Annals of the New York Academy of Sciences

Cover image for Vol. 1025 Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity

October 2004

Volume 1025 Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity

Pages xiii–xiv, 1–637

  1. Frontmatter

    1. Top of page
    2. Frontmatter
    3. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part I. Molecular Genetics of Substance Abuse-Related Disorders
    4. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part II. Molecular Genetics of Psychostimulant Dependence and Toxicity: Gene Expression and Animal Models
    5. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part III. Knockout/Transgenic Approaches to Psychostimulant-Induced Neurotoxicity
    6. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part IV. Neurodegeneration, Neuroprotection in Substituted Amphetamine-Induced Neurotoxicity
    7. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part V. Biological Markers and Molecular Mechanisms of Methamphetamine Psychosis
    8. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part VI. Molecular and Neural Mechanisms of Cocaine: Dopamine Hypothesis
    9. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part VII. Cellular and Molecular Bases of Opioid Dependence
    10. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part VIII. Japanese Forum on Nicotine and Drug Dependence Studies
    11. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part IX. Nicotine and Marijuana
    12. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part X. Organic Solvent and Miscellaneous
    13. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part XI. Approaches to Pharmacotherapy for Drug Dependence
    14. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part XII. Perinatal Exposure of Nicotine, Cocaine, Amphetamines, and Heroin: Neurobehavioral and Neurochemical Outcomes
    1. Preface (pages xiii–xiv)

      SYED F. ALI, TOSHITAKA NABESHIMA and TOMOJI YANAGITA

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1316.080

  2. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part I. Molecular Genetics of Substance Abuse-Related Disorders

    1. Top of page
    2. Frontmatter
    3. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part I. Molecular Genetics of Substance Abuse-Related Disorders
    4. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part II. Molecular Genetics of Psychostimulant Dependence and Toxicity: Gene Expression and Animal Models
    5. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part III. Knockout/Transgenic Approaches to Psychostimulant-Induced Neurotoxicity
    6. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part IV. Neurodegeneration, Neuroprotection in Substituted Amphetamine-Induced Neurotoxicity
    7. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part V. Biological Markers and Molecular Mechanisms of Methamphetamine Psychosis
    8. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part VI. Molecular and Neural Mechanisms of Cocaine: Dopamine Hypothesis
    9. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part VII. Cellular and Molecular Bases of Opioid Dependence
    10. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part VIII. Japanese Forum on Nicotine and Drug Dependence Studies
    11. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part IX. Nicotine and Marijuana
    12. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part X. Organic Solvent and Miscellaneous
    13. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part XI. Approaches to Pharmacotherapy for Drug Dependence
    14. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part XII. Perinatal Exposure of Nicotine, Cocaine, Amphetamines, and Heroin: Neurobehavioral and Neurochemical Outcomes
    1. The Application of Proteomics to the Human Alcoholic Brain (pages 14–26)

      JOANNE M. LEWOHL, DEREK D. VAN DYK, GEORGE E. CRAFT, DAVID J. INNES, R DAYNE MAYFIELD, GARY COBON, R ADRON HARRIS and PETER R. DODD

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1316.002

    2. Association Studies of Neurotransmitter Gene Polymorphisms in Alcoholic Caucasians (pages 39–46)

      P F FOLEY, E W LOH, D J INNES, S M WILLIAMS, A E G TANNENBERG, C G HARPER and P R DODD

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1316.005

  3. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part II. Molecular Genetics of Psychostimulant Dependence and Toxicity: Gene Expression and Animal Models

