Annals of the New York Academy of Sciences

Cover image for Annals of the New York Academy of Sciences

May 2004

Volume 1015 Cardiac Engineering: From Genes and Cells to Structure and Function

Pages xi–xviii, 1–404

  1. Frontmatter

    1. Top of page
    2. Frontmatter
    3. Cardiac Engineering: From Genes and Cells to Structure and Function: Part I. Excitation and Contraction Coupling
    4. Cardiac Engineering: From Genes and Cells to Structure and Function: Part II. Molecular and Cellular Electrocardiology
    5. Part II. Molecular and Cellular Electrocardiology
    6. Cardiac Engineering: From Genes and Cells to Structure and Function: Part III. Cardiac Development
    7. Cardiac Engineering: From Genes and Cells to Structure and Function: Part IV. Genes and Function
    8. Cardiac Engineering: From Genes and Cells to Structure and Function: Part V. Cellular and Tissue Engineering
    9. Cardiac Engineering: From Genes and Cells to Structure and Function: Part VI. Novel Therapeutic Modalities
    10. Epilogue
  2. Cardiac Engineering: From Genes and Cells to Structure and Function: Part I. Excitation and Contraction Coupling

    1. Top of page
    2. Frontmatter
    3. Cardiac Engineering: From Genes and Cells to Structure and Function: Part I. Excitation and Contraction Coupling
    4. Cardiac Engineering: From Genes and Cells to Structure and Function: Part II. Molecular and Cellular Electrocardiology
    5. Part II. Molecular and Cellular Electrocardiology
    6. Cardiac Engineering: From Genes and Cells to Structure and Function: Part III. Cardiac Development
    7. Cardiac Engineering: From Genes and Cells to Structure and Function: Part IV. Genes and Function
    8. Cardiac Engineering: From Genes and Cells to Structure and Function: Part V. Cellular and Tissue Engineering
    9. Cardiac Engineering: From Genes and Cells to Structure and Function: Part VI. Novel Therapeutic Modalities
    10. Epilogue
    1. Modeling the Actions of β-Adrenergic Signaling on Excitation—Contraction Coupling Processes (pages 16–27)

      JOSEPH L. GREENSTEIN, ANTTI J. TANSKANEN and RAIMOND L. WINSLOW

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1302.002

    2. Integrated Ca2+ Management in Cardiac Myocytes (pages 28–38)

      THOMAS R. SHANNON and DONALD M. BERS

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1302.003

    3. Molecular and Integrated Biology of Thin Filament Protein Phosphorylation in Heart Muscle (pages 39–52)

      MARIUS P. SUMANDEA, EILEEN M. BURKART, TOMOYOSHI KOBAYASHI, PIETER P. DE TOMBE and R JOHN SOLARO

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1302.004

    4. Mechanotransduction in Cardiac Myocytes (pages 53–70)

      JAN LAMMERDING, ROGER D. KAMM and RICHARD T. LEE

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1302.005

    5. The Adaptive Intracellular Control of Cardiac Muscle Function (pages 71–83)

      AMIR LANDESBERG, CARMIT LEVY, YAEL YANIV and SAMUEL SIDEMAN

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1302.006

    6. Congestive Heart Failure after Myocardial Infarction in the Rat: Cardiac Force and Spontaneous Sarcomere Activity (pages 84–95)

      A W DAVIDOFF, P A BOYDEN, K SCHWARTZ, J B MICHEL, Y M ZHANG, M OBAYASHI, D CRABBE and H E D J TER KEURS

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1302.007

  3. Cardiac Engineering: From Genes and Cells to Structure and Function: Part II. Molecular and Cellular Electrocardiology

    1. Top of page
    2. Frontmatter
    3. Cardiac Engineering: From Genes and Cells to Structure and Function: Part I. Excitation and Contraction Coupling
    4. Cardiac Engineering: From Genes and Cells to Structure and Function: Part II. Molecular and Cellular Electrocardiology
    5. Part II. Molecular and Cellular Electrocardiology
    6. Cardiac Engineering: From Genes and Cells to Structure and Function: Part III. Cardiac Development
    7. Cardiac Engineering: From Genes and Cells to Structure and Function: Part IV. Genes and Function
    8. Cardiac Engineering: From Genes and Cells to Structure and Function: Part V. Cellular and Tissue Engineering
    9. Cardiac Engineering: From Genes and Cells to Structure and Function: Part VI. Novel Therapeutic Modalities
    10. Epilogue
    1. Genetics of Cardiac Arrhythmias and Sudden Cardiac Death (pages 96–110)

