Annals of the New York Academy of Sciences

Cover image for Annals of the New York Academy of Sciences

December 2000

Volume 915 EPITHELIAL TRANSPORT AND BARRIER FUNCTION: PATHOMECHANISMS IN GASTROINTESTINAL DISORDERS

Pages xi–xii, 1–372

  1. Frontmatter

    1. Top of page
    2. Frontmatter
    3. Epithelial Transport and Barrier Function: Pathomechanisms in Gastrointestinal Disorders: Part I. Expression of Transporters and Regulation of Ion Transport
    4. Epithelial Transport and Barrier Function: Pathomechanisms in Gastrointestinal Disorders: Part I. Expression of Transporters and Regulation of Ion Transport: Extended Abstracts
    5. Epithelial Transport and Barrier Function: Pathomechanisms in Gastrointestinal Disorders: Part II. Structure and Regulation of the Intestinal Barrier
    6. Epithelial Transport and Barrier Function: Pathomechanisms in Gastrointestinal Disorders: Part III. Models for Studying Disturbed Transport and Barrier Properties
    7. Epithelial Transport and Barrier Function: Pathomechanisms in Gastrointestinal Disorders: Part III. Models for Studying Disturbed Transport and Barrier Properties: Extended Abstracts
    8. Epithelial Transport and Barrier Function: Pathomechanisms in Gastrointestinal Disorders: Part IV. Diarrheal Mechanisms in Gastrointestinal Diseases
    1. Preface (pages xi–xii)

      Jörg-Dieter Schulzke and Michael Fromm

      Version of Record online: 25 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb05218.x

  2. Epithelial Transport and Barrier Function: Pathomechanisms in Gastrointestinal Disorders: Part I. Expression of Transporters and Regulation of Ion Transport

    1. Top of page
    2. Frontmatter
    3. Epithelial Transport and Barrier Function: Pathomechanisms in Gastrointestinal Disorders: Part I. Expression of Transporters and Regulation of Ion Transport
    4. Epithelial Transport and Barrier Function: Pathomechanisms in Gastrointestinal Disorders: Part I. Expression of Transporters and Regulation of Ion Transport: Extended Abstracts
    5. Epithelial Transport and Barrier Function: Pathomechanisms in Gastrointestinal Disorders: Part II. Structure and Regulation of the Intestinal Barrier
    6. Epithelial Transport and Barrier Function: Pathomechanisms in Gastrointestinal Disorders: Part III. Models for Studying Disturbed Transport and Barrier Properties
    7. Epithelial Transport and Barrier Function: Pathomechanisms in Gastrointestinal Disorders: Part III. Models for Studying Disturbed Transport and Barrier Properties: Extended Abstracts
    8. Epithelial Transport and Barrier Function: Pathomechanisms in Gastrointestinal Disorders: Part IV. Diarrheal Mechanisms in Gastrointestinal Diseases
    1. Expression and Function of Na+HCO3 Cotransporters in the Gastrointestinal Tract (pages 1–14)

      URSULA SEIDLER, HEIDI ROSSMANN, PETRA JACOB, OLIVER BACHMANN, STEPHANIE CHRISTIANI, GEORG LAMPRECHT and MICHAEL GREGOR

      Version of Record online: 25 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb05219.x

    2. Characterization and Molecular Localization of Anion Transporters in Colonic Epithelial Cells (pages 15–29)

      VAZHAIKKURICHI M. RAJENDRAN and HENRY J. BINDER

      Version of Record online: 25 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb05220.x

    3. Short-Term Regulation of NHE3 by EGF and Protein Kinase C but Not Protein Kinase A Involves Vesicle Trafficking in Epithelial Cells and Fibroblasts (pages 30–42)

      M. DONOWITZ, A. JANECKI, S. AKHTER, M. E. CAVET, F. SANCHEZ, G. LAMPRECHT, M. ZIZAK, W. L. KWON, S. KHURANA, C. H.C. YUN and C. M. TSE

      Version of Record online: 25 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb05221.x

    4. Cl-Dependent Na-H Exchange: A Novel Colonic Crypt Transport Mechanism (pages 43–53)

      HENRY J. BINDER, VAZHAIKKURICHI M. RAJENDRAN and JOHN P. GEIBEL

      Version of Record online: 25 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb05222.x

