Annals of the New York Academy of Sciences

Cover image for Annals of the New York Academy of Sciences

April 2002

Volume 959 Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process

Pages xi–xiii, 1–525

  1. Frontmatter

    1. Top of page
    2. Frontmatter
    3. Increasing Healthy Life Span
    4. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part I. Molecular and Cellular Changes with Age
    5. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part II. Exercise and Aging
    6. Article: Part II. Exercise and Aging
    7. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part II. Exercise and Aging
    8. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part III. Nutritional Intervention
    9. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part IV. Antioxidants and Aging
    10. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part V. Pharmacological Intervention in Aging
    11. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part VI. Free Radical Diseases
    12. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part VII. Mitochondrial Changes with Age: Effect on Function
    13. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part VIII. Slowing the Inherent Aging Process
    1. Preface (pages xi–xiii)

      Denham Harman

      Version of Record online: 24 JAN 2006 | DOI: 10.1111/j.1749-6632.2002.tb02076.x

  2. Increasing Healthy Life Span

    1. Top of page
    2. Frontmatter
    3. Increasing Healthy Life Span
    4. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part I. Molecular and Cellular Changes with Age
    5. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part II. Exercise and Aging
    6. Article: Part II. Exercise and Aging
    7. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part II. Exercise and Aging
    8. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part III. Nutritional Intervention
    9. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part IV. Antioxidants and Aging
    10. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part V. Pharmacological Intervention in Aging
    11. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part VI. Free Radical Diseases
    12. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part VII. Mitochondrial Changes with Age: Effect on Function
    13. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part VIII. Slowing the Inherent Aging Process
  3. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part I. Molecular and Cellular Changes with Age

    1. Top of page
    2. Frontmatter
    3. Increasing Healthy Life Span
    4. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part I. Molecular and Cellular Changes with Age
    5. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part II. Exercise and Aging
    6. Article: Part II. Exercise and Aging
    7. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part II. Exercise and Aging
    8. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part III. Nutritional Intervention
    9. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part IV. Antioxidants and Aging
    10. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part V. Pharmacological Intervention in Aging
    11. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part VI. Free Radical Diseases
    12. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part VII. Mitochondrial Changes with Age: Effect on Function
    13. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part VIII. Slowing the Inherent Aging Process
    1. Cell Senescence in Human Aging and Disease (pages 14–23)

      MICHAEL FOSSEL

      Version of Record online: 24 JAN 2006 | DOI: 10.1111/j.1749-6632.2002.tb02078.x

    2. Replicative Aging, Telomeres, and Oxidative Stress (pages 24–29)

      GABRIELE SARETZKI and THOMAS VON ZGLINICKI

      Version of Record online: 24 JAN 2006 | DOI: 10.1111/j.1749-6632.2002.tb02079.x

    3. Down-regulation of Receptor-mediated Endocytosis Is Reponsible for Senescence-associated Hyporesponsiveness (pages 45–49)

      SANG CHUL PARK, JEONG-SOO PARK, WOONG-YANG PARK, KYOUNG-A CHO, JEONG SOO AHN and IK SOON JANG

      Version of Record online: 24 JAN 2006 | DOI: 10.1111/j.1749-6632.2002.tb02081.x

    4. Dietary Restriction Initiated in Late Adulthood Can Reverse Age-related Alterations of Protein and Protein Metabolism (pages 50–56)

      SATARO GOTO, RYOYA TAKAHASHI, SACHIKO ARAKI and HIDEKO NAKAMOTO

      Version of Record online: 24 JAN 2006 | DOI: 10.1111/j.1749-6632.2002.tb02082.x

    5. Pigments in Aging: An Overview (pages 57–65)

      EDUARDO A. PORTA

      Version of Record online: 24 JAN 2006 | DOI: 10.1111/j.1749-6632.2002.tb02083.x

    6. Aging and the Role of Reactive Nitrogen Species (pages 66–81)

      BARRY DREW and CHRISTIAAN LEEUWENBURGH

      Version of Record online: 24 JAN 2006 | DOI: 10.1111/j.1749-6632.2002.tb02084.x

  4. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part II. Exercise and Aging