    1. Top of page
    2. Frontmatter
    3. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part I. Molecular Genetics of Substance Abuse-Related Disorders
    4. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part II. Molecular Genetics of Psychostimulant Dependence and Toxicity: Gene Expression and Animal Models
    5. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part III. Knockout/Transgenic Approaches to Psychostimulant-Induced Neurotoxicity
    6. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part IV. Neurodegeneration, Neuroprotection in Substituted Amphetamine-Induced Neurotoxicity
    7. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part V. Biological Markers and Molecular Mechanisms of Methamphetamine Psychosis
    8. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part VI. Molecular and Neural Mechanisms of Cocaine: Dopamine Hypothesis
    9. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part VII. Cellular and Molecular Bases of Opioid Dependence
    10. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part VIII. Japanese Forum on Nicotine and Drug Dependence Studies
    11. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part IX. Nicotine and Marijuana
    12. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part X. Organic Solvent and Miscellaneous
    13. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part XI. Approaches to Pharmacotherapy for Drug Dependence
    14. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part XII. Perinatal Exposure of Nicotine, Cocaine, Amphetamines, and Heroin: Neurobehavioral and Neurochemical Outcomes
    1. Molecular Mechanisms Underlying the Rewarding Effects of Cocaine (pages 47–56)

      F SCOTT HALL, ICHIRO SORA, JANA DRGONOVA, XIAO-FEI LI, MICHELLE GOEB and GEORGE R. UHL

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1316.006

    2. Specific Gene Expression and Possible Involvement of Inflammation in Methamphetamine-Induced Neurotoxicity (pages 69–75)

      MASATO ASANUMA, IKUKO MIYAZAKI, YOUICHIROU HIGASHI, TAKESHI TSUJI and NORIO OGAWA

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1316.009

    3. Prefrontal Abnormality of Schizophrenia Revealed by DNA Microarray: Impact on Glial and Neurotrophic Gene Expression (pages 84–91)

      TETSUJI SUGAI, MEIKO KAWAMURA, SHUJI IRITANI, KAZUAKI ARAKI, TAKAO MAKIFUCHI, CHINA IMAI, RYOSUKE NAKAMURA, AKIYOSHI KAKITA, HITOSHI TAKAHASHI and HIROYUKI NAWA

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1316.011

    4. Changes in Expression of the Mouse Homologues of KIAA Genes after Subchronic Methamphetamine Treatment (pages 92–101)

      H YAMAMOTO, K IMAI, Y TAKAMATSU, E KAMEGAYA, Y HARA, K SHIMADA, T YAMAMOTO, H-W SHEN, Y HAGINO, H KOBAYASHI, S IDE, I SORA, H KOGA and K IKEDAA

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1316.012

    5. Psychostimulant Alters Expression of DNA Methyltransferase mRNA in the Rat Brain (pages 102–109)

      YOHTARO NUMACHI, SUMIKO YOSHIDA, MOTOYASU YAMASHITA, KO FUJIYAMA, MAKI NAKA, HIROO MATSUOKA, MITSUMOTO SATO and ICHIRO SORA

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1316.013

  4. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part III. Knockout/Transgenic Approaches to Psychostimulant-Induced Neurotoxicity

    1. Top of page
    2. Frontmatter
    3. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part I. Molecular Genetics of Substance Abuse-Related Disorders
    4. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part II. Molecular Genetics of Psychostimulant Dependence and Toxicity: Gene Expression and Animal Models
    5. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part III. Knockout/Transgenic Approaches to Psychostimulant-Induced Neurotoxicity
    6. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part IV. Neurodegeneration, Neuroprotection in Substituted Amphetamine-Induced Neurotoxicity
    7. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part V. Biological Markers and Molecular Mechanisms of Methamphetamine Psychosis
    8. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part VI. Molecular and Neural Mechanisms of Cocaine: Dopamine Hypothesis
    9. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part VII. Cellular and Molecular Bases of Opioid Dependence
    10. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part VIII. Japanese Forum on Nicotine and Drug Dependence Studies
    11. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part IX. Nicotine and Marijuana
    12. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part X. Organic Solvent and Miscellaneous
    13. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part XI. Approaches to Pharmacotherapy for Drug Dependence
    14. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part XII. Perinatal Exposure of Nicotine, Cocaine, Amphetamines, and Heroin: Neurobehavioral and Neurochemical Outcomes
    1. Methamphetamine and Brain Histamine: A Study Using Histamine-Related Gene Knockout Mice (pages 129–134)