    5. Coupling between Na+, Sugar, and Water Transport across the Intestine (pages 54–66)

      ERNEST M. WRIGHT and DONALD D. F. LOO

      Version of Record online: 25 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb05223.x

    6. Regulation of Chloride Secretion: Novel Pathways and Messengers (pages 67–76)

      STEPHEN J. KEELY and KIM E. BARRETT

      Version of Record online: 25 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb05224.x

  3. Epithelial Transport and Barrier Function: Pathomechanisms in Gastrointestinal Disorders: Part I. Expression of Transporters and Regulation of Ion Transport: Extended Abstracts

    1. Top of page
    2. Frontmatter
    3. Epithelial Transport and Barrier Function: Pathomechanisms in Gastrointestinal Disorders: Part I. Expression of Transporters and Regulation of Ion Transport
    4. Epithelial Transport and Barrier Function: Pathomechanisms in Gastrointestinal Disorders: Part I. Expression of Transporters and Regulation of Ion Transport: Extended Abstracts
    5. Epithelial Transport and Barrier Function: Pathomechanisms in Gastrointestinal Disorders: Part II. Structure and Regulation of the Intestinal Barrier
    6. Epithelial Transport and Barrier Function: Pathomechanisms in Gastrointestinal Disorders: Part III. Models for Studying Disturbed Transport and Barrier Properties
    7. Epithelial Transport and Barrier Function: Pathomechanisms in Gastrointestinal Disorders: Part III. Models for Studying Disturbed Transport and Barrier Properties: Extended Abstracts
    8. Epithelial Transport and Barrier Function: Pathomechanisms in Gastrointestinal Disorders: Part IV. Diarrheal Mechanisms in Gastrointestinal Diseases
    1. Three 5′-Variant mRNAs of Anion Exchanger AE2 in Stomach and Intestine of Mouse, Rabbit, and Rat (pages 81–91)

      HEIDI ROSSMANN, SETH L. ALPER, MANUELA NADER, ZHUO WANG, MICHAEL GREGOR and URSULA SEIDLER

      Version of Record online: 25 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb05226.x

    2. Differential Regulation of ENaC by Aldosterone in Rat Early and Late Distal Colon (pages 92–94)

      S. AMASHEH, H. J. EPPLE, J. MANKERTZ, K. DETJEN, M. GOLTZ, J. D. SCHULZKE and M. FROMM

      Version of Record online: 25 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb05227.x

    3. Epithelial Phosphate Transporters in Small Ruminants (pages 95–97)

      K. HUBER, C. WALTER, B. SCHRÖDER, J. BIBER, H. MURER and G. BREVES

      Version of Record online: 25 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb05228.x

    4. Inflammatory Mediators Influencing Submucosal Secretory Reflexes (pages 98–101)

      THOMAS FRIELING, ECKHARD WEBER and MICHAEL SCHEMANN

      Version of Record online: 25 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb05229.x

    5. Investigation of Motility and Secretion in Perfused Guinea Pig Colon ex Situ (pages 107–110)

      DETLEF WERMELSKIRCHEN and KERSTIN SCHNEIDER

      Version of Record online: 25 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb05231.x

    6. Effects of HIV Protease Inhibitors on Barrier Function in the Human Intestinal Cell Line HT-29/B6 (pages 117–122)

      H. BODE, W. SCHMIDT, J. D. SCHULZKE, M. FROMM, E. O. RIECKEN and R. ULLRICH

      Version of Record online: 25 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb05233.x

    7. Induction of Endothelial Barrier Function in Vitro (pages 123–128)

      G. KOCH, S. PRÄTZEL, M. RODE and B. M. KRÄLING

      Version of Record online: 25 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb05234.x

  4. Epithelial Transport and Barrier Function: Pathomechanisms in Gastrointestinal Disorders: Part II. Structure and Regulation of the Intestinal Barrier