    1. Top of page
    2. Frontmatter
    3. Increasing Healthy Life Span
    4. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part I. Molecular and Cellular Changes with Age
    5. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part II. Exercise and Aging
    6. Article: Part II. Exercise and Aging
    7. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part II. Exercise and Aging
    8. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part III. Nutritional Intervention
    9. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part IV. Antioxidants and Aging
    10. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part V. Pharmacological Intervention in Aging
    11. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part VI. Free Radical Diseases
    12. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part VII. Mitochondrial Changes with Age: Effect on Function
    13. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part VIII. Slowing the Inherent Aging Process
    1. Exercise-induced Modulation of Antioxidant Defense (pages 82–92)

      LI LI JI

      Version of Record online: 24 JAN 2006 | DOI: 10.1111/j.1749-6632.2002.tb02085.x

    2. The Role of Apoptosis in the Normal Aging Brain, Skeletal Muscle, and Heart (pages 93–107)

      MICHAEL POLLACK, SHARON PHANEUF, AMIE DIRKS and CHRISTIAAN LEEUWENBURGH

      Version of Record online: 24 JAN 2006 | DOI: 10.1111/j.1749-6632.2002.tb02086.x

  5. Article: Part II. Exercise and Aging

    1. Top of page
    2. Frontmatter
    3. Increasing Healthy Life Span
    4. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part I. Molecular and Cellular Changes with Age
    5. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part II. Exercise and Aging
    6. Article: Part II. Exercise and Aging
    7. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part II. Exercise and Aging
    8. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part III. Nutritional Intervention
    9. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part IV. Antioxidants and Aging
    10. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part V. Pharmacological Intervention in Aging
    11. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part VI. Free Radical Diseases
    12. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part VII. Mitochondrial Changes with Age: Effect on Function
    13. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part VIII. Slowing the Inherent Aging Process
  6. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part II. Exercise and Aging

    1. Top of page
    2. Frontmatter
    3. Increasing Healthy Life Span
    4. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part I. Molecular and Cellular Changes with Age
    5. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part II. Exercise and Aging
    6. Article: Part II. Exercise and Aging
    7. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part II. Exercise and Aging
    8. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part III. Nutritional Intervention
    9. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part IV. Antioxidants and Aging
    10. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part V. Pharmacological Intervention in Aging
    11. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part VI. Free Radical Diseases
    12. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part VII. Mitochondrial Changes with Age: Effect on Function
    13. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part VIII. Slowing the Inherent Aging Process
    1. Can Exercise Training Improve Immune Function in the Aged? (pages 117–127)

      JEFFREY A. WOODS, THOMAS W. LOWDER and K. TODD KEYLOCK

      Version of Record online: 24 JAN 2006 | DOI: 10.1111/j.1749-6632.2002.tb02088.x

  7. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part III. Nutritional Intervention

    1. Top of page
    2. Frontmatter
    3. Increasing Healthy Life Span
    4. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part I. Molecular and Cellular Changes with Age
    5. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part II. Exercise and Aging
    6. Article: Part II. Exercise and Aging
    7. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part II. Exercise and Aging
    8. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part III. Nutritional Intervention
    9. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part IV. Antioxidants and Aging
    10. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part V. Pharmacological Intervention in Aging
    11. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part VI. Free Radical Diseases
    12. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part VII. Mitochondrial Changes with Age: Effect on Function
    13. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part VIII. Slowing the Inherent Aging Process
    1. Fruit Polyphenolics and Brain Aging : Nutritional Interventions Targeting Age-related Neuronal and Behavioral Deficits (pages 128–132)