      SILVIA G. PRIORI and CARLO NAPOLITANO

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1302.008

    2. Pacemaker Channels (pages 111–121)

      MIRKO BARUSCOTTI and DARIO DIFRANCESCO

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1302.009

    3. Ventricular Fibrillation: New Insights into Mechanisms (pages 122–132)

      JAMES N. WEISS, PENG-SHENG CHEN, TSU-JUEY WU, CARIN SIEGERMAN and ALAN GARFINKEL

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1302.010

  4. Part II. Molecular and Cellular Electrocardiology

    1. Top of page
    2. Frontmatter
    3. Cardiac Engineering: From Genes and Cells to Structure and Function: Part I. Excitation and Contraction Coupling
    4. Cardiac Engineering: From Genes and Cells to Structure and Function: Part II. Molecular and Cellular Electrocardiology
    5. Part II. Molecular and Cellular Electrocardiology
    6. Cardiac Engineering: From Genes and Cells to Structure and Function: Part III. Cardiac Development
    7. Cardiac Engineering: From Genes and Cells to Structure and Function: Part IV. Genes and Function
    8. Cardiac Engineering: From Genes and Cells to Structure and Function: Part V. Cellular and Tissue Engineering
    9. Cardiac Engineering: From Genes and Cells to Structure and Function: Part VI. Novel Therapeutic Modalities
    10. Epilogue
    1. Cardiac Ryanodine Receptor Function and Regulation in Heart Disease (pages 144–159)

      STEPHAN E. LEHNART, XANDER H. T. WEHRENS, ALEXANDER KUSHNIR and ANDREW R. MARKS

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1302.012

  5. Cardiac Engineering: From Genes and Cells to Structure and Function: Part III. Cardiac Development

    1. Top of page
    2. Frontmatter
    3. Cardiac Engineering: From Genes and Cells to Structure and Function: Part I. Excitation and Contraction Coupling
    4. Cardiac Engineering: From Genes and Cells to Structure and Function: Part II. Molecular and Cellular Electrocardiology
    5. Part II. Molecular and Cellular Electrocardiology
    6. Cardiac Engineering: From Genes and Cells to Structure and Function: Part III. Cardiac Development
    7. Cardiac Engineering: From Genes and Cells to Structure and Function: Part IV. Genes and Function
    8. Cardiac Engineering: From Genes and Cells to Structure and Function: Part V. Cellular and Tissue Engineering
    9. Cardiac Engineering: From Genes and Cells to Structure and Function: Part VI. Novel Therapeutic Modalities
    10. Epilogue
    1. Development of the Building Plan of the Heart (pages 171–181)

      ANTOON F. M. MOORMAN, ALEXANDRE T. SOUFAN, JACO HAGOORT, PIET A. J. DE BOER and VINCENT M. CHRISTOFFELS

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1302.014

    2. Cardiac Muscle Plasticity in Adult and Embryo by Heart-Derived Progenitor Cells (pages 182–189)

      HIDEMASA OH, XUAN CHI, STEVEN B. BRADFUTE, YUJI MISHINA, JENNIFER POCIUS, LLOYD H. MICHAEL, RICHARD R. BEHRINGER, ROBERT J. SCHWARTZ, MARK L. ENTMAN and MICHAEL D. SCHNEIDER

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1302.015

    3. Cardiac Fiber Orientation and the Left-Right Asymmetry Determining Mechanism (pages 190–201)

      TAMMO DELHAAS, WIM DECALUWE, MIRJAM RUBBENS, ROY KERCKHOFFS and THEO ARTS

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1302.016

  6. Cardiac Engineering: From Genes and Cells to Structure and Function: Part IV. Genes and Function

    1. Top of page
    2. Frontmatter
    3. Cardiac Engineering: From Genes and Cells to Structure and Function: Part I. Excitation and Contraction Coupling
    4. Cardiac Engineering: From Genes and Cells to Structure and Function: Part II. Molecular and Cellular Electrocardiology
    5. Part II. Molecular and Cellular Electrocardiology
    6. Cardiac Engineering: From Genes and Cells to Structure and Function: Part III. Cardiac Development
    7. Cardiac Engineering: From Genes and Cells to Structure and Function: Part IV. Genes and Function
    8. Cardiac Engineering: From Genes and Cells to Structure and Function: Part V. Cellular and Tissue Engineering
    9. Cardiac Engineering: From Genes and Cells to Structure and Function: Part VI. Novel Therapeutic Modalities
    10. Epilogue
    1. Linking Gene Expression to Function: Metabolic Flexibility in the Normal and Diseased Heart (pages 202–213)

      HEINRICH TAEGTMEYER, LEONARD GOLFMAN, SAUMYA SHARMA, PETER RAZEGHI and MELISSA VAN ARSDALL

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1302.017

    2. Molecular and Cellular Aspects of Troponin Cardiomyopathies (pages 214–224)

      ALDRIN V. GOMES and JAMES D. POTTER

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1302.018

    3. Genetic Factors in Cardiac Hypertrophy (pages 225–237)

      GERALD W. DORN II and HARVEY S. HAHN

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1302.019

    4. “Energenetics” of Heart Failure (pages 238–249)