      KENTARO IWABUCHI, YASUHIKO KUBOTA, CHIHIRO ITO, TAKESHI WATANABE, TAKEHIKO WATANABE and KAZUHIKO YANAI

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1316.016

    2. Nootropic Nefiracetam Inhibits Proconvulsant Action of Peripheral-Type Benzodiazepines in Epileptic Mutant EL Mice (pages 135–139)

      YURIE NAKAMOTO, TADASHI SHIOTANI, SHIGEO WATABE, TOSHITAKA NABESHIMA and MITSUNOBU YOSHII

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1316.017

  5. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part IV. Neurodegeneration, Neuroprotection in Substituted Amphetamine-Induced Neurotoxicity

    1. Top of page
    2. Frontmatter
    3. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part I. Molecular Genetics of Substance Abuse-Related Disorders
    4. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part II. Molecular Genetics of Psychostimulant Dependence and Toxicity: Gene Expression and Animal Models
    5. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part III. Knockout/Transgenic Approaches to Psychostimulant-Induced Neurotoxicity
    6. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part IV. Neurodegeneration, Neuroprotection in Substituted Amphetamine-Induced Neurotoxicity
    7. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part V. Biological Markers and Molecular Mechanisms of Methamphetamine Psychosis
    8. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part VI. Molecular and Neural Mechanisms of Cocaine: Dopamine Hypothesis
    9. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part VII. Cellular and Molecular Bases of Opioid Dependence
    10. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part VIII. Japanese Forum on Nicotine and Drug Dependence Studies
    11. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part IX. Nicotine and Marijuana
    12. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part X. Organic Solvent and Miscellaneous
    13. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part XI. Approaches to Pharmacotherapy for Drug Dependence
    14. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part XII. Perinatal Exposure of Nicotine, Cocaine, Amphetamines, and Heroin: Neurobehavioral and Neurochemical Outcomes
    1. Psychostimulants and Vesicle Trafficking: A Novel Mechanism and Therapeutic Implications (pages 146–150)

      GLEN R. HANSON, VERONICA SANDOVAL, EVAN RIDDLE and ANNETTE E. FLECKENSTEIN

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1316.019

    2. Similarities between Methamphetamine Toxicity and Proteasome Inhibition (pages 162–170)

      F FORNAI, P LENZI, M GESI, M FERRUCCI, G LAZZERI, L CAPOBIANCO, A de BLASI, G BATTAGLIA, F NICOLETTI, S RUGGIERI and A PAPARELLI

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1316.021

    3. Effects of Repeated Low Doses of MDMA on EEG Activity and Fluoro-Jade B Histochemistry (pages 181–188)

      F FORNAI, M GESI, P LENZI, M FERRUCCI, G LAZZERI, C PIZZANELLI, A PELLEGRINI, G BATTAGLIA, S RUGGIERI and A PAPARELLI

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1316.023

    4. Effects of “Legal X” Piperazine Analogs on Dopamine and Serotonin Release in Rat Brain (pages 189–197)

      MICHAEL H. BAUMANN, ROBERT D. CLARK, ALLISON G. BUDZYNSKI, JOHN S. PARTILLA, BRUCE E. BLOUGH and RICHARD B. ROTHMAN

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1316.024

    5. Effects of N-Acetyl-l-Cysteine on the Reduction of Brain Dopamine Transporters in Monkey Treated with Methamphetamine (pages 231–235)

