasea: Part VI. Vasculopathies and CADASIL
    9. Vascular Factors in Alzheimer's Diseasea: Part VII. Transgenic Animal and In Vitro Models: Vascular Effects
    10. Vascular Factors in Alzheimer's Diseasea: Part VIII. Cholinergic Mechanisms and Vascular Pathology
    11. Vascular Factors in Alzheimer's Diseasea: Part IX. Cardiovascular Risk Factors and Vascular Pathophysiology in Dementia
    12. Vascular Factors in Alzheimer's Diseasea: Part X. White Matter Lesions and Dementia
    13. Vascular Factors in Alzheimer's Diseasea: Part XI. Diagnostic, Preventative, and Treatment Strategies in Alzheimer's Disease and Vascular Dementia
    1. Plasma Total Homocysteine and Cognitive Performance in a Volunteer Elderly Population (pages 407–410)

      M. BUDGE, C. JOHNSTON, E. HOGERVORST, C. DE JAGER, E. MILWAIN, S. D. IVERSEN, L. BARNETSON, M. BUDGE, E. KING and A. D. SMITH

      Article first published online: 30 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb06392.x

    2. Cardiovascular and Other Risk Factors for Alzheimer's Disease and Vascular Dementia (pages 411–423)

      JOHN S. MEYER, GAIANE M. RAUCH, RONALD A. RAUCH, ANWARUL HAQUE and KATE CRAWFORD

      Article first published online: 30 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb06393.x

    3. The Renin Angiotensin System and Alzheimer's Disease (pages 437–441)

      PHILIPPE AMOUYEL, FLORENCE RICHARD, CLAUDINE BERR, ISABELLE DAVID-FROMENTIN and NICOLE HELBECQUE

      Article first published online: 30 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb06395.x

    4. Neurocardiovascular Instability, Hypotensive Episodes, and MRI Lesions in Neurodegenerative Dementia (pages 442–445)

      CLIVE BALLARD, JOHN O'BRIEN, BOB BARBER, PHILIP SCHELTENS, FIONA SHAW, IAN MCKEITH and ROSE ANNE KENNY

      Article first published online: 30 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb06396.x

    5. β-Amyloid Vasoactivity and Proinflammation in Microglia Can Be Blocked by cGMP-Elevating Agents (pages 446–450)

      DANIEL PARIS, TERRENCE TOWN, TIMOTHY PARKER, JAMES HUMPHREY and MICHAEL MULLAN

      Article first published online: 30 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb06397.x

    6. β-Amyloid Fragment 25–35 Induces Changes in Cytosolic Free Calcium in Human Platelets (pages 451–456)

      LUCIANO GALEAZZI, TIZIANA CASOLI, SERGIO GIUNTA, PATRIZIA FATTORETTI, NATASCIA GRACCIOTTI, UGO CASELLI and CARLO BERTONI-FREDDARI

      Article first published online: 30 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb06398.x

  11. Vascular Factors in Alzheimer's Diseasea: Part X. White Matter Lesions and Dementia

    1. Top of page
    2. Frontmatter
    3. Vascular Factors in Alzheimer's Diseasea: Part I. Alzheimer's Disease: Vascular Concepts, Cellular Issues, and Genetics (Plenary Lectures)
    4. Vascular Factors in Alzheimer's Diseasea: Part II. Vascular Pathology in Alzheimer's Disease: Recent Developments
    5. Vascular Factors in Alzheimer's Diseasea: Part III. Cerebral Amyloid Angiopathy and Factors Regulating Cerebral Amyloidosis
    6. Vascular Factors in Alzheimer's Diseasea: Part IV. Apolipoprotein E and Genetics in Cerebral Amyloid Angiopathy and Alzheimer's Disease
    7. Vascular Factors in Alzheimer's Diseasea: Part V. VAD: Clinical Aspects, Vascular Lesions, and Imaging
    8. Vascular Factors in Alzheimer's Diseasea: Part VI. Vasculopathies and CADASIL
    9. Vascular Factors in Alzheimer's Diseasea: Part VII. Transgenic Animal and In Vitro Models: Vascular Effects
    10. Vascular Factors in Alzheimer's Diseasea: Part VIII. Cholinergic Mechanisms and Vascular Pathology
    11. Vascular Factors in Alzheimer's Diseasea: Part IX. Cardiovascular Risk Factors and Vascular Pathophysiology in Dementia
    12. Vascular Factors in Alzheimer's Diseasea: Part X. White Matter Lesions and Dementia
    13. Vascular Factors in Alzheimer's Diseasea: Part XI. Diagnostic, Preventative, and Treatment Strategies in Alzheimer's Disease and Vascular Dementia
    1. Relevance of White Matter Changes to Pre- and Poststroke Dementia (pages 466–469)

      FLORENCE PASQUIER, HILDE HÉNON and DIDIER LEYS

      Article first published online: 30 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb06400.x