      RACHEL L. GALLI, BARBARA SHUKITT-HALE, KURESH A. YOUDIM and JAMES A. JOSEPH

      Version of Record online: 24 JAN 2006 | DOI: 10.1111/j.1749-6632.2002.tb02089.x

    2. Delaying Brain Mitochondrial Decay and Aging with Mitochondrial Antioxidants and Metabolites (pages 133–166)

      JIANKANG LIU, HANI ATAMNA, HIROHIKO KURATSUNE and BRUCE N. AMES

      Version of Record online: 24 JAN 2006 | DOI: 10.1111/j.1749-6632.2002.tb02090.x

    3. Enhancing Cognitive Function across the Life Span (pages 167–179)

      DONNA L. KOROL

      Version of Record online: 24 JAN 2006 | DOI: 10.1111/j.1749-6632.2002.tb02091.x

    4. Ascorbic Acid, Blood Pressure, and the American Diet (pages 180–187)

      GLADYS BLOCK

      Version of Record online: 24 JAN 2006 | DOI: 10.1111/j.1749-6632.2002.tb02092.x

  8. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part IV. Antioxidants and Aging

    1. Top of page
    2. Frontmatter
    3. Increasing Healthy Life Span
    4. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part I. Molecular and Cellular Changes with Age
    5. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part II. Exercise and Aging
    6. Article: Part II. Exercise and Aging
    7. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part II. Exercise and Aging
    8. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part III. Nutritional Intervention
    9. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part IV. Antioxidants and Aging
    10. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part V. Pharmacological Intervention in Aging
    11. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part VI. Free Radical Diseases
    12. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part VII. Mitochondrial Changes with Age: Effect on Function
    13. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part VIII. Slowing the Inherent Aging Process
    1. Toward Mechanism-based Antioxidant Interventions : Lessons from Natural Antioxidants (pages 188–198)

      VALERIAN E. KAGAN, ELENA R. KISIN, KAZUAKI KAWAI, BEHICE F. SERINKAN, ANATOLY N. OSIPOV, ELENA A. SERBINOVA, IRA WOLINSKY and ANNA A. SHVEDOVA

      Version of Record online: 24 JAN 2006 | DOI: 10.1111/j.1749-6632.2002.tb02093.x

    2. Role of Mitochondria in Oxidative Stress and Aging (pages 199–213)

      GIORGIO LENAZ, CARLA BOVINA, MARILENA D'AURELIO, ROMANA FATO, GABRIELLA FORMIGGINI, MARIA LUISA GENOVA, GIOVANNI GIULIANO, MILENA MERLO PICH, UGO PAOLUCCI, GIOVANNA PARENTI CASTELLI and BARBARA VENTURA

      Version of Record online: 24 JAN 2006 | DOI: 10.1111/j.1749-6632.2002.tb02094.x

    3. Programmed Death Phenomena: From Organelle to Organism (pages 214–237)

      VLADIMIR P. SKULACHEV

      Version of Record online: 24 JAN 2006 | DOI: 10.1111/j.1749-6632.2002.tb02095.x

    4. Melatonin Reduces Oxidant Damage and Promotes Mitochondrial Respiration : Implications for Aging (pages 238–250)

      RUSSEL J. REITER, DUN XIAN TAN, LUCIEN C. MANCHESTER and MAMDOUH R. EL-SAWI

      Version of Record online: 24 JAN 2006 | DOI: 10.1111/j.1749-6632.2002.tb02096.x

    5. Prevention of Mitochondrial Oxidative Damage Using Targeted Antioxidants (pages 263–274)

      GEOFFREY F. KELSO, CAROLYN M. PORTEOUS, GILLIAN HUGHES, ELIZABETH C. LEDGERWOOD, ALISON M. GANE, ROBIN A. J. SMITH and MICHAEL P. MURPHY

      Version of Record online: 24 JAN 2006 | DOI: 10.1111/j.1749-6632.2002.tb02098.x

    6. Cognitive Impairment of Rats Caused by Oxidative Stress and Aging, and Its Prevention by Vitamin E (pages 275–284)

      KOJI FUKUI, NAO-OMI OMOI, TAKAHIRO HAYASAKA, TADASHI SHINNKAI, SHOZO SUZUKI, KOUICHI ABE and SHIRO URANO

      Version of Record online: 24 JAN 2006 | DOI: 10.1111/j.1749-6632.2002.tb02099.x

    7. Reaction of Carnosine with Aged Proteins : Another Protective Process? (pages 285–294)

      ALAN R. HIPKISS, CAROL BROWNSON, MARIANA F. BERTANI, EMILIO RUIZ and ALBERT FERRO

      Version of Record online: 24 JAN 2006 | DOI: 10.1111/j.1749-6632.2002.tb02100.x

  9. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part V. Pharmacological Intervention in Aging

