Annals of the New York Academy of Sciences

Cover image for Annals of the New York Academy of Sciences

December 2003

Volume 1009 Agmatine and Imidazolines: Their Novel Receptors and Enzymes

Pages xiii–xvi, 1–446

  1. Frontmatter

    1. Top of page
    2. Frontmatter
    3. Agmatine and Imidazolines: Their Novel Receptors and Enzymes: Part I. Agmatine: Basic and Molecular Aspects
    4. Agmatine and Imidazolines: Their Novel Receptors and Enzymes: Part II. Agmatine: Function and Pre-Clinical Aspects
    5. Agmatine and Imidazolines: Their Novel Receptors and Enzymes: Part III. Other Endogenous Ligands for Imidazoline Receptors
    6. Agmatine and Imidazolines: Their Novel Receptors and Enzymes: Part IV. I-1 Imidazoline Receptors
    7. Agmatine and Imidazolines: Their Novel Receptors and Enzymes: Part V. I-2/I-3 Imidazoline Receptors
    8. Agmatine and Imidazolines: Their Novel Receptors and Enzymes: Part VI. IRAS Candidate Imidazoline Receptor
    1. In Memoriam: Donald J. Reis (page xiii)

      Version of Record online: 24 JAN 2006 | DOI: 10.1111/j.1749-6632.2003.tb02471.x

    2. Preface (pages xv–xvi)

      John E. Piletz, Soundar Regunathan and Paul Ernsberger

      Version of Record online: 24 JAN 2006 | DOI: 10.1196/annals.1304.060

  2. Agmatine and Imidazolines: Their Novel Receptors and Enzymes: Part I. Agmatine: Basic and Molecular Aspects

    1. Top of page
    2. Frontmatter
    3. Agmatine and Imidazolines: Their Novel Receptors and Enzymes: Part I. Agmatine: Basic and Molecular Aspects
    4. Agmatine and Imidazolines: Their Novel Receptors and Enzymes: Part II. Agmatine: Function and Pre-Clinical Aspects
    5. Agmatine and Imidazolines: Their Novel Receptors and Enzymes: Part III. Other Endogenous Ligands for Imidazoline Receptors
    6. Agmatine and Imidazolines: Their Novel Receptors and Enzymes: Part IV. I-1 Imidazoline Receptors
    7. Agmatine and Imidazolines: Their Novel Receptors and Enzymes: Part V. I-2/I-3 Imidazoline Receptors
    8. Agmatine and Imidazolines: Their Novel Receptors and Enzymes: Part VI. IRAS Candidate Imidazoline Receptor
    1. Gastrointestinal Uptake of Agmatine: Distribution in Tissues and Organs and Pathophysiologic Relevance (pages 44–51)

      GERHARD J. MOLDERINGS, ANJA HEINEN, SIGRID MENZEL, FRIEDRICH LÜBBECKE, JÜRGEN HOMANN and MANFRED GÖTHERT

      Version of Record online: 24 JAN 2006 | DOI: 10.1196/annals.1304.005

    2. Structure-Activity Analysis of Guanidine Group in Agmatine for Brain Agmatinase (pages 52–63)

      M-J HUANG, S REGUNATHAN, M BOTTA, K LEE, E MCCLENDON, G B YI, M L PEDERSEN, D B BERKOWITZ, G WANG, M TRAVAGLI and J E PILETZ

      Version of Record online: 24 JAN 2006 | DOI: 10.1196/annals.1304.006

    3. Agmatine Crosses the Blood-Brain Barrier (pages 64–74)

      J E. PILETZ, P J. MAY, G WANG and H ZHU

      Version of Record online: 24 JAN 2006 | DOI: 10.1196/annals.1304.007

    4. Identification and Pharmacological Characterization of a Specific Agmatine Transport System in Human Tumor Cell Lines (pages 75–81)