      MARC VAN BILSEN

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1302.020

    5. Regulation of Cell Size and Contractile Function by AKT in Cardiomyocytes (pages 250–260)

      MICHAEL V. G. LATRONICO, STEFAN COSTINEAN, MARIA LUISA LAVITRANO, CESARE PESCHLE and GIANLUIGI CONDORELLI

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1302.021

  7. Cardiac Engineering: From Genes and Cells to Structure and Function: Part V. Cellular and Tissue Engineering

    1. Top of page
    2. Frontmatter
    3. Cardiac Engineering: From Genes and Cells to Structure and Function: Part I. Excitation and Contraction Coupling
    4. Cardiac Engineering: From Genes and Cells to Structure and Function: Part II. Molecular and Cellular Electrocardiology
    5. Part II. Molecular and Cellular Electrocardiology
    6. Cardiac Engineering: From Genes and Cells to Structure and Function: Part III. Cardiac Development
    7. Cardiac Engineering: From Genes and Cells to Structure and Function: Part IV. Genes and Function
    8. Cardiac Engineering: From Genes and Cells to Structure and Function: Part V. Cellular and Tissue Engineering
    9. Cardiac Engineering: From Genes and Cells to Structure and Function: Part VI. Novel Therapeutic Modalities
    10. Epilogue
    1. Genetically Engineered Stem Cell Therapy for Tissue Regeneration (pages 271–284)

      GIULIO ALESSANDRI, COSTANZA EMANUELI and PAOLO MADEDDU

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1302.023

    2. Controlling the Cellular Organization of Tissue-Engineered Cardiac Constructs (pages 299–311)

      MAYA GONEN-WADMANY, LIOR GEPSTEIN and DROR SELIKTAR

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1302.025

  8. Cardiac Engineering: From Genes and Cells to Structure and Function: Part VI. Novel Therapeutic Modalities

    1. Top of page
    2. Frontmatter
    3. Cardiac Engineering: From Genes and Cells to Structure and Function: Part I. Excitation and Contraction Coupling
    4. Cardiac Engineering: From Genes and Cells to Structure and Function: Part II. Molecular and Cellular Electrocardiology
    5. Part II. Molecular and Cellular Electrocardiology
    6. Cardiac Engineering: From Genes and Cells to Structure and Function: Part III. Cardiac Development
    7. Cardiac Engineering: From Genes and Cells to Structure and Function: Part IV. Genes and Function
    8. Cardiac Engineering: From Genes and Cells to Structure and Function: Part V. Cellular and Tissue Engineering
    9. Cardiac Engineering: From Genes and Cells to Structure and Function: Part VI. Novel Therapeutic Modalities
    10. Epilogue
    1. Gene Therapy for Cardiac Arrhythmias (pages 332–337)

      J KEVIN DONAHUE

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1302.029

    2. The Fas Receptor—1,4,5-IP3 Cascade: A Potential Target for Treating Heart Failure and Arrhythmias (pages 338–350)

      OFER BINAH, MARK SHILKRUT, GAL YANIV and SARIT LARISCH

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1302.030

    3. Novel Approaches to Reduce Restenosis (pages 367–378)

      RAFAEL BEYAR

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1302.032

    4. Augmentation of Dilated Failing Left Ventricular Stroke Work by a Physiological Cardiac Assist Device (pages 379–390)

      AMIR LANDESBERG, EUGENE KONYUKHOV, RONA SHOFTI, YUVAL VAKNIN, AVSHALOM SHENHAV, LEONID LIVSHITZ, OSCAR LICHTENSTEIN, CARMIT LEVY, RAFAEL BEYAR, SAMUEL SIDEMAN, OHANA ISRAEL, HENK E. D. J. TER KEURS and GIORA LANDESBERG

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1302.033

  9. Epilogue

    1. Top of page
    2. Frontmatter
    3. Cardiac Engineering: From Genes and Cells to Structure and Function: Part I. Excitation and Contraction Coupling
    4. Cardiac Engineering: From Genes and Cells to Structure and Function: Part II. Molecular and Cellular Electrocardiology
    5. Part II. Molecular and Cellular Electrocardiology
    6. Cardiac Engineering: From Genes and Cells to Structure and Function: Part III. Cardiac Development
    7. Cardiac Engineering: From Genes and Cells to Structure and Function: Part IV. Genes and Function
    8. Cardiac Engineering: From Genes and Cells to Structure and Function: Part V. Cellular and Tissue Engineering
    9. Cardiac Engineering: From Genes and Cells to Structure and Function: Part VI. Novel Therapeutic Modalities
    10. Epilogue
    1. The Computational Integrated Myocyte: A View into the Virtual Heart (pages 391–404)

      JAMES B. BASSINGTHWAIGHTE and KALYAN C. VINNAKOTA

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1302.034

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