    1. Top of page
    2. Frontmatter
    3. Increasing Healthy Life Span
    4. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part I. Molecular and Cellular Changes with Age
    5. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part II. Exercise and Aging
    6. Article: Part II. Exercise and Aging
    7. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part II. Exercise and Aging
    8. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part III. Nutritional Intervention
    9. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part IV. Antioxidants and Aging
    10. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part V. Pharmacological Intervention in Aging
    11. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part VI. Free Radical Diseases
    12. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part VII. Mitochondrial Changes with Age: Effect on Function
    13. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part VIII. Slowing the Inherent Aging Process
    1. Pharmacological Interventions in Aging and Age-associated Disorders : Potentials of Propargylamines for Human Use (pages 295–307)

      KENICHI KITANI, CHIYOKO MINAMI, TAKAKO YAMAMOTO, SETSUKO KANAI, GWEN O. IVY and MARIA-CRISTINA CARRILLO

      Version of Record online: 24 JAN 2006 | DOI: 10.1111/j.1749-6632.2002.tb02101.x

    2. Nitrones as Neuroprotectants and Antiaging Drugs (pages 321–329)

      ROBERT A. FLOYD, KENNETH HENSLEY, MICHAEL J. FORSTER, JUDITH A. KELLEHER-ANDERSON and PAUL L. WOOD

      Version of Record online: 24 JAN 2006 | DOI: 10.1111/j.1749-6632.2002.tb02103.x

  10. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part VI. Free Radical Diseases

    1. Top of page
    2. Frontmatter
    3. Increasing Healthy Life Span
    4. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part I. Molecular and Cellular Changes with Age
    5. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part II. Exercise and Aging
    6. Article: Part II. Exercise and Aging
    7. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part II. Exercise and Aging
    8. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part III. Nutritional Intervention
    9. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part IV. Antioxidants and Aging
    10. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part V. Pharmacological Intervention in Aging
    11. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part VI. Free Radical Diseases
    12. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part VII. Mitochondrial Changes with Age: Effect on Function
    13. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part VIII. Slowing the Inherent Aging Process
    1. A Unified Mechanism in the Initiation of Cancer (pages 341–354)

      ERCOLE L. CAVALIERI and ELEANOR G. ROGAN

      Version of Record online: 24 JAN 2006 | DOI: 10.1111/j.1749-6632.2002.tb02105.x

    2. Coenzyme Q10 Protects the Aging Heart against Stress : Studies in Rats, Human Tissues, and Patients (pages 355–359)

      FRANKLIN L. ROSENFELDT, SALVATORE PEPE, ANTHONY LINNANE, PHILIP NAGLEY, MICHAEL ROWLAND, RUCHONG OU, SILVANA MARASCO, WILLIAM LYON and DONALD ESMORE

      Version of Record online: 24 JAN 2006 | DOI: 10.1111/j.1749-6632.2002.tb02106.x

    3. The Maillard Hypothesis on Aging: Time to Focus on DNA (pages 360–367)

      JOHN W. BAYNES

      Version of Record online: 24 JAN 2006 | DOI: 10.1111/j.1749-6632.2002.tb02107.x

    4. Oxidative Stress and Programmed Cell Death in Diabetic Neuropathy (pages 368–383)

      ANDREA M. VINCENT, MICHAEL BROWNLEE and JAMES W. RUSSELL

      Version of Record online: 24 JAN 2006 | DOI: 10.1111/j.1749-6632.2002.tb02108.x

    5. Alzheimer's Disease: Role of Aging in Pathogenesis (pages 384–395)

      DENHAM HARMAN

      Version of Record online: 24 JAN 2006 | DOI: 10.1111/j.1749-6632.2002.tb02109.x

  11. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part VII. Mitochondrial Changes with Age: Effect on Function