    1. Top of page
    2. Frontmatter
    3. Epithelial Transport and Barrier Function: Pathomechanisms in Gastrointestinal Disorders: Part I. Expression of Transporters and Regulation of Ion Transport
    4. Epithelial Transport and Barrier Function: Pathomechanisms in Gastrointestinal Disorders: Part I. Expression of Transporters and Regulation of Ion Transport: Extended Abstracts
    5. Epithelial Transport and Barrier Function: Pathomechanisms in Gastrointestinal Disorders: Part II. Structure and Regulation of the Intestinal Barrier
    6. Epithelial Transport and Barrier Function: Pathomechanisms in Gastrointestinal Disorders: Part III. Models for Studying Disturbed Transport and Barrier Properties
    7. Epithelial Transport and Barrier Function: Pathomechanisms in Gastrointestinal Disorders: Part III. Models for Studying Disturbed Transport and Barrier Properties: Extended Abstracts
    8. Epithelial Transport and Barrier Function: Pathomechanisms in Gastrointestinal Disorders: Part IV. Diarrheal Mechanisms in Gastrointestinal Diseases
    1. The Structure and Function of Claudins, Cell Adhesion Molecules at Tight Junctions (pages 129–135)

      SHOICHIRO TSUKITA and MIKIO FURUSE

      Version of Record online: 25 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb05235.x

    2. Intestinal Cell Adhesion Molecules: Liver-Intestine Cadherin (pages 136–143)

      REINHARD GESSNER and RUDOLF TAUBER

      Version of Record online: 25 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb05236.x

    3. Molecular Diversity of Plaques of Epithelial-Adhering Junctions (pages 144–150)

      CAROLA M. BORRMANN, CLAUDIA MERTENS, ANSGAR SCHMIDT, LUTZ LANGBEIN, CAECILIA KUHN and WERNER W. FRANKE

      Version of Record online: 25 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb05237.x

    4. Neutrophil Migration across Intestinal Epithelium (pages 151–161)

      DAVID L. JAYE and CHARLES A. PARKOS

      Version of Record online: 25 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb05238.x

    5. Expression and Function of Death Receptors and Their Natural Ligands in the Intestine (pages 162–170)

      JÖRN STRÄTER and PETER MÖLLER

      Version of Record online: 25 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb05239.x

    6. Role of M Cells in Intestinal Barrier Function (pages 171–183)

      T. KUCHARZIK, N. LÜGERING, K. RAUTENBERG, A. LÜGERING, M. A. SCHMIDT, R. STOLL and W. DOMSCHKE

      Version of Record online: 25 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb05240.x

  5. Epithelial Transport and Barrier Function: Pathomechanisms in Gastrointestinal Disorders: Part III. Models for Studying Disturbed Transport and Barrier Properties

    1. Top of page
    2. Frontmatter
    3. Epithelial Transport and Barrier Function: Pathomechanisms in Gastrointestinal Disorders: Part I. Expression of Transporters and Regulation of Ion Transport
    4. Epithelial Transport and Barrier Function: Pathomechanisms in Gastrointestinal Disorders: Part I. Expression of Transporters and Regulation of Ion Transport: Extended Abstracts
    5. Epithelial Transport and Barrier Function: Pathomechanisms in Gastrointestinal Disorders: Part II. Structure and Regulation of the Intestinal Barrier
    6. Epithelial Transport and Barrier Function: Pathomechanisms in Gastrointestinal Disorders: Part III. Models for Studying Disturbed Transport and Barrier Properties
    7. Epithelial Transport and Barrier Function: Pathomechanisms in Gastrointestinal Disorders: Part III. Models for Studying Disturbed Transport and Barrier Properties: Extended Abstracts
    8. Epithelial Transport and Barrier Function: Pathomechanisms in Gastrointestinal Disorders: Part IV. Diarrheal Mechanisms in Gastrointestinal Diseases
    1. Epithelial Barrier Defects in HT-29/B6 Colonic Cell Monolayers Induced by Tumor Necrosis Factor-α (pages 193–203)

      ALFRED H. GITTER, KERSTIN BENDFELDT, HEINZ SCHMITZ, JöRG-DIETER SCHULZKE, CARL J. BENTZEL and MICHAEL FROMM

      Version of Record online: 25 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb05242.x

    2. Enhanced Expression of iNOS in Inflamed Colons of IL-2-Deficient Mice Does Not Impair Colonic Epithelial Barrier Function (pages 204–213)