      KENJI HASHIMOTO, HIDEO TSUKADA, SHINGO NISHIYAMA, DAI FUKUMOTO, TAKEHAU KAKIUCHI, EIJI SHIMIZU and MASAOMI IYO

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1316.028

    6. Fos Expression Associated with the Discriminative Stimulus Effects of Methamphetamine in Rats (pages 236–241)

      NAN ZENG, AKIRA NAKAJIMA, JUE HE, ATSUMI NITTA, KIYOFUMI YAMADA and TOSHITAKA NABESHIMA

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1316.029

    7. The Altered Disposition of Methamphetamine in the Model of Methamphetamine-Induced Neurotoxicity (pages 248–256)

      KIYOYUKI KITAICHI, YUKIKO ITO, MASAYA FUKUDA, NAGISA AOYAMA, HIRONAO NAKAYAMA, KENZO TAKAGI and TAKAAKI HASEGAWA

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1316.031

    8. Social Isolation Stress Significantly Enhanced the Disruption of Prepulse Inhibition in Mice Repeatedly Treated with Methamphetamine (pages 257–266)

      HONGMEI DAI, HIROTOMO OKUDA, KENTARO IWABUCHI, EIKO SAKURAI, ZHONG CHEN, MOTOHISA KATO, KAZUIE IINUMA and KAZUHIKO YANAI

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1316.032

    9. Role of Mitochondrial Dysfunction in Neurotoxicity of MPP:+: Partial Protection of PC12 Cells by Acetyl-l-Carnitine (pages 267–273)

      ASHRAF VIRMANI, FRANCO GAETANI, ZBIGNIEW BINIENDA, ALEX XU, HELEN DUHART and SYED F. ALI

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1316.033

    10. Nefiracetam Attenuates Methamphetamine-Induced Discriminative Stimulus Effects in Rats (pages 274–278)

      YIJIN YAN, TOMOKO MIZUNO, ATSUMI NITTA, KIYOFUMI YAMADA and TOSHITAKA NABESHIMA

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1316.034

  6. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part V. Biological Markers and Molecular Mechanisms of Methamphetamine Psychosis

    1. Top of page
    2. Frontmatter
    3. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part I. Molecular Genetics of Substance Abuse-Related Disorders
    4. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part II. Molecular Genetics of Psychostimulant Dependence and Toxicity: Gene Expression and Animal Models
    5. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part III. Knockout/Transgenic Approaches to Psychostimulant-Induced Neurotoxicity
    6. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part IV. Neurodegeneration, Neuroprotection in Substituted Amphetamine-Induced Neurotoxicity
    7. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part V. Biological Markers and Molecular Mechanisms of Methamphetamine Psychosis
    8. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part VI. Molecular and Neural Mechanisms of Cocaine: Dopamine Hypothesis
    9. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part VII. Cellular and Molecular Bases of Opioid Dependence
    10. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part VIII. Japanese Forum on Nicotine and Drug Dependence Studies
    11. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part IX. Nicotine and Marijuana
    12. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part X. Organic Solvent and Miscellaneous
    13. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part XI. Approaches to Pharmacotherapy for Drug Dependence
    14. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part XII. Perinatal Exposure of Nicotine, Cocaine, Amphetamines, and Heroin: Neurobehavioral and Neurochemical Outcomes
    1. A Polymorphism of DRD2 Gene and Brain Atrophy in Methamphetamine Psychosis (pages 307–315)

      M HARANO, N UCHIMURA, H ABE, M ISHIBASHI, N IIDA, K YANAGIMOTO, T TANAKA, H MAEDA, I SORA, M IYO, T KOMIYAMA, M YAMADA, Y SEKINE, T INADA, N OZAKI and H UJIKE

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1316.038

    2. Gene Polymorphisms of the Mu Opioid Receptor in Methamphetamine Abusers (pages 316–324)

      SOICHIRO IDE, HIDEAKI KOBAYASHI, KEIKO TANAKA, HIROSHI UJIKE, YOSHIMOTO SEKINE, NORIO OZAKI, TOSHIYA INADA, MUTSUO HARANO, TOKUTARO KOMIYAMA, MITSUHIKO YAMADA, MASAOMI IYO, KAZUTAKA IKEDA and ICHIRO SORA