      GERHARD J. MOLDERINGS, MICHAEL BRUSS, HEINZ BONISCH and MANFRED GÖTHERT

      Version of Record online: 24 JAN 2006 | DOI: 10.1196/annals.1304.008

  3. Agmatine and Imidazolines: Their Novel Receptors and Enzymes: Part II. Agmatine: Function and Pre-Clinical Aspects

    1. Top of page
    2. Frontmatter
    3. Agmatine and Imidazolines: Their Novel Receptors and Enzymes: Part I. Agmatine: Basic and Molecular Aspects
    4. Agmatine and Imidazolines: Their Novel Receptors and Enzymes: Part II. Agmatine: Function and Pre-Clinical Aspects
    5. Agmatine and Imidazolines: Their Novel Receptors and Enzymes: Part III. Other Endogenous Ligands for Imidazoline Receptors
    6. Agmatine and Imidazolines: Their Novel Receptors and Enzymes: Part IV. I-1 Imidazoline Receptors
    7. Agmatine and Imidazolines: Their Novel Receptors and Enzymes: Part V. I-2/I-3 Imidazoline Receptors
    8. Agmatine and Imidazolines: Their Novel Receptors and Enzymes: Part VI. IRAS Candidate Imidazoline Receptor
    1. Neuropharmacokinetic and Dynamic Studies of Agmatine (Decarboxylated Arginine) (pages 82–105)

      H OANH X. NGUYEN, CORY J. GORACKE-POSTLE, LORI L. KAMINSKI, AARON C. OVERLAND, ANDREW D. MORGAN and CAROLYN A. FAIRBANKS

      Version of Record online: 24 JAN 2006 | DOI: 10.1196/annals.1304.009

    2. Effect of Agmatine on Acute and Mononeuropathic Pain (pages 106–115)

      FEYZA ARICIOGLU, EYLEM KORCEGEZ, AYHAN BOZKURT and SULEYMAN OZYALCIN

      Version of Record online: 24 JAN 2006 | DOI: 10.1196/annals.1304.010

    3. Is Agmatine an Endogenous Factor Against Stress? (pages 127–132)

      FEYZA ARICIOGLU, SOUNDAR REGUNATHAN and JOHN E. PILETZ

      Version of Record online: 24 JAN 2006 | DOI: 10.1196/annals.1304.012

    4. Agmatine-Morphine Interaction on Nociception in Mice (pages 133–136)

      EDUARDO RUIZ-DURÁNTEZ, JAVIER LLORENTE, ISABEL ULIBARRI, JOSEBA PINEDA and LUISA UGEDO

      Version of Record online: 24 JAN 2006 | DOI: 10.1196/annals.1304.013

    5. Is Agmatine an Endogenous Anxiolytic/Antidepressant Agent? (pages 136–140)

      FEYZA ARICIOGLU and HALE ALTUNBAS

      Version of Record online: 24 JAN 2006 | DOI: 10.1196/annals.1304.014

    6. Effect of Agmatine on Electrically and Chemically Induced Seizures in Mice (pages 141–146)

      FEYZA ARICIOGLU, BILGE KAN, OKAN YILLAR, EYLEM KORCEGEZ and KEMAL BERKMAN

      Version of Record online: 24 JAN 2006 | DOI: 10.1196/annals.1304.015

  4. Agmatine and Imidazolines: Their Novel Receptors and Enzymes: Part III. Other Endogenous Ligands for Imidazoline Receptors

    1. Top of page
    2. Frontmatter
    3. Agmatine and Imidazolines: Their Novel Receptors and Enzymes: Part I. Agmatine: Basic and Molecular Aspects
    4. Agmatine and Imidazolines: Their Novel Receptors and Enzymes: Part II. Agmatine: Function and Pre-Clinical Aspects
    5. Agmatine and Imidazolines: Their Novel Receptors and Enzymes: Part III. Other Endogenous Ligands for Imidazoline Receptors
    6. Agmatine and Imidazolines: Their Novel Receptors and Enzymes: Part IV. I-1 Imidazoline Receptors
    7. Agmatine and Imidazolines: Their Novel Receptors and Enzymes: Part V. I-2/I-3 Imidazoline Receptors
    8. Agmatine and Imidazolines: Their Novel Receptors and Enzymes: Part VI. IRAS Candidate Imidazoline Receptor
    1. Endogenous β-Carbolines as Clonidine-Displacing Substances (pages 157–166)