    1. Top of page
    2. Frontmatter
    3. Increasing Healthy Life Span
    4. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part I. Molecular and Cellular Changes with Age
    5. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part II. Exercise and Aging
    6. Article: Part II. Exercise and Aging
    7. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part II. Exercise and Aging
    8. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part III. Nutritional Intervention
    9. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part IV. Antioxidants and Aging
    10. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part V. Pharmacological Intervention in Aging
    11. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part VI. Free Radical Diseases
    12. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part VII. Mitochondrial Changes with Age: Effect on Function
    13. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part VIII. Slowing the Inherent Aging Process
    1. Human Aging and Global Function of Coenzyme Q10 (pages 396–411)

      ANTHONY W. LINNANE, CHUNFANG ZHANG, NATALIA YAROVAYA, GEORGE KOPSIDAS, SERGEY KOVALENKO, PENNY PAPAKOSTOPOULOS, HAYDEN EASTWOOD, STEPHEN GRAVES and MARTIN RICHARDSON

      Version of Record online: 24 JAN 2006 | DOI: 10.1111/j.1749-6632.2002.tb02110.x

    2. Mitochondrial DNA Deletion Mutations and Sarcopenia (pages 412–423)

      JUDD AIKEN, ENTELA BUA, ZHENGJIN CAO, MARISOL LOPEZ, JON WANAGAT, DEBBIE McKENZIE and SUSAN McKIERNAN

      Version of Record online: 24 JAN 2006 | DOI: 10.1111/j.1749-6632.2002.tb02111.x

    3. Frequent Intracellular Clonal Expansions of Somatic mtDNA Mutations : Significance and Mechanisms (pages 434–447)

      HILARY A. COLLER, NATALYA D. BODYAK and KONSTANTIN KHRAPKO

      Version of Record online: 24 JAN 2006 | DOI: 10.1111/j.1749-6632.2002.tb02113.x

    4. Mitochondrial Damage in Aging and Apoptosis (pages 448–451)

      JUAN SASTRE, CONSUELO BORRÁS, DAVID GARCÍA-SALA, ANA LLORET, FEDERICO V. PALLARDÓ and JOSÉ VIÑA

      Version of Record online: 24 JAN 2006 | DOI: 10.1111/j.1749-6632.2002.tb02114.x

  12. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part VIII. Slowing the Inherent Aging Process

    1. Top of page
    2. Frontmatter
    3. Increasing Healthy Life Span
    4. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part I. Molecular and Cellular Changes with Age
    5. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part II. Exercise and Aging
    6. Article: Part II. Exercise and Aging
    7. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part II. Exercise and Aging
    8. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part III. Nutritional Intervention
    9. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part IV. Antioxidants and Aging
    10. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part V. Pharmacological Intervention in Aging
    11. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part VI. Free Radical Diseases
    12. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part VII. Mitochondrial Changes with Age: Effect on Function
    13. Increasing Healthy Life Span: Conventional Measures and Slowing the Innate Aging Process: Part VIII. Slowing the Inherent Aging Process
    1. Time to Talk SENS: Critiquing the Immutability of Human Aging (pages 452–462)

      AUBREY D. N. J. DE GREY, BRUCE N. AMES, JULIE K. ANDERSEN, ANDRZEJ BARTKE, JUDITH CAMPISI, CHRISTOPHER B. HEWARD, ROGER J. M. McCARTER and GREGORY STOCK

      Version of Record online: 24 JAN 2006 | DOI: 10.1111/j.1749-6632.2002.tb02115.x

    2. Nature of the Aging Process : Open Discussion (pages 463–465)

      AUBREY D. N. J. DE GREY

      Version of Record online: 24 JAN 2006 | DOI: 10.1111/j.1749-6632.2002.tb02116.x

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