      M. HARREN, C. BARMEYER, H. SCHMITZ, M. FROMM, I. HORAK, A. DIGNASS, M. JOHN, B. WIEDENMANN and J.-D. SCHULZKE

      Version of Record online: 25 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb05243.x

    3. Increased Tight Junction Permeability Can Result from Protein Kinase C Activation/Translocation and Act as a Tumor Promotional Event in Epithelial Cancers (pages 231–236)

      JAMES M. MULLIN, KATHLEEN V. LAUGHLIN, NICOLE GINANNI, COLLEEN W. MARANO, HILARY M. CLARKE and ALEJANDRO PERALTA SOLER

      Version of Record online: 25 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb05246.x

    4. Stress-Induced Decrease of the Intestinal Barrier Function: The Role of Muscarinic Receptor Activation (pages 237–246)

      JACK GROOT, PIETER BIJLSMA, ANNETTE VAN KALKEREN, AMANDA KILIAAN, PAUL SAUNDERS and MARY PERDUE

      Version of Record online: 25 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb05247.x

    5. Immunologically Mediated Transport of Ions and Macromolecules (pages 247–259)

      LINDA C. H. YU and MARY H. PERDUE

      Version of Record online: 25 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb05248.x

  6. Epithelial Transport and Barrier Function: Pathomechanisms in Gastrointestinal Disorders: Part III. Models for Studying Disturbed Transport and Barrier Properties: Extended Abstracts

    1. Top of page
    2. Frontmatter
    3. Epithelial Transport and Barrier Function: Pathomechanisms in Gastrointestinal Disorders: Part I. Expression of Transporters and Regulation of Ion Transport
    4. Epithelial Transport and Barrier Function: Pathomechanisms in Gastrointestinal Disorders: Part I. Expression of Transporters and Regulation of Ion Transport: Extended Abstracts
    5. Epithelial Transport and Barrier Function: Pathomechanisms in Gastrointestinal Disorders: Part II. Structure and Regulation of the Intestinal Barrier
    6. Epithelial Transport and Barrier Function: Pathomechanisms in Gastrointestinal Disorders: Part III. Models for Studying Disturbed Transport and Barrier Properties
    7. Epithelial Transport and Barrier Function: Pathomechanisms in Gastrointestinal Disorders: Part III. Models for Studying Disturbed Transport and Barrier Properties: Extended Abstracts
    8. Epithelial Transport and Barrier Function: Pathomechanisms in Gastrointestinal Disorders: Part IV. Diarrheal Mechanisms in Gastrointestinal Diseases
    1. Carbachol-Induced Ca2+ Entry into Rat Colonic Epithelium (pages 260–263)

      G. SCHULTHEISS, M. FRINGS and M. DIENER

      Version of Record online: 25 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb05249.x

    2. Effects of Endotoxin on Human Large Intestine (pages 264–266)

      SABINE BÜHNER, BASTIAN MAYR, HAGEN BODE, HEINZ SCHMITZ, JÖRG-DIETER SCHULZKE, MICHAEL FROMM and HERBERT LOCHS

      Version of Record online: 25 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb05250.x

    3. Increased Paracellular Macromolecular Transport and Subnormal Glucose Uptake in Duodenal Biopsies of Patients with Microvillus Inclusion Disease: Comparisons to Other Chronic Diarrhea Patients and to Nondiarrhea Patients (pages 267–269)

      P. B. BIJLSMA, A. J. KILIAAN, G. SCHOLTEN, A. VAN DER WAL, M. HEYMAN, H. S. A. HEYMANS, J. A. GROOT and J. A. J. M. TAMINIAU

      Version of Record online: 25 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb05251.x

    4. Apoptosis and Intestinal Barrier Function (pages 270–274)

      CHRISTIAN BOJARSKI, KERSTIN BENDFELDT, ALFRED H. GITTER, JOACHIM MANKERTZ, MICHAEL FROMM, SIEGFRIED WAGNER, ERNST-OTTO RIECKEN and JÖRG-DIETER SCHULZKE

      Version of Record online: 25 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb05252.x

    5. p53-Independent Apoptosis Induced by Menadione in the Human Colon Carcinoma Cell Line Caco-2 (pages 275–278)