      ESJ ROBINSON, NJ ANDERSON, J CROSBY, DJ NUTT and AL HUDSON

      Version of Record online: 24 JAN 2006 | DOI: 10.1196/annals.1304.018

    2. Comparative Effects of Efaroxan and b-Carbolines on the Secretory Activity of Rodent and Human b Cells (pages 167–174)

      NOEL G. MORGAN, E JANE COOPER, PAUL E. SQUIRES, CLAIRE E. HILLS, CHRISTINE A. PARKER and ALAN L. HUDSON

      Version of Record online: 24 JAN 2006 | DOI: 10.1196/annals.1304.019

    3. Characterization of [3H]Harmane Binding to Rat Whole Brain Membranes (pages 175–179)

      N J. ANDERSON, ES J. ROBINSON, S M. HUSBANDS, P DELAGRANGE, D J. NUTT and A L. HUDSON

      Version of Record online: 24 JAN 2006 | DOI: 10.1196/annals.1304.020

    4. Effect of Harmane on Mononeuropathic Pain in Rats (pages 180–184)

      FEYZA ARICIOGLU, EYLEM KORCEGEZ and SULEYMAN OZYALCIN

      Version of Record online: 24 JAN 2006 | DOI: 10.1196/annals.1304.021

    5. Inhibitory Effect of Harmane on Morphine-Dependent Guinea Pig Ileum (pages 185–189)

      FEYZA ARICIOGLU and TIJEN UTKAN

      Version of Record online: 24 JAN 2006 | DOI: 10.1196/annals.1304.022

    6. Effect of Harmane on the Convulsive Threshold in Epilepsy Models in Mice (pages 190–195)

      FEYZA ARICIOGLU, OKAN YILLAR, EYLEM KORCEGEZ and KEMAL BERKMAN

      Version of Record online: 24 JAN 2006 | DOI: 10.1196/annals.1304.023

    7. Harmane Induces Anxiolysis and Antidepressant-Like Effects in Rats (pages 196–201)

      FEYZA ARICIOGLU and HALE ALTUNBAS

      Version of Record online: 24 JAN 2006 | DOI: 10.1196/annals.1304.024

    8. Endogenous Imidazoline Receptor Ligands Relax Rat Aorta by an Endothelium-Dependent Mechanism (pages 222–227)

      IAN F. MUSGRAVE, ANDREA VAN DER ZYPP, MATHEW GRIGG and COLIN J. BARROW

      Version of Record online: 24 JAN 2006 | DOI: 10.1196/annals.1304.027

  5. Agmatine and Imidazolines: Their Novel Receptors and Enzymes: Part IV. I-1 Imidazoline Receptors

    1. Top of page
    2. Frontmatter
    3. Agmatine and Imidazolines: Their Novel Receptors and Enzymes: Part I. Agmatine: Basic and Molecular Aspects
    4. Agmatine and Imidazolines: Their Novel Receptors and Enzymes: Part II. Agmatine: Function and Pre-Clinical Aspects
    5. Agmatine and Imidazolines: Their Novel Receptors and Enzymes: Part III. Other Endogenous Ligands for Imidazoline Receptors
    6. Agmatine and Imidazolines: Their Novel Receptors and Enzymes: Part IV. I-1 Imidazoline Receptors
    7. Agmatine and Imidazolines: Their Novel Receptors and Enzymes: Part V. I-2/I-3 Imidazoline Receptors
    8. Agmatine and Imidazolines: Their Novel Receptors and Enzymes: Part VI. IRAS Candidate Imidazoline Receptor
    1. I1 Imidazoline Receptors Involved in Cardiovascular Regulation: Where Are We and Where Are We Going? (pages 228–233)