    2. Corpus Callosum Measurement as an in Vivo Indicator for Neocortical Neuronal Integrity, but not White Matter Pathology, in Alzheimer's Disease (pages 470–476)

      HARALD HAMPEL, STEFAN J. TEIPEL, GENE E. ALEXANDER, BARRY HORWITZ, PIETRO PIETRINI, HANNS HIPPIUS, HANS-JÜRGEN MÖLLER, MARK B. SCHAPIRO and STANLEY I. RAPOPORT

      Article first published online: 30 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb06401.x

    3. The Association between White Matter Lesions on Magnetic Resonance Imaging and Noncognitive Symptoms (pages 482–489)

      JOHN O'BRIEN, ROBERT PERRY, ROBERT BARBER, ANIL GHOLKAR and ALAN THOMAS

      Article first published online: 30 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb06403.x

    4. Neuropathological Findings in the Very Old: Results from the First 101 Brains of a Population-based Longitudinal Study of Dementing Disorders (pages 490–496)

      J. H. XUEREB, C. BRAYNE, C. DUFOUIL, H. GERTZ, C. WISCHIK, C. HARRINGTON, E. MUKAETOVA-LADINSKA, M. A. McGEE, A. O'SULLIVAN, D. O'CONNOR, E. S. PAYKEL and F. A. HUPPERT

      Article first published online: 30 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb06404.x

    5. Leukoaraiosis at Presentation and Disease Progression during Follow-up in Histologically Confirmed Cases of Dementia (pages 497–500)

      R. CLARKE, C. JOACHIM, M. ESIRI, J. MORRIS, H. BUNGAY, A. MOLYNEUX, M. BUDGE, C. FROST, E. KING, L. BARNETSON and A. D. SMITH

      Article first published online: 30 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb06405.x

  12. Vascular Factors in Alzheimer's Diseasea: Part XI. Diagnostic, Preventative, and Treatment Strategies in Alzheimer's Disease and Vascular Dementia

    1. Top of page
    2. Frontmatter
    3. Vascular Factors in Alzheimer's Diseasea: Part I. Alzheimer's Disease: Vascular Concepts, Cellular Issues, and Genetics (Plenary Lectures)
    4. Vascular Factors in Alzheimer's Diseasea: Part II. Vascular Pathology in Alzheimer's Disease: Recent Developments
    5. Vascular Factors in Alzheimer's Diseasea: Part III. Cerebral Amyloid Angiopathy and Factors Regulating Cerebral Amyloidosis
    6. Vascular Factors in Alzheimer's Diseasea: Part IV. Apolipoprotein E and Genetics in Cerebral Amyloid Angiopathy and Alzheimer's Disease
    7. Vascular Factors in Alzheimer's Diseasea: Part V. VAD: Clinical Aspects, Vascular Lesions, and Imaging
    8. Vascular Factors in Alzheimer's Diseasea: Part VI. Vasculopathies and CADASIL
    9. Vascular Factors in Alzheimer's Diseasea: Part VII. Transgenic Animal and In Vitro Models: Vascular Effects
    10. Vascular Factors in Alzheimer's Diseasea: Part VIII. Cholinergic Mechanisms and Vascular Pathology
    11. Vascular Factors in Alzheimer's Diseasea: Part IX. Cardiovascular Risk Factors and Vascular Pathophysiology in Dementia
    12. Vascular Factors in Alzheimer's Diseasea: Part X. White Matter Lesions and Dementia
    13. Vascular Factors in Alzheimer's Diseasea: Part XI. Diagnostic, Preventative, and Treatment Strategies in Alzheimer's Disease and Vascular Dementia
    1. Vascular Actions of Estrogen and Alzheimer's Disease (pages 501–509)

      T. THOMAS and J. RHODIN

      Article first published online: 30 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb06406.x

    2. Subcortical Vascular Dementia as a Specific Target for Clinical Trials (pages 510–521)

      DOMENICO INZITARI, TIMO ERKINJUNTTI, ANDERS WALLIN, TEODORO DEL SER, MARCO ROMANELLI and LEONARDO PANTONI

      Article first published online: 30 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb06407.x

    3. The Diagnosis of “Mixed” Dementia in the Consortium for the Investigation of Vascular Impairment of Cognition (CIVIC) (pages 522–528)

      K. ROCKWOOD, C. MACKNIGHT, C. WENTZEL, S. BLACK, R. BOUCHARD, S. GAUTHIER, H. FELDMAN, D. HOGAN, A. KERTESZ, P. MONTGOMERY and FOR THE CIVIC INVESTIGATORS

      Article first published online: 30 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb06408.x

    4. Alzheimer's Disease and Vascular Dementia: Some Points of Confluence (pages 547–552)

      HEDDA AGÜERO-TORRES and BENGT WINBLAD

      Article first published online: 30 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb06412.x

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