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1316.039

    3. Study of Association between α-Synuclein Gene Polymorphism and Methamphetamine Psychosis/Dependence (pages 325–334)

      HIDEAKI KOBAYASHI, SOICHIRO IDE, JUNKO HASEGAWA, HIROSHI UJIKE, YOSHIMOTO SEKINE, NORIO OZAKI, TOSHIYA INADA, MUTSUO HARANO, TOKUTARO KOMIYAMA, MITSUHIKO YAMADA, MASAOMI IYO, HAO-WEI SHEN, KAZUTAKA IKEDA and ICHIRO SORAA

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1316.040

  7. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part VI. Molecular and Neural Mechanisms of Cocaine: Dopamine Hypothesis

    1. Top of page
    2. Frontmatter
    3. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part I. Molecular Genetics of Substance Abuse-Related Disorders
    4. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part II. Molecular Genetics of Psychostimulant Dependence and Toxicity: Gene Expression and Animal Models
    5. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part III. Knockout/Transgenic Approaches to Psychostimulant-Induced Neurotoxicity
    6. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part IV. Neurodegeneration, Neuroprotection in Substituted Amphetamine-Induced Neurotoxicity
    7. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part V. Biological Markers and Molecular Mechanisms of Methamphetamine Psychosis
    8. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part VI. Molecular and Neural Mechanisms of Cocaine: Dopamine Hypothesis
    9. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part VII. Cellular and Molecular Bases of Opioid Dependence
    10. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part VIII. Japanese Forum on Nicotine and Drug Dependence Studies
    11. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part IX. Nicotine and Marijuana
    12. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part X. Organic Solvent and Miscellaneous
    13. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part XI. Approaches to Pharmacotherapy for Drug Dependence
    14. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part XII. Perinatal Exposure of Nicotine, Cocaine, Amphetamines, and Heroin: Neurobehavioral and Neurochemical Outcomes
    1. Role of Cdk5 in Drug Abuse and Plasticity (pages 335–344)

      DAVID R. BENAVIDES and JAMES A. BIBB

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1316.041

    2. Cocaine Downregulates the Expression of the Mitochondrial Genome in Rat Brain (pages 345–350)

      JEAN-BERNARD DIETRICH, RAPHAËL POIRIER, DOMINIQUE AUNIS and JEAN ZWILLER

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1316.042

    3. Repetitive Cocaine Administration Decreases Neurogenesis in Adult Rat Hippocampus (pages 351–362)

      M YAMAGUCHI, T SUZUKI, T SEKI, T NAMBA, R JUAN, H ARAI, T HORI and T ASADA

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1316.043

    4. CART Peptides: Modulators of Mesolimbic Dopamine, Feeding, and Stress (pages 363–369)

      GERALDINA DOMINGUEZ, ALEXANDRA VICENTIC, EMANUELE MIRAGLIA DEL GIUDICE, JASON JAWORSKI, RICHARD G. HUNTER and MICHAEL J. KUHAR

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1316.044

  8. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part VII. Cellular and Molecular Bases of Opioid Dependence

    1. Top of page
    2. Frontmatter
    3. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part I. Molecular Genetics of Substance Abuse-Related Disorders
    4. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part II. Molecular Genetics of Psychostimulant Dependence and Toxicity: Gene Expression and Animal Models
    5. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part III. Knockout/Transgenic Approaches to Psychostimulant-Induced Neurotoxicity
    6. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part IV. Neurodegeneration, Neuroprotection in Substituted Amphetamine-Induced Neurotoxicity
    7. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part V. Biological Markers and Molecular Mechanisms of Methamphetamine Psychosis
    8. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part VI. Molecular and Neural Mechanisms of Cocaine: Dopamine Hypothesis
    9. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part VII. Cellular and Molecular Bases of Opioid Dependence
    10. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part VIII. Japanese Forum on Nicotine and Drug Dependence Studies
    11. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part IX. Nicotine and Marijuana
    12. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part X. Organic Solvent and Miscellaneous
    13. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part XI. Approaches to Pharmacotherapy for Drug Dependence
    14. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part XII. Perinatal Exposure of Nicotine, Cocaine, Amphetamines, and Heroin: Neurobehavioral and Neurochemical Outcomes
    1. Negative Regulation of Opioid Receptor-G Protein-Ca2+ Channel Pathway by the Nootropic Nefiracetam (pages 389–397)