      P BOUSQUET, H GRENEY, V BRUBAN, S SCHANN, JD EHRHARDT, L MONASSIER and J FELDMAN

      Version of Record online: 24 JAN 2006 | DOI: 10.1196/annals.1304.028

    2. Cardiac Effects of Moxonidine in Spontaneously Hypertensive Obese Rats (pages 244–250)

      S MUKADDAM-DAHER, A MENAOUAR, R EL-AYOUBI, J GUTKOWSKA, M JANKOWSKI, RA VELLIQUETTE and P ERNSBERGER

      Version of Record online: 24 JAN 2006 | DOI: 10.1196/annals.1304.030

    3. Involvement of Forebrain Imidazoline and a2-Adrenergic Receptors in the Antidipsogenic Response to Moxonidine (pages 262–264)

      CARINA A.F. ANDRADE, LISANDRA B. OLIVEIRA, GIZELE MARTINEZ, DANIELA C.F. SILVA, LAURIVAL A. DE LUCA JR. and JOSÉ V. MENANI

      Version of Record online: 24 JAN 2006 | DOI: 10.1196/annals.1304.032

    4. Moxonidine Displays a Presynaptic Alpha-2-Adrenoceptor-Dependent Synergistic Sympathoinhibitory Action at Imidazoline-1 Receptors (pages 265–269)

      ULRICH SCHÄFER, CHRISTOF BURGDORF, ASTRID ENGELHARDT, WALTER RAASCH, THOMAS KURZ and GERT RICHARDT

      Version of Record online: 24 JAN 2006 | DOI: 10.1196/annals.1304.033

    5. Norepinephrine Release Is Reduced by I1-Receptors in Addition to a2-Adrenoceptors (pages 270–273)

      WALTER RAASCH, BRITTA JUNGBLUTH, ULRICH SCHÄFER, WALTER HÄUSER and PETER DOMINIAK

      Version of Record online: 24 JAN 2006 | DOI: 10.1196/annals.1304.034

    6. BU98008, a Highly Selective Imidazoline1-Receptor Ligand (pages 283–287)

      ESJ ROBINSON, RE PRICE, DJ NUTT and AL HUDSON

      Version of Record online: 24 JAN 2006 | DOI: 10.1196/annals.1304.037

    7. Apparent Absence of Direct Renal Effect of Imidazoline Receptor Agonists (pages 288–295)

      DD SMYTH, D PIRNAT, B FORZLEY and SB PENNER

      Version of Record online: 24 JAN 2006 | DOI: 10.1196/annals.1304.059

  6. Agmatine and Imidazolines: Their Novel Receptors and Enzymes: Part V. I-2/I-3 Imidazoline Receptors

    1. Top of page
    2. Frontmatter
    3. Agmatine and Imidazolines: Their Novel Receptors and Enzymes: Part I. Agmatine: Basic and Molecular Aspects
    4. Agmatine and Imidazolines: Their Novel Receptors and Enzymes: Part II. Agmatine: Function and Pre-Clinical Aspects
    5. Agmatine and Imidazolines: Their Novel Receptors and Enzymes: Part III. Other Endogenous Ligands for Imidazoline Receptors
    6. Agmatine and Imidazolines: Their Novel Receptors and Enzymes: Part IV. I-1 Imidazoline Receptors
    7. Agmatine and Imidazolines: Their Novel Receptors and Enzymes: Part V. I-2/I-3 Imidazoline Receptors
    8. Agmatine and Imidazolines: Their Novel Receptors and Enzymes: Part VI. IRAS Candidate Imidazoline Receptor
    1. Novel Ligands for the Investigation of Imidazoline Receptors and Their Binding Proteins (pages 302–308)