      J. M. KARCZEWSKI, J. A. M. VET, D. HESSELS and J. NOORDHOEK

      Version of Record online: 25 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb05253.x

    6. Epidermal Growth Factor, Polyamines, and Epithelial Remodeling in Caco-2 Cells (pages 279–281)

      VLADAN MILOVIC, RUTH BAUSKE, LYUDMILA TURCHANOWA and JÜRGEN STEIN

      Version of Record online: 25 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb05254.x

    7. Effect of TNFα and IFNγ on Epithelial Barrier Function in Rat Rectum in Vitro (pages 282–286)

      INGO GROTJOHANN, HEINZ SCHMITZ, MICHAEL FROMM and JÖRG-DIETER SCHULZKE

      Version of Record online: 25 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb05255.x

    8. Colectomy and Ileal Pouch: Transport and Barrier in Pouchitis (pages 287–292)

      A. J. KROESEN, M. STOCKMANN, J. D. SCHULZKE, M. FROMM and H. J. BUHR

      Version of Record online: 25 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb05256.x

  7. Epithelial Transport and Barrier Function: Pathomechanisms in Gastrointestinal Disorders: Part IV. Diarrheal Mechanisms in Gastrointestinal Diseases

    1. Top of page
    2. Frontmatter
    3. Epithelial Transport and Barrier Function: Pathomechanisms in Gastrointestinal Disorders: Part I. Expression of Transporters and Regulation of Ion Transport
    4. Epithelial Transport and Barrier Function: Pathomechanisms in Gastrointestinal Disorders: Part I. Expression of Transporters and Regulation of Ion Transport: Extended Abstracts
    5. Epithelial Transport and Barrier Function: Pathomechanisms in Gastrointestinal Disorders: Part II. Structure and Regulation of the Intestinal Barrier
    6. Epithelial Transport and Barrier Function: Pathomechanisms in Gastrointestinal Disorders: Part III. Models for Studying Disturbed Transport and Barrier Properties
    7. Epithelial Transport and Barrier Function: Pathomechanisms in Gastrointestinal Disorders: Part III. Models for Studying Disturbed Transport and Barrier Properties: Extended Abstracts
    8. Epithelial Transport and Barrier Function: Pathomechanisms in Gastrointestinal Disorders: Part IV. Diarrheal Mechanisms in Gastrointestinal Diseases
    1. Mechanisms of Epithelial Barrier Impairment in HIV Infection (pages 293–303)

      MARTIN STOCKMANN, HEINZ SCHMITZ, MICHAEL FROMM, WOLFGANG SCHMIDT, GEORG PAULI, PETER SCHOLZ, ERNST-OTTO RIECKEN and JÖRG-DIETER SCHULZKE

      Version of Record online: 25 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb05257.x

    2. Epithelial Barrier and Transport Function of the Colon in Ulcerative Colitis (pages 312–326)

      H. SCHMITZ, C. BARMEYER, A. H. GITTER, F. WULLSTEIN, C. J. BENTZEL, M. FROMM, E. O. RIECKEN and J. D. SCHULZKE

      Version of Record online: 25 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb05259.x

    3. Diarrhea in Ulcerative Colitis: The Role of Altered Colonic Sodium Transport (pages 327–332)

      EMMA GREIG and GEOFFREY I. SANDLE

      Version of Record online: 25 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb05260.x

    4. Barrier Dysfunction and Crohn's Disease (pages 333–338)

      JON MEDDINGS

      Version of Record online: 25 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb05261.x

    5. Mechanisms of Cholera Toxin-Induced Diarrhea (pages 339–346)

      E. BEUBLER and R. SCHULIGOI

      Version of Record online: 25 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb05262.x

    6. Effects of Clostridium difficile Toxins on Epithelial Cell Barrier (pages 347–356)

      CHARALABOS POTHOULAKIS

      Version of Record online: 25 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb05263.x

    7. Ion Transport during Growth and Differentiation (pages 357–372)

      J. VENKATASUBRAMANIAN, J. SAHI and M. C. RAO

      Version of Record online: 25 JAN 2006 | DOI: 10.1111/j.1749-6632.2000.tb05264.x

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