      MITSUNOBU YOSHII, TAIJI FURUKAWA, YOSHIYASU OGIHARA, SHIGEO WATABE, TADASHI SHIOTANI, YASURO ISHIKAWA, MASAO NISHIMURA and TOSHIHIDE NUKADA

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1316.048

    2. Possible Pharmacotherapy of the Opioid κ Receptor Agonist for Drug Dependence (pages 404–413)

      KO HASEBE, KOJI KAWAI, TOMOHIKO SUZUKI, KUNIAKI KAWAMURA, TOSHIAKI TANAKA, MINORU NARITA, HIROSHI NAGASE and TSUTOMU SUZUKI

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1316.050

    3. A Single Exposure to Morphine Induces Long-Lasting Hyporeactivity of Rat Caudate Putamen Dopaminergic Nerve Terminals (pages 414–423)

      FREDERICO C. PEREIRA, SANDRA D. SANTOS, CARLOS F. RIBEIRO, SYED F. ALI and TICE R. MACEDO

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1316.051

  9. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part VIII. Japanese Forum on Nicotine and Drug Dependence Studies

    1. Top of page
    2. Frontmatter
    3. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part I. Molecular Genetics of Substance Abuse-Related Disorders
    4. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part II. Molecular Genetics of Psychostimulant Dependence and Toxicity: Gene Expression and Animal Models
    5. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part III. Knockout/Transgenic Approaches to Psychostimulant-Induced Neurotoxicity
    6. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part IV. Neurodegeneration, Neuroprotection in Substituted Amphetamine-Induced Neurotoxicity
    7. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part V. Biological Markers and Molecular Mechanisms of Methamphetamine Psychosis
    8. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part VI. Molecular and Neural Mechanisms of Cocaine: Dopamine Hypothesis
    9. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part VII. Cellular and Molecular Bases of Opioid Dependence
    10. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part VIII. Japanese Forum on Nicotine and Drug Dependence Studies
    11. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part IX. Nicotine and Marijuana
    12. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part X. Organic Solvent and Miscellaneous
    13. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part XI. Approaches to Pharmacotherapy for Drug Dependence
    14. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part XII. Perinatal Exposure of Nicotine, Cocaine, Amphetamines, and Heroin: Neurobehavioral and Neurochemical Outcomes
    1. Drug Abuse in China (pages 439–445)

      ZHAO CHENGZHENG, LIU ZHIMIN, ZHAO DONG, LIU YANHONG, LIANG JIANHUI, TANG YILANG, LIU ZEYUAN and ZHENG JIWANG

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1316.054

    2. Recent Trends of Drug Abuse and Drug-Associated Deaths in Korea (pages 458–464)

      HEESUN CHUNG, MEEJUNG PARK, EUNYOUNG HAHN, HAEYOUNG CHOI, HWAKYUNG CHOI and MIAE LIM

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1316.056

    3. Influence of Genetic Variations of Ethanol-Metabolizing Enzymes on Phenotypes of Alcohol-Related Disorders (pages 472–480)

      SUSUMU HIGUCHI, SACHIO MATSUSHITA, TOSHIHIRO MASAKI, AKIRA YOKOYAMA, MITSURU KIMURA, GO SUZUKI and HITOSHI MOCHIZUKI

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1316.058

    4. Clinical Features of Nicotine Dependence Compared with Those of Alcohol, Methamphetamine, and Inhalant Dependence (pages 481–488)

      HISATSUGU MIYATA, JUNKO KONO, SADANOBU USHIJIMA, TOMOJI YANAGITA, KATSUMASA MIYASATO and KENJI FUKUI

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1316.059

  10. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part IX. Nicotine and Marijuana