      AL HUDSON, RJ TYACKE, MD LALIES, N DAVIES, DP FINN, O MARTÍ, E ROBINSON, S HUSBANDS, MCW MINCHIN, A KIMURA and DJ NUTT

      Version of Record online: 24 JAN 2006 | DOI: 10.1196/annals.1304.039

    2. Relationship Between Imidazoline2 Sites and Monoamine Oxidase (pages 353–356)

      LM PATERSON, RJ TYACKE, DJ NUTT and AL HUDSON

      Version of Record online: 24 JAN 2006 | DOI: 10.1196/annals.1304.045

    3. Initial Evaluation of Novel Selective Ligands for Imidazoline2 Receptors in Rat Whole Brain (pages 357–360)

      RJ TYACKE, F SAZCZEWSKI, P TABIN, J SAZCZEWSKI, DJ NUTT and AL HUDSON

      Version of Record online: 24 JAN 2006 | DOI: 10.1196/annals.1304.046

    4. Investigation of the Affinities of Two New b-Carbolines for Rat Brain Imidazoline2 Receptors (pages 361–363)

      RJ TYACKE, A LAU, B GRELLA, RA GLENNON, DJ NUTT and AL HUDSON

      Version of Record online: 24 JAN 2006 | DOI: 10.1196/annals.1304.047

    5. Identification of an I2 Binding Protein From Rabbit Brain (pages 364–366)

      A KIMURA, RJ TYACKE, MCW MINCHIN, DJ NUTT and AL HUDSON

      Version of Record online: 24 JAN 2006 | DOI: 10.1196/annals.1304.048

    6. In Vivo Estimation of Imidazoline2 Binding Site Turnover (pages 367–370)

      LM PATERSON, ESJ ROBINSON, DJ NUTT and AL HUDSON

      Version of Record online: 24 JAN 2006 | DOI: 10.1196/annals.1304.049

  7. Agmatine and Imidazolines: Their Novel Receptors and Enzymes: Part VI. IRAS Candidate Imidazoline Receptor

    1. Top of page
    2. Frontmatter
    3. Agmatine and Imidazolines: Their Novel Receptors and Enzymes: Part I. Agmatine: Basic and Molecular Aspects
    4. Agmatine and Imidazolines: Their Novel Receptors and Enzymes: Part II. Agmatine: Function and Pre-Clinical Aspects
    5. Agmatine and Imidazolines: Their Novel Receptors and Enzymes: Part III. Other Endogenous Ligands for Imidazoline Receptors
    6. Agmatine and Imidazolines: Their Novel Receptors and Enzymes: Part IV. I-1 Imidazoline Receptors
    7. Agmatine and Imidazolines: Their Novel Receptors and Enzymes: Part V. I-2/I-3 Imidazoline Receptors
    8. Agmatine and Imidazolines: Their Novel Receptors and Enzymes: Part VI. IRAS Candidate Imidazoline Receptor
    1. Evidence for Nonadrenoceptor Responses to Imidazoline Derivatives in the Porcine Isolated Rectal Artery (pages 386–391)

      MINYAN WANG, WR DUNN, SL CHAN, B GARFIELD and VG WILSON

      Version of Record online: 24 JAN 2006 | DOI: 10.1196/annals.1304.052

    2. IRAS Is an Anti-Apoptotic Protein (pages 400–412)

      MONIQUE DONTENWILL, JOHN E. PILETZ, MICHAEL CHEN, JAMES BALDWIN, GÉRALDINE PASCAL, PHILIPPE RONDÉ, LAURENCE DUPUY, HUGUES GRENEY, KEN TAKEDA and PASCAL BOUSQUETD

      Version of Record online: 24 JAN 2006 | DOI: 10.1196/annals.1304.054

    3. IRAS Splice Variants (pages 419–426)

      JE PILETZ, W DELEERSNIJDER, BL ROTH, P ERNSBERGER, H ZHU and D ZIEGLER

      Version of Record online: 24 JAN 2006 | DOI: 10.1196/annals.1304.056

    4. Intracellular Effect of Imidazoline Receptor on α2A-Noradrenergic Receptor (pages 427–438)

      MICHAEL J. CHEN, HE ZHU and JOHN E. PILETZ

      Version of Record online: 24 JAN 2006 | DOI: 10.1196/annals.1304.057

    5. Relationship between Platelet Imidazoline Receptor-Binding Peptides and Candidate Imidazoline-1 Receptor, IRAS (pages 439–446)

      HE ZHU, JONATHAN HAYES, MICHAEL CHEN, JAMES BALDWIN and JOHN E. PILETZ

      Version of Record online: 24 JAN 2006 | DOI: 10.1196/annals.1304.058

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