    1. Top of page
    2. Frontmatter
    3. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part I. Molecular Genetics of Substance Abuse-Related Disorders
    4. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part II. Molecular Genetics of Psychostimulant Dependence and Toxicity: Gene Expression and Animal Models
    5. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part III. Knockout/Transgenic Approaches to Psychostimulant-Induced Neurotoxicity
    6. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part IV. Neurodegeneration, Neuroprotection in Substituted Amphetamine-Induced Neurotoxicity
    7. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part V. Biological Markers and Molecular Mechanisms of Methamphetamine Psychosis
    8. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part VI. Molecular and Neural Mechanisms of Cocaine: Dopamine Hypothesis
    9. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part VII. Cellular and Molecular Bases of Opioid Dependence
    10. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part VIII. Japanese Forum on Nicotine and Drug Dependence Studies
    11. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part IX. Nicotine and Marijuana
    12. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part X. Organic Solvent and Miscellaneous
    13. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part XI. Approaches to Pharmacotherapy for Drug Dependence
    14. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part XII. Perinatal Exposure of Nicotine, Cocaine, Amphetamines, and Heroin: Neurobehavioral and Neurochemical Outcomes
    1. Nicotine Attenuates Relapse to Methamphetamine-Seeking Behavior (Craving) in Rats (pages 504–507)

      TAKATO HIRANITA, KUSNANDAR ANGGADIREDJA, CHIE FUJISAKI, SHIGENORI WATANABE and TSUNEYUKI YAMAMOTO

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1316.062

  11. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part X. Organic Solvent and Miscellaneous

    1. Top of page
    2. Frontmatter
    3. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part I. Molecular Genetics of Substance Abuse-Related Disorders
    4. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part II. Molecular Genetics of Psychostimulant Dependence and Toxicity: Gene Expression and Animal Models
    5. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part III. Knockout/Transgenic Approaches to Psychostimulant-Induced Neurotoxicity
    6. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part IV. Neurodegeneration, Neuroprotection in Substituted Amphetamine-Induced Neurotoxicity
    7. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part V. Biological Markers and Molecular Mechanisms of Methamphetamine Psychosis
    8. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part VI. Molecular and Neural Mechanisms of Cocaine: Dopamine Hypothesis
    9. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part VII. Cellular and Molecular Bases of Opioid Dependence
    10. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part VIII. Japanese Forum on Nicotine and Drug Dependence Studies
    11. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part IX. Nicotine and Marijuana
    12. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part X. Organic Solvent and Miscellaneous
    13. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part XI. Approaches to Pharmacotherapy for Drug Dependence
    14. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part XII. Perinatal Exposure of Nicotine, Cocaine, Amphetamines, and Heroin: Neurobehavioral and Neurochemical Outcomes
    1. 4-Methylpyrazole Decreases 1,4-Butanediol Toxicity by Blocking Its in Vivo Biotransformation to γ-Hydroxybutyric Acid (pages 528–537)

      LAWRENCE S. QUANG, MALHAR C. DESAI, MICHAEL W. SHANNON, ALAN D. WOOLF and TIMOTHY J. MAHER

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1316.065

    2. Comparison of G-Protein Selectivity of Human 5-HT2C and 5-HT1A Receptors (pages 570–577)

      MITSUKO OKADA, DAVID GOLDMAN, MARKKU LINNOILA, NAKAO IWATA, NORIO OZAKI and JOHN K. NORTHUP

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1316.070

  12. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part XI. Approaches to Pharmacotherapy for Drug Dependence

    1. Top of page
    2. Frontmatter
    3. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part I. Molecular Genetics of Substance Abuse-Related Disorders
    4. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part II. Molecular Genetics of Psychostimulant Dependence and Toxicity: Gene Expression and Animal Models
    5. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part III. Knockout/Transgenic Approaches to Psychostimulant-Induced Neurotoxicity
    6. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part IV. Neurodegeneration, Neuroprotection in Substituted Amphetamine-Induced Neurotoxicity
    7. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part V. Biological Markers and Molecular Mechanisms of Methamphetamine Psychosis
    8. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part VI. Molecular and Neural Mechanisms of Cocaine: Dopamine Hypothesis
    9. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part VII. Cellular and Molecular Bases of Opioid Dependence
    10. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part VIII. Japanese Forum on Nicotine and Drug Dependence Studies
    11. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part IX. Nicotine and Marijuana
    12. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part X. Organic Solvent and Miscellaneous
    13. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part XI. Approaches to Pharmacotherapy for Drug Dependence
    14. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part XII. Perinatal Exposure of Nicotine, Cocaine, Amphetamines, and Heroin: Neurobehavioral and Neurochemical Outcomes
    1. Monitoring Drug-Induced Neurodegeneration by Imaging of Peripheral Benzodiazepine Receptors (pages 584–589)

      BEN AVI WEISSMAN, RACHEL BRANDEIS, ERAN GILAT, GIORA COHEN, DAVID ALKALAY, ISHAI RABINOVITZ, HAGAR SONEGO and LILY RAVEH

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1316.072

  13. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part XII. Perinatal Exposure of Nicotine, Cocaine, Amphetamines, and Heroin: Neurobehavioral and Neurochemical Outcomes

    1. Top of page
    2. Frontmatter
    3. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part I. Molecular Genetics of Substance Abuse-Related Disorders
    4. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part II. Molecular Genetics of Psychostimulant Dependence and Toxicity: Gene Expression and Animal Models
    5. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part III. Knockout/Transgenic Approaches to Psychostimulant-Induced Neurotoxicity
    6. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part IV. Neurodegeneration, Neuroprotection in Substituted Amphetamine-Induced Neurotoxicity
    7. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part V. Biological Markers and Molecular Mechanisms of Methamphetamine Psychosis
    8. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part VI. Molecular and Neural Mechanisms of Cocaine: Dopamine Hypothesis
    9. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part VII. Cellular and Molecular Bases of Opioid Dependence
    10. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part VIII. Japanese Forum on Nicotine and Drug Dependence Studies
    11. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part IX. Nicotine and Marijuana
    12. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part X. Organic Solvent and Miscellaneous
    13. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part XI. Approaches to Pharmacotherapy for Drug Dependence
    14. Current Status of Drug Dependence/Abuse Studies: Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Part XII. Perinatal Exposure of Nicotine, Cocaine, Amphetamines, and Heroin: Neurobehavioral and Neurochemical Outcomes
    1. Convergent Effects on Cell Signaling Mechanisms Mediate the Actions of Different Neurobehavioral Teratogens: Alterations in Cholinergic Regulation of Protein Kinase C in Chick and Avian Models (pages 595–601)

      JOSEPH YANAI, AVITAL BEER, RABAB HULEIHEL, MICHAL IZRAEL, SOFIA KATZ, YAARIT LEVI, ISRAEL ROZENBOIM, SHIRI P. YANIV and THEODORE A. SLOTKIN

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1316.074

    2. Effects of Neonatal Exposure to Methamphetamine: Catecholamine Levels in Brain Areas of the Developing Rat (pages 602–611)

      JOANA GOMES-DA-SILVA, ROSARIO de MIGUEL, JAVIER FERNÁNDEZ-RUIZ, TERESA SUMMAVIELLE and M AMÉLIA TAVARES

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1316.075

    3. Abnormal Immunoreactivity to Serotonin in Cerebellar Purkinje Cells after Neonatal Cocaine Exposure (pages 630–637)

      TERESA SUMMAVIELLE, CECILIA J. ALVES, PEDRO R.R. MONTEIRO and MARIA AMELIA TAVARES

      Version of Record online: 12 JAN 2006 | DOI: 10.1196/annals.1316.078

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